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Cecilia Alejandra Silva Valenzuela

Investigador Principal

Centro de Estudios Cientificos

Valdivia, Chile

Mi línea de investigación utiliza genética microbiana para comprender la carrera armamentística entre bacterias y bacteriófagos. Nuestro objetivo es desarrollar o mejorar las herramientas de diagnóstico y/o terapias actuales contra patógenos humanos.

Doctor en Ciencias Biomédicas, Universidad de Chile. Chile, 2014
Magister en Bioquímica mención proteínas y biotecnología., Universidad de Chile. Chile, 2009
Bioquímico, Universidad de Chile. Chile, 2009
Licenciado en Bioquímica, Universidad de Chile. Chile, 2008

Asistente del Instructor en el curso “Advanced Bacterial Genetics” Other

COLD SPRING HARBOR LABORATORY

Estados Unidos

2016 - 2016
Profesor curso geómica y proteómica Other

UNIVERSIDAD SAN SEBASTIAN

Chile

2014 - 2014
Profesor curso geómica y proteómica Other

UNIVERSIDAD SAN SEBASTIAN

Chile

2015 - 2015
Profesor del curso de laboratorio microbiología avanzada Other

UNIVERSIDAD SAN SEBASTIAN

Chile

2013 - 2013
Profesor del curso de laboratorio de microbiologia Other

UNIVERSIDAD ANDRES BELLO

Chile

2008 - 2008

Asistente de Investigación Full Time

Universidad de Chile

Chile

2008 - 2009
Asistente de Investigación Full Time

Universidad de Chile

Chile

2013 - 2015
Postdoctoral Scholar Full Time

Tufts University

Boston, Estados Unidos

2015 - 2018
Investigador Principal Full Time

Centro de Estudios Cientificos

Valdivia, Chile

2019 - At present

2020 - Victor Fuentes Barrera. Programa de Magíster en Ciencias mención Microbiología. Universidad Austral de Chile

Pew Latin American Fellow in the Biomedical Sciences. Class 2016

PEW LATIN AMERICAN FELLOWS PROGRAM IN BIOMEDICAL SCIENCES

Estados Unidos, 2016

Pew Latin American Fellow in the Biomedical Sciences. Class 2016
Young Ambassador to Chile

American Society for Microbiology

Estados Unidos, 2014

Embajadora joven de la American Society of Microbiology para Chile (2014-2016)
Tabrisky Endowed Research Fund travel award

TUFTS UNIVERSITY

Estados Unidos, 2016

Tabrisky Endowed Research Fund travel award
mBio Junior Editor Board member

The American Society for Microbiology

Chile, 2022

Primera generación de entrenamiento para editores jóvenes para la revista mBio.


Prophage-Dependent Neighbor Predation Fosters Horizontal Gene Transfer by Natural Transformation Molina-Quiroz, Roberto C.; Dalia, Triana N.; Camilli, Andrew; Dalia, Ankur B.; Silva-Valenzuela, Cecilia A. Article ISI MSPHERE (2020)
Niche adaptation limits bacteriophage predation of Vibrio cholerae in a nutrient-poor aquatic environment Silva-Valenzuela, Cecilia A.; Camilli, Andrew Article ISI PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Vibrio cholerae residing in food vacuoles expelled by protozoa are more infectious in vivo Espinoza-Vergara, Gustavo; Noorian, Parisa; Silva-Valenzuela, Cecilia A.; Raymond, Benjamin B. A.; Allen, Christopher; Hoque, M. Mozammel; Sun, Shuyang; Johnson, Michael S.; Pernice, Mathieu; Kjelleberg, Staffan; Djordjevic, Steven P.; Labbate, Maurizio; Camilli, Andrew; McDougald, Diane Article ISI SCOPUS NATURE MICROBIOLOGY (2019)
Cyclic AMP Regulates Bacterial Persistence through Repression of the Oxidative Stress Response and SOS-Dependent DNA Repair in Uropathogenic Escherichia coli Molina-Quiroz, RC; Silva-Valenzuela, C; Brewster J; Castro-Nallar, E; Levy, S; Camilli A Article MBIO (2018)
Vibrio cholerae outer membrane vesicles inhibit bacteriophage infection Reyes-Robles, T; Dillard, RS.; Cairns, LS.; Silva-Valenzuela, CA; Housman, M; Ali, A; Wright, ER; Camilli A Article JOURNAL OF BACTERIOLOGY (2018)
Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interaction of Salmonella Enteritidis and Salmonella Typhi with murine and human macrophages Espinoza, RA; Silva-Valenzuela, CA; Amaya, FA; Urrutia, ÍM; Contreras, I; Santiviago, CA Article BIOLOGICAL RESEARCH (2017)
Growth arrest and a persister state enable resistance to osmotic shock and facilitate dissemination of Vibrio cholerae Silva-Valenzuela, Cecilia A.; Lazinski, David W.; Kahne, Shoshanna C.; Nguyen, Y.; Molina-Quiroz, Roberto C.; Camilli, Andrew Article ISI ISME JOURNAL (2017)
Analysis of Two Complementary Single-Gene Deletion Mutant Libraries of Salmonella Typhimurium in Intraperitoneal Infection of BALB/c Mice Silva-Valenzuela, CA; Molina-Quiroz, RC; Desai, P; Valenzuela C.; Porwollik, S; Zhao, M; Hoffman, RM; Andrews-Polymenis, H; Contreras, I; Santiviago, CA; McClelland, M Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2016)
O-antigen chain-length distribution in Salmonella enterica serovar Enteritidis is regulated by oxygen availability Silva-Valenzuela, CA; Velasquez, F; Penailillo, J; Garcias-Papayani, H; fernandez, P; Tobar, P; Contreras, I; Santiviago, CA; Alvarez, SA Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella Silva-Valenzuela C.A; Desai P.T.; Molina-Quiroz R.C; Pezoa, D; Zhang, Y.; Porwollik, S; Zhao, M; Hoffman R.M.; Contreras, I; Santiviago, C. A.; McClelland, M Article ISI SCOPUS ONCOTARGET (2016)
Exposure to sub-inhibitory concentrations of cefotaxime enhances the systemic colonization of Salmonella Typhimurium in BALB/c mice Molina-Quiroz, RC; Silva, CA; Molina, CF; Leiva, LE; Reyes-Cerpa, S; Contreras, I; Santiviago, CA Article ISI SCOPUS Open Biology (2015)
Defined Single-Gene and Multi-Gene Deletion Mutant Collections in Salmonella enterica sv Typhimurium Porwollik, S; Santiviago, CA; Cheng, P; Long F.; Desai, P; Fredlund, J; Srikumar, S; Silva, CA; Chu, WP; Chen X.; Canals, R; Reynolds, MM; Bogomolnaya, L; Shields C.; Cui, P; Guo, JB; Zheng Y.; Endicott-Yazdani, T; Yang, HJ; Maple, A; Ragoza, Y; Blondel CJ; Valenzuela C.; Andrews-Polymenis, H; McClelland, M Article ISI SCOPUS PLOS ONE (2014)
Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts Pezoa, D; Blondel CJ; Silva, CA; Yang, HJ; Andrews-Polymenis, H; Santiviago, CA; Contreras, I Article ISI SCOPUS VETERINARY RESEARCH (2014)
Infection of Mice by Salmonella enterica Serovar Enteritidis Involves Additional Genes That Are Absent in the Genome of Serovar Typhimurium Silva C.A.; Blondel, C. J.; Quezada, C. P.; Porwollik, S; Andrews-Polymenis H.L.; Toro C.S.; Zaldivar, M; Contreras, I; McClelland, M; Santiviago, C. A. Article ISI SCOPUS Infection and Immunity (2012)
Spontaneous Excision of the Salmonella enterica Serovar Enteritidis-specific Defective Prophage-Like Element phi SE14 Santiviago, CA; Blondel CJ; quezada cp; Silva, CA; Tobar, PM; Porwollik, S; McClelland, M; Andrews-Polymenis, HL; Toro, CS; Zaldivar, M; Contreras, I Article ISI SCOPUS Journal of Bacteriology (2010)
Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella Bravo D.; Silva C.; Carter, JA; Hoare, A; Alvarez, SA; Blondel CJ; Zaldivar, M; Valvano, MA; Contreras, I Article ISI SCOPUS JOURNAL OF MEDICAL MICROBIOLOGY (2008)


Impact of the oxidative stress response on natural competence of a water-borne bacterial pathogen Silva-Valenzuela Cecilia A Proyecto (2019)
Dynamics of phage predation on Vibrio cholerae in the environment and its impact on dissemination and transmission of cholera Silva-Valenzuela C.A Proyecto (2016)
Mecesup Project UCH0717 and the Sciences, Technology and Innovation Program for the Americas (STIPAs) a collaborative initiative between the University of California San Diego, the University of Chile and the Catholic University of Chile Silva-Valenzuela, Cecilia A Proyecto (2010)
Beca Doctorado Nacional Silva-Valenzuela, Cecilia A Proyecto (2009)