Img_20210626_122259.jpg_thumb90

Emma Rey Jurado

Professor/Researcher

Universidad del Desarrollo

Santiago, Chile

Líneas de Investigación


- Primary immunodeficiencies - Susceptibility to infections - Immunopathogenesis of respiratory viruses; - Host-pathogen interactions - Efficiency of drug-combinations against M. tuberculosis

Educación

  •  Biología. Especialidad Microbiología, UNIVERSIDAD AUTONOMA DE BARCELONA. España, 2007
  •  Doctor en Biología, UNIVERSIDAD DE BARCELONA. España, 2013

Experiencia Académica

  •   Postdoctorante Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile

    2014 - 2018

  •   Profesora Part Time

    Universidad Santo Tomás

    Chile

    2019 - 2020

  •   Professor/Researcher Full Time

    Universidad del Desarrollo

    Chile

    2020 - At present

Experiencia Profesional

  •   Estudiante predoctoral

    Hospital Clínico de Barcelona. Universidad de Barcelona

    España

    2008 - 2013

  •   Visitante predoctoral

    National Institute for Medical Research

    Reino Unido

    2011 - 2011

  •   Investigador postdoctoral

    Public Health Research Institute

    Estados Unidos

    2013 - 2014

  •   Postdoctorante Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2014 - 2018

  •   Profesora Part Time

    Universidad Santo Tomás

    Santiago, Chile

    2019 - At present

  •   Profesora/Postdoctorante Full Time

    Universidad del Desarrollo

    Chile

    2020 - At present

Formación de Capital Humano


I have mentored graduated and PhD students to obtain their degrees:

Álex López-Galvín, Master student at University of Barcelona.
Derek Ray, graduate student at Rutgers University.
Andrés Mansilla, PhD student at Pontificia Universidad Católica de Chile.
Nicolás Gálvez, PhD student at Pontificia Universidad Católica de Chile.


Difusión y Transferencia


I have presented our results at scientific meetings at national and international annual meetings including Federation of Clinical Immunology Societies (FOCIS) meetings, Congress of the Latin American Society of Immunology (ALAI) and Sociedad de Microbiología de Chile (SOMICH), Sociedad Española de Microbiología (SEIMC) and ESCMID. These events brought together national and international investigators, thus promoting collaborations in the field of immunology and translational biomedicine.
I were present in El Mostrador national newspaper on 4th November of 2015, contributing to better knowledge about Tuberculosis as well as the project granted by CONICYT. At such occasion, we were accessible to a significant number of people in Chile.


Premios y Distinciones

  •   Pumarola Award

    Societat Catalana de Malalties Infeccioses i Microbiologia Clínica i de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC)

    España, 2008

    Award “Agustí Pumarola” by the “ Societat Catalana de Malalties Infeccioses i Microbiología Clínica i de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC)” to develop a project entitled “Study of the infective capacity over macrophages of drug-resistant Mycobacterium tuberculosis and evaluation of the synergic activity of different drug combinations.

  •   LASID fellowship award

    Latin American Society for Immunodeficiencies

    México, 2020

    The Latin American Society of Primary Immunodeficiency LASID is an association of professionals dedicated to develop and perfect education, scientific research and health care within the field of Inborn Errors of Immunity (IEI). Scholarship Program Fellowship Award, which offers an award to an individual for training during two years in the field of primary immunodeficiency diseases.


 

Article (25)

Refractory systemic juvenile idiopathic arthritis successfully treated with rapamycin.
Contribution of NKT cells to the immune response and pathogenesis triggered by respiratory viruses
TCR Repertoire Characterization for T Cells Expanded in Response to hRSV Infection in Mice Immunized with a Recombinant BCG Vaccine
High-efficiency nuclear transformation of the microalgae Nannochloropsis oceanica using Tn5 Transposome for the generation of altered lipid accumulation phenotypes
Assessing the Importance of Domestic Vaccine Manufacturing Centers=> An Overview of Immunization Programs, Vaccine Manufacture, and Distribution.
Insights on the crosstalk between dendritic cells and helper T cells in novel genetic etiology for mendelian susceptible mycobacterial disease
Insights on the crosstalk between dendritic cells and helper T cells in novel genetic etiology for mendelian susceptible mycobacterial disease.
Patterns of antibody response during natural hRSV infection=> insights for the development of new antibody-based therapies.
Recombinant BCG Vaccines Reduce Pneumovirus-Caused Airway Pathology by Inducing Protective Humoral Immunity
Recombinant BCG Vaccines Reduce Pneumovirus-Caused Airway Pathology by Inducing Protective Humoral Immunity.
A safe and efficient BCG vectored vaccine to prevent the disease caused by the human Respiratory Syncytial Virus.
A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice.
Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia-Implications for Vaccine Design.
Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors=> A Synergic Inhibition of Both Innate and Adaptive Immunity
Human Respiratory Syncytial Virus=> Infection and Pathology.
In vitro time-kill curves study of three antituberculous combinations against Mycobacterium tuberculosis clinical isolates
In vitro time-kill curves study of three antituberculous combinations against Mycobacterium tuberculosis clinical isolates
Contribution of autophagy to antiviral immunity.
Activity and interactions of levofloxacin, linezolid, ethambutol and amikacin in three-drug combinations against Mycobacterium tuberculosis isolates in a human macrophage model
Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array
In vitro effect of three-drug combinations of antituberculous agents against multidrug-resistant Mycobacterium tuberculosis isolates
Synergistic effect of two combinations of antituberculous drugs against Mycobacterium tuberculosis
Impaired fitness of Mycobacterium tuberculosis resistant isolates in a cell culture model of murine macrophages
Characterization of mutations in streptomycin-resistant Mycobacterium tuberculosis clinical isolates in the area of Barcelona
Tuberculosis transmission patterns among Spanish-born and foreign-born populations in the city of Barcelona

ConferencePoster (16)

Antibodies Secretion Promoted by a Recombinant BCG Strain Induces a Protective Immune Response Against Human Respiratory Viruses
Contribution of CD1d to immune responses and pathogenesis in mouse models of human respiratory syncytial virus and the human metapneumovirus infections.
Phase I clinical trial for a recombinant BCG expressing the nucleoprotein of the human respiratory syncytial virus (hRSV) in healthy adults
Role of CD1d receptor in the pathology caused by the human respiratory syncytial virus and the human metapneumovirus
Contribution of Natural Killer T cells to the pathology caused by the Respiratory Syncytial Virus and the Metapneumovirus
Contribution of Natural Killer T cells to the pathology caused by the Respiratory Syncytial Virus and the Metapneumovirus.
A single, low dose of a current Good Manufacturing Practive (cGMP) recombinant BCG vaccine confers protection against human respiratory syncytial virus (hRSV) infection and lung pathology in mice
Synergism of linezolid, levofloxacin and amikacin combination against multidrug-resistant and drug-susceptible isolates of M. tuberculosis
Caracterización, diagnóstico y estudio de la capacidad de infección de aislados de Mycobacterium tuberculosis resistentes a los fármacos
Intracellular penetration capacity of Mycobacterium tuberculosis drug-resistant isolates using a murine macrophage model. Intracellular penetration capacity of Mycobacterium tuberculosis drug-resistant isolates using a murine macrophage model
Synergistic activity of three antituberculous drug combinations against clinical isolates of Mycobacterium tuberculosis resistant to different drugs.
Análisis epidemiológico de los mecanismos moleculares más frecuentemente implicados en la resistencia al etambutol y su relación con la multirresistencia en Mycobacterium tuberculosis
Estudio de la capacidad infectiva sobre macrófagos de aislados clínicos de Mycobacterium tuberculosis resistentes a los fármacos de primera línea y evaluación de la actividad sinérgica de diversas combinaciones de fármacos
Synergistic activity of two antituberculous drug combinations against clinical isolates of Mycobacterium tuberculosis resistant to isoniazid
Comparison of four colour IS6110-fAFLP with the classic IS6110 RFLP on the ability to detect recent transmission in the city of Barcelona, Spain
High frequency of embB codon 406 mutations in ethambutol-resistant isolates of Mycobacterium tuberculosis

Proyecto (6)

Clinical trial of safety, tolerability and immunogenicity of a recombinant vaccine against respiratory syncytial virus
CHARACTERIZATION AND FUNCTIONAL RELEVANCE OF THE T CELL RECEPTOR REPERTOIRE OF HRSV-SPECIFIC T CELLS EXPANDED IN RESPONSE TO HRSV INFECTION IN NAIVE AND VACCINATED MICE.
ELUCIDATING THE MECHANISMS OF PATHOGENICITY USED BY THE HUMAN RESPIRATORY SYNCYTIAL VIRUS TO PREVENT T CELL ACTIVATION AND CAUSE CENTRAL NERVOUS SYSTEM INFLAMMATION.
Estudio de la actividad sinérgica de combinaciones de fármacos antituberculosos frente a aislados clínicos de M.tuberculosis multirresistentes utilizando un modelo in vitro y un modelo ex-vivo con macrófagos humanos.
Detección rápida de la resistencia a los fármacos de primera línea en Mycobacterium tuberculosis mediante chips de DNA de baja densidad. Estudio in vitro de la infectividad en macrófagos humanos de los genotipos resistentes más relevantes.
Eficacia in vitro del tratamiento antibiótico frente a cepas resistentes de Mycobacterium tuberculosis. Estudio de la capacidad infectiva sobre macrófagos y evaluación de la actividad sinérgica de diversas combinaciones de fármacos

Review (3)

Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution
Patterns of antibody response during natural hRSV infection: insights for the development of new antibody-based therapies
Human Respiratory Syncytial Virus: Infection and Pathology
32
Emma Rey

Professor/Researcher

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

1
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

1
Luz Vásquez

Profesor Asociado

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Karen Fuenzalida

Investigador responsable de la Unidad de investigación y desarrollo del Laboratorio de Enfermedades Metabólicas, área de laboratorio.

Instituto de Nutrición y Tecnología de Alimentos

Universidad de Chile

Santiago, Chile

1
Héctor Osorio

Postdoctorado

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Felipe Tapia

Director de Proyectos

Ingeniería de Bioprocesos

Profesional Independiente

Puerto Montt, Chile

1
Nicolás Gálvez

Asistente de Investigación

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Leandro Carreño

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

1
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Christian Palavecino

Profesor asistente

Universidad Central de Chile

Santiago, Chile

1
Margarita Lay

PROFESOR ASISTENTE

BIOTECNOLOGÍA

UNIVERSIDAD DE ANTOFAGASTA

ANTOFAGASTA, Chile