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Carlos Alberto Rozas Salas

Profesor asistente

Universidad de Santiago de Chile

Santiago, Chile

Enfermedades neurodegenerativas, Plasticidad sináptica, Síndrome de déficit atencional y Neurociencia y educación.

Neurociencia, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2011

Profesor Asistente Full Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Facultad de Quimica y Biología

Santiago, Chile

2014 - At present

2018. Tesis de Doctorado. Darwin Contreras Pacheco, Doctorado en Neurociencia, Universidad de Santiago de Chile, Tesis: Efecto de Metilfenidato en la transmisión sináptica glutamatergica hipocampal en un modelo nicotínico de trastorno de déficit atencional e hiperactividad.

Programa1000 Científicos 1000 Aulas, Explora-Conicyt. charla "Neurociencia y educación" en el colegio St Elena Carmelitas Mision Teresiana, Santiago. Octubre 2014
Programa1000 Científicos 1000 Aulas, Explora-Conicyt. charla "Neurociencia y educación" en el colegio INSTITUTO SANTA TERESA DE LOS ANDES, Graneros VI REGION Octubre 2014
Programa1000 Científicos 1000 Aulas, Explora-Conicyt ,Charla de difusión científica "Neurociencia y Educación", Complejo Educacional Chimbarongo, Chimbarongo, Region de OHiggings mayo 2011
Programa1000 Científicos 1000 Aulas, Explora-Conicyt,Charla de difusión científica "Neurociencia y Educación", Colegio José Abelardo Nuñez, Puente Alto, Region Metropolitana mayo 2011
Programa1000 Científicos 1000 Aulas, Explora-Conicyt ,Charla de difusión científica "Neurociencia y Educación", Colegio Alberto Hurtado, Pudahuel, Region Metropolitana mayo 2009

Premio a la Bidireccionalidad 2017 VIME-USACH

UNIVERSIDAD DE SANTIAGO DE CHILE

Chile, 2017

Premio a la Bidireccionalidad 2017 VIME-USACH por el proyecto de vinculación con el medio: “Taller Latinoamericano sobre acreditación de laboratorios clínicos bajo la norma ISO 15189”, proyecto patrocinado por el Physikalisch-Technische Bundesanstalt, PTB de Alemania.


Methylphenidate Restores Behavioral and Neuroplasticity Impairments in the Prenatal Nicotine Exposure Mouse Model of ADHD: Evidence for Involvement of AMPA Receptor Subunit Composition and Synaptic Spine Morphology in the Hippocampus Contreras, Darwin; Pina, Ricardo; Carvallo, Claudia; Godoy, Felipe; Ugarte, Gonzalo; Zeise, Marc; Rozas, Carlos; Morales, Bernardo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis Medinas, Danilo Bilches; Malik, Sajid; Yildiz-Bolukbasi, Esra; Borgonovo, Janina; Saaranen, Mirva J.; Urra, Hery; Pulgar, Eduardo; Afzal, Muhammad; Contreras, Darwin; Wright, Madison T.; Bodaleo, Felipe; Quiroz, Gabriel; Rozas, Pablo; Mumtaz, Sara; Diaz, Rodrigo; Rozas, Carlos; Cabral-Miranda, Felipe; Pina, Ricardo; Valenzuela, Vicente; Uyan, Ozgun; Reardon, Christopher; Woehlbier, Ute; Brown, Robert H.; Sena-Esteves, Miguel; Gonzalez-Billault, Christian; Morales, Bernardo; Plate, Lars; Ruddock, Lloyd W.; Concha, Miguel L.; Hetz, Claudio; Tolun, Aslihan Article ISI EMBO JOURNAL (2022)
Atomoxetine Reestablishes Long Term Potentiation in a Mouse Model of Attention Deficit/Hyperactivity Disorder PiÃ±a R.; Rozas C.; Contreras D.; Hardy P.; Ugarte G.; Zeise M.L.; Rojas P.; Morales B. Article ISI SCOPUS Neuroscience (2019)
Single and Repeated Administration of Methylphenidate Modulates Synaptic Plasticity in Opposite Directions via Insertion of AMPA Receptors in Rat Hippocampal Neurons. Carvallo, Claudia; Contreras, Darwin; Ugarte, Gonzalo; Delgado, Ricardo; Pancetti, Floria; Rozas, Carlos; Piña, Ricardo; Constandil, Luis; Zeise, Marc L; Morales, Bernardo Article Frontiers in pharmacology (2018)
Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous Î²-Amyloid Levels. García-Rojo, Gonzalo; Gámiz, Fernando; Ampuero, Estíbaliz; Rojas-Espina, Daniel; Sandoval, Rodrigo; Rozas, Carlos; Morales, Bernardo; Wyneken, Ursula; Pancetti, Floria Article Frontiers in pharmacology (2017)
Methylphenidate amplifies long-term potentiation in rat hippocampus CA1 area involving the insertion of AMPA receptors by activation of Î²-adrenergic and D1/D5 receptors. Rozas, C; Carvallo, C; Contreras, D; Carreño, M; Ugarte, G; Delgado, R; Zeise, M L; Morales, B Article Neuropharmacology (2015)
Rescue of homeostatic regulation of striatal excitability and locomotor activity in a mouse model of Huntington's disease. Cao, Yumei; Bartolomé-Martín, David; Rotem, Naama; Rozas, Carlos; Dellal, Shlomo S; Chacon, Marcelo A; Kadriu, Bashkim; Gulinello, Maria; Khodakhah, Kamran; Faber, Donald S Article Proceedings of the National Academy of Sciences of the United States of America (2015)
Associative Hebbian Synaptic Plasticity in Primate Visual Cortex Shiyong Huang, Carlos Rozas, Mario Treviño, Jessica Contreras, Sunggu Yang, Lihua Song, Takashi Yoshioka, Hey-Kyoung Lee and Alfredo Kirkwood Article The Journal of Neuroscience (2014)
MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression. Benoist, Marion; Palenzuela, Rocío; Rozas, Carlos; Rojas, Patricio; Tortosa, Elena; Morales, Bernardo; González-Billault, Christian; Ávila, Jesús; Esteban, José A Article The EMBO journal (2013)
Acutely applied MDMA enhances long-term potentiation in rat hippocampus involving D1/D5 and 5-HT2 receptors through a polysynaptic mechanism. Rozas, C; Loyola, S; Ugarte, G; Zeise, M L; Reyes-Parada, M; Pancetti, F; Rojas, P; Morales, B Article European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology (2012)
Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region Carlos Rozas, Ramón A. Lorca, Sebastian Loyola, Sandra Moreira-Ramos, Marc L. Zeise, Alfredo Kirkwood, J. Pablo Huidobro-Toro and Bernardo Morales Article The European journal of neuroscience (2011)
MDMA ("ecstasy") impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats. Arias-Cavieres, Alejandra; Rozas, Carlos; Reyes-Parada, Miguel; Barrera, Nelson; Pancetti, Floria; Loyola, Sebastian; Lorca, Ramón A; Zeise, Marc L; Morales, Bernardo Article Neuroscience letters (2010)
Oxidative damage in lymphocytes of copper smelter workers correlated to higher levels of excreted arsenic. Escobar, Jorge; Varela-Nallar, Lorena; Coddou, Claudio; Nelson, Pablo; Maisey, Kevin; Valdés, Daniel; Aspee, Alexis; Espinosa, Victoria; Rozas, Carlos; Montoya, Margarita; Mandiola, Cristian; Rodríguez, Felipe E; Acuña-Castillo, Claudio; Escobar, Alejandro; Fernández, Ricardo; Diaz, Hernán; Sandoval, Mario; Imarai, Mónica; Rios, Miguel Article Mediators of inflammation (2010)
Effect of short-term exposure to dichlorvos on synaptic plasticity of rat hippocampal slices: involvement of acylpeptide hydrolase and alpha(7) nicotinic receptors. Olmos, Cristina; Sandoval, Rodrigo; Rozas, Carlos; Navarro, Sebastián; Wyneken, Ursula; Zeise, Marc; Morales, Bernardo; Pancetti, Floria Article Toxicology and applied pharmacology (2009)
Noncholinesterase effects induced by organophosphate pesticides and their relationship to cognitive processes: implication for the action of acylpeptide hydrolase. Pancetti, Floria; Olmos, Cristina; Dagnino-Subiabre, Alexies; Rozas, Carlos; Morales, Bernardo Article Journal of toxicology and environmental health. Part B, Critical reviews (2007)
Developmental inhibitory gate controls the relay of activity to the superficial layers of the visual cortex. Rozas, C; Frank, H; Heynen, A J; Morales, B; Bear, M F; Kirkwood, A Article The Journal of neuroscience : the official journal of the Society for Neuroscience (2001)
Spatiotemporal profile of synaptic activation produced by the electrical and visual stimulation of retinal inputs to the optic tectum: a current source density analysis in the pigeon (Columba livia). Letelier, J C; Mpodozis, J; Marin, G; Morales, D; Rozas, C; Madrid, C; Velasco, M Article The European journal of neuroscience (2000)
Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine. Kirkwood, A; Rozas, C; Kirkwood, J; Perez, F; Bear, M F Article The Journal of neuroscience : the official journal of the Society for Neuroscience (1999)
[Critical period of cortical plasticity]. Morales, B; Rozas, C; Pancetti, F; Kirkwood, A Article Revista de neurologia (0)


EFFECT OF METHYLPHENIDATE ON BEHAVIOR AND SYNAPTIC PLASTICITY IN A MURINE MODEL OF ATTENTION DEFICIT-HYPERACTIVITY DISORDER FONDECYT (1161524) Proyecto 2016-2020 Coinvestigador(a)
OPTOGENETIC STUDY OF SEROTONERGIC MODULATION OF STRIATAL EXCITABILITY IN HUNTINGTON'S DISEASE FONDECYT (11140430) Proyecto 2014-2017 Inv. Responsable
Activity-dependent modulation of intrinsic membrane properties of striatal neurons in normal and Huntington's disease mice CHDI Foundation (A-5376) Proyecto 2012-2015 Postdoctorado
Study of Glutamate release from Raphe proyections on to VTA and SN neurons using optogenetics National Institute of Health, NIH (PA-10-069) Proyecto 2010-2012 Postdoctorado
Bases celulares y moleculares del efecto de MDMA (Extasis) sobre la plasticidad sinaptica en corteza visual e hipocampo FONDECYT (1080652) Proyecto 2008-2010 Personal técnico y/o de apoyo
Regulación del período crítico de la plasticidad sináptica por inhibición GABAérgica en la corteza visual FONDECYT (1030220) Proyecto 2003-2005 Personal técnico y/o de apoyo
Monitoreo y ecología de tres especies de pingüinos en las islas Shetland del Sur Instituto Nacional Antartico (040) Proyecto 2001-2002 Investigador(a)
Regulation of synaptic plastiticy in visual cortex National Institute of Health, NIH (1R01EY012124-01) Proyecto 1997-1999 Personal técnico y/o de apoyo
Análisis espacio-temporal de la modulación sacádica de la actividad neuronal unitaria en el tectum de la paloma despierta FONDECYT (1950687) Proyecto 1995-1998 Personal técnico y/o de apoyo