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Mirta Isabel Acuña Ávila

Lider del Programa de Uso racional de Antimicrobianos

HOSPITAL ROBERTO DEL RÍO

Santiago, Chile

Infecciones respiratorias virales; bacterianas; Biologa molecular en el diagnstico de infecciones; Interccn Bacteria-Hospedero; Diagnstico molecular; Neutropenia Febril / infecciones Fngicas Invasoras; Reactantes de fase aguda; Infecciones intrahospitalarias; Consumo de antibiticos

Medica Cirujana, UNIVERSIDAD DE CONCEPCION. Chile, 1994
Especialista en Pediatría, UNIVERSIDAD DE CHILE. Chile, 2000
Especialista en Infectología pediátrica, UNIVERSIDAD DE CHILE. Chile, 2007
salud publica, UNIVERSIDAD DE CHILE. Chile, 2023

Profesora asociada Part Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2000 - At present

Lider Programa de Uso Racional de Antimicrobianos Full Time

Hospital Roberto del Río

Santiago, Chile

2000 - At present
Directora del Hospital Other

Hospital Roberto del Río

Santiago, Chile

2018 - 2019
subdirectora del hospital Full Time

Hospital Roberto del Río

Santiago, Chile

2017 - 2018

Mejor egresada de pediatría

UNIVERSIDAD DE CHILE

Chile, 2000

Distinción otorgada por obtener las mejores calificaciones durante la especialización en pediatría


FilmArray® Meningoencephalitis panel in the diagnosis of central nervous system infections: stewardship and cost analysis in a paediatric hospital in Chile Acuna, Mirta; Benadof, Dona; Yohannessen, Karla; Leiva, Yennybeth; Clement, Pascal Article ISI BMC PEDIATRICS (2022)
Recomendaciones para diagnóstico y tratamiento de la infección del tracto urinario en pediatría. Parte 1 Valentina Gutiérrez1,2,3,a, Regina Pérez1,3,a, Daniela Pavez1,4,5,a, Pilar Hevia4,c, Mirta Acuña1,6,a, Dona Benadof1,6,7,b, Claudio González1,8,d, María Carolina Rivacoba9,10,a y José Cofré11,a Article SCIELO REVISTA CHILENA DE INFECTOLOGIA (2022)
Efficacy and safety of withholding antimicrobial treatment in children with cáncer, fever and neutropenia, with a demostrated viral respiratory infection=> a randomized clinical trial Santolaya ME, Alvarez AM; Acuña M, Avilés CL; Salgado C, Tordecilla J; Varas M, Venegas M; Villarroel M, Zubieta M; Toso A, Bataszew A; Farfán, de la Maza V; Vergara A, Valenzuela R Article Clinical Microbiology and Infection (2017)
Aspergillus fumigatus mediastinitis in an immunocompetent pediatric patient after heart surgery Acuña M.; Farfan, F; Cofré F.; Benadof, D Article ISI REVISTA CHILENA DE INFECTOLOGIA (2016)
Chilean consensus of prevention, diagnosis and treatment of Clostridium difficile-associated diarrhea Hernandez-Rocha, C; Pidal, P; Ajenjo, MC; Quera, R; Quintanilla, M; Lubascher, J; Jemenao, MI; Ibáñez P.; Alvarez-Lobos, M; Diomedi A.; Marcotti, A; Acuña M.; Arab, JP; Riquelme A.; candia, r; Carvajal S. Article ISI REVISTA CHILENA DE INFECTOLOGIA (2016)
Consenso chileno de prevención, diagnóstico y tratamiento de la diarrea asociada a Clostridium difficile Cristian Hernández-Rocha, Paola Pidal; M. Cristina Ajenjo, Rodrigo Quera; Marcela Quintanilla, Jaime Lubascher; M. Irene Jemenao, Patricio Ibáñez; Manuel Álvarez-Lobos, Alexis Diomedi; Alejandra Marcotti, Mirta Acuña; Juan P Arab, Arnoldo Riquelme Article Revista Chilena Infectología (2016)
Community associated-methicillin-resistant Staphylococcus aureus (SAMR-AC): comunication of the first four pediatric cases in the Roberto del Rio Children's Hospital Acuña M.; Benadof, D; Jadue C.; Hormazabal, JC.; Alarcón P.; Contreras, J.; Torres R.; Mulchi, C; Aguayo, C.; Fernandez, J; Araya, P Article ISI REVISTA CHILENA DE INFECTOLOGIA (2015)
Grupo colaborativo de Resistencia Bacteriana, Chile=> recomendaciones 2014 para el control de la resistencia bacteriana Cifuentes M, Silva F; Arancibia JM, Rosales R; Ajenjo MC, Riedel G; Camponovo R, Labarca J; Grupo Colaborativo de Resistencia Bacteriana; Chile.*Grupo Colaborativo de Resistencia Bacteriana Integrantes Taller 1=> Silva Francisco, Camponovo Rossana Article Revista Chilena de Infectología (2015)
Risk factor of intestinal colonization with vancomycin resistant Enterococcus spp in hospitalized pediatric patients with oncological disease Loyola P.; Tordecilla, J; Benadof, D; Yohannessen, K; Acuña M. Article ISI REVISTA CHILENA DE INFECTOLOGIA (2015)
Differential time to positivity and quantitative cultures for noninvasive diagnosis of catheter-related blood stream infection in children Acuña M.; O´Ryan, M; Cofre J.; Álvarez I.; Benadof, D; Rodríguez, P.; Torres, MT; Aguilera L.; Santoloya, ME Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2008)


Immunological Evaluation of Patients Admitted with Invasive Bacterial Infections to Hospital de Ninos Roberto del Rio in Santiago, Chile Acuña M.; Poli-Harlowe, C; Cofré F.; Benadof, D; Vega, AR; Riffo V.; Benavente F; Inostroza J. Abstract ISI JOURNAL OF CLINICAL IMMUNOLOGY (2015)
Therapeutic drug monitoring of voriconazole in children with cancer González C; Rojas, MJ; Villena R.; Parra, A.; Zubieta, M; Salgado, C.; Acuña M.; Benadof, D Abstract ISI PHARMACOTHERAPY (2015)


Escala de predicción de infecciones postcirugía cardíaca en pediatría Acuña M. BookReview SCIELO SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2012)


A Prospective Study to Assess the Pediatric Respiratory Syncytial Virus (RSV) Electronic Severity an Outcome Rating System (PRESORS) and Clinical Endpoints in Neonates, Infants, and Children >= 36 month of Age Hospitalized with RSV Infection Janssen Pharmaceutica NV (64041575RSV0001) Proyecto 2017-2019 Inv. Principal
Genetic and systemic biomarkers associated with severity of invasive fungal disease in children with cancer, fever and neutropenia=> A new insight FONDECYT (1161662) Proyecto 2016-2020 Coinvestigador(a)
CLINICAL SEVERITY AND SPECIFIC GENE EXPRESSION PROFILE IN RESPIRATORY VIRAL INFECTIONS IN CHILDREN WITH CANCER, FEVER AND NEUTROPENIA=> A STEP FORWARD. FONDECYT (1130911) Proyecto 2013-2016 Coinvestigador(a)
A PHASE II/III STUDY OF CHIMERIC MONOCLONAL ANTIBODIES TO SHIGA TOXINS 1 (caStx1) AND (caStx2) ADMINISTERED CONCOMITANTLY TO CHILDREN WITH SHIGA TOXIN-PRODUCING BACTERIAL (STPB) INFECTION AND BLOODY DIARRHEA Financiamiento Internacional (caStx1) Proyecto 2010-2012 Inv. Principal
A PHASE 2B/3, MULTI-CENTER, OBSERVED-BLIND CONTROLLED STUDY OF THE SAFETY, TOLERABILITY AND INMUNOGENICITY OF NOVARTIS MENINGOCOCCAL B RECOMBINANT VACCINE ADMINISTERED TO HAELTHY ADOLESCENTS AGED 11-17 YEARS ACCORDING TO DIFFERENT VACCINATION SCHEDULES Novartis Vaccines (V72P10) Proyecto 2008-2010 Coinvestigador(a)
SAFETY STUDY OF MENACTRA (MENINGOCOCCAL (GROUPS A, C , Y AND W-135) POLYSACCHARIDE DIPHTERIA TOXOID CONJUGATE VACCINE) WHEN ADMINISTERED WITH OTHER PEDIATRICS VACCINES TO HEALTHY TODDLERS Financiamiento Internacional (xxx) Proyecto 2008-2008 Coinvestigador(a)
A PHASE 2 OBSERVER-BLIND FOLLOW-UP STUDY WITH TWO GROUPS TO ASSES THE REACTOGENICITY AND INMUNOGENICITY OF GSK 10-VALENT PNEUMOCOCCAL CONJUGATE VACCINE (GSK 102485OA) WHEN EITHER GIVEN AS A BOOSTER DOSE IN PRIMED CHILDREN OR AS TWO-DOSE CATCH UP INMUNIZAT Financiamiento Internacional (GSK 1024850A) Proyecto 2007-2007 Coinvestigador(a)
A PHASE II RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE A SINGLE INTRAVENOUS DOSE OF MOTAVIZUMAB (MEDI-524), A HUMANIZED ENHANCED POTENCY MONOCLONAL ANTIBODY AGAINST RESPIRATORY SYNCYTIAL VIRUS (SRV), FOR THE TREATMENT OF CHILDREN HOSPIT Financiamiento Internacional (MEDI-524) Proyecto 2007-2008 Coinvestigador(a)
A PROSPECTIVE, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, COMPARATIVE STUDY TO EVALUATE THE SAFETY, LOCAL TOLERABILITY, AND CLINICAL OUTCOME OF ERTAPENEM SODIUM (MK-0826) vs. CEFTRIAXONE SODIUM IN PEDIATRIC PATIENTS WITH COMPLICATED URINARY TRACT INFECTION, Financiamiento Internacional (MK-0826-036) Proyecto 2002-2003 Coinvestigador(a)
AN OPEL-LABEL, INTRAVENOUS STUDY TO EVALUATE THE CEREBROSPINAL FLUID CONCENTRATION PROFILES OF MK-0826 IN PATIENTS AGED 3 MONTH THROUGH 17 AÑOS Financiamiento Internacional (MK0826-032) Proyecto 2001-2002 Coinvestigador(a)