Man

Jenaro Garcia-Huidobro Prieto

Profesor Asistente

Universidad de Talca

Talca, Chile

Líneas de Investigación


Polyamines, genetic variability, personalized medicine and cancer

Educación

  •  Bioquímica, Universiad de Concepcion. Chile, 2006
  •  Bioquímico, UNIVERSIDAD DE CONCEPCION. Chile, 2008
  •  Bioquímica, UNIVERSIDAD DE CONCEPCION. Chile, 2008
  •  Biochemistry and Molecular and Cellular Biology, University of Arizona. Estados Unidos, 2014

Experiencia Académica

  •   Post-Doctoral Research Associate Full Time

    UNIVERSITY OF ARIZONA

    Arizona Cancer Center

    Tucson, Estados Unidos

    2014 - 2014

  •   Post-Doctoral Fellow Full Time

    UNIV TEXAS M.D. ANDERSON CANCER CENTER

    Translational Molecular Pathology

    Houston, Estados Unidos

    2014 - 2015

  •   Post-Doctoral Research Associate Full Time

    UNIVERSITY OF MIAMI

    Sylvester Comprehensive Cancer Center

    Miami, Estados Unidos

    2015 - 2018

  •   Research Associate Full Time

    UNIVERSITY OF MIAMI

    Sylvester Comprehensive Cancer Center

    Miami, Estados Unidos

    2018 - 2019


 

Article (6)

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

Chan, HL; Beckedorff, F; Zhang, YS; Garcia-Huidobro, J; Jiang, H; Colaprico, A; Bilbao, D; Figueroa, ME; LaCava, J; Shiekhattar, R; Morey, L

Article ISI SCOPUS
NATURE COMMUNICATIONS  (2018)

Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome

Filgueira, C. S.; Nicolov, E.; Hood, R. L.; Ballerini, A.; Garcia-Huidobro, J.; Lin, J. Z.; Fraga, D.; Webb, P.; Sabek, O. M.; Gaber, A. O.; Phillips, K. J.; Grattoni, A.

Article ISI
INTERNATIONAL JOURNAL OF OBESITY  (2016)

The Protease Degrading Sperm Histones Post-Fertilization in Sea Urchin Eggs Is a Nuclear Cathepsin L That Is Further Required for Embryo Development

Morin, V; Sanchez-Rubio A.; Aze A.; Iribarren C.; Fayet C.; Desdevises Y.; Garcia-Huidobro, J; Imschenetzky M.; Puchi, M; Geneviere A.-M.

Article ISI SCOPUS
PLOS ONE  (2012)

POLYAMINES IN CANCER

Paz, Edwin A.; Garcia-Huidobro, Jenaro; Ignatenko, Natalia A.; Makowski, GS

Article ISI
ADVANCES IN CLINICAL CHEMISTRY, VOL 54  (2011)

A New Nuclear Protease With Cathepsin L Properties Is Present in HeLa and Caco-2 Cells

Puchi, M; Garcia-Huidobro, J; Cordova, C; Aguilar R.; Dufey E.; Imschenetzky M.; Bustos, P; Morin, V

Article ISI SCOPUS
Journal of Cellular Biochemistry  (2010)

Cathepsin L inhibitor I blocks mitotic chromosomes decondensation during cleavage cell cycles of sea urchin embryos

Morin, V; Sanchez A.; Quinones, K; Huidobro, JG; Iribarren C.; Bustos, P; Puchi, M; Geneviere, AM; Imschenetzky M.

Article ISI SCOPUS
JOURNAL OF CELLULAR PHYSIOLOGY  (2008)

Patent (2)

Carcinoma diagnosis and treatment based on ODC1 genotype

Garcia-Huidobro, Jenaro

Patent
 (2020)

Predictive markers for polyamine inhibitor cancer therapies

Garcia-Huidobro, Jenaro

Patent
 (2018)

Proyecto (9)

ENHANCER RNA THERAPY

National Institutes of Health (NIH) (1DP1CA228041-01)

Proyecto
2017-2022
Postdoctorado

A TUNABLE DELIVERY PLATFORM FOR IN VIVO INVESTIGATION OF THERAPEUTICS

National Institutes of Health (NIH) (1R21GM111544-01)

Proyecto
2014-2017
Postdoctorado

NON-CODING RNAS IN TRANSCRIPTION AND CHROMATIN ARCHITECTURE

National Institutes of Health (NIH) (5R01GM105754-05)

Proyecto
2014-2019
Postdoctorado

GENETIC VARIABILITY AS PROGNOSTIC OR PREDICTIVE FACTORS IN COLORECTAL EPITHELIAL TISSUE IN RISK OF COLORECTAL CANCER

National Institutes of Health (NIH) (3P50CA095060-10S2)

Proyecto
2011-2015
Tesista

PLEIOTROPIC FUNCTIONS OF FOXC2 IN EMT, STEM CELLS AND BREAST CANCER PROGRESSION

National Institutes of Health (NIH) (1R01CA155243-01)

Proyecto
2011-2016
Postdoctorado

ELUCIDATION OF INTEGRATOR'S FUNCTION

National Institutes of Health (NIH) (5R01GM078455-08)

Proyecto
2010-2018
Postdoctorado

PREVENTION OF APC-DEPENDENT INTESTINAL CARCINOGENESIS

National Institutes of Health (NIH) (5R01CA123065-05)

Proyecto
2010-2014
Tesista

ROL DE LA ESTRUCTURA DE LA CROMATINA DURANTE LA INICIACIÓN DE LA REPLICACIÓN POSTFECUNDACIÓN EN ERIZOS DE MAR

FONDECYT (C07B05)

Proyecto
2007-2010
Tesista

CISTEIN-PROTEASA QUE PARTICIPA EN REMODELACION DEL PRONUCLEO MASCULINO POSTFECUNDACION=> CONSOLIDACION DE UN MODELO Y PERSPECTIVAS FUTURAS.

FONDEF (1050100)

Proyecto
2005-2008
Tesista

8
Jenaro Garcia-Huidobro

Profesor Asistente

Universidad de Talca

Talca, Chile

3
Violeta Morin

Associate Research

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

2
Andrea Sanchez

Profesor Asociado

Bioquímica Clínica e Inmunología

UNIVERSIDAD DE CONCEPCION

concepcion, Chile

1
Rodrigo Aguilar

Assistant Professor

Institute for Biomedical Sciences

Universidad Andrés Bello

Santiago, Chile