2020-05-26-185927.jpg_thumb90

David Adrián Sáez San Martín

Investigador Postdoctoral

Universidad de Concepción

Concepción, Chile

Líneas de Investigación


Molecular Dynamics, Enzymatic Catalysis, Enzymatic Design

Educación

  •  Química, UNIVERSIDAD DE CONCEPCION. Chile, 2017
  •  Química y Farmacia, UNIVERSIDAD DE CONCEPCION. Chile, 2012

Experiencia Académica

  •   Colaborador Docente Part Time

    UNIVERSIDAD DE CONCEPCION

    Farmacia

    Concepcion, Chile

    2018 - At present


 

Article (8)

Covalent Adduct Formation as a Strategy for Efficient CO2 Fixation in Crotonyl-CoA Carboxylases/Reductases
Atom-Condensed Fukui Function in Condensed Phases and Biological Systems and Its Application to Enzymatic Fixation of Carbon Dioxide
Awakening the Sleeping Carboxylase Function of Enzymes: Engineering the Natural CO2-Binding Potential of Reductases
Electronic structure benchmark calculations of inorganic and biochemical carboxylation reactions
Four amino acids define the CO2 binding pocket of enoyl-CoA carboxylases/reductases
Catalytic Reaction Mechanism in Native and Mutant Catechol-O-methyltransferase from the Adaptive String Method and Mean Reaction Force Analysis
The effect of the environment on the methyl transfer reaction mechanism between trimethylsulfonium and phenolate
A consistent S-Adenosylmethionine force field improved by dynamic Hirshfeld-I atomic charges for biomolecular simulation

Proyecto (7)

Mechanisms Governing CO2/ O2 Specificity in RuBisCO from Multiscale Computer Simulations
NADPH, 1,4-Dihydropyridines and Unsaturated Compounds: Exploring the Main Reducing Strategy of Nature.
REDCO2:Rational Enzyme Design for CO2 fixation
Max Planck Partner Group=> A mechanistic model for CO2 fixation of Ccr enzymes from QM/MM simulations and mutational studies.
Núcleo Milenio Procesos Químicos y Catálisis
ON THE TRACK OF ENZYMES' FUNCTION=> NEW INSIGHTS FROM THE MEAN REACTION FORCE
ON THE TRACK OF ENZYMES' FUNCTION=> NEW INSIGHTS FROM THE MEAN REACTION FORCE
11
David Sáez

Investigador Postdoctoral

Universidad de Concepción

Concepción, Chile

7
Esteban Vohringer-Martinez

Profesor Asociado

Físico-Química

FACULTAD DE CIENCIAS QUÍMICAS

Concepción, Chile

1
Javier Oller

Investigador Postdoctoral

Universidad de Chile

Santiago de Chile, Chile

1
Aharon Gomez

Docente

Departamento de Ciencias Biológicas y Químicas

Universidad San Sebastián

Concepción, Chile

1
Alejandro Toro

PROFESOR TITULAR

Química Física

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile