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Paula Carolina Díaz Rodríguez

Assistant Professor

UNIVERSIDAD MAYOR

Santiago, Chile

pregnancy; maternal health; precancerous lesions

Licenciado en Tecnología Médica, UNIVERSIDAD DE CHILE. Chile, 2004
Magíster en Ciencias Biológicas mención Biología Celular, UNIVERSIDAD DE CHILE. Chile, 2007
Medicine PhD - Human Development, THE UNIVERSITY OF MANCHESTER. Reino Unido, 2013
Tecnólogo Médico mención Morfofisiopatología y Citodiagnóstico, UNIVERSIDAD DE CHILE. Chile, 2004
Diplomado en Bioinformática y Biología Computacional, UNIVERSIDAD DE CHILE. Chile, 2019

Postdoctoral Research Associate Full Time

UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO

San Antonio, Texas, Estados Unidos

2014 - 2014
Postdoctoral Research Associate Full Time

UNIVERSITY OF COLORADO DENVER

Aurora, Colorado, Estados Unidos

2014 - 2015
Postdoctoral Research Fellow Full Time

UNIVERSIDAD DE CHILE

Medicine

Santiago, Chile

2015 - 2021
Assistant Professor Full Time

UNIVERSIDAD MAYOR

Facultad de Medicina y Ciencias de la Salud

Santiago, Chile

2024 - A la fecha

Coordinadora interina mención Morfofisiopatología y Citodiagnóstico Part Time

Universidad Mayor

Santiago, Chile

2009 - 2009
Coordinadora de Investigación y Postgrado Facultad de Salud Full Time

Universidad Santo Tomás

Santiago, Chile

2021 - 2024

· Monitor at XXIV National Week of Science and Technology – EXPLORA – Center for Exercise, Metabolism and Cancer Studies – Laboratory showcase for secondary school students (October 2018). Universidad de Chile, Santiago, Chile
· Scientific Reviewer at XII Regional Secondary School Conference EXPLORA – Ministry of Science, Technology, Knowledge and Innovation (October 2017). Universidad de Chile, Santiago, Chile
· Monitor at Open Laboratories – Postgraduate Winter School – An activity for young Latin-American researchers (July 2017). Universidad de Chile, Santiago, Chile
· Participation at showcase of Faculty of Medical and Human Sciences, “Circle of Friends” – Presentation and description of student experience and overview of PhD research project to groups of International Educational Consultant delegates (June 2013). University of Manchester, Manchester, UK

New Investigator Travel Award

NATIONAL INSTITUTES OF HEALTH (NIH)

Estados Unidos, 2013

At the Aspen/Snowmass Perinatal Biology Symposium, Snowmass Village, CO, USA (August 2013)
Y. W. Loke New Investigator Travel Award

International Federation of Placenta Associations (IFPA)

Noruega, 2011

In recognition of the excellence of the abstract submitted for the 17th IFPA meeting, Geilo, Norway (September 2011)
The Giorgio Pardi Foundation Award

Society for Reproductive Investigation (SRI)

Estados Unidos, 2011

Research award (US$2000) funded by the Giorgio Pardi Foundation. In recognition of highly meritorious abstract in the field of fetal and placental function submitted by individuals still in training, SRI, Miami, FL, USA (March 2011)


Helicobacter Pylori Infection Triggers PERK-Associated Survivin Loss in Gastric Tissue Samples and Cell Lines Article CROSSREF Journal of Cancer Science and Clinical Therapeutics (2021)
Helicobacter pylori Outer Membrane Vesicles and Extracellular Vesicles from Helicobacter pylori-Infected Cells in Gastric Disease Development Diaz, Paula; Herrera, Daniela Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Perspectives on Organelle Interaction, Protein Dysregulation, and Cancer Disease Diaz, Paula Article ISI FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response Diaz, Paula; Ortiz, Rina Article ISI CELL DEATH & DISEASE (2020)
A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells Bravo; Quest Article ISI SCOPUS CANCERS (2019)
Calcium Transport and Signaling in Mitochondria Article ISI SCOPUS COMPREHENSIVE PHYSIOLOGY (2017)
Glyburide treatment in gestational diabetes is associated with increased placental glucose transporter 1 expression and higher birth weight Dimasuay, KG; Koele-Schmidt, L; Jang, B; Barbour, LA; Powell, TL Article ISI PLACENTA (2017)
Oxygen-Sensitive K+ Channels Modulate Human Chorionic Gonadotropin Secretion from Human Placental Trophoblast Diaz, Paula; Sibley, Colin P.; Greenwood, Susan L. Article ISI PLOS ONE (2016)
Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy Diaz, Paula; Harris, Jessica; Rosario, Fredrick J.; Powell, Theresa L.; Jansson, Thomas Article ISI AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2015)
Na+, K+-ATPase and Ca2+-ATPase activities in basal and microvillous syncytiotrophoblast membranes from preeclamptic human term placenta Abad C.; Vallejos C.; De Gregorio, N; Díaz P; Mendoza M.; Pinero S.; Proverbio T.; Botana D.; Rojas P.; RIQUELME, G; et al. Article ISI SCOPUS Hypertension in Pregnancy (2015)
Intermediate Conductance Ca2+-Activated K+ Channels Modulate Human Placental Trophoblast Syncytialization Diaz, Paula; Wood, Amber M. Article ISI PLOS ONE (2014)
The Role of Placental Nutrient Sensing in Maternal-Fetal Resource Allocation Diaz, Paula Article ISI BIOLOGY OF REPRODUCTION (2014)
IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta Ahmed, M. S.; Aleksunes, L. M.; Boeuf, P.; Chung, M. K.; Daoud, G.; Desoye, G.; Golos, T. G.; Illsley, N. P.; Kikuchi, K.; Lao, T.; et al. Article ISI PLACENTA (2013)
Expression and Distribution of Nucleoside Transporter Proteins in the Human Syncytiotrophoblast Errasti-Murugarren, E; Díaz P; Godoy, V; RIQUELME, G; Pastor-Anglada, M Article ISI SCOPUS Molecular Pharmacology (2011)
Barium, Tea and Sodium Sensitive Potassium Channels are Present in the Human Placental Syncytiotrophoblast Apical Membrane Díaz P; Vallejos C.; Guerrero, I.; RIQUELME, G Article ISI SCOPUS PLACENTA (2008)
Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta Marín R.; RIQUELME, G; Godoy, V; Díaz P; Abad C.; Caires, R; Proverbio T.; Pinero S.; Proverbio, F Article ISI SCOPUS PLACENTA (2008)
Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane Bernucci L; Henriquez, M.; Díaz P; RIQUELME, G Article ISI SCOPUS PLACENTA (2006)


IFPA Meeting 2010 Workshop Report I: Immunology; Ion transport; Epigenetics; Vascular reactivity; Epitheliochorial placentation; Proteomics Abad C.; Marín R.; Antczak D.F.; Carvalho J.; Chen, Q; Daher S; Damiano A.E.; Dantzer V; Díaz P; Harris L.K.; et al. EditorialMaterial ISI SCOPUS Placenta (2011)


THE ROLE OF PKR-LIKE ER KINASE (PERK) IN HELICOBACTER PYLORI INDUCED GASTRIC CELL DEATH AND PROGRESSION OF PRECANCEROUS LESIONS TO GASTRIC CANCER FONDECYT (3170140) Proyecto 2017-2020 Inv. Responsable
PREECLAMPSIA Y LIPIDOS RAFT=> MECANISMOS DE TRANSPORTE PLACENTARIO, SU LOCALIZACION EN MICRODOMINIOS DE LAS MEMBRANAS PLASMATICAS DE SINCICIOTROFOBLASTO Y SUS POSIBLES IMPLICANCIAS FUNCIONALES FONDECYT (1070695) Proyecto 2007-2011 Personal técnico y/o de apoyo
PREECLAMPSIA Y TRANSPORTE DE NUTRIENTES EN LA UNIDAD FETO PLACENTARIA=> EVIDENCIAS FUNCIONALES Y MOLECULARES DE UN CANAL DE CLORURO COMO UNA VIA DE PASO PARA TAURINA EN LA CARA MATERNA DEL SINCICIOTROFOBLASTO. FONDECYT (1040546) Proyecto 2004-2007 Personal técnico y/o de apoyo
Transplante funcional de canales iónicos de membranas de trofoblasto placentario humano en ovocitos de Xenopus laevis=> estudio de sus propiedades y regulación FONDECYT (1000647) Proyecto 2000-2003 Tesista


Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression Valderrama, MV Review ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2018)