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loreto paulina parra atala

Assitant Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Protein Engineering Directed evolution Industrial Biotechnology Biocatalysis

Engineering Sciences, mention in chemistry, UNIVERSIDAD DE CHILE. Chile, 2011
Molecular Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2004
Molecular Biotecnology Engineer, UNIVERSIDAD DE CHILE. Chile, 2006

Assistant Professor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Engineering

Santiago, Chile

2013 - At present

Internship Full Time

GrupoBios

Chile

2004 - 2005
Postdoctoral researcher Full Time

Max-Planck-Institut für Kohlenforschung

Alemania

2011 - 2012

Courses at the University:
- Engineering Challenges
- Cell Biology
- Protein Engineering and Biocatalysis

Valedictorian Award

UNIVERSIDAD DE CHILE

Chile, 2004

Ranked first amongst a class of 35 students graduated of Bachelor in Molecular Biotechnology Engineering - Granted by the Faculty of Science of the Universidad de Chile for academic excellence (October 2004).
PhD Conicyt Scholarship

CONICYT

Chile, 2006

Granted by the Chilean Government to finance Ph.D studies in Chilean Universities (March 2006).
Meeting of Nobel Laureates

Scientific Review Panel of the Lindau Council.

Alemania, 2009

Accepted as a participant of the 59th Meeting of Nobel Prize Winners in Chemistry – Granted by the Scientific Review Panel of the Lindau Council. (Lindau, Germany. June 28th to July 3rd 2009).
Post Conference Programme in Baden-Württemberg

Baden-Wuerttemberg state government

Chile, 2009

Accepted as a participant of the Post-Conference Programme Baden-Wuerttemberg of the 59th Meeting of Nobel Laureates for 20 candidates. – Invitation of the Baden-Wuerttemberg state government (Federal state of Baden-Württemberg, Germany. July 4th-8th, 2009).
Postdoctoral scholarship “Max Planck Society”

Max-Planck-Institut für Kohlenforschung

Chile, 2011

Postdoctoral grant


Active Site Flexibility as a Hallmark for Efficient PET Degradation by I-sakaiensis PETase Ramirez-Sarmiento, Cesar A.; Narui, Yoshie; Fecker, Tobias; Sotomayor, Marcos; Engelberger, Felipe; Parra, Loreto P.; Galaz-Davison, Pablo Article ISI SCOPUS BIOPHYSICAL JOURNAL (2018)
Protein Engineering for Nicotinamide Coenzyme Specificity in Oxidoreductases: Attempts and Challenge Parra, Loreto P.; Chanique, Andrea M. Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2018)
Relevance of Local Flexibility Near the Active Site for Enzymatic Catalysis: Biochemical Characterization and Engineering of Cellulase Cel5A From Bacillus agaradherans Saavedra, Juan M.; Azócar, Mauricio A.; Rodríguez, Vida; Ramírez-Sarmiento, César A.; Andrews, Barbara A.; Asenjo, Juan A.; Parra, Loreto P. Article ISI SCOPUS BIOTECHNOLOGY JOURNAL (2018)
One-step combined focused epPCR and saturation mutagenesis for thermostability evolution of a new cold-active xylanase. Juan P. Acevedo; Manfred T. Reetz; Juan A. Asenjo; Loreto P. Parra Article Enzyme Microbial Technology (2017)
Discovery, Molecular Mechanisms and Industrial Applications of Cold-Active Enzymes Santiago, Margarita; Ramírez-Sarmiento, César A.; Zamora, Ricardo A.; Parra, Loreto P. Article Frontiers in Microbiology (2016)
Directed evolution of phenylacetone monooxygenase as an active catalyst for the baeyer-villiger conversion of cyclohexanone to caprolactone Parra, LP; Acevedo, JP; Reetz, MT Article ISI SCOPUS Biotechnology and Bioengineering (2015)
Identification of lipase encoding genes from Antarctic seawater bacteria using degenerate primers: Expression of a cold-active lipase with high specific activity Parra L.P.; Espina, G; Devia, J; Salazar, O; Andrews B.; Asenjo, J.A Article ISI SCOPUS ENZYME AND MICROBIAL TECHNOLOGY (2015)
Directed Evolution by Using Iterative Saturation Mutagenesis Based on Multiresidue Site Loreto P. Parra; Manfred T. Reetz Article ChemBioChem (2013)
Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis Kille, S; Acevedo-Rocha, CG; Parra, LP; Zhang, ZG; Opperman, DJ; Reetz, MT; Acevedo, JP Article ISI SCOPUS ACS Synthetic Biology (2013)
Protein Engineering of Stereoselective Baeyer–Villiger Monooxygenases Zhi-Gang Zhang; Loreto P. Parra; Manfred T. Reetz Article Chemistry - A European Journal (2012)
Cloning and fusion expression of a cold-active lipase from marine Antarctic origin Parra, LP; Reyes, F.; Acevedo, JP; Salazar, O; Andrews, BA; Asenjo, JA Article ISI SCOPUS ENZYME AND MICROBIAL TECHNOLOGY (2008)
Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique Acevedo, JP; Reyes, F.; Parra, LP; Salazar, O; Andrews, BA; Asenjo, JA Article ISI SCOPUS JOURNAL OF BIOTECHNOLOGY (2008)


Protein and DNA sequence encoding a cold adapted xylanase Parra, Loreto P.; Asenjo, Juan A.; ANDREWS, Barbara, A.; Acevedo, Juan P; Burzio, Luis O. Patent Grant (2014)
Variantes de fenilacetona monoxigenasa para la reacción Baeyer-Villiger de ciclohexanona Parra, Loreto P.; Acevedo, Juan P Patent Patent pending


Surfing the Blood Coagulation Cascade: Insight into the Vital Factor Xa NÃºÃ±ez-Navarro N.E.; Santana F.M.; Parra L.P.; Zacconi, F.C. Review ISI SCOPUS CURRENT MEDICINAL CHEMISTRY (2019)