Man

Carolina Patricia Ochoa Rosales

Investigador

Universidad de Concepción

Rotterdam, Chile

Líneas de Investigación


Estudio de determinantes epigenéticos, genéticos y metabólicos como factores de riesgo de enfermedades asociadas a la edad, como el deterioro cognitivo, diabetes tipo 2, enfermedad cardiovascular; con énfasis en la metilación del ADN como biomarcador

Educación

  •  Administración en Salud, UNIVERSIDAD DEL DESARROLLO. Chile, 2016
  •  Genetic Epidemiology, ERASMUS UNIVERSITY ROTTERDAM. Holanda, 2018
  •  Epidemiology, ERASMUS UNIVERSITY ROTTERDAM. Chile, 2020
  •  Bioquímica, UNIVERSIDAD DE CONCEPCION. Chile, 2012

Experiencia Académica

  •   Postdoctoral researcher Full Time

    ERASMUS UNIVERSITY ROTTERDAM

    Medical Center

    Rotterdam, Holanda

    2020 - At present

  •   Teacher assistant in Biostatistics Other

    ERASMUS UNIVERSITY ROTTERDAM

    Rotterdam, Chile

    2018 - 2018

  •   Teacher assistant in Biostatistics Other

    ERASMUS UNIVERSITY ROTTERDAM

    Netherlands Institute for Health Sciences

    Rotterdam, Holanda

    2020 - 2020

  •   Investigadora senior, co-supervisora de tesis y profesora acreditada en posgrado Full Time

    UNIVERSIDAD DE CONCEPCION

    Centro de Vida Saludable

    Concepción, Chile

    2021 - At present

  •   Docente Investigador Full Time

    UNIVERSIDAD ADOLFO IBANEZ

    Escuela de Psicología

    Chile

    2022 - At present

Experiencia Profesional

  •   Asistente de Investigación y Encargada de Calidad Full Time

    Universidad de Concepción

    Concepción, Chile

    2013 - 2016

  •   Profesor de Cátedra Other

    Universidad de las Américas

    Concepción, Chile

    2013 - 2013

  •   Visiting researcher Full Time

    University of Glasgow

    Glasgow, Reino Unido

    2019 - 2020

  •   colaborador académico Part Time

    Universidad de Concepción

    Concepción, Chile

    2012 - 2013

  •   PhD student Full Time

    Erasmus University Medical Center

    Rotterdam, Holanda

    2016 - 2020

  •   Postdoctoral researcher Part Time

    Erasmus University Medical Center

    Rotterdam, Holanda

    2020 - At present

  •   investigador Full Time

    Universidad de Concepción

    Concepción, Chile

    2021 - 2022

Formación de Capital Humano


I am currently co-supervising two master of science thesis at Erasmus University Medical Center
1. Dietary quality, blood metabolome and cardiovascular disease risk. Erasmus Medical Center, 2020 (ongoing)- student: Rianne Smit
2. Air pollution and risk of cardiovascular disease and mortality. Erasmus Medical Center, 2020 (ongoing). - student: Amber Meulenbeld

Additionally, I have been reviewer of international peer-reviewed journals: Clinical Nutrition, Revista Española de Nutrición Humana y Dietética, PLOS ONE


Difusión y Transferencia


I participated in the Explora Conicyt Día de la Ciencia en my Colegio program 2010, aimed to communicate science at schools. I went to a primary school in Ñiquén, a town in the Biobio Region. Later, when I was working at CSV in the project UCO1201 Diseño e Implementación de un Modelo Territorial Integrado para promoción de estilos de vida saludable y prevención de la obesidad, part of the time involved “field work” at the school in Hualpén city. I was part of the Healthy Living staff and used to give educative sessions to children and parents at meetings, regarding healthy lifestyles, physical activity, self-care, eating habits at home and snacks at school. In order to proceed with the technological transfer of the complete model to other schools, the protocols were registered under intellectual property, as described above. Further, I was part of the CSV team of scientific advisors that worked in the proposal “Esto es Vida” to apply for Explora CONICTY grant for science dissemination 2014, in collaboration with the Centro Interactivo de Ciencias Artes y Tecnologías CICAT. It was about stands or modules where children attending CICAT facilities could learn from science and lifestyles by performing practical activities. However, we did not obtain the funding.

Conferences
- Invited speaker in the scientific meeting “Estilos de Vida y Salud, presente y perspectivas futuras” (lifestyles and health, present and future perspectives) 2019, U. de Concepción, Chile (Annex 33).
- Invited speaker Congreso Chileno de Química Clínica. Simposio “Envejecimiento y Salud: Biomarcadores y Estilos De Vida Para Envejecimiento Saludable” (aging and health: biomarkers and lifestyles for healthy aging), 2019 (Annex 34). It had to be postponed due to the social revolution in Chile last year.
- EuroPrevent, European Society of Cardiology (ESC). Oral presentation. Winner of the Young Investigator Award, Portugal, 2019 (Annex 28)
- EPI Lifestyle Scientific Sessions, American Heart Association. Oral presentation. USA, 2019 (Annex 35)
- Annual Dutch Diabetes Research Meeting (NVDO). Oral presentation. The Netherlands, 2018 (Annex 39)
- American Diabetes Association 78th Scientific Sessions (ADA). Poster. USA, 2018.
- CHARGE Consortium conference, Hilton Hotel, Rotterdam, the Netherlands, 2018.
- Epigenetic of common diseases. Poster. England, 2017 (Annex 36)
- EASD 56th annual meeting, European Association for the study of Diabetes
- ESC Congress 2020 – The Digital Experience, European Society of Cardiology


Premios y Distinciones

  •   Best master thesis 2017-2018 developed under NIHES supervision

    ERASMUS UNIVERSITY ROTTERDAM

    Holanda, 2018

    Master thesis chosen as the bes among master of science and doctor of science thesis developed under the Netherlands Institute for Health Sciences, in the yerars 2017-2018. This master was completed in parallel to the PhD program. Certifica of the award is provided in the annexes of the application.

  •   Young Investigator Award

    European Associaiotn of Cardiology

    Portugal, 2019

    Award to yhr Young researcher for the work entitled Epigenetic marker partially mediates the association between statin therapy and type 2 diabetes risk, in the section Population science and public health.

  •   Albert Renold Travel Fellowship

    European Foundation for the Study of Diabetes (EFSD)

    Holanda, 2019

    I won this travel grant for a research visit to the Institute of Cardiovascular and Medical Sciences, Universty of Glasgow, UK, in order to work with the UK Biobank cohort, and set a collaboration betwee the research groups of Dr Trudy Voortman and Dr. Carlos Celis-Morales.

  •   Program Doctorado Becas Chile

    ANID

    Chile, 2016

    I received the scholarship Becas Chile to proceed with my PhD Studies at Erasmus University Medical Center.


 

Article (19)

Association of habitual coffee consumption and kidney function: A prospective analysis in the Rotterdam Study
Body Adiposity Partially Mediates the Association between FTO rs9939609 and Lower Adiponectin Levels in Chilean Children
C-reactive protein partially mediates the inverse association between coffee consumption and risk of type 2 diabetes: The UK Biobank and the Rotterdam study cohorts*
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis
Factors associated with healthy aging in Latin American populations
Motivation, barriers and benefits for the practice of physical exercise in a mobile health intervention in adults from Biobio, Chile
The healthy beverage index is not associated with insulin resistance, prediabetes and type 2 diabetes risk in the Rotterdam Study
Dairy Product Consumption in Relation to Incident Prediabetes and Longitudinal Insulin Resistance in the Rotterdam Study
Integrative analysis of clinical and epigenetic biomarkers of mortality
The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis
DNA methylation of blood cells is associated with prevalent type 2 diabetes in a meta-analysis of four European cohorts
Number of years with type 2 diabetes is associated with cognitive impairment in Chilean older adults: A cross-sectional study
Dynamic interventions to control COVID-19 pandemic: a multivariate prediction modelling study comparing 16 worldwide countries
Epigenetic Link Between Statin Therapy and Type 2 Diabetes
Impact of mitigation measures on the COVID-19 pandemic in Chile: preliminary data for the period April 14 to May 14
Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality
Associations of statin use with glycaemic traits and incident type 2 diabetes
Chromatin landscape and epigenetic biomarkers for clinical diagnosis and prognosis of type 2 diabetes mellitus
Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis

Letter (1)

Factores asociados a desarrollo de Diabetes Mellitus tipo II: Evidencia de estudios de randomización mendeliana

Proyecto (8)

The genetic architecture of the human anterior commissure and its role as biomarker of neurodegeneration
Asociación entre variables de salud mental y cognición con la mortalidad por todas las causas en población chilena: un estudio longitudinal.
Association between mental health and cognition with all-cause mortality in the Chilean population: a longitudinal study.
Identification and validation of novel cell-free DNA methylation-based biomarkers for diagnosis of Alzheimer’s disease and frontotemporal dementia progression in blood.
Adaptación y validación del instrumento Nuevo Signo Vital para la alfabetización en salud en pacientes crónicos de la Atención Primaria de Salud (APS)
UCO1201 Diseño e Implementación de un Modelo Territorial Integrado para promoción de estilos de vida saludable y prevención de la obesidad
Posible rol de la actividad Ecto-F1 en la síntesis de NO mediante regulación de la sintasa de óxido nítrico en células HUVEC
Desarrollo de una estrategia territorial integrada transdisciplinaria para prevención de la obesidad en la comunidad escolar

Review (2)

Sexually dimorphic DNA-methylation in cardiometabolic health: A systematic review
Phytoestrogen supplementation and body composition in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials
26
Carolina Ochoa

Investigador

Centro de Vida Saludable

Universidad de Concepción

Rotterdam, Chile

1
Miquel Martorell

Profesor Asociado

Departamento de Nutrición y Dietética

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

1
Gabriela Nazar

Associate Professor

Psychology

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Ximena Díaz

Coordinadora Grupo Investigación

Ciencias de la Educación

Universidad del Bío-Bío

Chillan, Chile

1
Fanny Petermann

Associate Professor

Facultad de Medicina

Universidad Diego Portales

Santiago, Chile

1
Maria Martinez

Profesor Auxiliar

Instituto de Farmacia

Universidad Austral de Chile

Valdivia, Chile

1
Aldo Vera

Investigador

Kinesiología

Universidad de Atacama

Copiapó, Chile

1
Agustin Ibanez

Profesor Titular

Psicologia

Universidad Adolfo Ibánez

Santiago, Chile