Man

Jaime G. Melendez Rojel

Prof. Asistente

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Mecanismos moleculares que explican el desarrollo de cáncer colónico ypancreático. Aspectos asociados al uso de nanopartículas como vectores de drug delivery en el control del cáncer.

Educación

  •  Cs Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1994
  •  Bioquímica, UNIVERSIDAD DE CHILE. Chile, 2001
  •  Biomedicine, Cincinnati Children´s Hospital Medical Center. Estados Unidos, 2010

Experiencia Profesional

  •   Prof. Asistente Full Time

    P. Universidad Católica de Chile

    Santiago, Chile

    2011 - 2019


 

Article (4)

Cdc42 Coordinates Proliferation, Polarity, Migration, and Differentiation of Small Intestinal Epithelial Cells in Mice

Meléndez, J; Liu, M; Sampson, L; Akunuru, S; Han, XN; Vallance, J; Witte, D; Shroyer, N; Zheng, Y

Article ISI SCOPUS
Gastroenterology  (2013)

Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation

Katayama, KI; Meléndez, J; Baumann, JM; Leslie, JR; Chauhan, BK; Nemkul, N; Lang, RA; Kuan, CY; Zheng, Y; Yoshida, Y

Article ISI
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  (2011)

RhoA GTPase Is Dispensable for Actomyosin Regulation but Is Essential for Mitosis in Primary Mouse Embryonic Fibroblasts

Meléndez, J; Stengel, K; Zhou, X; Chauhan, BK; Debidda, M; Andreassen, P; Lang, RA; Zheng, Y

Article ISI
JOURNAL OF BIOLOGICAL CHEMISTRY  (2011)

Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes

Foncea, R; Gálvez, A; Pérez, V; MORALES, MP.; Calixto, A; Meléndez, J; Gonzalez-Jara, F; Díaz-Araya, G; Sapag-Hagar, M; Sugden, PH; et al.

Article ISI
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS  (2000)

Abstract (1)

RhoA Is An Essential Regulator of Mitosis and Survival During Hematopoietic Stem Cell Differentiation to Multipotent Progenitors

Znou, X; Meléndez, J; Feng, YX; Lang, R; Zheng, Y

Abstract
BLOOD  (2011)

Review (1)

Signaling Role of Cdc42 in Regulating Mammalian Physiology

Meléndez, J; Grogg, M; Zheng, Y

Review ISI
JOURNAL OF BIOLOGICAL CHEMISTRY  (2011)

1
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

6
Jaime Melendez

Prof. Asistente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Anita Gálvez

Profesor Asistente

Biomédico

Universidad de Antofagasta

Antofagasta, Chile