Active-site studies of enzymes by secondary structure prediction and by molecular modeling

Cid, H.; Bunster, M

Keywords: sequence, dynamics, model, acid, inhibition, enzyme, activation, tertiary, animals, protein, structure, beta, ray, site, bisphosphatase, x-rays, molecular, data, active, article, secondary, hydrophobicity, venom, fructose, folding, crystallography, snake, phospholipase, amino, X, Models,, lactamase, 2,6, bisphosphate, a2, Structure,

Abstract

Since the determination of the tertiary structure by X-ray crystallography has been achieved only for a limited number of proteins, alternative approaches are being sought. In this article, the use of secondary structure prediction and of molecular modeling is discussed. Several examples are analyzed in detail.

Más información

Título de la Revista: Biological Research
Volumen: 29
Número: 1
Editorial: Springer
Fecha de publicación: 1996
Página de inicio: 77
Página final: 100
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029930008&partnerID=q2rCbXpz