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Marjorie Valeria Cepeda Plaza

Profesor asistente

Universidad Andrés Bello

Santiago, Chile

Química bioinorgánica, DNAzimas, mecanismos de reacción y estrategias catalíticas

Química, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009
Químico, UNIVERSIDAD DE CHILE. Chile, 2006

Profesor Asociada Full Time

Universidad Andrés Bello

Ciencias Exactas

Santiago, Chile

2014 - At present

Profesora Asociada Full Time

Universidad Andrés Bello

Santiago, Chile

2014 - At present

“EFECTO DEL LIGANTE EN LAS PROPIEDADES FOTOFÍSICAS DE COMPLEJOS TRICARBONIL RENIO(I)”
Eliseo Valdes, Unidad de Investigación, Co-tutora tesis pregrado, Licenciatura en Química, Departamento Ciencias Químicas, Universidad Andrés Bello. 2016.

“PURIFICACIÓN Y CARACTERIZACIÓN FOTOFÍSICA DEL COMPLEJO [(PHEN)RE(CO)3(ETHINYL-PY)]+: PREPARANDO LAS BASES PARA EL DESARROLLO DE APLICACIONES BIOLÓGICAS” Sergio Sánchez Guajardo, Unidad de Investigación, Tutora, tesis pregrado, Licenciatura en Química. Departamento Ciencias Químicas, Universidad Andrés Bello. 2016.

"ESTUDIO DE CONJUGACIÓN DE APTÁMERO A DOS SISTEMAS DE NANOPARTÍCULAS Y EVALUACIÓN DE INTERNALIZACIÓN CELULAR" Andrea Constanza Ortiz Orrego, Co-tutora tesis pregrado, Química y Farmacia, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. 2018.

“EVALUACIÓN DE LA PARTICIPACIÓN DE Mg2+ EN EL MECANISMO DE CATÁLISIS DE LA DNAZIMA 8-17” Francisca Rojas Hernández, Unidad de Investigación, Tutora, tesis pregrado, Licenciatura en Química. Departamento Ciencias Químicas, Universidad Andrés Bello. 2020.


Exploring the catalytic mechanism of the 10-23 DNAzyme: insights from pH-rate profiles Parra-Meneses, Virginia; Silva-Galleguillos, Victoria; Cepeda-Plaza, Marjorie Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2024)
Synthesis, Physicochemical Characterization, and Antimicrobial Evaluation of Halogen-Substituted Non-Metal Pyridine Schiff Bases Carreno, Alexander; Morales-Guevara, Rosaly; Cepeda-Plaza, Marjorie; Paez-Hernandez, Dayan; Preite, M.; Polanco, Ruben; Barrera, Boris; Fuentes, Ignacio; Marchant, Pedro; Fuentes, Juan A. Article ISI SCOPUS MOLECULES (2024)
The role of Na+ in catalysis by the 8-17 DNAzyme Article ORGANIC & BIOMOLECULAR CHEMISTRY (2022)
The role of Na<SUP>+</SUP> in catalysis by the 8-17 DNAzyme Parra-Meneses, Virginia; Rojas-Hernandez, Francisca; Cepeda-Plaza, Marjorie Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2022)
Aptamer-functionalized lipid-core micelles loaded with rhenium tricarbonyl complex Ortiz, Andrea C.; Casas, Islavo; Naranjo, Omar; Pizarro, Nancy; Garcia, Lorena Article ISI POLYHEDRON (2021)
Hydrated metal ion as a general acid in the catalytic mechanism of the 8-17 DNAzyme Cortes-Guajardo, Catalina; Rojas-Hernandez, Francisca; Paillao-Bustos, Romina Article ISI ORGANIC & BIOMOLECULAR CHEMISTRY (2021)
An amine linker group modulates luminescent properties in a Rhenium(I) tricarbonyl complex. How can it be applied for ratiometric oxygen sensing? Article ISI SCOPUS (2020)
Evidence of a General Acid-Base Catalysis Mechanism in the 8-17 DNAzyme McGhee, Claire E.; Lu, Yi Article ISI SCOPUS BIOCHEMISTRY (2018)
Solvent, coordination and hydrogen-bond effects on the chromic luminescence of the cationic complex [(phen)(H2O)Re(CO)(3)] Mella, Pablo; Cabezas, Karina; Cepeda-Plaza, Marjorie; G?nther, German; Vega, Andr?s Article ISI SCOPUS NEW JOURNAL OF CHEMISTRY (2016)
Tuning the photophysical properties of a (P,N)Re-I complex by adding a -NH- fragment into a P,N-bidentate ligand: The case of [P,N{(C6H5)(2)(C5H4N)NHPRe(CO)(3)Br] Mella P.; Palma J.C.; Aguirre, P.; Manzur, J.; Pizarro N.; Vega A. Article ISI SCOPUS POLYHEDRON (2016)
Clean Singlet Oxygen Production by a ReI Complex Embedded into a Flexible/Self-Standing Polymeric Silsesquioxane Film Spada, Ramiro M., Cepeda-Plaza, Marjorie, Gomez, Maria L., Günther, German, Jaque, Pablo, Pizarro Urzúa, Nancy, Palacios, Rodrigo E., and Vega, Andres Article The Journal of Physical Chemistry C (2015)
Dual Emission of a Novel (P,N) Re-I Complex: A Computational and Experimental Study on [P,N-{(C6H5)(2)(C5H4N)P}Re(CO)(3)Br] Pizarro N.; Duque, M.; Charnorro, E; Nonell, S; Manzur, J.; De la Fuente, JR; Gunther, G.; Cepeda-Plaza, M; Vega A. Article ISI SCOPUS Journal of Physical Chemistry A (2015)
gamma-Cyclodextrin modulates the chemical reactivity by multiple complexation Fernandez-Rosas, J; Pessego, M; Cepeda-Plaza, M; Basilio, N; Parajo, M; Rodriguez-Dafonte, P; Garcia-Rio, L Article ISI SCOPUS ORGANIC AND BIOMOLECULAR CHEMISTRY (2015)
Structural and photophysical properties of [(CO)(3)(phen) Re(mu-Br)Re(phen)(CO)(3)](+)[(CO)(3)(+)[Re(mu-Br)(3)Re(CO)(3)](-): Where does its luminescence come from? Gallardo H.; Cepeda-Plaza, M; Nonell, S; Gunther, G.; Chamorro, E.; Pizarro N.; Vega A. Article ISI SCOPUS POLYHEDRON (2015)
Macrocyclic ZnII and CuII complexes as guests of the hybrid composites based on the layered MnPS3 phase. Comparison of spectroscopic properties Fuentelaba, P; Seron, L.; Sánchez C; Manzur, J.; Paredes-Garcia, V; Pizarro N.; Cepeda M.; Venegas-Yazigi, D; Spodine, E. Article ISI SCOPUS JOURNAL OF COORDINATION CHEMISTRY (2014)
Competition between surfactant micellization and complexation by cyclodextrin Cepeda M.; Davina, R; Garcia-Rio, L; Parajo, M; Rodriguez-Dafonte, P; Pessego, M Article ISI SCOPUS ORGANIC AND BIOMOLECULAR CHEMISTRY (2013)
Kinetic and theoretical study on nucleofugality in the phenolysis of 3-nitrophenyl and 4-nitrophenyl 4-cyanophenyl thionocarbonates Castro, EA; Cañete Á.; Campodonico, PR; Cepeda M.; Pavez P.; Contreras R. Article ISI SCOPUS Chemical Physics Letters (2013)
Metal ion as both a cofactor and a probe of metal-binding sites in a uranyl-specific DNAzyme: a uranyl photocleavage study Null, Eric L. Article ISI NUCLEIC ACIDS RESEARCH (2013)
Phenolysis and Aminolysis of 4-Nitrophenyl and 2,4-Dinitrophenyl S-Methyl Thiocarbonates in Aqueous Ethanol Castro, EA; Cepeda M. Article ISI SCOPUS International Journal of Chemical Kinetics (2011)
Cyclodextrin-surfactant binding constant as driven force for uncomplexed cyclodextrin in equilibrium with micellar systems Cepeda M.; Davina, R; Garcia-Rio, L; Parajo, M Article ISI CHEMICAL PHYSICS LETTERS (2010)
Experimental and Theoretical Studies on the Nucleofugality Patterns in the Aminolysis and Phenolysis of S-Aryl O-Aryl Thiocarbonates Castro, EA; Aliaga M.; Campodonico, PR; Cepeda M.; Contreras R. Article ISI SCOPUS Journal of Organic Chemistry (2009)
Phenolysis of diaryl thiolcarbonates and thionocarbonates Castro, EA; Cepeda M.; Pavez P. Article ISI JOURNAL OF PHYSICAL ORGANIC CHEMISTRY (2009)


Understading the Bases of DNA Catalysis=> Machanisms of Reaction Involved in RNA-Cleaving by the 8-17 DNAzyme. FONDECYT (1181438) Proyecto 2018-2021 Inv. Principal
Understanding the Bases of DNA Catalysis: Mechanisms of Reaction Involved in RNA-cleaving by the 8-17 DNAzyme Marjorie Cepeda Plaza Proyecto (2018)
POTENTIAL USES OF RHENIUM COMPLEXES AS PHOTOSENSITIZERS, BACTERICIDES OR MOLECULAR PROBES: A PHOTOPHYSICAL AND PHOTOCHEMICAL STUDY Nancy Pizarro Urzúa; Marjorie Cepeda Plaza Proyecto (2016)
POTENTIAL USES OF RHENIUM COMPLEXES AS PHOTOSENSITIZERS, BACTERICIDES OR MOLECULAR PROBES=> A PHOTOPHYSICAL AND PHOTOCHEMICAL STUDY FONDECYT (1160749) Proyecto 2016-2020 Coinvestigador(a)
Estudios Fisicoquímicos, Fotofísicos y de Mecanismos de Reacción de ADNs Catalíticos. Marjorie Cepeda Plaza Proyecto (2014)
LUMINESCENT BIO-FUNTIONALIZED RHENIUM COMPLEXES FOR IMAGING AND THERAPY APPLICATIONS. Marjorie Cepeda Plaza Proyecto (2014)
LUMINESCENT BIO-FUNTIONALIZED RHENIUM COMPLEXES FOR IMAGING AND THERAPY APPLICATIONS. FONDECYT (11140401) Proyecto 2014-2017 Inv. Responsable
Proyecto de Inserción en la Academia 2013. Estudios Fisicoquímicos, Fotofísicos y de Mecanismos de Reacción de ADNs Catalíticos PAI (79130030) Proyecto 2014-2016 Inv. Principal
PHOTOPHYSICAL AND PHOTOCHEMICAL STUDY OF NEW ANTIHYPERTENSIVE DRUGS IN HOMOGENEOUS AND MICROHETEROGENEOUS SYSTEMS. FONDECYT (1110866) Proyecto 2011-2015 Personal técnico y/o de apoyo
ESTUDIO DEL COMPORTAMIENTO FOTOFISICO Y FOTOQUIMICO DE NUEVOS COLORANTES FLUORESCENTES=> ARILOXAZINONAS Y ARILOXAZOLES SUSTITUIDOS. FONDECYT (1050796) Proyecto 2005-2008 Personal técnico y/o de apoyo
FOTOQUIMICA Y FOTOFISICA DE COMPUESTOS DERIVADOS DE LA QUINOLINA , UNA CONTRIBUCION PARA ENTENDER LA ACTIVIDAD FOTOSENSIBILIZADORA DE LAS DROGAS ANTIMALARICAS FONDECYT (1011027) Proyecto 2001-2005 Tesista


A guide to RNA structure analysis and RNA-targeting methods Aguilar, Rodrigo; Mardones, Constanza Review ISI FEBS JOURNAL (2024)
Insights into DNA catalysis from structural and functional studies of the 8-17 DNAzyme Peracchi A. Review ISI SCOPUS ORGANIC & BIOMOLECULAR CHEMISTRY (2020)