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Francisco Ignacio Jaque Fernández

Post-Doctoral Researcher

INSTITUTE NEUROMYOGÈNE CNRS UMR 5310 - INSERM U1217

LYON, Francia

Líneas de Investigación


Excitation-contraction coupling (ECC) using confocal microscopy, calcium dyes, electrophysiology and genetic manipulation. Membrane excitability and ECC in zebrafish or murine models of adult skeletal muscle diseases like Diabetes or Duchenne.

Educación

  •  PhD Physiology, UNIVERSITE CLAUDE BERNARD LYON I. Francia, 2021
  •  Master Physiology, UNIVERSIDAD DE CHILE. Chile, 2016
  •  Physical Therapist, UNIVERSIDAD DE CHILE. Chile, 2012
  •  Ciencias de la Actividad Física , UNIVERSIDAD DE CHILE. Chile, 2013
  •  Ciencias Exactas y Naturales , UNIVERSIDAD DE CHILE. Chile, 2007

Experiencia Académica

  •   practical instructor Musculosquelletical disorders Other

    UNIVERSIDAD DEL DESARROLLO

    Faculty of Medicine

    Santiago, Chile

    2016 - 2017

  •   Academic-researcher Part Time

    UNIVERSITE CLAUDE BERNARD LYON I

    Faculty of Biological Sciences

    LYON, Chile

    2020 - 2021

  •   Assistant teaching Other

    UNIVERSITE CLAUDE BERNARD LYON I

    Faculty of Biological Sciences

    LYON, Chile

    2019 - 2019

  •   Teaching of Cellular Biology Other

    UNIVERSITE CLAUDE BERNARD LYON I

    Faculty of Medicine

    LYON, Chile

    2019 - 2020

  •   Post-Doctoral Researcher Full Time

    UNIVERSITE CLAUDE BERNARD LYON I

    Faculty of Medicine

    LYON, Chile

    2021 - At present

Experiencia Profesional

  •   Physical Therapist (replacement) Full Time

    San José Hospital

    Santiago, Chile

    2013 - 2013

  •   Physical Therapist Part Time

    Clinic ASTRA

    SANTIAGO, Chile

    2014 - 2018

  •   ACADEMIC RESEARCH AND TEACHING POSITION (UNDER TEMPORARY CONTRACT) Part Time

    University Claude Bernard-Lyon1

    LYON, Francia

    2020 - 2021

  •   Post-Doctoral Researcher Full Time

    Institute NeuroMyoGène / University Claude Bernard-Lyon1

    LYON, Chile

    2021 - At present


 

Article (5)

MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis

Ghasemizadeh, Alireza; Christin, Emilie; Guiraud, Alexandre; Couturier, Nathalie; Abitbol, Marie; Risson, Valerie; Girard, Emmanuelle; Jagla, Christophe; Soler, Cedric; Laddada, Lilia; Sanchez, Colline; Jaque-Fernandez, Francisco-Ignacio; Jacquemond, Vincent; Thomas, Jean-Luc; Lanfranchi, Marine; Courchet, Julien; Gondin, Julien; Schaeffer, Laurent; Gache, Vincent

Article ISI
ELIFE  (2021)

Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes

Roberto Silva-Rojas; Vasugi Nattarayan; Francisco Jaque-Fernandez; Raquel Gomez-Oca; Alexia Menuet; David Reiss; Marie Goret; Nadia Messaddeq; Valentina M. Lionello; Christine Kretz; Belinda S. Cowling; Vincent Jacquemond; Jocelyn Laporte

Article
MOLECULAR THERAPY  (2021)

Pannexin-1 and CaV1.1 show reciprocal interaction during excitation-contraction and excitation-transcription coupling in skeletal muscle

Jaque-Fernandez, Francisco; Jorquera, Gonzalo; Troc-Gajardo, Jennifer; Pietri-Rouxel, France; Gentil, Christel; Buvinic, Sonja; Allard, Bruno; Jaimovich, Enrique; Jacquemond, Vincent; Casas, Mariana

Article ISI
JOURNAL OF GENERAL PHYSIOLOGY  (2021)

Preserved Ca2+ handling and excitation-contraction coupling in muscle fibres from diet-induced obese mice

Jaque-Fernandez, Francisco; Beaulant, Agathe; Berthier, Christine; Monteiro, Laloe; Allard, Bruno; Casas, Mariana; Rieusset, Jennifer; Jacquemond, Vincent

Article ISI
DIABETOLOGIA  (2020)

“Estudio piloto de la efectividad de una intervención basada en juegos sobre el estado nutricional y la fuerza muscular en niños”

Johana Patricia Soto-Sánchez, Javier Ignacio Bravo-Gatica; Alan Rigoberto White Ortiz, Francisco Ignacio Jaque Fernández; Cristian Ignacio Vargas-Gyllen, Sandra Arriagada Cárdenas; Fernando Carrasco Naranjo, Marcelo Antonio Cano-Cappellacci

Article
Nutrición hospitalaria  (2014)

Proyecto (2)

Identificar candidatos a fármacos pertenecientes a la familia de las dihidropiridinas (DHP) para el tratamiento de la Sarcopenia y la distrofia muscular

FONDEF (ID16I10101)

Proyecto
2017-2018
Personal técnico y/o de apoyo

Purinergic signaling in the adult muscle fiber=> functional crosstalk with the inositol phosphate pathway.

PCI (C13B01)

Proyecto
2014-2016
Tesista

4
Francisco Jaque

Post-Doctoral Researcher

INSTITUTE NEUROMYOGÈNE CNRS UMR 5310 - INSERM U1217

LYON, Francia

1
Sonja Buvinic

Associate Professor

Institute for Research in Dental Sciences

Universidad de Chile

Santiago, Chile

1
Jennifer Troc

Gestora Tecnológica

Vicerrectoria de Investigación y doctorados

Universidad Autónoma de Chile

Talca, Chile