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Vasko Kramer

Head of R&D

Positronmed Ltd. (Prestaciones Medicas AyC Ltda.)

Santiago, Chile

Líneas de Investigación


Investigación y desarrollo de radiofármacos para la obtención de imágenes PET y el tratamiento en oncología. Investigación traslacional de radiofármacos y coordinación de estudios clínicos en estrecha colaboración con especialidades asociadas.

Educación

  •  Química radiofarmaceutica, Johannes Gutenberg-Universidad Mainz. Alemania, 2012
  •  Quimica, Johannes Gutenberg-Universidad Mainz. Chile, 2008

Experiencia Académica

  •   Asistente cientifico Full Time

    JOHANNES GUTENBERG UNIVERSITAT MAINZ

    Quimica

    Mainz, Alemania

    2008 - 2012

Experiencia Profesional

  •   Asesor I+D Part Time

    Positronmed Ltda

    Santiago, Chile

    2013 - At present

  •   Gerente I+D Part Time

    Positronpharma SA

    Santiago, Chile

    2012 - At present

  •   Gerente General Other

    Acrux Radiopharma Consulting SpA

    Santiago, Chile

    2012 - At present

Difusión y Transferencia


Co-Organizer of the Theranostic World Congress (TWC) 2022 in Wiesbaden:
https://www.twc-2022.org/



 

Article (19)

Al[F-18]F-NOTA-Octreotide Is Comparable to [Ga-68]Ga-DOTA-TATE for PET/CT Imaging of Neuroendocrine Tumours in the Latin-American Population

Hurtado de Mendoza, Ana; Eppard, Elisabeth; Emmanuel, Noemie; Wettlin, Johanna

Article ISI
CANCERS  (2023)

Head-to-Head Intra-Individual Comparison of Biodistribution and Tumor Uptake of [18F]FAPI-74 with [18F]FDG in Patients with PDAC: A Prospective Exploratory Study

Novruzov, Emil; Giesel, Frederik; Mori, Yuriko et al.

Article
CANCERS  (2023)

Synthesis and in vivo evaluation of [C-11]tucatinib for HER2-targeted PET imaging

Mueller, Marius; Hvass, Lars; Jorgensen, Jesper T.; Staudt, Markus; Battisti, Umberto Maria; Kjaer, Andreas

Article ISI
BIOORGANIC MEDICINAL CHEMISTRY LETTERS  (2023)

Development and evaluation of an 18F-labeled nanobody to target SARS-CoV-2's spike protein

Lopes van den Broek, Sara, García-Vázquez, Rocío, Andersen, Ida Vang, Valenzuela-Nieto, Guillermo, Shalgunov, Vladimir, Battisti, Umberto M. et al.

Article
Frontiers in Nuclear Medicine  (2022)

Whole-body biodistribution and radiation dosimetry of [F-18]PR04.MZ: a new PET radiotracer for clinical management of patients with movement disorders

Lehnert, Wencke; de Mendoza, Ana Hurtado; Ilheu, Marcelo

Article ISI
EJNMMI RESEARCH  (2022)

A theranostic approach of [68Ga] Ga-DOTA. SA. FAPi PET/CT-guided [177Lu] Lu-DOTA. SA. FAPi radionuclide therapy in an end-stage breast cancer patient: new frontier in targeted …

ArunRaj, ST

Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2021)

Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu] Lu-PSMA-ALB-56 in patients with mCRPC

Jimenez-Franco, DL

Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2021)

Biodistribution, pharmacokinetics, dosimetry of [68Ga] Ga-DOTA. SA. FAPi, and the head-to-head comparison with [18F] F-FDG PET/CT in patients with various cancers

ArunRaj, T; Sarswat, S

Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2021)

Evaluation of Safety and Dosimetry of 177Lu-DOTA-ZOL for Therapy of Bone Metastases

Wencke, L; Jimenez-Franco, LD; Zhernosekov, K

Article
JOURNAL OF NUCLEAR MEDICINE  (2021)

FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?

Dendl, K; Koerber, S; Cardinale, J; Dabir, M; Novruzov, E; Watabe, T

Article
Pharmaceuticals  (2021)

First-In-Human Results on the Biodistribution, Pharmacokinetics, and Dosimetry of [177Lu]Lu-DOTA.SA.FAPi and [177Lu]Lu-DOTAGA.(SA.FAPi)2

Ballal, S; Yadav, MP; Kumari, S; Bal, CS

Article
Pharmaceuticals  (2021)

Characterization of the serotonin 2A receptor selective PET tracer (R)-[F-18]MH.MZ in the human brain

Dyssegaard A.; Knudsen G.M.; Herth M.M.

Article ISI SCOPUS
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2020)

Evaluation of [F-18]-N-Methyl lansoprazole as a Tau PET Imaging Agent in First-in-Human Studies

Koeppe R.A.; Raffel D.M.; Frey K.A.; Scott P.J.H.

Article ISI SCOPUS
ACS Chemical Neuroscience  (2020)

Detection Efficacy of F-18-PSMA-1007 PET/CT in 251 Patients with Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy

Giesel, FL; Knorr, K; Spohn, F; Will, L; Maurer, T; Flechsig, P; Neels, O; Schiller, K; Weber, WA; Haberkorn, U; et al.

Article ISI SCOPUS
JOURNAL OF NUCLEAR MEDICINE  (2019)

Pharmacokinetic evaluation of [F-18]PR04.MZ for PET/CT imaging and quantification of dopamine transporters in the human brain

Pruzzo R.; Rösch F.

Article ISI SCOPUS
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2019)

Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands

Rafique, W; Pardo, T; Smits, R; Spilhaug, MM; Hoepping, A; Savio, E; Engler, H; Kuljs, R; Riss, PJ

Article ISI SCOPUS
ACS OMEGA  (2018)

F-18-Labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging

Debus, Fabian; Buchholz, Hans-Georg; Bausbacher, Nicole; Lueddens, Hartmut

Article ISI
NUCLEAR MEDICINE AND BIOLOGY  (2010)

Structural Combination of Established 5-HT2A Receptor Ligands: New Aspects of the Binding Mode

Santini, Martin A.

Article ISI
CHEMICAL BIOLOGY & DRUG DESIGN  (2010)

Synthesis and in vitro affinities of various MDL 100907 derivatives as potential F-18-radioligands for 5-HT2A receptor imaging with PET

Herth, Matthias M.; Kramer, Vasko; Piel, Markus; Palner, Mikael; Riss, Patrick J.; Knudsen, Gitte M.; Roesch, Frank

Article ISI
BIOORGANIC & MEDICINAL CHEMISTRY  (2009)

Abstract (3)

[18F] PR04.MZ for Dopamine Transporter Quantification in Low Density Regions - Complete Evaluation and Dosimetry in Healthy Volunteers

Kramer V.; Pruzzo R.; Hernandez, E.; Chana, P; Juri C.; Riss, P; Rosch, F; Amaral H.

Abstract ISI
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2015)

Quantification of 5HT2A-Receptors in the Human Brain with [18F]MHMZ

Kramer V.; Herth, M; Hernandez, E.; Juri C.; Pruzzo R.; Rosch, F; Amaral H.

Abstract ISI
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2015)

[18F]PR04. MZ for Quantification of Striatal and Extrastriatal Dopamine Transporters in Patients with Idiopathic Parkinson's Disease

Amaral H.; Kramer V.; Pruzzo R.; Chana, P; Juri C.; Piel M.; Galaz, R; Coudeu, I; Rosch, F

Abstract ISI
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING  (2013)

EditorialMaterial (1)

Imaging Nigrostriatal Dopaminergic Deficit in Holmes Tremor with F-18-PR04.MZ-PET/CT

Juri C.; Chana, P; Kramer V.; Pruzzo R.; Amaral H.; Riss, PJ; Rosch, F

EditorialMaterial ISI
CLINICAL NUCLEAR MEDICINE  (2015)

Proyecto (5)

A new production method for a radioisotope used for non-invasive diagnose and monitoring of prostate cancer

CORFO (16ITE2-67729)

Proyecto
2017-2019
Coinvestigador(a)

Manifestaciones prodrómicas de la Enfermedad de Parkinson en un grupo de alto riesgo=> personas con síndrome de microdeleción 22q11.2

FONDECYT (FONDECYT 1)

Proyecto
2017-2020
Coinvestigador(a)

Radiopharmaceuticals to visualize neurofibrillary tangles in vivo

CORFO (14IEAT-28666)

Proyecto
2014-2018
Investigador(a)

Desarrollo, Implementación y Validación Clínica de Radiofármacos para la Detección Temprana y Diferencial de la Enfermedad de Parkinson mediante Neuroimágenes PET/CT para el Mercado Nacional e Internacional

CORFO (13PEI21682)

Proyecto
2013-2017
Investigador(a)

Extrastriatal Dopaminergic Function in REM Sleep Behavioral Disorder

FONDECYT (11130534)

Proyecto
2013-2016
Personal técnico y/o de apoyo

5
CARLOS JURI

ASSISTANT PROFESSOR

NEUROLOGY

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

4
Pedro Chana Cuevas

Profesor Titular

Facultad de Ciencias Medicas

Universidad de Santiago

Santiago, Chile

23
Vasko Kramer

Head of R&D

Investigación y Desarrollo

Positronmed Ltd. (Prestaciones Medicas AyC Ltda.)

Santiago, Chile