Man

Francisco Javier Sáez Orellana

Investigador asistente

Universidad de Concepción

Concepción, Chile

Líneas de Investigación


Neuroscience, Metabolic control, PPAR, Fatty acid metabolism, Alzheimer's disease, neurodegeneration

Educación

  •  Cellular and Molecular Biology, UNIVERSIDAD DE CONCEPCION. Chile, 2015
  •  Biochemistry, Universidad de Concepción. Chile, 2010

Experiencia Académica

  •   Postdoctoral Researcher Full Time

    UNIVERSITE CATHOLIQUE DE LOUVAIN

    Institute of Neuroscience

    Brussels, Bélgica

    2018 - 2020

Experiencia Profesional

  •   Research assistant Part Time

    Universidad de Concepción

    Concepción, Chile

    2021 - At present

  •   Teaching Assitant Part Time

    Universidad de Concepción

    Chile

    2022 - At present

  •   Lecturer Part Time

    Universidad San Sebastian

    Concepción, Chile

    2022 - 2022

  •   Teaching assistant Part Time

    Universidad de Concepción

    Concepción, Chile

    2015 - 2017

Premios y Distinciones

  •   Becas Chile Postdoctorado en el Extranjero

    CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNOLOGICAS

    Chile, 2018

    Beca para la realización de postdoctorado en el extranjero

  •   Henri Nestlé

    NESTLE CHILE S.A.

    Chile, 2012

    Versión Científica-Nutrición, por el artículo Synaptic silencing and plasma membrane dyshomeostasis induced by amyloid-? peptide are prevented by Aristotelia chilensis enriched extract


 

Article (9)

Microglial Activation Modulated by P2X4R in Ischemia and Repercussions in Alzheimer's Disease
Regulation of PPAR alpha by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity
Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor alpha
A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-beta Peptide Toxicity
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease
ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of beta-amyloid peptide in hippocampal neurons
Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model
Synaptic Silencing and Plasma Membrane Dyshomeostasis Induced by Amyloid-beta Peptide are Prevented by Aristotelia chilensis Enriched Extract
Synaptic Failure and Adenosine Triphosphate Imbalance Induced by Amyloid-beta Aggregates Are Prevented by Blueberry-Enriched Polyphenols Extract

EditorialMaterial (1)

Neuroactive alkaloids that modulate the neuronal nicotinic receptor and provide neuroprotection in an Alzheimer's disease model: the case of Teline monspessulana

Review (1)

Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders
9
Francisco Sáez

Investigador asistente

Fisiología

Universidad de Concepción

Concepción, Chile

6
JORGE FUENTEALBA

Dean

Physiology

UNIVERISDAD DE CONCEPCION

Concepcion, Chile

4
JOSE GUZMAN

Full professor

Fisiología

Universidad de Concepción

Concepcion, Chile

3
Claudia Perez

Academic

Botany

University of Concepción

Concepción, Chile

3
Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

2
JOSE BECERRA

Professor

Botany Department

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

2
Pamela Godoy

Colaboradora académica

Fisiología

Universidad de Concepción

Concepcion, Chile

1
Camila Bastidas

Docente

Universidad de Concepción

Concepción, Chile

1
Juan Araya

Instructor

Análisis Instrumental

Universidad de Concepción

Concepción, Chile

1
Carlos Oyanedel

Research Assistant

Institute of Medical Psychology and Behavioral Neurobiology

Eberhard Karl University of Tübingen

Tübingen, Alemania