PDI - Resultado de Búsqueda

Félix A. Rey

Director

Centre National de Recherche Scientifique (CNRS)

París, Francia

Structural biology focusing on mechanistic studies on pathogenic viruses, including entry steps and the interaction with the immune system. Among them the viral envelope proteins, their receptor interation and membrane fusion process..

Física teórica, Instituto Balseiro, Bariloche. Argentina, 1981
Virología Estructural, Universté de París XI, Orsay. Francia, 1998

Profesor Full Time

Pasteur Institute

Francia

2005 - A la fecha

Postdoctorado Full Time

Harvard University

Francia

1988 - 1995
Group Leader Full Time

Centre National de Recherche Scientifique (CNRS)

Chile

1995 - 1999
Director Full Time

Centre National de Recherche Scientifique (CNRS)

Chile

1999 - 2004
Director Full Time

Pasteur Institute

Chile

2004 - 2012
Director Full Time

Centre National de Recherche Scientifique (CNRS), Pasteur Institute

Chile

2007 - A la fecha

Médaille d’argent

CNRS

Francia

Award 2004
EMBO membership

EMBO

Chile

Membresía otorgado en 2005
Beijerinck Virology Prize

Royal Dutch Academy of Arts and Sciences

Chile

Premio en ciencia 2013


A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis Dubrau, Danilo; Tortorici, M. Alejandra; Rey, Félix A.; Tautz, Norbert; Cherry, Sara Article PLOS PATHOGENS (2017)
Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy Walls, Alexandra; Tortorici, M. Alejandra; Bosch, Berend-Jan; Frenz, Brandon; Rottier, Peter J. M.; DiMaio, Frank; Veesler, David Article Protein Science (2017)
The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein Fédry J, Liu Y, Péhau-Arnaudet G, Pei J, Li W, Tortorici MA, Traincard F, Meola A, Bricogne G, Grishin NV, Snell WJ, Rey FA, Krey T Article (2017)
The Envelope Proteins of the Bunyavirales. Guardado-Calvo P, Rey FA. Article (2017)
Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus Keck, Zhen-yong; Girard-Blanc, Christine; Wang, Wenyan; Lau, Patrick; Zuiani, Adam; Krey, Thomas; Diamond, Michael S.; Foung, Steven K. H.; Ou, J.-H. J. Article JOURNAL OF VIROLOGY (2016)
Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer Tortorici, M. Alejandra; Bosch, Berend-Jan; Frenz, Brandon; Rottier, Peter J. M.; DiMaio, Frank; Rey, Félix A.; Veesler, David Article NATURE (2016)
Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV Hastie, Kathryn M; Igonet, Sébastien; Sullivan, Brian M; Legrand, Pierre; Zandonatti, Michelle A; Robinson, James E; Garry, Robert F; Oldstone, Michael B; Saphire, Erica Ollmann Article Nature Structural & Molecular Biology (2016)
Dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus Dejnirattisai, Wanwisa; Supasa, Piyada; Wongwiwat, Wiyada; Rouvinski, Alexander; Barba-Spaeth, Giovanna; Duangchinda, Thaneeya; Sakuntabhai, Anavaj; Cao-Lormeau, Van-Mai; Malasit, Prida; Mongkolsapaya, Juthathip Article NATURE IMMUNOLOGY (2016)
Erratum: Structural basis of potent Zika–dengue virus antibody cross-neutralization Barba-Spaeth, Giovanna; Dejnirattisai, Wanwisa; Rouvinski, Alexander; Vaney, Marie-Christine; Medits, Iris; Sharma, Arvind; Sakuntabhai, Anavaj; Cao-Lormeau, Van-Mai; Haouz, Ahmed; England, Patrick; et al. Article NATURE (2016)
Functional Characterization of Glycoprotein H Chimeras Composed of Conserved Domains of the Pseudorabies Virus and Herpes Simplex Virus 1 Homologs Böhm, Sebastian W.; Backovic, Marija; Klupp, Barbara G.; Mettenleiter, Thomas C.; Fuchs, Walter; Longnecker, R. M. Article JOURNAL OF VIROLOGY (2016)
Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy Walls, Alexandra C; Frenz, Brandon; Snijder, Joost; Li, Wentao; DiMaio, Frank; Bosch, Berend-Jan; Veesler, David Article Nature Structural & Molecular Biology (2016)
Human Adaptation of Ebola Virus during the West African Outbreak Urbanowicz, Richard A.; McClure, C. Patrick; Sakuntabhai, Anavaj; Sall, Amadou A.; Kobinger, Gary; Müller, Marcel A.; Holmes, Edward C.; Rey, Félix A.; Simon-Loriere, Etienne; Ball, Jonathan K. Article Cell (2016)
Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc Guardado-Calvo, Pablo; Stettner, Eva; Jeffers, Scott Allen; Pérez-Vargas, Jimena; Tortorici, M. Alejandra; Jestin, Jean-Luc; England, Patrick; Rey, Félix A.; Kuhn, Richard J. Article ISI SCOPUS PLOS PATHOGENS (2016)
Prevalence of Equine Hepacivirus Infections in France and Evidence for Two Viral Subtypes Circulating Worldwide Pronost, S.; Hue, E.; Fortier, C.; Foursin, M.; Fortier, G.; Desbrosse, F.; Rey, F. A.; Pitel, P.-H.; Richard E.; Saunier, B. Article Transboundary and Emerging Diseases (2016)
Structural basis of potent Zika–dengue virus antibody cross-neutralization Barba-Spaeth, Giovanna; Dejnirattisai, Wanwisa; Rouvinski, Alexander; Vaney, Marie-Christine; Medits, Iris; Sharma, Arvind; Sakuntabhai, Anavaj; Cao-Lormeau, Van-Mai; Haouz, Ahmed; England, Patrick; et al. Article NATURE (2016)
A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus Ouizougun-Oubari, Mohamed; Pereira, Nelson; Tarus, Bogdan; Galloux, Marie; Lassoued, Safa; Fix, Jenna; Tortorici, M. Alejandra; Hoos, Sylviane; Baron, Bruno; England, Patrick; et al. Article JOURNAL OF VIROLOGY (2015)
A replication defect of pseudorabies virus induced by targeted α-helix distortion in the syntaxin-like bundle of glycoprotein H (V275P) is corrected by an adjacent compensatory mutation (V271A) Fuchs, Walter; Klupp, Barbara G.; Mettenleiter, Thomas C.; Backovic, Marija; Böhm, Sebastian W. Article journal of general virology (2015)
Corrigendum: A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus Dejnirattisai, Wanwisa; Wongwiwat, Wiyada; Supasa, Sunpetchuda; Zhang, Xiaokang; Dai, Xinghong; Rouvinsky, Alexander; Jumnainsong, Amonrat; Edwards, Carolyn; Quyen, Nguyen Than Ha; Duangchinda, Thaneeya; et al. Article NATURE IMMUNOLOGY (2015)
Determinants Involved in Hepatitis C Virus and GB Virus B Primate Host Restriction Marnata, Caroline; Saulnier, Aure; Mompelat, Dimitri; Krey, Thomas; Cohen, Lisette; Boukadida, Célia; Warter, Lucile; Fresquet, Judith; Vasiliauskaite, Ieva; Escriou, Nicolas; et al. Article JOURNAL OF VIROLOGY (2015)
Recognition determinants of broadly neutralizing human antibodies against dengue viruses Rouvinski, Alexander; Guardado-Calvo, Pablo; Barba-Spaeth, Giovanna; Duquerroy, Stéphane; Vaney, Marie-Christine; Kikuti, Carlos M.; Navarro Sanchez, M. Erika; Dejnirattisai, Wanwisa; Wongwiwat, Wiyada; Haouz, Ahmed; et al. Article NATURE (2015)
X-Ray Structure of the Pestivirus NS3 Helicase and Its Conformation in Solution Tortorici, M. Alejandra; Duquerroy, Stéphane; Kwok, Jane; Vonrhein, Clemens; Lamp, Benjamin; Rümenapf, Till; Vachette, Patrice; Rey, Félix A.; Diamond, M. S. Article JOURNAL OF VIROLOGY (2015)
A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus Dejnirattisai, Wanwisa; Wongwiwat, Wiyada; Supasa, Sunpetchuda; Zhang, Xiaokang; Dai, Xinghong; Rouvinsky, Alexander; Jumnainsong, Amonrat; Edwards, Carolyn; Quyen, Nguyen Than Ha; Duangchinda, Thaneeya; et al. Article NATURE IMMUNOLOGY (2014)
Rubella Virus: First Calcium-Requiring Viral Fusion Protein Dubé, Mathieu; Kielian, Margaret; Sherry, Barbara Article PLOS PATHOGENS (2014)

Félix Rey

Director

Centre National de Recherche Scientifique (CNRS)

París, Francia

Félix A. Rey

Líneas de Investigación

Educación

Física teórica, Instituto Balseiro, Bariloche. Argentina, 1981

Virología Estructural, Universté de París XI, Orsay. Francia, 1998

Experiencia Académica

Profesor Full Time

Experiencia Profesional

Postdoctorado Full Time

Group Leader Full Time

Director Full Time

Director Full Time

Director Full Time

Premios y Distinciones

Médaille d’argent

EMBO membership

Beijerinck Virology Prize

Article (23)