Man

Francisco Andres Silva Labra

Assistant Professor

Pontificia Universidad Catolica de Chile

Santiago, Chile

Líneas de Investigación


Autoimmune diseases Immune suppressants - Biological therapy Systemic Vasculitis Rheumatoid Arthritis

Educación

  •  Clinical Science - Biomedical Sciences, MAYO CLINIC FOUNDATION. Estados Unidos, 2010
  •  Rheumatology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2003
  •  Internal Medicine, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2001
  •  MD, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1997

Experiencia Académica

  •   Assistant Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicine

    Santiago, Chile

    2011 - A la fecha

  •   Instructor in Medicine Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicine

    Santiago, Chile

    2003 - 2011

Experiencia Profesional

  •   Rheumatologist Full Time

    Pontificia Universidad Catolica de Chile

    Santiago, Chile

    2006 - A la fecha

  •   Rheumatologist Part Time

    Pontificia Universidad Catolica de Chile

    Santiago, Chile

    2003 - 2006

  •   Rheumatologist Part Time

    Hospital Dr. Sotero del Rio

    Santiago, Chile

    2003 - 2006

  •   Internal Medicine - Emergency Room Part Time

    Pontificia Universidad Catolica de Chile

    Santiago, Chile

    2001 - 2003

Formación de Capital Humano


Undergraduate students.
- Tutorial of undergraduate medical students in the Course Medical Semiology ( Third year of Medicine, Pontificia Universidad Catolica de Chile / MEC 231-A), 96 hours per year, every two years since 2003.
-Tutorial of undergraduate medical students in the Course of Rheumatology ( Fourth year of Medicine, Pontificia Universidad Catolica de Chile / MEQ 246) and Fourth and Fifth year of Medicine, Pontificia Universidad Catolica de Chile, 9 hours every year since 2003.
- Tutorial activities of medical students ( Fourth year , 80 hours , Outpatient clinic )
- Training activities of post - graduate students, including Residents of Rheumatology and Internal Medicine, 96 hours every year, Hospital Clínico P. U. Católica, since 2006.

Post graduate students
- Thesis Director of the Internal Medicine Thesis of Dr. Milena Mimica : "Response to Rituximab In patients with vasculitis associated to ANCA: Experience of 5 years in a tertiary center in Chile. Hospital Clínico P. U. Católica. 2011
- Tutorial of seminars of Internal Medicine Residents, ( "Vasculitis", "Gout" ), Hospital Clínico Pontificia Universidad Católica de Chile, 2012 ; 2013.
- Class in the Biology Course BIO389E, "Bases Moleculares de las Vasculitis, Faculty of Biological Sciences, 2012 ; 2013.
- Professor of Section Curso MEN202-A, Second year of Nutrition Career. 2014


Premios y Distinciones

  •   Tercer Premio Sociedad Chilena de ReumatologÌa

    SOCIEDAD CHILENA DE REUMATOLOGIA

    Chile, 2011

    Third place for the participation in the XXVIII Congreso Chileno de ReumatologÌa, Antofagasta, Chile, with the study "Respuesta a Rituximab en pacientes con vasculitis. Experiencia a 5 aÒos en un centro terciario de salud " by the authors P Pastenes, L Massardo, F Silva, M Cisternas, F Radrigan and MA Gutierrez in Antofagasta, Chile

  •   Tercer Premio Grupo Latinoamericano de EspondiloartropatÌas

    GRUPO LATINOAMERICANO DE ESPONDILOARTROPATIA

    Colombia, 2005

    Third place in the "1er Congreso de Espondiloartropatía", Colombia with the study "Psoriatic Arthritis: a clinical analysis of 80 Chilean patients Silva F., Gutiérrez F., Rubio R., Salinas J., Radrigán F., Gutiérrez M. Hospital Dr. Sótero del Río y Pontificia Universidad Católica de Chile.

  •   Primer Premio Sociedad Chilena de Reumatología

    SOCIEDAD CHILENA DE REUMATOLOGIA

    Chile, 2002

    First place of the Sociedad Chilena de Reumatología, for the study " Función del Eje Hipotálamo - Hipófisis - Suprarenal y su relación con genotipo HLADR4 en Artritis Reumatoídea Activa", F Silva, MA Gutiérrez, L Llanos, N Molina, P García, C Campusano, S Jacobelli. P.U.Católica de Chile


 

Article (7)

A Monoclonal Antibody (MCPR3-7) Interfering with the Activity of Proteinase 3 by an Allosteric Mechanism

Hinkofer, L. C.; Seidel, S. A. I.; Korkmaz, B.; Silva, F; Hummel, A. M.; Braun D.; Jenne, D. E.; Specks, U

Article ISI SCOPUS
Journal of Biological Chemistry  (2013)

TNF-? Blocker Therapy and Solid Malignancy Risk in ANCA-Associated Vasculitis

Silva, F; Cisternas,M; Specks, U

Article
CURRENT RHEUMATOLOGY REPORTS  (2012)

Solid Malignancies Among Etanercept-Treated Patients With Granulomatosis With Polyangiitis (Wegener's) Long-Term Followup of a Multicenter Longitudinal Cohort

Silva, F; Seo, P.; Schroeder, DR; Stone, JH; Merkel, PA; Hoffman, GS; Spiera, R; Sebastian, JK; Davis, JC; St Clair, EW; et al.

Article ISI SCOPUS
Arthritis and Rheumatism  (2011)

Discrimination and variable impact of ANCA binding to different surface epitopes on proteinase 3, the Wegener's autoantigen

Silva, Francisco; Hummel, Amber M.; Jenne, Dieter E.; Specks, Ulrich

Article ISI
JOURNAL OF AUTOIMMUNITY  (2010)

Mycophenolate Mofetil for Induction and Maintenance of Remission in Microscopic Polyangiitis with Mild to Moderate Renal Involvement-A Prospective, Open-Label Pilot Trial

Silva, F; Specks, U; Kalra, S.; Hogan, M. C.; Leung, N.; Sethi S.

Article ISI
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY  (2010)

Successful Pregnancy and Delivery of a Healthy Newborn Despite Transplacental Transfer of Antimyeloperoxidase Antibodies From a Mother With Microscopic Polyangiitis

Silva, Francisco; Specks, Ulrich; Sethi, Sanjeev; Irazabal, Maria Valentina; Fervenza, Fernando C.

Article
American Journal of Kidney Diseases  (2009)

RESPONDIA. Iberoamerican Spondyloarthritis Registry: Chile Registro Iberoamericano de Espondiloartritis (RESPONDIA): Chile

Gutiérrez M.A.; Pérez, C.; Silva, F; Elgueta K.; Rosas, M; Saavedra J.; Fuentealba, C; Pozo, P; Neira Ó; Kusnir, P; et al.

Article SCOPUS
Reumatologia Clinica Suplementos  (2008)

Abstract (3)

IgA-ANCA in WG

Nelson, DR; Hummel, AM; Silva, F; Schroeder, D; Stone, JH; Hoffman, GS; Merkel, PA; Monach, PA; Spiera, RF; St Clair, EW; et al.

Abstract
CLINICAL AND EXPERIMENTAL IMMUNOLOGY  (2011)

Sensitivity analysis of multi-modality ANCA testing under controlled conditions

Silva, F; Nelson, DR; Hummel, AM; Schroeder, DR; Snyder, MR; Specks, U

Abstract
CLINICAL AND EXPERIMENTAL IMMUNOLOGY  (2011)

Function of the hypothalamic-pituitary-adrenucortical axis and its relationship with HLA-DR genotype in women with early rheumatoid arthritis and first grade relatives

Silva, F; LLanos, L; Campusano, C; Vargas A.; Jacobelli, S.; Kalergis, A; Chávez A.

Abstract
ANNALS OF THE RHEUMATIC DISEASES  (2007)

Review (2)

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis: advances in pathogenesis and treatment

Silva, F; Cisternas,M

Review
REVISTA MEDICA DE CHILE  (2013)

Vasculitis asociadas a anticuerpos anti-citoplasma de neutrófilos: avances en patogenia y tratamiento

Silva, Francisco; Cisternas, Marcela

Review SCIELO SCOPUS
REVISTA MEDICA DE CHILE  (2013)

12
Francisco Silva

Assistant Professor

Clinical Immunology and Rheumatology

Pontificia Universidad Catolica de Chile

Santiago, Chile