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RICARDO ADOLFO CASTRO LOPEZ

Jefe de unidad

Pontificia Universidad Católica de Chile

Santiago, Chile

Outcomes clínicos del paciente crítico Shock séptico

Public Health, UNIVERSITY OF PITTSBURGH. Estados Unidos, 2011
Medico Cirujano, UNIVERSIDAD DE CONCEPCION. Chile, 1995

Profesor Asistente Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Santiago, Chile

2006 - At present


Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock The ANDROMEDA-SHOCK Randomized Clinical Trial Hernandez, G; Ospina-Tascon, GA; Damiani, LP; Estenssoro, E; Dubin, A; Hurtado, J; Friedman, G; Castro, R; Alegria, L; Teboul, JL; Cecconi, M; Ferri, G; Jibaja, M; Pairumani, R; Fernandez, P; Barahona, D; Granda-Luna, V; Cavalcanti, AB; Bakker, J Article JAMA - Journal of the American Medical Association (2019)
The man from room number seven. Hernández, Glenn; Llewelyn, Eyleen; Castro, Ricardo Article Intensive care medicine (2019)
Early goal-directed therapy using a physiological holistic view=> the ANDROMEDA-SHOCK-a randomized controlled trial Hernandez, G; Cavalcanti, AB; Ospina-Tascon, G; Zampieri, FG; Dubin, A; Hurtado, FJ; Friedman, G; Castro, R; Alegria, L; Cecconi, M; Teboul, JL; Bakker, J Article ANNALS OF INTENSIVE CARE (2018)
Early goal-directed therapy using a physiological holistic view=> the ANDROMEDA-SHOCK-a randomized controlled trial. Hernández, Glenn; Cavalcanti, Alexandre Biasi; Ospina-Tascón, Gustavo; Zampieri, Fernando Godinho; Dubin, Arnaldo; Hurtado, F Javier; Friedman, Gilberto; Castro, Ricardo; Alegría, Leyla; Cecconi, Maurizio; Teboul, Jean-Louis; Bakker, Jan Article Annals of intensive care (2018)
The practice of intensive care in Latin America=> a survey of academic intensivists Castro, R; Nin N., Rios; F, Alegria; L, Estenssoro; E, Murias; G, Friedman; G, Jibaja; M, Ospina-Tascon; G, Hurtado; J, Marin; MD, Machado; FR, Cavalcanti; AB, Dubin; A, Azevedo; L, Cecconi; M, Bakker; J, Hernandez Article CRITICAL CARE (2018)
A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients=> a proof-of-concept study. Alegría, Leyla; Vera, Magdalena; Dreyse, Jorge; Castro, Ricardo; Carpio, David; Henriquez, Carolina; Gajardo, Daniela; Bravo, Sebastian; Araneda, Felipe; Kattan, Eduardo; Torres, Pedro; Ospina-Tascón, Gustavo; Teboul, Jean-Louis; Bakker, Jan; Hernández, Glenn Article Annals of intensive care (2017)
Capillary refill time during fluid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality. Lara, Barbara; Enberg, Luis; Ortega, Marcos; Leon, Paula; Kripper, Cristobal; Aguilera, Pablo; Kattan, Eduardo; Castro, Ricardo; Bakker, Jan; Hernandez, Glenn Article PloS one (2017)
Organizational Issues, Structure, and Processes of Care in 257 ICUs in Latin America=> A Study From the Latin America Intensive Care Network. Estenssoro, Elisa; Alegría, Leyla; Murias, Gastón; Friedman, Gilberto; Castro, Ricardo; Nin Vaeza, Nicolas; Loudet, Cecilia; Bruhn, Alejandro; Jibaja, Manuel; Ospina-Tascon, Gustavo; Ríos, Fernando; Machado, Flavia R; Biasi Cavalcanti, Alexandre; Dubin, Arnaldo; Hurtado, F Javier; Briva, Arturo; Romero, Carlos; Bugedo, Guillermo; Bakker, Jan; Cecconi, Maurizio; Azevedo, Luciano; Hernandez, Glenn Article Critical care medicine (2017)
[The impact of a better coordination between emergency and intensive care units in the care of critically ill patients]. Lara, Bárbara A; Cataldo, Alejandro; Castro, Ricardo; Aguilera, Pablo R; Ruiz, Carolina; Andresen, Max Article Revista medica de Chile (2016)
Characteristics and evolution of patients admitted to a public hospital intensive care unit Ruiz, C; Diaz, MA; Zapata, JM; Bravo, S; Panay, S; Escobar, C; Godoy, J; Andresen, M; Castro, R Article REVISTA MEDICA DE CHILE (2016)
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock. Hernández, Glenn; Tapia, Pablo; Alegría, Leyla; Soto, Dagoberto; Luengo, Cecilia; Gomez, Jussara; Jarufe, Nicolas; Achurra, Pablo; Rebolledo, Rolando; Bruhn, Alejandro; Castro, Ricardo; Kattan, Eduardo; Ospina-Tascón, Gustavo; Bakker, Jan Article Critical care (London, England) (2016)
The impact of a better coordination between emergency and intensive care units in the care of critically ill patients Lara BA; Cataldo A.; Castro R.; Aguilera PR; Ruiz C.; Andresen M. Article ISI REVISTA MEDICA DE CHILE (2016)
What is the role of corticosteroids in the management of sepsis? Jerez, J; Castro R. Article ISI Medwave (2016)
What is the role of recombinant activated protein C in the management of sepsis? Alvarado J.; Castro R. Article ISI Medwave (2016)
Posttraumatic stress disorder symptoms in close relatives of intensive care unit patients: Prevalence data resemble that of earthquake survivors in Chile Andresen M.; Guic, E; Orellana, A; Diaz, MJ; Castro R. Article ISI SCOPUS Journal of Critical Care (2015)
Management of the potential organ donor Bugedo G.; Bravo S.; Romero C.; Castro R. Article ISI REVISTA MEDICA DE CHILE (2014)
When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring Hernández G.; Luengo C.; Bruhn A.; Kattan E.; Friedman, G; Ospina-Tascon, GA; Fuentealba, A.; Castro R.; Regueira T.; Romero C.; Ince C.; Bakker, J Article ISI SCOPUS ANNALS OF INTENSIVE CARE (2014)
Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study Hernández G.; Bruhn A.; Luengo C.; Regueira T.; Kattan E.; Fuentealba, A.; Florez, J; Castro R.; Aquevedo, A; Pairumani R.; Mcnab P.; Ince C. Article ISI SCOPUS Intensive Care Medicine (2013)
Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients Hernández G.; Boerma, EC; Dubin, A; Bruhn A.; Koopmans, M; Edul, VK; Ruiz C.; Castro R.; Pozo, MO; Pedreros C; Veas E; Fuentealba, A.; Kattan E.; Rovegno M.; Ince C. Article ISI SCOPUS Journal of Critical Care (2013)
Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study Hernández G.; Pedreros C; Veas E; Bruhn A.; Romero C.; Rovegno M.; Neira, R; Bravo S.; Castro R.; Kattan E.; Ince C. Article ISI SCOPUS Journal of Critical Care (2012)
Light and the outcome of the critically ill: an observational cohort study Castro, R.A.; Angus D.C.; Hong S.Y.; Lee C.; Weissfeld L.A.; Clermont G; Rosengart M.R. Article ISI SCOPUS Critical Care (2012)
Natriuretic peptide type-B can be a marker of reperfusion in patients with pulmonary thromboembolism subjected to invasive treatment Andresen M.; González A; Mercado M.; Díaz O.; Meneses L.; Fava, M; Cordova S; Castro R. Article ISI SCOPUS International Journal of Cardiovascular Imaging (2012)
Persistent sepsis-induced hypotension without hyperlactatemia: A distinct clinical and physiological profile within the spectrum of septic shock Hernández G.; Bruhn A.; Castro R.; Pedreros C; Rovegno M.; Kattan E.; Veas E; Fuentealba, A.; Regueira T.; Ruiz C.; Ince C. Article SCOPUS Critical Care Research and Practice (2012)
Relationship of systemic, hepatosplanchnic, and microcirculatory perfusion parameters with 6-hour lactate clearance in hyperdynamic septic shock patients: an acute, clinical-physiological, pilot study Hernández G.; Regueira T.; Bruhn A.; Castro R.; Rovegno M.; Fuentealba, A.; Veas E; Berrutti, D; Florez, J; Kattan E.; Martin, C; Ince C. Article ISI SCOPUS Annals of Intensive Care (2012)
Persistent sepsis-induced hypotension without hyperlactatemia: Is it really septic shock? Hernández G.; Castro R.; Romero C.; De la Hoz, C.; Angulo, D; Aranguiz I.; Larrondo, J; Bujes, A; Bruhn A. Article ISI SCOPUS Journal of Critical Care (2011)
The effect of light on critical illness Castro R.; Angus, DC; Rosengart MR Article ISI CRITICAL CARE (2011)
Diagnostic yield of CT pulmonary angiography and venography for thromboembolic disease Andresen M.; González A; Díaz O.; Meneses L.; Fava, M; Orlandini E.; Clede L.; Regueira T.; Castro R. Article ISI REVISTA MEDICA DE CHILE (2010)
Diagnostic yield of CT pulmonary angiography and venography for thromboembolic disease Evaluación prospectiva de la venografía mediante angio TC en el diagnóstico de enfermedad tromboembólica Max Andresen H; Orlando Díaz P.; Tomas Regueira H.; Castro R.; González A; Meneses L.; Fava, M; Orlandinia E.; Cledea L. Article SCOPUS Revista Medica de Chile (2010)
Evaluación prospectiva de la venografía mediante angioTC en el diagnóstico de enfermedad tromboembólica ADRESEN H, MAX; González, Alejandro; Díaz P, Orlando; Meneses, Luis; Fava, Mario; Orlandini, Elisa; CLEDE, LETICIA; REGUEIRA H, TOMAS; Castro, Ricardo Article SCIELO REVISTA MEDICA DE CHILE (2010)
Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study Hernández G.; Pena, H; Cornejo R.; Rovegno M.; Retamal J.; Navarro, JL; Aranguiz I.; Castro R.; Bruhn A. Article ISI SCOPUS CRITICAL CARE (2009)
An evidence-based resuscitation algorithm applied from the emergency room to the ICU improves survival of severe septic shock Castro R.; Regueira T.; Aguirre, ML; Llanos, OP; Bruhn A.; Bugedo G.; Dougnac, A; Castillo L.; Andresen M.; Hernández G. Article ISI SCOPUS MINERVA ANESTESIOLOGICA (2008)
Intra-abdominal hypertension: Incidence and association with organ dysfunction during early septic shock Regueira T.; Bruhn A.; Hasbún P.; Aguirre, M; Romero C.; Llanos, O.; Castro R.; Bugedo G.; Hernández G. Article ISI SCOPUS JOURNAL OF CRITICAL CARE (2008)
Pro- and anti-inflammatory balance of septic patients is associated with severity and outcome Dougnac, A; Castro R.; Regueira T.; Mercado M.; Andresen M.; Riquelme A.; Calvo M.; Eugenin, E; Arellano M.; Pattillo, A Article SCOPUS ?Critical Care and Shock (2007)
High-volume hemofiltration as salvage therapy in severe hyperdynamic septic shock Cornejo R.; Downey P.; Castro R.; Romero C.; Regueira T.; Vega, J; Castillo L.; Andresen M.; Dougnac, A; Bugedo G.; Hernández G. Article ISI SCOPUS INTENSIVE CARE MEDICINE (2006)


RELATIONSHIP OF SYSTEMIC, HEPATOSPLANCHNIC AND MICROCIRCULATORY PERFUSION PARAMETERS WITH SIX-HOUR LACTATE CLEARANCE IN HYPERDYNAMIC SEPTIC SHOCK PATIENTS: AN ACUTE CLINICAL-PHYSIOLOGICAL PILOT STUDY Hernández G.; Regueira T.; Bruhn A.; Castro R.; Rovegno M.; Fuentealba, A.; Veas E; Kattan E.; Martin, C; Berrutti, D; Ince C. Abstract ISI INTENSIVE CARE MEDICINE (2012)
EFFECTS OF DOBUTAMINE ON MICROCIRCULATION, REGIONAL AND PERIPHERAL PERFUSION IN SEPTIC SHOCK PATIENTS: A RANDOMIZED DOUBLE BLIND CROSSOVER TRIAL. PRELIMINARY REPORT Hernández G.; Regueira T.; Bruhn A.; Pedreros C; Ruiz C.; Veas E; ramirez, j; Martin, C; Bugedo G.; Mcnab P.; Castro R.; Zapata, M; Ince C. Abstract ISI INTENSIVE CARE MEDICINE (2011)
THE RELATIONSHIP BETWEEN MICROCIRCULATORY FLOW ABNORMALITIES AND SYSTEMIC HEMODYNAMIC VARIABLES IN SEPTIC SHOCK PATIENTS. A MULTICENTRE CROSS-SECTIONAL STUDY Hernández G.; Boerma, EC; Dubin, A; Pedreros C; Bruhn A.; Koopmans, M; Pozo M.; Edul, VK; Ruiz C.; Kattan E.; Castro R.; Rovegno M.; Ince C. Abstract ISI INTENSIVE CARE MEDICINE (2011)
EARLY NORMALIZATION OF CENTRAL VENOUS O-2 SATURATION AFTER EMERGENCY INTUBATION IN SEPTIC PATIENTS DOES NOT ASSURE AN IMPROVEMENT IN GLOBAL DYSOXIA Hernández G.; Pena, H; Cornejo R.; Castro R.; Retamal J.; Rovegno M.; Aranguiz I.; Angulo, D; Bujes, A; Pérez, C.; Bruhn A. Abstract ISI INTENSIVE CARE MEDICINE (2009)
SEPTIC SHOCK: HETEROGENEOUS DISEASE OR INAPPROPRIATE DEFINITIONS Hernández G.; Castro R.; Bruhn A.; Larrondo, FJ; De la Hoz, C.; Bujes, A; Aranguiz I.; Angulo, D; Bravo S.; Diaz, MA; ramirez, j Abstract ISI INTENSIVE CARE MEDICINE (2009)
High frequency of cholestatic variant in Chilean patients with autoimmune hepatitis Alvarez, MM; Vial, P.; Castro R.; Arrese MA; Gonzalez, RG; Soza, JA; González A; Duarte, I; Glasinovic, JC Abstract ISI GASTROENTEROLOGY (2001)


I wished she had meningoencephalitis Castro R. EditorialMaterial ISI INTENSIVE CARE MEDICINE (2014)


Immediate cardiac arrest resuscitation skills are acquired in 8th grade students during normal class hours with a low-cost, short-term, self-instruction video Andresen M.; Castro R.; Hasbún P.; Rojas, L.; Sarfatis A; Riquelme A. Letter ISI SCOPUS Resuscitation (2012)
Reply to letter: Teaching and outcomes standards in community-based CPR training programs: Walking one step at a time Castro R.; Hasbún P.; Rojas, L.; Sarfatis A; Riquelme A.; Andresen M. Letter ISI SCOPUS Resuscitation (2012)


Código lila=> hacia la humanización del cuidado al final de la vida del paciente crítico y su familia. Vicerrectoría de Investigación Pontifica Universidad Católica de Chile (9366/DPCC201) Proyecto 2018-2019 Inv. Principal
PRactice of VENTilation in Critically Ill Patients without ARDS (PRoVENT) – an International Observational Study Estudio observacional SIN financiamiento (Clinicaltrials.gov identifier=> NCT 01868321) Proyecto 2013-2014 Coinvestigador(a)


The holistic view on perfusion monitoring in septic shock Hernández G.; Bruhn A.; Castro R.; Regueira T. Review ISI SCOPUS Current Opinion in Critical Care (2012)