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Mikko Eemil Karttunen -

Full Professor

University of Waterloo

Waterloo, Canada

Líneas de Investigación


Computational & theoretical soft matter and biological physics, computational chemistry, statistical mechanics

Educación

  •  Physics, MCGILL UNIVERSITY. Canada, 1999
  •  Engineering Physics, TAMPERE UNIVERSITY OF TECHNOLOGY. Finlandia, 1993

Experiencia Académica

  •   Professor Full Time

    UNIVERSITY OF WATERLOO

    Science

    Waterloo, Canada

    2011 - A la fecha

  •   Associate Professor Full Time

    UNIVERSITY OF WESTERN ONTARIO

    Science

    London, Canada

    2008 - 2011

  •   Assistant Professor Full Time

    UNIVERSITY OF WESTERN ONTARIO

    Science

    London, Canada

    2006 - 2008

  •   Academy of Finland Research Fellow Full Time

    Helsinki University of Technology

    Helsinki, Finlandia

    2003 - 2005

  •   Lecturer and project leader Full Time

    HELSINKI UNIVERSITY OF TECHNOLOGY

    Helsinki, Finlandia

    2000 - 2003

  •   Postdoctoral fellow Full Time

    MAX-PLANCK INSTITUT FUR POLYMERFORSCHUNG

    Mainz, Alemania

    1999 - 2000

Experiencia Profesional

  •   Full Professor Full Time

    University of Waterloo

    Waterloo, Canada

    2011 - A la fecha

  •   Associate Professor Full Time

    University of Western Ontario

    London, Canada

    2008 - 2011

  •   Assistant Professor Full Time

    University of Western Ontario

    London, Canada

    2006 - 2008

  •   Academy of Finland Fellow Full Time

    Helsinki University of Technology

    Helsinki, Finlandia

    2003 - 2005

  •   Lecturer and project leader Full Time

    Helsinki University of Technology

    Helsinki, Finlandia

    2000 - 2003

  •   Postdoctoral Fellow Full Time

    Max Planck Institute for Polymer Research

    Mainz, Alemania

    1999 - 2000

Formación de Capital Humano


Post-doctoral:

Dr. Drew Bennett, 08/13-current (NSERC Sir Frederic Banting Fellow, Canada’s top post- doctoral fellowship. About 25 is granted annually in all of science and engineering in Canada)
Dr. Trang Do, 02/13-current
Dr. John Titantah, 12/09-12/14.
Dr. Matt Hoopes, 09/11-09/13.
Dr. Jari Jalkanen, 06/10-11/12 (jointly with Dr. G. Hunter and Dr. H. Goldberg).
Dr. Hector Martinez, 1/10-7/11 (awareded Academy of Finland Postdoctoral Fellowship for this work)
Dr. Jirasak Wong-Ekkabut, 1/08-12/09
Dr. Cristiano Dias, 11/07-10/09
Dr. Andrea Catte, 1/07-12/08.
Dr. Pawel Pomorski, 1/2006-2/2008.
Dr. Jarmila Repakova, 5/2005-5/2007 (jointly with Dr. Ilpo Vattulainen).
Dr. Tomasz Róg, 9/2004-7/2008; European Union Marie Curie fellow.
Dr. Lorna Stimson, 9/2004-9/2007
Dr. Michael Patra, European Union Marie Curie fellow; 9/2001-11/2004.

17 Graduate thesis supervised. These students have become professors, industrial researchers and have received top scholarships in Europe, Asia and Canada.

Currently: 6 PhD students under supervision, 2 of them are co-supervised.
Since 2009: 6 visiting students hosted from Hong Kong, Thailand, Italy, Finland and China.


Premios y Distinciones

  •   NSERC Discovery Accelerator Supplement (DAS) Award

    NATIONAL RESEARCH COUNCIL OF CANADA

    Canada, 2009

    NSERC Discovery Accelerator Supplement (DAS) Award. A total of $120,000.

  •   Faculty of Science Distinguished Research Professor

    UNIVERSITY OF WESTERN ONTARIO

    Canada, 2009

    Award to the top scientist in the faculty

  •   The Ontario Early Researcher Award

    The Province of Ontario

    Chile, 2008

    Award worth $150,000 to top young scientists in the Province of Ontario (Canada's largest and most populous province)

  •   DEISA European Union High Performance Computing Award

    EUROPEAN UNION

    Holanda, 2007

    DEISA = Distributed European Infrastructure for Supercomputing Applications (www.deisa.org). Our consortium, myself, I. Vattulainen (Tampere Univ. of Tech., Finland), M. Hyvönen (Wihuri Research Inst. Helsinki, Finland), and. S.J. Marrink (Groningen Univ., the Netherlands) was awarded 700,000 cpu-hours (or 80 cpu years) on Europe’s fastest computers to study the ’bad’ (LDL) cholesterol. DEISA/DECI European Union projects (direct quote): "This initiative consists of the identification, enabling, deploying and operating flagship applications in selected areas of science and technology. These leading, ground breaking applications must deal with complex, demanding, innovative simulations that would not be possible without the DEISA infrastructure, and which would benefit – if accepted – from the exceptional resources of the Consortium."


 

Article (95)

A new model for cell division and migration with spontaneous topology changes
Biopolymer Filtration in Corrugated Nanochannels
Classical Electrostatics for Biomolecular Simulations
Dehydroergosterol as an Analogue for Cholesterol: Why It Mimics Cholesterol So Well—or Does It?
Effect of melatonin and cholesterol on the structure of DOPC and DPPC membranes
In situ nanoparticle size measurements of gas-borne silicon nanoparticles by time-resolved laser-induced incandescence
Modeling the behavior of confined colloidal particles under shear flow
Molecular Dynamics Simulations of DPPC/CTAB Monolayers at the Air/Water Interface
Molecular dynamics simulations of lipid membranes with lateral force: Rupture and dynamic properties
Molecular dynamics study of DNA oligomers under angled pulling
Porphyrin–phospholipid liposomes permeabilized by near-infrared light
Analytical model and multiscale simulations of Aβ peptide aggregation in lipid membranes: towards a unifying description of conformational transitions, oligomerization and membrane damage
Binding of disordered proteins to a protein hub
Conformational Biases of Linear Motifs
Early stages of interactions of cell-penetrating peptide penetratin with a DPPC bilayer
Hydrodynamic effects on confined polymers
Melatonin directly interacts with cholesterol and alleviates cholesterol effects in dipalmitoylphosphatidylcholine monolayers
Molecular Dynamic Studies of Transportan Interacting with a DPPC Lipid Bilayer
Molecular Dynamics Study of Oxidized Lipid Bilayers in NaCl Solution
Multiphase density functional theory parameterization of the interatomic potential for silver and gold
Phase-field-crystal model for magnetocrystalline interactions in isotropic ferromagnetic solids
Pulling of double-stranded DNA by atomic force microscopy: a simulation in atomistic details
Thermal accommodation coefficients for laser-induced incandescence sizing of metal nanoparticles in monatomic gases
Water dynamics: Relation between hydrogen bond bifurcations, molecular jumps, local density & hydrophobicity
α-Helical Structures Drive Early Stages of Self-Assembly of Amyloidogenic Amyloid Polypeptide Aggregate Formation in Membranes
A molecular dynamics implementation of the 3D Mercedes-Benz water model
Assessment of Common Simulation Protocols for Simulations of Nanopores, Membrane Proteins, and Channels
Cationic Dimyristoylphosphatidylcholine and Dioleoyloxytrimethylammonium Propane Lipid Bilayers: Atomistic Insight for Structure and Dynamics
Combined depletion and electrostatic forces in polymer-induced membrane adhesion: A theoretical model
Comparison of Secondary Structure Formation Using 10 Different Force Fields in Microsecond Molecular Dynamics Simulations
Effects of Molecular Crowding on the Dynamics of Intrinsically Disordered Proteins
Long-Time Correlations and Hydrophobe-Modified Hydrogen-Bonding Dynamics in Hydrophobic Hydration
Mechanism of inhibition of calcium oxalate crystal growth by an osteopontin phosphopeptide
Mimicking the Biomolecular Control of Calcium Oxalate Monohydrate Crystal Growth: Effect of Contiguous Glutamic Acids
Molecular dynamics simulation of thermal accommodation coefficients for laser-induced incandescence sizing of nickel particles
Molecular Dynamics Simulations of the Bacterial ABC Transporter SAV1866 in the Closed Form
Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase
Stiffness transition in anisotropic fiber nets
A study of the surface structure of the PEGylated liposome in physiological conditions using all atom molecular dynamics simulation and Langmuir monolayer studies
Citrate Modulates Calcium Oxalate Crystal Growth by Face-Specific Interactions
Electrostatics in biomolecular simulations: Where are we now and where are we heading
Fluctuating lattice-Boltzmann model for complex fluids
Hydrophobic interactions in the formation of secondary structures in small peptides
Hydrophobicity within the three-dimensional Mercedes-Benz model: Potential of mean force
Lipid domain morphologies in phosphatidylcholine-ceramide monolayers
Low density lipoprotein: structure, dynamics, and interactions of apoB-100 with lipids
Matrix Gla Protein Inhibits Ectopic Calcification by a Direct Interaction with Hydroxyapatite Crystals
Microsecond Molecular Dynamics Simulations of Intrinsically Disordered Proteins Involved in the Oxidative Stress Response
Simulations of Micellization of Sodium Hexyl Sulfate
Ab initio simulations of peptide-mineral interactions
Cholesterol Off-Plane Methyl Groups Induce Formation of Cholesterol-Rich Domains and Quasi-Long-Range Lateral Order in Cholesterol/Phospholipid Membranes
Cutting Ice: Nanowire Regelation
Myosin motor mediated contraction is enough to produce cytokinesis in the absence of polymerisation
Phosphorylation of Ser 136 is critical for potent bone sialoprotein-mediated nucleation of hydroxyapatite crystals
Role of Lipids in Spheroidal High Density Lipoproteins
Roles of Electrostatics and Conformation in Protein-Crystal Interactions
Static charges cannot drive a continuous flow of water molecules through a carbon nanotube
The Flexible Polyelectrolyte Hypothesis of Protein−Biomineral Interaction
The hydrophobic effect and its role in cold denaturation
Aster formation and rupture transition in semi-flexible fiber networks with mobile cross-linkers
Effects of the lipid bilayer phase state on the water membrane interface
he Role of Glycolipids in Lipid Rafts: A View through Atomistic Molecular Dynamics Simulations with Galactosylceramide
Ion Dynamics in Cationic Lipid Bilayer Systems in Saline Solutions
Ionic Surfactant Aggregates in Saline Solutions: Sodium Dodecyl Sulfate (SDS) in the Presence of Excess Sodium Chloride (NaCl) or Calcium Chloride (CaCl 2 )
Mitochondrial Membranes with Mono- and Divalent Salt: Changes Induced by Salt Ions on Structure and Dynamics
Molecular dynamics study of prolyl oligopeptidase with inhibitor in binding cavity
Multiscale modeling of emergent materials: biological and soft matter
Nonlinear driven response of a phase-field crystal in a periodic pinning potential
Ordering effects of cholesterol and its analogues
Phosphorylation of Osteopontin Peptides Mediates Adsorption to and Incorporation into Calcium Oxalate Crystals
Systematic coarse graining from structure using internal states: Application to phospholipid/cholesterol bilayer
Three-dimensional “Mercedes-Benz” model for water
Agent-Based Modelling of Glucose Transport
Comparison of cholesterol and its direct precursors along the biosynthetic pathway: Effects of cholesterol, desmosterol and 7-dehydrocholesterol on saturated and unsaturated lipid bilayers
Dynamical scaling exponents for polymer translocation through a nanopore
Influence of cis double bond parameterization on lipid membrane properties: How seemingly insignificant details in force change even qualitative trends
Influence of Ethanol on Lipid Membranes:  From Lateral Pressure Profiles to Dynamics and Partitioning
Interplay of Unsaturated Phospholipids and Cholesterol in Membranes: Effect of the Double-Bond Position
Lateral Diffusion in Lipid Membranes through Collective Flows
Micelle Fission through Surface Instability and Formation of an Interdigitating Stalk
Microscopic Mechanism for Cold Denaturation
Molecular dynamics simulations of the enzyme Catechol-O-Methyltransferase: methodological issues1
Nonpolar interactions between trans-membrane helical EGF peptide and phosphatidylcholines, sphingomyelins and cholesterol. Molecular dynamics simulation studies
Phase diagram of pinned lattices in the phase field crystal model
Replacing the Cholesterol Hydroxyl Group with the Ketone Group Facilitates Sterol Flip-Flop and Promotes Membrane Fluidity
Role of cardiolipins in the inner mitochondrial membrane: insight gained through atom-scale simulations
Role of phosphatidylglycerols in the stability of bacterial membranes
Significance of Cholesterol Methyl Groups
Strain hardening, avalanches, and strain softening in dense cross-linked actin networks
Structure of Spheroidal HDL Particles Revealed by Combined Atomistic and Coarse-Grained Simulations
Water isotope effect on the bilayer properties: a molecular dynamics simulation study
Why the sn-2 chain of monounsaturated glycerol-phospholipids is usually unsaturated while the sn-1 chain is saturated? Studies of SOPC and OSPC membranes with and without cholesterol
Anomalously slow phase transitions in self-gravitating systems
Collapses and explosions in self-gravitating systems
A new model for cell division and migration with spontaneous topology changes

Proyecto (6)

Modelling self-assembly & dynamics of biophysical & soft matter
De- sign and screening of DNA-functionalized hydrogels for contaminants in water
Light-triggered drug release in pancreatic tumors
University of Waterloo startup
Natural Sciences and Engineering Council of Canada (NSERC) Discovery Accelerator Supplement Award
Self-assembly and dynamics in biomaterials and biological matter
1
Yaroslav Ispolatov

Associate professor

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

101
Mikko Karttunen

Full Professor

Chemistry

University of Waterloo

Waterloo, Canada