Man

Nicolas Andres Crossley Karmelic

Assistant Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Neuroimaging of psychosis, especially the early stages of the disorder. Particularly interested in network approaches (graph analysis) to understand brain disorders, using functional MRI, DTI, and meta-data.

Educación

  •  Médico Cirujano, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2004
  •  Medical Neurosciences, CHARITE UNIVERSITATSMEDEZIN BERLIN. Alemania, 2006
  •  Neuroimaging, KINGS COLLEGE LONDON. Reino Unido, 2014
  •  General Adult Psychiatrist (CCT), General Medical Council . Reino Unido, 2016
  •  Member of the Royal College of Psychiatrists (MRCPsych), Royal College of Psychiatrists UK. Reino Unido, 2009

Experiencia Académica

  •   Wellcome Clinical Research Fellow Full Time

    KINGS COLLEGE LONDON

    Institute of Psychiatry

    London, Reino Unido

    2011 - 2014

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2014 - At present

  •   NIHR Academic Clinical Fellow Other

    KINGS COLLEGE LONDON

    Institute of Psychiatry

    London, Reino Unido

    2008 - 2011

Experiencia Profesional

  •   Wellcome Clinical Research Fellow Full Time

    King's College London

    London, Reino Unido

    2011 - 2014

  •   National Institute of Health Research UK - Academic Clinical Fellow Full Time

    King's College London

    London, Reino Unido

    2008 - 2011

  •   Senior House Officer in Psychiatry Full Time

    North Essex Partnership NHS Foundation Trust

    London, Chile

    2007 - 2008

  •   Senior House Officer in Psychiatry Full Time

    South London and Maudsley NHS Foundation Trust

    London, Chile

    2006 - 2007

  •   Médico General Part Time

    P. Universidad Católica de Chile - Red de Salud

    Santiago, Chile

    2004 - 2004

  •   Médico de Urgencia Part Time

    Servicio Nacional de Salud Médico Sur Oriente

    Santiago, Chile

    2004 - 2004

  •   Psychiatrist Part Time

    Liga Chile contra la Epilepsia

    Santiago, Chile

    2014 - At present

  •   Assistant Professor Full Time

    P. Universidad Católica de Chile

    Santiago, Chile

    2014 - At present

Formación de Capital Humano


- Supervisor of 1 completed PhD student (Tomás Labbé, Neurociencias UC 2018), and 3 current students (George Gifford, King's College London; Angeles Tepper, Neurociencias UC; Carolina González, Neurociencias UC).
- Lecturer and in charge of undergraduate medical studies of Cognitive Science - chapter within the Neurophysiology course for Medical undergraduate students at Pontificia Universidad Catolica. Lecturer for PhD students at P. Universidad Catolica - specifically leads a course on imaging for cognitive sciences.
- Supervisor of BSc project (Jessica Scott, KCL 2011-2012).
- Lecturer for several Institute of Psychiatry, King's College London, programmes: MSc Mental Health Research (2009, 2013), MRCPsych course (2011 and 2012).
- Facilitator for Interprofessional Education Course KCL (2008).
- Teaching assistant in Gross Anatomy, PUC (1997).


Premios y Distinciones

  •   PhD of the year

    KINGS COLLEGE LONDON

    Reino Unido, 2014

    Prize to the best PhD of the year of the Department of Psychosis Studies.

  •   Wellcome Clinical Research Training Fellowship

    KINGS COLLEGE LONDON

    Chile, 2010

    Award given competitively to doctors in the UK who want to continue an academic career.

  •   NIHR Clinical Academic Fellow

    KINGS COLLEGE LONDON

    Chile, 2007

    Competitive award for doctors in training in the UK given by the National Institute of Health Research UK. It is a open to any specialty, allowing the holder to spend some of their time pursuing academic interests.

  •   Best student of the generation

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2003

    Best student of the cohort graduating that year in Medical School, PUC.

  •   Top national score in Medical Exam

    Asociacion de Facultades de Medicina Chile (ASOFAMECH)

    Chile, 2003

    National top score in exam taken by all medical graduates of that year in Chile

  •   Honor fee

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2001

    Award given to the best student of the generation of that year in Medical School.

  •   Honor fee

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 1998

    Award given to the best student of the generation of that year in Medical School.

  •   Beca Santander para académicos jóvenes

    Santander Universidades

    Chile, 2017

    Scholarship providing funds to increase collaborative work with the Universidad Federal de Sao Paulo, Brazil.


 

Article (29)

A pupil size, eye-tracking and neuropsychological dataset from ADHD children during a cognitive task
High prevalence of metabolic alterations in Latin American patients at initial stages of psychosis
Using fMRI connectivity to define a treatment-resistant form of post-traumatic stress disorder
Early treatment resistance in a Latin-American cohort of patients with schizophrenia.
Connectomic correlates of response to treatment in first-episode psychosis.
Coordinated brain development=> exploring the synchrony between changes in grey and white matter during childhood maturation.
Network-Level Dysconnectivity in Drug-Naïve First-Episode Psychosis=> Dissociating Transdiagnostic and Diagnosis-Specific Alterations.
Pupil Size Tracks Attentional Performance In Attention-Deficit/Hyperactivity Disorder
Structural Network Disorganization in Subjects at Clinical High Risk for Psychosis.
Connectome hubs at resting state in children and adolescents: Reproducibility and psychopathological correlation
Coordinated brain development: exploring the synchrony between changes in grey and white matter during childhood maturation
Default mode network maturation and psychopathology in children and adolescents
HPA-axis function and grey matter volume reductions: imaging the diathesis-stress model in individuals at ultra-high risk of psychosis
Whole-Brain Atrophy Rate in Idiopathic Parkinson's Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy
Decreased centrality of subcortical regions during the transition to adolescence: A functional connectivity study
Neuroimaging distinction between neurological and psychiatric disorders.
Quantitative Prediction of Individual Psychopathology in Trauma Survivors Using Resting-State fMRI
The hubs of the human connectome are generally implicated in the anatomy of brain disorders.
Cognitive relevance of the community structure of the human brain functional coactivation network.
Neurophysiological alterations in the prepsychotic phases.
Gray matter alterations related to P300 abnormalities in subjects at high risk for psychosis: Longitudinal MRI-EEG study
White matter alterations related to P300 abnormalities in individuals at high risk for psychosis: an MRI-EEG study
Efficacy of atypical v. typical antipsychotics in the treatment of early psychosis: meta-analysis.
Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosis.
Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials.
Renal transplants with delayed graft function show decreased renal function despite monitoring with postabsorptive levels
[Critical appraisal: Subcutaneous adjusted-dose unfractionated heparin vs fixed-dose low-molecular-weight heparin in the initial treatment of venous thromboembolism. Prandoni P, Carnovali M, Marchiori A, Galilei investigators. Arch Intern Med 2004; 164: 1077-83].
Age effects on the default mode and control networks in typically developing children.
Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach.

BookSection (3)

Neurophysiological alterations in the pre-psychotic phases
The Acute Antidepressant Effects of Lithium: from Monotherapy to Augmentation Therapy in Major Depressive Episodes
The Position of Lithium in International and National Guidelines for the Treatment of Mood Disorders

Proyecto (3)

Ibero-American Network for the study of early psychosis
A CONNECTOMIC NEUROIMAGING STUDY OF THE 22Q11 DELETION SYNDROME: A WINDOW INTO SCHIZOPHRENIA AND ITS GENETIC CAUSES
Network dynamics and neural circuits of the brain during resting-state in health and disease

Review (1)

Imaging Social and Environmental Factors as Modulators of Brain Dysfunction: Time to Focus on Developing Non-Western Societies
27
Nicolas Crossley

Assistant Professor

Psiquiatría

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Tomás Ossandón

Associate Professor

Medical School, Department of Psychiatry

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Juan Undurraga

Psychiatrist

Neurología y Psiquiatría

Facultad de Medicina Clínica Alemana Universidad del Desarrollo

Santiago, Chile

2
Francisco Aboitiz

Profesor

Psychiatry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

santiago, Chile

2
ALFONSO GONZALEZ

PROFESOR ASISTENTE

SALUD MENTAL

Universidad Finis Terrae

santiago, Chile

2
Daniel Rojas

Profesor

Universidad Diego Portales

Santiago, Chile

1
Carlos Guevara

Profesor Asistente

Neurologia y Neurocirugía

Hospital Clínico de la Universidad de Chile

Santiago, Chile