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Debora Alejandra Torrealba Sandoval

Investigador Postdoctoral

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

Líneas de Investigación


Inmunología en peces. Evaluación de eficacia de vacunas. Desarrollo de nanopartículas como inmunoestimulantes. Resistencia genética a patógenos.

Educación

  •  Biólogo, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2009
  •  Máster en Acuicultura, Universidad de Barcelona. España, 2012
  •  Doctor en Acuicultura, Universidad de Barcelona. España, 2016

Experiencia Académica

  •   Asistente de docencia Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

    Ciencias

    Valparaíso, Chile

    2007 - 2009

  •   Profesor de laboratorio Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

    Ciencias del Mar y Geografía

    Valparaíso, Chile

    2009 - 2011

  •   Profesor de curso práctico Part Time

    Universidad Autónoma de Barcelona

    Barcelona, España

    2016 - 2016

Experiencia Profesional

  •   Investigador de pregrado Full Time

    Pontificia Universidad de Valparaíso

    Valparaíso, Chile

    2008 - 2009

  •   Asistente de Investigación Full Time

    Pontificia Universidad de Valparaíso

    Valparaíso, Chile

    2009 - 2011

  •   Asistente de Investigación Other

    CYTED. Red americana de genética e inmunología para el control de patógenos en acuicultura

    Valparaíso, Chile

    2011 - 2012

  •   Investigador predoctoral Full Time

    Universidad Autónoma de Barcelona

    Barcelona, España

    2012 - 2016

  •   Investigador postdoctoral Full Time

    University of Alberta

    Edmonton, Canada

    2017 - 2019

  •   Investigador postdoctoral Full Time

    Universidad Autónoma de Barcelona

    España

    2016 - 2017

  •   Investigador postdoctoral Full Time

    Pontificia Universidad Católica de Valparaíso

    Valparaíso, Chile

    2019 - At present

Difusión y Transferencia


PARTICIPATION IN CONGRESSES

Gallardo JA, Figueroa C, Veloso P, Dixon B, Torrealba D, Afonso JM, Soto C, Conejeros P. “Familiar variation explains reduced protection of comercial vaccines against bacterial pathogens in Atlantic Salmon. International congress Aquaculture Europe 19, Berlin, Germany, October 7th to 10th 2019.

Barreda D, Wong M, Haddad F, Thomson C, Torrealba D, Heimroth R, Tierney K. “Fish thermoregulation and the promotion of cellular antimicrobial defenses” ORAL presentation at International Conference of Fish & Shellfish Immunology, Canarias, Spain, June 16th to 20th 2019.

Thwaite R, Jie J, Torrealba D, Puente-Marín S, Lucas E, Ortega-Villaizán M, Roher N. “Immunogenic protein nanopellets a new approach to combat viral diseases in farmed fish” POSTER at Sao Paulo School of Advanced Science on Vaccines. Sao Paulo State, Brazil, November 22nd to December 02nd 2018.

Torrealba D, Thomson C, Barreda D. “Dynamic housing temperature improves the immune response of goldfish to in vivo Aeromonas veronii challenge” ORAL presentation at the 14th Congress of International Society of Developmental and Comparative Immunology. Santa Fe, New Mexico, USA, 17th to 21st June 2018.

Barreda D, Wong M, Thomson C, Torrealba D, Haddad F. “Contributions of temperature to the efficiency of fish cellular immunity” ORAL presentation at the 14th Congress of International Society of Developmental and Comparative Immunology. Santa Fe, New Mexico, USA, 17th to 21st June 2018.

Torrealba D, Balasch JC, Tort L, Mackenzie S, Roher N. "The ?7 nicotinic acetylcholine receptor modulates the immune response to Poly (I:C) in trout (Oncorhynchus mykiss) macrophages". ORAL presentation at the 13th Congress of International Society of Developmental and Comparative Immunology. Murcia, Spain, 28th May to 3rd June 2015.

Torrealba D, Mackenzie S, Nerea R. "Molecular and functional characterization of nicotinic acetylcholine receptor alpha 7 in rainbow trout (Oncorhynchus mykiss)". ORAL presentation at the 11th International Congress on the Biology of Fish. Edinburgh, Scotland 3-7th Aug. 2014.

ARTICLES AND DIFFUSION

Torrealba D. “Protein Nanoparticles as candidates for Inmmunostimulants in Aquaculture”. ORAL presentation in Webinar. Advances in biotechnology, uses, applications and impacts on society. Red de Investigadores Chilenos en Canadá, REDICEC. 7th July 2017.

Torrealba D. “Molecular characterization of the inflammatory reflex and immune response modulation to fight fish infections” Article in AquacTIC, 2017.

COURSE

Teacher of Practical Course, 2016.
Institute of Biotechnology and Biomedicine, Autonomous University of Barcelona. Practice course of expression and purification of protein nanoparticles.


Premios y Distinciones

  •   Best ORAL presentation Award

    International Society of Developmental and Comparative Immunology

    España, 2015

    Torrealba D, Balach JC, Tort L, Mackenzie S, Roher N. "The alpha7 nicotinic acetylcholine receptor modulates the immune response to Poly (I:C) in trout (Oncorhynchus mykiss) macrophages". Murcia, Spain, 28th May to 3rd June 2015.

  •   Awarded a Travel Fellowship to attend the ISDCI

    International Society of Developmental and Comparative Immunology

    Chile, 2015

    13th Congress of the International Society of Developmental and Comparative Immunology.

  •   Awarded a Travel Fellowship to attend the ISDCI

    International Society of Developmental and Comparative Immunology

    Estados Unidos, 2018

    14th Congress of the International Society of Developmental and Comparative Immunology.

  •   Best Graduate, Aquaculture Master’s Program

    Universidad de Barcelona

    España, 2012

    Inter-university Master’s in Aquaculture UB-UAB-UPC. Ranked 1st in the class for the academic performance 2011-2012.

  •   Tesis doctoral con distinción Cum laude

    Universidad de Barcelona

    España, 2016

    Thesis title: "Molecular characterization of the inflammatory reflex and immune response modulation to fight fish infections". Excellent, Cum laude.


 

Article (14)

Differential Effects of Drinking Water Quality on Phagocyte Responses of Broiler Chickens Against Fungal and Bacterial Challenges
Host genetic variation explains reduced protection of commercial vaccines against Piscirickettsia salmonis in Atlantic salmon
Nanostructured recombinant protein particles raise specific antibodies against the nodavirus NNV coat protein in sole
Fish thermoregulation and the promotion of cellular antimicrobial defenses
Nanostructured TNF alpha protein targets the zebrafish (Danio rerio) immune system through mucosal surfaces and improves the survival after Mycobacterium marinum lethal infection
Functional evidence for the inflammatory reflex in teleosts: A novel alpha 7 nicotinic acetylcholine receptor modulates the macrophage response to dsRNA
Protein Nanoparticles Made of Recombinant Viral Antigens: A Promising Biomaterial for Oral Delivery of Fish Prophylactics
Coinfection takes its toll: Sea lice override the protective effects of vaccination against a bacterial pathogen in Atlantic salmon
Complex Particulate Biomaterials as Immunostimulant-Delivery Platforms
Nanostructured recombinant cytokines: A highly stable alternative to short-lived prophylactics
Nanodelivery Systems as New Tools for Immunostimulant or Vaccine Administration: Targeting the Fish Immune System
Zebrafish liver (ZFL) cells are able to mount an anti-viral response after stimulation with Poly (I:C)
Quantitative genetic basis for resistance to Caligus rogercresseyi sea lice in a breeding population of Atlantic salmon (Salmo salar)
ARTIFICIAL SETTLEMENT OF SEA LICE, CALIGUS ROGERCRESSEYI BOXSHALL & BRAVO, 2000 (COPEPODA, CALIGIDAE), ON TISSUES OF FISH USED AS SUBSTRATE

BookSection (1)

Innate Immunity Provides Biomarkers of Health for Teleosts Exposed to Nanoparticles

ConferencePoster (11)

Familiar variation explains reduced protection of commercial vaccines against bacterial pathogens in Atlantic salmon
Contributions of temperature to the efficiency of fish cellular immunity
Dynamic housing temperature improves the immune response of goldfish to in vivo Aeromonas veronii challenge
Immunogenic Protein Nanopellets: A new approach to generating immune protection in farmed fish
Zebrafish intubation as a model to study mucosal immunity: TNFα protein nanoparticles protect zebrafish against Mycobacterium marinum challenge
Protein-nanoparticles as Immunostimulant-delivery platform for fish immunization
The α7 nicotinic acetylcholine receptor modulates the immune response to Poly (I:C) in trout (Oncorhynchus mykiss) macrophages
Bacterial proteín nanoparticles for fish disease protection
Molecular and functional characterization of nicotinic acetylcholine receptor alpha 7 in rainbow trout (Oncorhynchus mykiss)
Evaluation of genetic resistance of Atlantic salmon (Salmo salar) to the Chilean sea lice Caligus rogercresseyi using classical techniques of quantitative genetics
Experimental evaluation of the settlement of Caligus rogercresseyi in tissues of a wild host (Eleginops maclovinus) and an exotic host (Oncorhynchus mykiss)

Proyecto (10)

Comparative analysis of leukocyte functional antimicrobial responses in fish
Functional Bioassay Platform for Environmental Monitoring.
Desarrollo de sistemas específicos de nanodelivery para especies de interés acuícola=> plataformas de entrega mediante nanoliposomas y nanopartículas proteicas.
Acciones de dinamización "Redes de excelencia" programa estatal de investigación científica y técnica de excelencia.
Contributions of water quality to production animal health
Grupo de excelencia en Acuicultura.
Desarrollo de nanoliposomas como vehículos de immunoestimulantes/vacunas en especies de interés para la acuicultura
Caracterización molecular del reflejo inflamatorio y modulación de la respuesta inmune frente a infecciones en peces
Ibero-american network of genetics and immunology to control pathogens in aquaculture
Desarrollo de una nueva metodología para la identificación y selección de salmónidos genéticamente resistentes al ectoparásito Caligus rogercresseyi.
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Debora Torrealba

Investigador Postdoctoral

Escuela de Ciencias del Mar

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

2
Jose Gallardo

Profesor Adjunto

Facultad de Ciencias del Mar y Geografía

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Paulina Bustos

Investigadora Postdoctoral

Facultad de Ciencias

Universidad de Valparaíso

Valparaíso, Chile

1
Pablo Conejeros

Profesor Adjunto

Universidad de Valparaiso

Valparaiso, Chile

1
Eva Vallejos

Profesor Asociado

Facultad de Medicina Veterinaria y Agronomía

Universidad de Las Américas

Santiago, Chile