Camilo Enrique Toledo Rivera


Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


  •  Ciencias Biomédicas, UNIVERSIDAD AUTONOMA DE CHILE. Chile, 2018
  •  Bioquimico, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2013

Experiencia Profesional

  •   Research assistant Full Time

    Centro de Estudios Científicos

    Valdivia, Chile

    2013 - 2015

Premios y Distinciones

  •   President Elect

    Nebraska Physiological Society

    Estados Unidos, 2017

    President Elect, Nebraska Physiological Society, 2017-2018

  •   Senior Editor

    The Journal of Physiology

    Estados Unidos, 2016

    Senior Editor, The Journal of Physiology, 2016-present

  •   Golden Heart Member

    American Heart Association

    Estados Unidos, 2016

    Golden Heart Member of American Heart Association, 2015-present

  •   UNMC Distinguished Scientist Award


    Estados Unidos, 2014

    UNMC Distinguished Scientist Award, 2014

  •   Chairman

    American Physiological Society

    Estados Unidos, 2012

    Chairman, Neural Control and Autonomic Regulation Section, American Physiological Society, 2012-2015

  •   Silver "U" Award


    Estados Unidos, 1999

    Silver "U" Award, Chancellor's Council, University of Nebraska Medical Center, Omaha, 1999

  •   Distinguished Basic Scientist Award


    Estados Unidos, 1993

    Joseph P. Gilmore, Ph.D. Distinguished Basic Scientist Award, University of Nebraska College of Medicine, Omaha, 1993


Article (38)

Cardiac diastolic and autonomic dysfunction are aggravated by central chemoreflex activation in heart failure with preserved ejection fraction rats
Carotid Body-Mediated Chemoreflex Drive in The Setting of low and High Output Heart Failure
Contribution of peripheral and central chemoreceptors to sympatho-excitation in heart failure
Epigenetic influences on carotid body function: a new snag in the road to treating sleep apnoea
Exercise training improves cardiac autonomic control, cardiac function, and arrhythmogenesis in rats with preserved-ejection fraction heart failure
KLF2 mediates enhanced chemoreflex sensitivity, disordered breathing and autonomic dysregulation in heart failure
The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
Exercise training normalizes renal blood flow responses to acute hypoxia in experimental heart failure: role of the α 1 -adrenergic receptor
Translational neurocardiology: preclinical models and cardioneural integrative aspects
Exercise training attenuates chemoreflex-mediated reductions of renal blood flow in heart failure
In adult female hamsters hypothyroidism stimulates D1 receptor-mediated breathing without altering D1 receptor expression
Mechanisms of carotid body chemoreflex dysfunction during heart failure
Modulation of angiotensin II signaling following exercise training in heart failure
Role of the Carotid Body Chemoreflex in the Pathophysiology of Heart Failure: A Perspective from Animal Studies
Selective carotid body ablation in experimental heart failure: a new therapeutic tool to improve cardiorespiratory control
Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure
Central role of carotid body chemoreceptors in disordered breathing and cardiorenal dysfunction in chronic heart failure
Hypothyroidism affects D2 receptor-mediated breathing without altering D2 receptor expression
Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide
Simvastatin Treatment Attenuates Increased Respiratory Variability and Apnea/Hypopnea Index in Rats With Chronic Heart Failure
The arterial chemoreflex and cardiac stress in heart failure: nothing to be sheepish about
Angiotensin Peptides and Nitric Oxide in Cardiovascular Disease
Carotid Chemoreceptor Ablation Improves Survival in Heart Failure
Inhibition of hydrogen sulfide restores normal breathing stability and improves autonomic control during experimental heart failure
Role of the Carotid Body in the Pathophysiology of Heart Failure
Be sympathetic to your nervous system
Effect of AT1 receptor blockade on intermittent hypoxia-induced endothelial dysfunction
Hypothyroidism stimulates D2 receptor-mediated breathing in response to acute hypoxia and alters D2 receptors levels in carotid bodies and brain
Neurohumoral Stimulation
Role of neurotransmitter gases in the control of the carotid body in heart failure
The Paradox of Carbon Monoxide and the Heart
Angiotensin and carotid body chemoreception in heart failure
Angiotensin-(1–7) increases neuronal potassium current via a nitric oxide-dependent mechanism
Hypothyroidism attenuates SCH 23390-mediated depression of breathing and decreases d1 receptor expression in carotid bodies, PVN and striatum of hamsters
Role of blood flow in carotid body chemoreflex function in heart failure
Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure
Expression of Neuronal Nitric Oxide Synthase in Rabbit Carotid Body Glomus Cells Regulates Large-Conductance Ca 2+ -Activated Potassium Currents
The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase

Abstract (5)

Enhanced carotid body chemoreflex function drives respiratory-sympathetic coupling in systolic heart failure
Enhanced Carotid Body-mediated Chemoreflex Drive in Heart Failure: a Matter of Flow
Reduced Carotid Body KLF2 Expression Contributes to Autonomic and Respiratory Dysfunction in Chronic Heart Failure
Calorie restriction as a new approach for resetting carotid body chemoreflex control in heart failure
Carotid body denervation reduces renal sympathetic nerve activity and fibrosis, and increases renal blood flow in congestive heart failure

EditorialMaterial (1)

Editorial: Carotid body: a new target for rescuing neural control of cardiorespiratory balance in disease

Letter (3)

Comment on "Precedence and autocracy in breathing control" [2]
Reply from Noah J. Marcus, Rodrigo Del Rio and Harold D. Schultz

Review (1)

Relevance of the Carotid Body Chemoreflex in the Progression of Heart Failure
Camilo Toledo



Pontificia Universidad Católica de Chile

Santiago, Chile

Rodrigo Del Rio

Assistant Professor


Pontificia Universidad Católica de Chile

Santiago, Chile

Claudia Lucero

Asistente Investigación-Docente

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

David Andrade

Associate Professor


Universidad de Antofagasta

Antofagasta, Chile

Hugo Diaz



Pontificia Universidad Católica de Chile

Santiago, Chile

Rodrigo Iturriaga

Chairman of the Department of Physiology



Santiago, Chile

Carlos Madrid


Centro I+D

Open World

Santiago, Chile