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Luis Alberto Cordova Jara

Academico

Universidad de Chile

Santiago , Chile

Micro-ambiente óseo y osteolísis: aplicación al aflojamiento aséptico peri-protésico de implantes articulares totales 2010-2014 Immunomodulation of osteogenesis 2014-2016 Wnt signaling pathway in bone grafting 2016-2017

Cirujano Dentista , UNIVERSIDAD DE CHILE. Chile, 1996
Especialista Cirugia y Traumatologia Maxilofacial , UNIVERSIDAD DE CHILE. Chile, 2002
Biomedicina , UNIVERSIDAD DE CHILE. Chile, 2010
Biomedicina Biología ósea , UNIVERSITE DE NANTES. Francia, 2014
Postdoctoral Fellow, STANFORD UNIVERSITY. Estados Unidos, 2017

Profesor Full Time

UNIVERSIDAD DE CHILE

Odontologia

Santiago, Chile

2001 - At present

Especialista Cirugia Maxilofacial Part Time

Hospital San Jose

Chile

2004 - At present


Dysregulated healing response participates in the pathophysiology of temporomandibular joint ankylosis Córdova L.A. Article J Craniomaxillofac Surg . (2021)
Osteoimmunology drives dental implant osseointegration: A new paradigm for implant dentistry Cordova, LA Article Jpn Dent Sci Rev. (2021)
Histatin-1 counteracts the cytotoxic and antimigratory effects of zoledronic acid in endothelial and osteoblast-like cells Castro, Martín; Torres, Pedro; Solano, Luis; Córdova, Luis A.; Torres, Vicente A. Article ISI SCOPUS JOURNAL OF PERIODONTOLOGY (2019)
Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery Arruda, DC; Gonzalez, IJ; Finet, S; Cordova, L.; Trichet, V; Andrade, GF; Hoffmann, C; Bigey, P; Macedo, WAD; Cunha, AD; de Souza, AM; Escriou, V Article ISI SCOPUS JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)
A WNT protein therapeutic improves the bone-forming capacity of autografts from aged animals Chen, T; Li, JT; Cordova, LA; Liu, B; Mouraret, S; Sun, Q; Salmon, B; Helms, J Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
CCL2, CCL5, and IGF-1 participate in the immunomodulation of osteogenesis during M1/M2 transition in vitro Córdova L.A.; Loi F.; Lin T.-H.; Gibon E.; Pajarinen J.; Nabeshima A.; Lu L.; Yao Z.; Goodman S.B. Article ISI SCOPUS JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)
Mutant CCL2 protein coating mitigates wear particle-induced bone loss in a murine continuous polyethylene infusion model Nabeshima A.; Pajarinen J.; Lin T.-H.; Jiang X.; Gibon E.; Córdova L.A.; Loi F.; Lu L.; Jämsen E.; Egashira K.; Yang F.; Yao Z.; Goodman S.B. Article ISI SCOPUS BIOMATERIALS (2017)
Orthopaedic wear particle-induced bone loss and exogenous macrophage infiltration is mitigated by local infusion of NF-kappa B decoy oligodeoxynucleotide Lin T.; Pajarinen J.; Nabeshima A.; Córdova L.A.; Loi F.; Gibon E.; Lu L.; Nathan K.; Jämsen E.; Yao Z.; Goodman S.B. Article ISI SCOPUS JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)
Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway Lu, LY; Loi, F; Nathan, K; Lin, TH; Pajarinen, J; Gibon, E; Nabeshima, A; Cordova, L; Jamsen, E; Yao, ZY; Goodman, SB Article ISI SCOPUS Journal of Orthopaedic Research (2017)
Relationships among Bone Quality, Implant Osseointegration, and Wnt Signaling Li J.; Yin X.; Huang L.; Mouraret S.; Brunski J.B.; Cordova L.; Salmon B.; Helms J.A. Article ISI SCOPUS JOURNAL OF DENTAL RESEARCH (2017)
Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing Gibon, E.; Loi, F.; Cordova, Luis A.; Pajarinen, J.; Lin, T.; Lu, L.; Nabeshima, A.; Yao, Z.; Goodman, Stuart B. Article WOS-ESCI REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE (2016)
Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-B activity Lin T.-H.; Gibon E.; Loi F.; Pajarinen J.; Córdova L.A.; Nabeshima A.; Lu L.; Yao Z.; Goodman S.B. Article ISI SCOPUS JOURNAL OF ORTHOPAEDIC RESEARCH (2016)
NF-kappa B decoy oligodeoxynucleotide mitigates wear particle-associated bone loss in the murine continuous infusion model Lin, TH; Pajarinen, J; Sato, T; Loi, F; Fan, CC; Cordova, LA; Nabeshima, A; Gibon, E; Zhang, R; Yao, ZY; Goodman, SB Article ISI SCOPUS Acta Biomaterialia (2016)
Pro-osteoclastic in vitro effect of Polyethylene-like nanoparticles: Involvement in the pathogenesis of implant aseptic loosening Brulefert, K; Cordova, LA; Brulin, B; Faucon, A; Hulin, P; Nedellec, S; Gouin, F; Passuti, N; Ishow, E; Heymann, D Article ISI SCOPUS JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2016)
Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw Cordova, LA; Guilbaud, F; Amiaud, J; Battaglia, S; Charrier, C; Lezot, F; Piot, B; Redini, F; Heymann, D Article ISI SCOPUS JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY (2016)
The effects of immunomodulation by macrophage subsets on osteogenesis in vitro Loi, F.; Cordova, LA; Zhang, R; Pajarinen, J.; Lin, TH; Goodman, SB; Yao, ZY Article ISI SCOPUS STEM CELL RESEARCH & THERAPY (2016)
Are Fluorescent Organic Nanoparticles Relevant Tools for Tracking Cancer Cells or Macrophages? Faucon, A; Benhelli-Mokrani, H; Cordova, LA; Brulin, B; Heymann D.; Hulin, P; Nedellec, S; Ishow, E Article ISI SCOPUS Advanced Healthcare Materials (2015)
Inhibition of osteolysis and increase of bone formation after local administration of siRNA-targeting RANK in a polyethylene particle-induced osteolysis model Córdova L.A.; Trichet, V; Escriou, V; Rosset P.; Amiaud J.; Battaglia S.; Charrier C.; Berreur M.; Brion R.; Gouin F.; Layrolle P.; Passuti N.; Heymann D. Article ISI SCOPUS Acta Biomaterialia (2015)
Giant canine with dentine anomalies in oculo-facio-cardio-dental syndrome Larhant, Matthieu; Sourice, Sophie; Grimaud, Fanny; Cordoba, Luis; Leveau, Sophie; Huet, Pascal; Corre, Pierre; Khonsari, Roman Hossein Article ISI JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY (2014)
Medial proximal tibia donor site: Contribution to alveolar cleft repair in children Corre P.; Khonsari, RH; Laure B.; Jara, LC; Bonnet R.; Mercier, JM Article ISI SCOPUS Revue de Stomatologie et de Chirurgie Maxillo-Faciale (2011)


NF-kappa B as a Therapeutic Target in Inflammatory-Associated Bone Diseases Lin T.-H.; Pajarinen J.; Lu L.; Nabeshima A.; Cordova L.A.; Yao Z.; Goodman S.B. BookWhole ISI SCOPUS CHROMATIN PROTEINS AND TRANSCRIPTION FACTORS AS THERAPEUTIC TARGETS (2017)


Antiangiogenic Effect of Triamcinolone Associated with Lidocaine with Epinephrine for Dental use in Chicken Chorioallantoic Membrane Mardones M,; Bravo, R; Cordova, LA; Santana J.; Zamorano, C; Lemus D JournalWhole Mardones M, Bravo R, Cordova LA, Santana J, Zamorano C, Lemus D. Antiangiogenic Effect of Triamcinolone Associated with Lidocaine with Epinephrine for Dental use in Chicken Chorioallantoic Membrane. International journal of morphology = Revista internacional de morfología. 2019; 37(1):344-348. (2019)


Habilitación de una Unidad de Microcirugía Experimental en el Bioterio de Facultad de Odontología de la Universidad de Chile. Cordova, LA; Cavalla, Franco; Dutzan, Nicolas Proyecto (2019)
Immunomodulating bone healing for the aging via macrophages - osteoprogenitor cells interaction Córdova LA Proyecto (2019)
Wnt signaling pathway in bone grafting PFCHA (CONICYT PA) Proyecto 2016-2017 Postdoctorado
Wnt signaling pathway in bone grafting NIH (R01-DE 024000-12) Proyecto 2016-2017 Postdoctorado
Immunomodulation of osteogenesis PFCHA (CONICYT PA) Proyecto 2014-2016 Postdoctorado
Immunomodulation of osteogenesis NIH (R01-DE 024000-00) Proyecto 2014-2016 Postdoctorado
Caracterización histológica e inmuhistoquímica de muestras humanas de anquilosis temporomandibular Fondos de Investigación Odontología Universidad de Chile (FIOUCH) (FIOUCh 13-004) Proyecto 2013-2015 Coinvestigador(a)
Développement d'un modèle animal murin pour l'étude de la phsyiopathologie de l'ostéonécrose des maxillaires => applications aux bisphosphonates et aux inhibiteurs e RANKL (ONMLBP) Fondation des “Gueules Cassées” (14-2012) Proyecto 2011-2012 Inv. Responsable
Micro-ambiente óseo y osteolísis=> aplicación al aflojamiento aséptico peri-protésico de implantes articulares totales PFCHA (CONICYT PA) Proyecto 2010-2014 Tesista
Micro-ambiente óseo y osteolísis=> aplicación al aflojamiento aséptico peri-protésico de implantes articulares totales Agence Nationale de la Recherche (ANR)- Francia (Project N°RO 7196N) Proyecto 2010-2014 Tesista


Osteoimmunology of Oral and Maxillofacial Diseases: Translational Applications Based on Biological Mechanisms Alvarez C.; Monasterio G.; Cavalla F.; CÃ³rdova L.A.; HernÃ¡ndez M.; Heymann D.; Garlet G.P.; Sorsa T.; PÃ¤rnÃ¤nen P.; Lee H.-M.; Golub L.M.; Vernal R.; Kantarci A. Review ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction Gibon E.; Córdova L.A.; Lu, L; Lin T.-H.; Yao, Z; Hamadouche M.; Goodman S.B. Review ISI SCOPUS JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2017)
Inflammation, fracture and bone repair Loi, F.; Córdova L.A.; Pajarinen, J.; Lin T.-H.; Yao, Z; Goodman S.B. Review SCOPUS Bone (2016)
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery Brignardello Petersen, R; Carrasco Labra, A; Araya, I.; Yanine N.; Jara, LC; Villanueva J. Review ISI COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2015)
Orthopaedic implant failure: aseptic implant loosening - the contribution and future challenges of mouse models in translational research Cordova, LA; Stresing, V; Gobin, B; Rosset P.; Passuti N.; Gouin F.; Trichept, V; Layrollet, P; Feymann, D Review ISI SCOPUS CLINICAL SCIENCE (2014)