Man

Jenaro Garcia-Huidobro Prieto

Profesor Asistente

Universidad de Talca

Talca, Chile

Líneas de Investigación


Polyamines, genetic variability, personalized medicine and cancer

Educación

  •  Bioquímica, Universiad de Concepcion. Chile, 2006
  •  Bioquímico, UNIVERSIDAD DE CONCEPCION. Chile, 2008
  •  Bioquímica, UNIVERSIDAD DE CONCEPCION. Chile, 2008
  •  Biochemistry and Molecular and Cellular Biology, University of Arizona. Estados Unidos, 2014

Experiencia Académica

  •   Post-Doctoral Research Associate Full Time

    UNIVERSITY OF ARIZONA

    Arizona Cancer Center

    Tucson, Estados Unidos

    2014 - 2014

  •   Post-Doctoral Fellow Full Time

    UNIV TEXAS M.D. ANDERSON CANCER CENTER

    Translational Molecular Pathology

    Houston, Estados Unidos

    2014 - 2015

  •   Post-Doctoral Research Associate Full Time

    UNIVERSITY OF MIAMI

    Sylvester Comprehensive Cancer Center

    Miami, Estados Unidos

    2015 - 2018

  •   Research Associate Full Time

    UNIVERSITY OF MIAMI

    Sylvester Comprehensive Cancer Center

    Miami, Estados Unidos

    2018 - 2019


 

Article (6)

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

Beckedorff, F; Zhang, YS; Colaprico, A; Bilbao, D; Figueroa, ME; LaCava, J; Morey, L

Article ISI SCOPUS
NATURE COMMUNICATIONS  (2018)

Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome

Filgueira, C. S.; Nicolov, E.; Hood, R. L.; Lin, J. Z.; Fraga, D.; Webb, P.; Sabek, O. M.; Gaber, A. O.; Phillips, K. J.; Grattoni, A.

Article ISI
INTERNATIONAL JOURNAL OF OBESITY  (2016)

The Protease Degrading Sperm Histones Post-Fertilization in Sea Urchin Eggs Is a Nuclear Cathepsin L That Is Further Required for Embryo Development

Morin, V; Sanchez-Rubio A.; Aze A.; Iribarren C.; Fayet C.; Desdevises Y.; Garcia-Huidobro, J; Imschenetzky M.; Puchi, M

Article ISI SCOPUS
PloS one  (2012)

POLYAMINES IN CANCER

Paz, Edwin A.; Garcia-Huidobro, Jenaro; Ignatenko, Natalia A.; Makowski, GS

Article ISI
ADVANCES IN CLINICAL CHEMISTRY, VOL 54  (2011)

A New Nuclear Protease With Cathepsin L Properties Is Present in HeLa and Caco-2 Cells

Puchi, M; Garcia-Huidobro, J; Cordova, C; Aguilar, R.; Dufey E.; Imschenetzky M.; Bustos P.; Morin, V

Article ISI SCOPUS
Journal of Cellular Biochemistry  (2010)

Cathepsin L inhibitor I blocks mitotic chromosomes decondensation during cleavage cell cycles of sea urchin embryos

Morin, V; Sanchez A.; Quinones, K; Huidobro, JG; Iribarren C.; Bustos P.; Puchi, M; Geneviere, AM; Imschenetzky M.

Article ISI SCOPUS
JOURNAL OF CELLULAR PHYSIOLOGY  (2008)

Patent (2)

Carcinoma diagnosis and treatment based on ODC1 genotype



Patent
 (2020)

Predictive markers for polyamine inhibitor cancer therapies



Patent
 (2018)

Proyecto (9)

ENHANCER RNA THERAPY

National Institutes of Health (NIH) (1DP1CA228041-01)

Proyecto
2017-2022
Postdoctorado

A TUNABLE DELIVERY PLATFORM FOR IN VIVO INVESTIGATION OF THERAPEUTICS

National Institutes of Health (NIH) (1R21GM111544-01)

Proyecto
2014-2017
Postdoctorado

NON-CODING RNAS IN TRANSCRIPTION AND CHROMATIN ARCHITECTURE

National Institutes of Health (NIH) (5R01GM105754-05)

Proyecto
2014-2019
Postdoctorado

GENETIC VARIABILITY AS PROGNOSTIC OR PREDICTIVE FACTORS IN COLORECTAL EPITHELIAL TISSUE IN RISK OF COLORECTAL CANCER

National Institutes of Health (NIH) (3P50CA095060-10S2)

Proyecto
2011-2015
Tesista

PLEIOTROPIC FUNCTIONS OF FOXC2 IN EMT, STEM CELLS AND BREAST CANCER PROGRESSION

National Institutes of Health (NIH) (1R01CA155243-01)

Proyecto
2011-2016
Postdoctorado

ELUCIDATION OF INTEGRATOR'S FUNCTION

National Institutes of Health (NIH) (5R01GM078455-08)

Proyecto
2010-2018
Postdoctorado

PREVENTION OF APC-DEPENDENT INTESTINAL CARCINOGENESIS

National Institutes of Health (NIH) (5R01CA123065-05)

Proyecto
2010-2014
Tesista

ROL DE LA ESTRUCTURA DE LA CROMATINA DURANTE LA INICIACIÓN DE LA REPLICACIÓN POSTFECUNDACIÓN EN ERIZOS DE MAR

FONDECYT (C07B05)

Proyecto
2007-2010
Tesista

CISTEIN-PROTEASA QUE PARTICIPA EN REMODELACION DEL PRONUCLEO MASCULINO POSTFECUNDACION=> CONSOLIDACION DE UN MODELO Y PERSPECTIVAS FUTURAS.

FONDEF (1050100)

Proyecto
2005-2008
Tesista

3
Violeta Morin

Associate Research

Bioquímica y Biología Molecular

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

2
Andrea Sanchez

Profesor Asociado

Bioquímica Clínica e Inmunología

UNIVERSIDAD DE CONCEPCION

concepcion, Chile

1
Rodrigo Aguilar

Assistant Professor

Institute for Biomedical Sciences

Universidad Andrés Bello

Santiago, Chile

8
Jenaro Garcia-Huidobro

Profesor Asistente

Universidad de Talca

Talca, Chile