Man

Isis Trujillo-González

Research assistant professor

University of North Carolina

Charlotte , Estados Unidos

Líneas de Investigación


Nutritional neuroscience and epigenetics, centered on one-carbon metabolism, choline biology, and the developmental origins of neurological and metabolic disease.

Educación

  •  Biomedical Sciences, UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO. México, 2014

Experiencia Académica

  •   Graduate Research Associate Full Time

    UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO

    México

    2009 - 2014

  •   Postdoctoral Research Associate Full Time

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    Estados Unidos

    2015 - 2020

  •   Research Assistant Professor Full Time

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    Estados Unidos

    2021 - At present

  •   Animal Metabolism Phenotyping Core (NORC) Full Time

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    Chile

    2025 - At present

Experiencia Profesional

  •   Research assistant professor Full Time

    University of North Carolina

    Estados Unidos

    2021 - At present

  •   Co-Director, Animal Metabolism Phenotyping Core (NORC) Full Time

    University of North Carolina

    Chile

    2025 - At present

Premios y Distinciones

  •   Impact Award for Cultural Stewardship

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    Estados Unidos

    Impact Award for Cultural Stewardship, Nutrition Research Institute, UNC Chapel Hill

  •   Poster Competition Winner (Postdoctoral Level)

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    Chile

    Poster Competition Winner (Postdoctoral Level), NIH Precision Nutrition Workshop.

  •   1st Place, Best Postdoctoral Researcher Poster

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    España

    1st Place, Best Postdoctoral Researcher Poster, 12th International FASEB Conference on One Carbon Metabolism, Catalunya, Spain.

  •   Graduate Student Travel Award

    UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

    Estados Unidos

    American Society of Human Genetics Annual Meeting


 

Article (13)

Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study

Trujillo-Gonzalez, Isis; Horita, David A.; Stegall, Julie; Coble, Rachel; Paules, Evan M.; Lulla, Anju A.; Baah, Emmanuel; Bottiglieri, Teodoro; Sha, Wei; Kohlmeier, Martin; et al.

Article ISI
AMERICAN JOURNAL OF CLINICAL NUTRITION  (2026)

Future Directions in Choline: From Neurodevelopment to Cardiometabolic Health

Paules, Evan M.; Petry, Hannah G.; Sprinkles, Jessica K.; Trujillo-Gonzalez, Isis

Article ISI
NUTRIENTS  (2025)

Sex-specific systemic metabolic predictors of resistance to calorie restriction-induced weight loss in obese diversity outbred mice

Paules, Evan M.; Verhague, Melissa; Lulla, Anju A.; Meyer, Katie A.; Coleman, Michael F.; Albright, Jody; Bennett, Brian J.; North, Kari E.; Howard, Annie Green; Gordon-Larsen, Penny; et al.

Article ISI
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY  (2025)

Urinary signatures are associated with calorie restriction-mediated weight loss in obese Diversity Outbred mice

Paules, Evan M.; Trujillo-Gonzalez, Isis; Verhague, Melissa; Albright, Jody; Stewart, Delisha; Sumner, Susan J.; McRitchie, Susan L.; Kirchner, David; Coleman, Michael F.; Bennett, Brian J.; et al.

Article ISI
PLOS ONE  (2025)

Choline Metabolites and 15-Year Risk of Incident Diabetes in a Prospective Cohort of Adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study

Sprinkles, Jessica K.; Lulla, Anju; Hullings, Autumn G.; Trujillo-Gonzalez, Isis; Klatt, Kevin C.; Jacobs, David R.; Shah, Ravi, V; Murthy, Venkatesh L.; Howard, Annie Green; Gordon-Larsen, Penny; et al.

Article ISI
DIABETES CARE  (2024)

Choline metabolites and incident cardiovascular disease in a prospective cohort of adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study

Shea, Jonathan W.; Jacobs Jr, David R.; Howard, Annie Green; Lulla, Anju; Lloyd-Jones, Donald M.; Murthy, Venkatesh L.; Shah, Ravi, V; Trujillo-Gonzalez, Isis; Gordon-Larsen, Penny; Meyer, Katie A.

Article ISI
AMERICAN JOURNAL OF CLINICAL NUTRITION  (2024)

Editorial: Leveraging multi-omics approaches to understand and manage gastrointestinal and hepatic diseases

Trujillo-Gonzalez, Isis; Thomes, Paul G.; Sakallioglu, Isin Tuna; Kharbanda, Kusum K.

Article ISI
FRONTIERS IN PHARMACOLOGY  (2024)

Choline Regulates SOX4 through miR-129-5p and Modifies H3K27me3 in the Developing Cortex

Paules, Evan M.; Silva-Gomez, Jorge A.; Friday, Walter B.; Zeisel, Steve H.; Trujillo-Gonzalez, Isis

Article ISI
NUTRIENTS  (2023)

Homocysteine-induced endoplasmic reticulum stress activates FGF21 and is associated with browning and atrophy of white adipose tissue in<i> Bhmt</i> knockout mice

Warrier, Manya; Paules, Evan M.; Silva-Gomez, Jorge; Friday, Walter B.; Bramlett, Frances; Kim, Hyunbae; Zhang, Kezhong; Trujillo-Gonzalez, Isis

Article ISI
HELIYON  (2023)

Low availability of choline <i>in utero</i> disrupts development and function of the retina

Trujillo-Gonzalez, Isis; Friday, Walter B.; Munson, Carolyn A.; Bachleda, Amelia; Weiss, Ellen R.; Alam, Nazia M.; Sha, Wei; Zeisel, Steven H.; Surzenko, Natalia

Article ISI
FASEB JOURNAL  (2019)

MicroRNA-129-5p is regulated by choline availability and controls EGF receptor synthesis and neurogenesis in the cerebral cortex

Trujillo-Gonzalez, Isis; Wang, Yanyan; Friday, Walter B.; Vickers, Kasey C.; Toth, Cynthia L.; Molina-Torres, Lorian; Surzenko, Natalia; Zeisel, Steven H.

Article ISI
FASEB JOURNAL  (2019)

Holocarboxylase synthetase acts as a biotin-independent transcriptional repressor interacting with HDAC1, HDAC2 and HDAC7

Trujillo-Gonzalez, Isis; Cervantes-Roldan, Rafael; Gonzalez-Noriega, Alfonso; Michalak, Colette; Reyes-Carmona, Sandra; Barrios-Garcia, Tonatiuh; Meneses-Morales, Ivan; Leon-Del-Rio, Alfonso

Article ISI
MOLECULAR GENETICS AND METABOLISM  (2014)

SIP1/NHERF2 enhances estrogen receptor alpha transactivation in breast cancer cells

Meneses-Morales, Ivan; Tecalco-Cruz, Angeles C.; Barrios-Garcia, Tonatiuh; Gomez-Romero, Vania; Trujillo-Gonzalez, Isis; Reyes-Carmona, Sandra; Garcia-Zepeda, Eduardo; Mendez-Enriquez, Erika; Cervantes-Roldan, Rafael; Perez-Sanchez, Victor; et al.

Article ISI
NUCLEIC ACIDS RESEARCH  (2014)

Review (2)

Myokines and Their Potential Protective Role Against Oxidative Stress in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Trujillo-Gonzalez, Isis; Paules, Evan M.

Review ISI SCOPUS
Antioxidants  (2024)

The role of prenatal choline and its impact on neurodevelopmental disorders

Mujica-Coopman, Maria F.; Paules, Evan M.; Trujillo-Gonzalez, Isis

Review ISI SCOPUS
Frontiers in Nutrition  (2024)

1
Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

1
MARIA MUJICA

Profesora asistente

Instituto de Nutrición y Tecnología de los alimentos (INTA)

Universidad de Chile

Santiago, Chile

15
Isis Trujillo-González

Research assistant professor

University of North Carolina

Charlotte , Estados Unidos