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David Adrián Sáez San Martín

Investigador Postdoctoral

Universidad de Concepción

Concepción, Chile

Líneas de Investigación


Molecular Dynamics, Enzymatic Catalysis, Enzymatic Design

Educación

  •  Química, UNIVERSIDAD DE CONCEPCION. Chile, 2017
  •  Química y Farmacia, UNIVERSIDAD DE CONCEPCION. Chile, 2012

Experiencia Académica

  •   Colaborador Docente Part Time

    UNIVERSIDAD DE CONCEPCION

    Farmacia

    Concepcion, Chile

    2018 - A la fecha


 

Article (7)

Atom-Condensed Fukui Function in Condensed Phases and Biological Systems and Its Application to Enzymatic Fixation of Carbon Dioxide

Oller J.; Saez D.A.; Vöhringer-Martinez E.

Article ISI SCOPUS
JOURNAL OF PHYSICAL CHEMISTRY A  (2020)

Awakening the Sleeping Carboxylase Function of Enzymes: Engineering the Natural CO2-Binding Potential of Reductases

Bernhardsgrütter I.; Schell K.; Peter D.M.; Borjian F.; Saez D.A.; Vöhringer-Martinez E.; Erb T.J.

Article ISI SCOPUS
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  (2019)

Electronic structure benchmark calculations of inorganic and biochemical carboxylation reactions

Douglas-Gallardo, OA; Saez, DA; Vogt-Geisse, S; Vohringer-Martinez, E

Article ISI SCOPUS
JOURNAL OF COMPUTATIONAL CHEMISTRY  (2019)

Four amino acids define the CO2 binding pocket of enoyl-CoA carboxylases/reductases

Stoffel G.M.M.; Saez D.A.; DeMirci H.; Vögeli B.; Rao Y.; Zarzycki J.; Yoshikuni Y.; Wakatsuki S.; Vöhringer-Martinez E.; Erb T.J.

Article ISI SCOPUS
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  (2019)

Catalytic Reaction Mechanism in Native and Mutant Catechol-O-methyltransferase from the Adaptive String Method and Mean Reaction Force Analysis

Saez, DA; Zinovjev, K; Tunon, I; Voringer-Martinez, E

Article ISI SCOPUS
JOURNAL OF PHYSICAL CHEMISTRY B  (2018)

The effect of the environment on the methyl transfer reaction mechanism between trimethylsulfonium and phenolate

Saez, David Adrian; Vogt-Geisse, Stefan; Inostroza-Rivera, Ricardo; Kuba?, Tomáš; Elstner, Marcus; Toro-Labbé, Alejandro; Vöhringer-Martinez, Esteban

Article ISI SCOPUS
PHYSICAL CHEMISTRY CHEMICAL PHYSICS  (2016)

A consistent S-Adenosylmethionine force field improved by dynamic Hirshfeld-I atomic charges for biomolecular simulation

Saez, DA; Vohringer-Martinez, E

Article ISI SCOPUS
Journal of Computer-Aided Molecular Design  (2015)

Proyecto (6)

NADPH, 1,4-Dihydropyridines and Unsaturated Compounds: Exploring the Main Reducing Strategy of Nature.

David Adrian Saez; Stefan Vogt-Geisse

Proyecto
 (2019)

REDCO2:Rational Enzyme Design for CO2 fixation

Esteban Vöhringer-Martinez; Stefan Vogt-Geisse; David Adrian Saez; Rodrigo Recabarren

Proyecto
 (2019)

Max Planck Partner Group=> A mechanistic model for CO2 fixation of Ccr enzymes from QM/MM simulations and mutational studies.

Max Planck Society (0)

Proyecto
2017-2019
Postdoctorado

Núcleo Milenio Procesos Químicos y Catálisis

Iniciativa Científica Milenio (110082)

Proyecto
2015-2016
Personal técnico y/o de apoyo

ON THE TRACK OF ENZYMES' FUNCTION=> NEW INSIGHTS FROM THE MEAN REACTION FORCE

FONDECYT (11121179)

Proyecto
2012-2015
Tesista

ON THE TRACK OF ENZYMES' FUNCTION=> NEW INSIGHTS FROM THE MEAN REACTION FORCE

FONDECYT (11121179)

Proyecto
2012-2015
Personal técnico y/o de apoyo

9
David Sáez

Investigador Postdoctoral

Universidad de Concepción

Concepción, Chile

7
Esteban Vohringer-Martinez

Profesor Asociado

Físico-Química

FACULTAD DE CIENCIAS QUÍMICAS

Concepción, Chile

1
Javier Oller

Investigador Postdoctoral

Universidad de Chile

Santiago de Chile, Chile

1
Alejandro Toro

PROFESOR TITULAR

Química Física

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile