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Francesco Mattia Mancuso

Bioinformatician

Vall d'Hebron Insitute of Oncology (VHIO)

Bacelona, España

Translational research to both accelerate and advance personalized and targeted therapies against cancer.

Bioinformatics, University of Milano - Bicocca . Italia, 2006
Molecular biotechnoogy, University of Milano - Bicocca . Italia, 2003

Bioinformatician Full Time

Vall d'Hebron Insitute of Oncology (VHIO)

Barcelona, España

2014 - A la fecha
Bioinformatician Full Time

Centre de Regulació Genomica (CRG)

Barcelona, España

2010 - 2014
Bioinformatician Full Time

I.E.O. (European Institute of Oncology)

Milano, Italia

2008 - 2010
Bioinformatician Full Time

Cogentech

Milano, Italia

2008 - 2010
Bioinformatic technician Full Time

PRIMM srl

Milano, Italia

2006 - 2007
Bioinformatics Master student Full Time

IFOM

Milano, Italia

2004 - 2005


Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors Article ISI BMC CANCER (2020)
Epigenetic EGFR Gene Repression Confers Sensitivity to Therapeutic BRAFV600E Blockade in Colon Neuroendocrine Carcinomas Arques, Oriol; Hernandez Mora, Jose Ramon; Barriuso, Jorge; Lopez Lopez, Carlos; Garcia-Carbonero, Rocio; Paolo, Nuciforo; Esteller, Manel; Martinez-Cardus, Anna Article ISI CLINICAL CANCER RESEARCH (2020)
Identification of Expression Profiles Defining Distinct Prognostic Subsets of Radioactive-Iodine Refractory Differentiated Thyroid Cancer from the DECISION Trial Matos, Ignacio; Iglesias, Carmela; Zafon, Carles; Palmer, Hector G.; Muinos, Laura; Hernando, Jorge; Villacampa, Guillermo; Pena, Carol E.; Brose, Marcia S.; Schlumberger, Martin Article ISI MOLECULAR CANCER THERAPEUTICS (2020)
Impact of circulating tumor DNA mutant allele fraction on prognosis in RAS-mutant metastatic colorectal cancer Chianese, Chiara; Sanz-Garcia, Enrique; Martinelli, Erica; Noguerido, Alba; Mattia Mancuso, Francesco; Grasselli, Julieta; Cardone, Claudia; Abate, Riziero Esposito; Martini, Giulia; Santos, Cristina; et al. Article ISI MOLECULAR ONCOLOGY (2019)
Activity of HSP90 Inhibiton in a Metastatic Lung Cancer Patient With a Germline BRCA1 Mutation Cedres, Susana; Cruz, Cristina; Martinez de Castro, Ana; Pardo, Nuria; Martinez-Marti, Alex; Remon, Jordin; Zeron-Medina, Jorge; Llop-Guevara, Alba; Miquel, Josep M.; Sansano, Irene; et al. Article ISI JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
Early evolutionary divergence between papillary and anaplastic thyroid cancers Mancuso, F. M.; Zafon, C.; Cameselle-Teijeiro, J. M.; Recio, J. A.; Seoane, J. Article ISI ANNALS OF ONCOLOGY (2018)
Genetic Profiles of Squamous Cell Carcinomas Associated with Recessive Dystrophic Epidermolysis Bullosa Unveil NOTCH and TP53 Mutations and an Increased MYC Expression Sans-DeSanNicolas, Lidia; Caratu, Ginevra; Vidal-Cortes, Oriol; Sanchez-Redondo, Sara; Ferrer, Berta; Gonzalez-Sanchez, Elena; Perez-Alea, Mileidys; McGrail, Kimberly; Hernandez-Losa, Javier; Bodet, Domingo; et al. Article ISI JOURNAL OF INVESTIGATIVE DERMATOLOGY (2018)
Multigene panel testing beyond BRCA1/2 in breast/ovarian cancer Spanish families and clinical actionability of findings Bonache, Sandra; Esteban, Irene; Moles-Fernandez, Alejandro; Tenes, Anna; Duran-Lozano, Laura; Montalban, Gemma; Bach, Vanessa; Carrasco, Estela; Gadea, Neus; Lopez-Fernandez, Adria; et al. Article ISI JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2018)
RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer Castroviejo-Bermejo, M.; Llop-Guevara, A.; Ibrahim, Y. H.; Gris-Oliver, A.; Bonache, S.; Morancho, B.; Bruna A.; Rueda, O. M.; Lai Z.; Polanska, U. M.; et al. Article ISI ANNALS OF ONCOLOGY (2018)
Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells Imperlini, Esther; Gnecchi, Massimiliano; Rognoni, Paola; Ciuffreda, Maria Chiara; Palladini, Giovanni; Bozzola, Margherita; Malpasso, Giuseppe; Valentini, Veronica; Palladini, Giuseppina; Orru, Stefania; et al. Article ISI SCIENTIFIC REPORTS (2017)
Rescuing discarded spectra: Full comprehensive analysis of a minimal proteome Lluch-Senar, Maria; Climente-Gonzalez, Hector; Pena-Paz, Marcia I. Article ISI PROTEOMICS (2016)
Signatures of Evolutionary Adaptation in Quantitative Trait Loci Influencing Trace Element Homeostasis in Liver Engelken, Johannes; Bonet, Nuria; Scherr, Anna-Lena; Jimenez-Alvarez, Victoria; Codina-Sola, Marta; Medina-Stacey, Daniel; Spataro, Nino; Stoneking, Mark; Calafell, Francesc; Bosch, Elena Article ISI MOLECULAR BIOLOGY AND EVOLUTION (2016)
miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth Bremang, Michael; Spadotto, Valeria; Musiani, Daniele; Vitale, Elena; Varano, Gabriele; Cairns, David A.; Casola, Stefano Article ISI NATURE COMMUNICATIONS (2015)
Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage Isus, Laura; Herrando-Grabulosa, Mireia; Sabido, Eduardo; Fores, Joaquim; Aloy, Patrick Article ISI SCIENTIFIC REPORTS (2015)
The propagation of perturbations in rewired bacterial gene networks Baumstark, Rebecca; Haenzelmann, Sonja; Tsuru, Saburo; Schaerli, Yolanda; Francesconi, Mirko; Castelo, Robert; Isalan, Mark Article ISI NATURE COMMUNICATIONS (2015)
The seipin complex Fld1/Ldb16 stabilizes ER-lipid droplet contact sites Buxo, Laura; Mora, Gabriel; Funaya, Charlotta; Idrissi, Fatima-Zahra; Gomez, Raul; Muntanya, Julia; Carvalho, Pedro Article ISI JOURNAL OF CELL BIOLOGY (2015)
Bioinformatic Approaches to Increase Proteome Coverage Cappadona, Salvatore; Simo, C; GarciaCanas, V Article ISI FUNDAMENTALS OF ADVANCED OMICS TECHNOLOGIES: FROM GENES TO METABOLITES (2014)
Lifelong Exercise Training Modulates Cardiac Mitochondrial Phosphoproteome in Rats Ferreira, Rita; Vitorino, Rui; Padrao, Ana Isabel; Moreira-Goncalves, Daniel; Castro-Sousa, Goncalo; Henriques-Coelho, Tiago; Oliveira, Paula A.; Barros, Antonio S.; Duarte, Jose Alberto; Amado, Francisco Article ISI JOURNAL OF PROTEOME RESEARCH (2014)
Profiling the Secretome and Extracellular Proteome of the Potato Late Blight Pathogen Phytophthora infestans Meijer, Harold J. G.; Seidl, Michael F.; Govers, Francine Article ISI MOLECULAR & CELLULAR PROTEOMICS (2014)
Integrative quantitation enables a comprehensive proteome comparison of two Mycoplasma pneumoniae genetic perturbations Borras, Eva; Espadas, Guadalupe; Maier, Tobias; Chiva, Cristina; Sabido, Eduard Article ISI MOLECULAR BIOSYSTEMS (2013)
Data extraction from proteomics raw data: An evaluation of nine tandem MS tools using a large Orbitrap data set Bunkenborg, Jakob; Wierer, Michael; Molina, Henrik Article ISI JOURNAL OF PROTEOMICS (2012)
Widespread generation of alternative UTRs contributes to sex-specific RNA binding by UNR Mihailovich, Marija; Wurth, Laurence; Zambelli, Federico; Abaza, Irina; Militti, Cristina; Roma, Guglielmo; Pavesi, Giulio; Gebauer, Fatima Article ISI RNA (2012)
Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output Celona, Barbara; Weiner, Assaf; Di Felice, Francesca; Cesarini, Elisa; Rossi, Riccardo L.; Gregory, Lorna; Baban, Dilair; Rossetti, Grazisa; Grianti, Paolo; Pagani, Massimiliano; et al. Article ISI PLOS BIOLOGY (2011)
Identification and Analysis of Co-Occurrence Networks with NetCutter Article ISI PLOS ONE (2008)
Graph-based identification of cancer signaling pathways from published gene expression signatures using PubLiME Cittaro, Davide Article ISI NUCLEIC ACIDS RESEARCH (2007)
Lap2 alpha expression is controlled by E2F and deregulated in various human tumors Parise, Paola; Masciadri, Barabara; Quarto, Micaela; Francois, Stefanie Article ISI CELL CYCLE (2006)
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical role in cell-cycle control Finocchiaro G. Article ISI BMC BIOINFORMATICS (2005)
Evolving Landscape of Molecular Prescreening Strategies for Oncology Early Clinical Trials Article
HumMeth27QCReport: an R package for quality control and primary analysis of Illumina Infinium methylation data Article BMC RESEARCH NOTES

Francesco Mancuso

Bioinformatician

Cancer Genomics

Vall d'Hebron Insitute of Oncology (VHIO)

Bacelona, España

Francesco Mattia Mancuso

Líneas de Investigación

Educación

Bioinformatics, University of Milano - Bicocca . Italia, 2006

Molecular biotechnoogy, University of Milano - Bicocca . Italia, 2003

Experiencia Profesional

Bioinformatician Full Time

Bioinformatician Full Time

Bioinformatician Full Time

Bioinformatician Full Time

Bioinformatic technician Full Time

Bioinformatics Master student Full Time

Article (29)