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Miguel O'Ryan

Profesor Titular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Enteric Viruses;Rotavirus, Norovirus, Poliovirus; Vaccine development; Helicobacter pylori; acute endemic gastroenteritis; pathogen-host interactions; Infections in the immunocompromised host

Médico Pediatra , PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1987
Infectologo Pediatra, University of Texas Health Science Center at Houston. Estados Unidos, 1991

Presidente Part Time

Sociedad Chilena de Infectologia

Chile

1998 - 1999
Sub Director Part Time

Facultad de Medicina Universidad de Chile/Instituto de Ciencias Biomedicas

Chile

2003 - 2006
Director Part Time

Proyecto MECESUP UCH0608

Chile

2007 - 2009
Director Part Time

Programa de Microbiologia y Micologia, ICBM, Facultad de Medicina, Universidad de Chile

Chile

2007 - 2010
Integrante Part Time

Consejo de Evaluacion/Universidad de Chile

Chile

2009 - 2010
Vicerrector de Investigacion y Desarrollo Full Time

Universidad de Chile

Chile

2010 - 2012
Sub Director de Inovacion Part Time

Facultad de Medicina/Universidad de Chile

Chile

2012 - 2013
Miembro de Numero Other

Academia de medicina/Instituto de Chile

Chile

2012 - At present
Director de Investigacion y Tecnologia Part Time

Facultad de Medicina/Universidad de Chile

Chile

2013 - 2014
Director de relaciones Internacionales Part Time

Facultad de Medicina/Universidad de Chile

Chile

2015 - At present
Vice Presidente Part Time

Sociedad Chilena de Infectología

Chile

2000 - 2001
Investigador Asociado Part Time

Instituto Milenio de Inmunidad e Inmunoterapia

Chile

2017 - At present
Decano Full Time

Facultad de Medicina/Universidad de Chile

Santiago, Chile

2022 - At present

Dos tesis Doctorado y dos proyectos posdoctorado en últimos 10 años

Dra Yalda Lucero, 2009-2011 “Identificación de factores del hospedero y del agente relacionados con susceptibilidad y severidad en infección entérica por Norovirus en niños ?1 año de la Región Metropolitana” Tesis Doctoral Programa Doctorado en Ciencias Médicas, Facultad de Medicina, Universidad de Chile. Yalda Lucero.

Dra Beatriz Zavala, 2011-2013: Caracterización genética de los factores de virulencia de Helicobacter pylori asociados con la colonización persistente en niños menores de 3 años. Tesis Post Doctoral Conicyt.

Dr Felipe del Canto 2012-2015 3130555: Genomic and functional analysis to identify novel adhesins in enterotoxigenic Escherichia coli strains obtained from developing countries. Tesis Post Doctoral Conicyt.

Dra Andrea Orellana, 2012-2016: Modulación de la expresión de slc5a8, gen asociado a cáncer gastrointestinal, por la infección/colonización de helicobacter pylori en niños asintomáticos y sintomáticos. Tesis Doctoral Programa de Doctorado en Farmacología, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile.

Previo a este período Dirección de Tesis de Doctorado en Ciencias Médicas, Facultad de Medicina, Universidad de Chile
Dra. Yalda Lucero, Ph.D

Dirección de Tesis de Magister en Microbiología, Facultad de Medicina, Universidad de Chile
Dra Francisca Valdivieso, Mg
T.M. Ana María Salinas, Mg
Dr. Enrique Aguilera, Mg
Dr. Camilo Palma Suazo, Mg

Miguel O´Ryan Gallardo

Tokyo Medical and Dental University

Japón, 2015

Visiting Professor
Miguel O´Ryan Gallardo

Academia de Medicina del Instituto de Chile

Chile, 2012

Miembro de Número


Antimicrobial Resistance of <i>Helicobacter pylori</i> Isolated From Latin American Children and Adolescents (2008-2023): A Systematic Review Cabrera, Camila; Torres, Joaquin; Serrano, Carolina A.; Gallardo, Paulina; Orellana, Vicente; George, Sergio; O'Ryan, Miguel; Lucero, Yalda Article ISI HELICOBACTER (2024)
COVID-19 lateral flow IgG seropositivity and serum neutralising antibody responses after primary and booster vaccinations in Chile: a cross-sectional study Saure, Denis; O'Ryan, Miguel; Pablo Torres, Juan; Zuniga, Marcela; Soto-Rifo, Ricardo; Valiente-Echeverria, Fernando; Gaete-Argel, Aracelly; Neira, Ignasi; Saavedra, Vicente; Acevedo, Manica L.; Archila, Carmen; Acuna, Fernando; Rain, Manuel; Basso, Leonardo J. Article ISI LANCET MICROBE (2023)
Vibrio cholerae, classification, pathogenesis, immune response, and trends in vaccine development Montero, David A.; Vidal, Roberto M.; Velasco, Juliana; George, Sergio; Lucero, Yalda; Gomez, Leonardo A.; Carreno, Leandro J.; Garcia-Betancourt, Richard; O'Ryan, Miguel Article ISI FRONTIERS IN MEDICINE (2023)
Dynamic IgG seropositivity after rollout of CoronaVac and BNT162b2 COVID-19 vaccines in Chile: a sentinel surveillance study Saure, Denis; O'Ryan, Miguel; Torres, Juan Pablo; Zuniga, Marcela; Santelices, Emilio; Basso, Leonardo J. Article ISI LANCET INFECTIOUS DISEASES (2022)
<i>Helicobacter pylori,</i> clinical, laboratory, and noninvasive biomarkers suggestive of gastric damage in healthy school-aged children: A case-control study Lucero, Yalda; Lagomarcino, Anne J.; Torres, Juan P.; Roessler, Patricia; Mamani, Nora; George, Sergio; Huerta, Nicole; Gonzalez, Monica; O'Ryan, Miguel Article ISI INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)
Effect of <i>Helicobacter pylori</i> eradication therapy on clinical and laboratory biomarkers associated with gastric damage in healthy school-aged children: A randomized non-blinded trial Lucero, Yalda; Lagomarcino, Anne J.; Torres, Juan P.; Roessler, Patricia; Mamani, Nora; George, Sergio A.; Huerta, Nicole; Gonzalez, Monica; O'Ryan, Miguel G. Article ISI HELICOBACTER (2021)
Norovirus compared to other relevant etiologies of acute gastroenteritis among families from a semirural county in Chile Lucero, Yalda; Lagomarcino, Anne J.; Espinoza, Monica; Kawakami, Nanami; Mamani, Nora; Huerta, Nicole; Canto, Felipe Del; Farfan, Mauricio; Sawaguchi, Yoshihiro; George, Sergio; Ryan, Miguel O. ' Article ISI INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)
Antibody persistence and booster response in adolescents and young adults 4 and 7.5 years after immunization with 4CMenB vaccine Nolan, T; Santolaya, ME; de Looze, F; Marshall H.; Richmond, P; Henein, S; Rheault, P; Heaton, K; Perrett, KP; Garfield, H; Gupta, A; Ferguson, M; D'Agostino, D; Toneatto, D; O'Ryan, M Article ISI SCOPUS VACCINE (2019)
Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines Esposito S.; Stefanelli P.; Fry N.K.; Fedele G.; He, Q; Paterson P.; Tan T.; Knuf, M; Rodrigo C.; Olivier C.W.; Flanagan K.L.; Hung I.; Lutsar I.; Edwards K.; O'Ryan M.; Principi N. Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
Predominance of Rotavirus G8P[8] in a City in Chile, a Country Without Rotavirus Vaccination Lucero, Y; O'Ryan, M; Liparoti, G; Huerta, N.; Mamani, N; Ramani, S; Lagomarcino, AJ; Del Canto, F; Quense, J Article ISI SCOPUS JOURNAL OF PEDIATRICS (2019)
Coli Surface Antigen 26 Acts as an Adherence Determinant of Enterotoxigenic Escherichia coli and Is Cross-Recognized by Anti-CS20 Antibodies Cadiz, Leandro; Torres, Alexia; Valdes, Raul; Vera, Gabriel; Gutierrez, Daniela; Levine, Myron M.; Montero, David A.; O'Ryan, Miguel; Rasko, David A.; Stine, O. Colin; Vidal, Roberto; del Canto, Felipe Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2018)
Global epidemiology of serogroup B meningococcal disease and opportunities for prevention with novel recombinant protein vaccines Villena, Rodolfo; Safadi, Marco Aurelio P.; Valenzuela, Maria Teresa; Torres, Juan P.; Finn, Adam; O'Ryan, Miguel Article ISI SCOPUS HUMAN VACCINES & IMMUNOTHERAPEUTICS (2018)
Impact of Maternal Antibody on the Immunogenicity of Inactivated Polio Vaccine in Infants Immunized with Bivalent Oral Polio Vaccine: Implications for the Polio Eradication Endgame Gaensbauer J.T.; Gast C.; Bandyopadhyay A.S.; O'Ryan M.; Saez-Llorens X.; Rivera L.; Lopez-Medina E.; Melgar M.; Weldon W.C.; Oberste M.S.; RÃ¼ttimann R.; Clemens R.; Asturias E.J. Article ISI SCOPUS Clinical Infectious Diseases (2018)
Indications for Helicobacter Pylori Eradication Lucero, Yalda.; George, Sergio; O’Ryan, Miguel Article ISI JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2018)
Indications for Helicobacter Pylori Eradication: Do We Need To Consider To Screen and Treat Asymptomatic Children? Lucero, Yalda.; George, Sergio; O'Ryan, Miguel Article J Pediatr Gastroenterol Nutr. (2018)
Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine-only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chilean Infants Brickley E.B.; Wieland-Alter W.; Connor R.I.; Ackerman M.E.; Boesch A.W.; Arita M.; Weldon W.C.; O'Ryan M.G.; Bandyopadhyay A.S.; Wright P.F. Article ISI SCOPUS Clinical Infectious Diseases (2018)
Chaperone-Usher Pili Loci of Colonization Factor-Negative Human Enterotoxigenic Escherichia coli Del Canto, Felipe; O'Ryan, Miguel; Pardo, Mirka; Torres, Alexia; Gutiérrez, Daniela; Cádiz, Leandro; Valdés, Raul; Mansilla, Aquiles; Martínez, Rodrigo; Hernández, Daniela; Caro, Benjamin; Levine, Myron M.; Rasko, David A.; Hill, Christopher M.; Pop, Mihai; Stine, O. Colin; Vidal, Roberto Article ISI SCOPUS FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)
Characterization of enterotoxigenic Escherichia coli strains isolated from the massive multi-pathogen gastroenteritis outbreak in the Antofagasta region following the Chilean earthquake, 2010 Montero, David; Vidal, Maricel; Pardo, Mirka; Torres, Alexia; Kruger, Eduardo; Farfán, Mauricio; O'Ryan, Miguel; Luo, Qingwei; Fleckenstein, James; Del Canto, Felipe; Vidal, Roberto Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2017)
Exploring the relationship between polio type 2 serum neutralizing antibodies and intestinal immunity using data from two randomized controlled trials of new bOPV-IPV immunization schedules Bandyopadhyay, AS; Asturias, EJ; O'Ryan, M; Oberste, MS; Weldon, W; Clemens, R; Ruttimann, R; Modlin, JF; Gast, C Article ISI SCOPUS Vaccine (2017)
Helicobacter pylori cagA+ Is Associated with Milder Duodenal Histological Changes in Chilean Celiac Patients. Lucero, Yalda; Oyarzún, Amaya; O'Ryan, Miguel; Quera, Rodrigo; Espinosa, Nelly; Valenzuela, Romina; Simian, Daniela; Alcalde, Elisa; Arce, Claudio; Farfán, Mauricio J; Vergara, Alejandra F; Gajardo, Iván; Mendez, Jocelyn; Carrasco, Jorge; Errázuriz, Germán; Gonzalez, Mónica; Ossa, Juan C; Maiza, Eduardo; Perez-Bravo, Francisco; Castro, Magdalena; Araya, Magdalena Article Frontiers in cellular and infection microbiology (2017)
Norovirus in Latin America Systematic Review and Meta-analysis O’Ryan, Miguel; Riera-Montes, Margarita; Lopman, Benjamin Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2017)
Norovirus vaccines under development Lucero, Yalda; Vidal, Roberto; O'Ryan G, Miguel Article SCOPUS Vaccine (2017)
Parenteral protein-based rotavirus vaccine O'Ryan, Miguel; Lopman, Benjamin A Article ISI SCOPUS LANCET INFECTIOUS DISEASES (2017)
Re=> "Preparing Pediatric International Travelers for Travelers' Diarrhea=> Insights from the Global TravEpiNet". O'Ryan, Miguel; Schwartz, Eli; Ashkenazi, Shai Article The Pediatric infectious disease journal (2017)
Review: Prevalence and dynamics of Helicobacter pylori infection during childhood Zabala Torrres, Beatriz; Lucero, Yalda; Lagomarcino, Anne J.; Orellana-Manzano, Andrea; George, Sergio; Torres, Juan P.; O'Ryan, Miguel Article ISI SCOPUS HELICOBACTER (2017)
Rotavirus infection Crawford, SE; Ramani, S; Tate, JE; Parashar, UD; Svensson, L; Hagbom, M; Franco, MA; Greenberg, HB; O'Ryan, M; Kang, G; Desselberger, U; Estes, MK Article ISI SCOPUS Nature Reviews Disease Primers (2017)
Rotavirus Vaccines=> a story of success with challenges ahead. O'Ryan, Miguel Article F1000Research (2017)
The 17th International Congress on Infectious Diseases workshop on developing infection prevention and control resources for low- and middle-income countries Sastry, Sangeeta; Masroor, Nadia; Bearman, Gonzalo; Hajjeh, Rana; Holmes, Alison; Memish, Ziad; Lassmann, Britta; Pittet, Didier; Macnab, Fiona; Kamau, Rachel; Wesangula, Evelyn; Pokharel, Paras; Brown, Paul; Daily, Frances; Amer, Fatma; Torres, Jaime; O’Ryan, Miguel; Gunturu, Revathi; Bulabula, Andre; Mehtar, Shaheen Article ISI SCOPUS INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2017)
Detection of Helicobacter pylori by Real-Time PCR for 16s rRNA in Stools of NonInfected Healthy Children, Using ELISA Antigen Stool Test as the Gold Standard George, Sergio; Mamani, Nora; Lucero, Yalda; Torres, Juan Pablo; Farfán, Mauricio; Lagomarcino, Anne J; Orellana, Andrea; O'Ryan, Miguel Article ISI SCOPUS HELICOBACTER (2016)
Helicobacter pylori Infection Is Associated with Decreased Expression of SLC5A8, a Cancer Suppressor Gene, in Young Children Orellana-Manzano, Andrea; O' Ryan, Miguel; Lagomarcino, Anne; George, Sergio; Muñoz, Mindy; Mamani, Nora; Serrano, Carolina A.; Harris, Paul; Octavio, Ramilo; Asunción, Mejias; Torres, Juan; Lucero, Yalda; Quest, Andrew Article ISI SCOPUS FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2016)
Humoral and intestinal immunity induced by new schedules of bivalent oral poliovirus vaccine and one or two doses of inactivated poliovirus vaccine in Latin American infants: an open-label randomised controlled trial Asturias, Edwin J; Bandyopadhyay, Ananda S; Self, Steve; Rivera, Luis; Saez-Llorens, Xavier; Lopez, Eduardo; Melgar, Mario; Gaensbauer, James T; Weldon, William C; Oberste, M Steven; Borate, Bhavesh R; Gast, Chris; Clemens, Ralf; Orenstein, Walter; O'Ryan G, Miguel; Jimeno, José; Clemens, Sue Ann Costa; Ward, Joel; Rüttimann, Ricardo Article ISI SCOPUS LANCET (2016)
Quality assurance of medical practice in Chile: Mandatory approval of the National Board Examination in Medicine as a quality assurance to start medical practice Reyes, Humberto; Norero, Colomba; Pinto, María Eugenia; Llanos, Osvaldo; Moran, Sergio; O'Ryan, Miguel; Wolff, Marcelo Article REVISTA MEDICA DE CHILE (2016)
Rotavirus Serum IgA Immune Response in Children Receiving Rotarix Coadministered With bOPV or IPV Ramani, Sasirekha; Mamani, Nora; Villena, Rodolfo; Bandyopadhyay, Ananda S.; Gast, Chris; Sato, Alicia; Laucirica, Daniel; Clemens, Ralf; Estes, Mary K.; O’Ryan, Miguel L. Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2016)
The fecal virome of South and Central American children with diarrhea includes small circular DNA viral genomes of unknown origin Phan T.G.; da Costa A.C.; del Valle Mendoza J.; Bucardo-Rivera F.; Nordgren J.; O’Ryan M.; Deng X.; Delwart E. Article ISI SCOPUS ARCHIVES OF VIROLOGY (2016)
The human gut microbiome of Latin America populations: a landscape to be discovered Magne, Fabien; O’Ryan, Miguel L.; Vidal, Roberto; Farfan, Mauricio Article ISI SCOPUS Current Opinion in Infectious Diseases (2016)
Travelers' Diarrhea in Children What Have We Learnt? Ashkenazi, S; Schwartz, E.; O´Ryan, M Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2016)
Inactivated poliovirus vaccine given alone or in a sequential schedule with bivalent oral poliovirus vaccine in Chilean infants: a randomised, controlled, open-label, phase 4, non-inferiority study O´Ryan, M; Bandyopadhyay, AS; Villena R.; Espinoza M.; Novoa, J.; Weldon, WC; Oberste, MS; Self, S; Borate, BR; Asturias, EJ; Clemens R.; Orenstein, W; Jimeno, J; Ruttimann R.; Clemens, SAC Article ISI SCOPUS The Lancet Infectious Diseases (2015)
Persistent and Transient Helicobacter pylori Infections in Early Childhood O'Ryan, ML; Lucero, Y; Rabello, M; Mamani, N; Salinas, AM; Peña A; Torres-Torreti, JP; Mejias, A; Ramilo O; Suarez, N; Reynolds, HE; Orellana, A; Lagomarcino, AJ Article ISI SCOPUS Clinical Infectious Diseases (2015)
Seroconversión frente a primovacunación reforzada contra hepatitis B en niños con cáncer Rodolfo Villena; Marcela Zubieta; Carmen Hurtado; Carmen Salgado; Gladys Silva; Jazmine Fernández; Milena Villarroel; Marisol Fernández; Javier Brahm; MIGUEL O'RYAN; María Elena Santolaya Article SCIELO SCOPUS Revista chilena de pediatría (2015)
Position paper of the Chilean Academy of Medicine about relations between medical doctors and the industry provider on health topics] Armas, Rodolfo; Beca, Juan Pablo; Heerlein, Andres; O'Ryan, Miguel; Reyes, Humberto; Rodriguez, Juan Adolfo Article REVISTA MEDICA DE CHILE (2014)
Dynamics of Helicobacter pylori Detection in Stools During the First 5 Years of Life in Chile, a Rapidly Developing Country O'Ryan, ML; Rabello, M; Cortes, H; Lucero, Y; Peña A; Torres, JP Article ISI SCOPUS Pediatric Infectious Disease Journal (2013)
Persistence of antibodies in adolescents 18-24 months after immunization with one, two, or three doses of 4CMenB meningococcal serogroup B vaccine Santolaya, ME; O'Ryan, ML; Valenzuela, MT; PRADO, V; Vergara, RF; MuÑoz A.; Toneatto, D; Grana, G; Wang, HJ; Dull, PM Article ISI SCOPUS Human Vaccines and Immunotherapeutics (2013)
Prospective Validation of a Risk Prediction Model for Severe Sepsis in Children With Cancer and High-risk Febrile Neutropenia Santolaya, ME; Alvarez, AM; Aviles, CL; Becker, A; Venegas, M; O´Ryan, M; Salgado, C.; Topelberg S.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M; De La Maza, V; Vergara A.; Farfan MJ; Torres, JP Article ISI SCOPUS Pediatric Infectious Disease Journal (2013)
A third gyrovirus species in human faeces Phan T.G.; Li L.; O'Ryan M.G.; Cortes, H; Mamani, N; Bonkoungou I.J.O.; Wang C.; Leutenegger C.M.; Delwart E. Article ISI SCOPUS Journal of General Virology (2012)
Acute Diarrhea in West African Children: Diverse Enteric Viruses and a Novel Parvovirus Genus Phan T.G.; Vo N.P.; Bonkoungou I.J.O.; Kapoor, A.; Barro N.; O´Ryan, M; Kapusinszky B.; Wang C.; Delwart E. Article ISI SCOPUS Journal of Virology (2012)
Brote de gastroenteritis aguda en la Región de Antofagasta,Chile: 2010 Janepsy Diaz T.; VERONICA SOLARI G; Omar Caceres C.; Silvia Baeza P.; Javier Mena A.; Ximena Munoz U.; Miguel O'Ryan G; Nora Mamani M; Hector Galeno A.; Aurora Maldonado B. Article SCIELO SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2012)
Can we defeat meningococcal disease in low and middle income countries? Greenwood B.; Chiarot E.; MacLennan C.A.; O´Ryan, M Article ISI SCOPUS Vaccine (2012)
Clinical development, registration, and introduction of human rotavirus vaccine: The Latin American experience Perez Schael I.; O´Ryan, M; SÃ¡ez-Llorens X.; Linhares A.C.; VelÃ¡zquez F.R.; Colindres R.E.; Breuer T.; Ortega-Barria E. Article SCOPUS Trials in Vaccinology (2012)
Enteric viruses in wastewaters: an interesting approach to evaluate the potential impact of rotavirus vaccination on viral circulation O'Ryan M.L.; Lucero, Y; Vidal, R Article ISI SCOPUS Expert Review of Vaccines (2012)
Genotipos de rotavirus aislados de niños chilenos con gastroenteritis atendidos en dos hospitales públicos: variantes virales circulantes en un país con uso limitado de vacunas anti-rotavirus Lucero, Y; Mamani, N; Cortes, H; Peña A; Vergara, R; Gallardo, M.O. Article SCIELO SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2012)
Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: a phase 2b/3 randomised, observer-blind, placebo-controlled study Santolaya M.E.; O'Ryan M.L.; Valenzuela M.T.; PRADO, V; Vergara, R; MuÑoz A.; Toneatto, D; Grana, G; Wang, H.; Clemens R.; Dull P.M. Article ISI SCOPUS The Lancet (2012)
Outbreaks of acute gastroenteritis in Antofagasta Region. Chile 2010 Díaz, J; Solari, V; Caceres, O; Mena, J.; Baeza, S; Munoz, X; O´Ryan, M; Galeno, H; Maldonado, A.; Mamani, N Article ISI REVISTA CHILENA DE INFECTOLOGIA (2012)
Rotavirus genotypes in children with gastroenteritis assisted in two public hospitals from Chile: viral strains circulating in a country without a universal vaccination against rotavirus Lucero, Y; Mamani, N; Cortes, H; Peña A; Vergara, R; O´Ryan, M Article ISI REVISTA CHILENA DE INFECTOLOGIA (2012)
The most probable number of blocks for the partitions of the set of codons could have determined the number of standard amino acids Salinas, D.G.; Gallardo, M.O.; Osorio M.I. Article ISI SCOPUS BioSystems (2012)
Development and validation of a microarray for the confirmation and typing of norovirus RT-PCR products Mattison K.; Corneau N.; Berg I.; Bosch, A.; Duizer E.; Gutierrez-Aguirre, I; L'Homme Y.; Lucero, Y; Luo, ZY; Martyres A.; Myrmel M.; O´Ryan, M; Pagotto F.; Sano D.; Svraka S.; Urzua, U; Bidawid S. Article ISI SCOPUS JOURNAL OF VIROLOGICAL METHODS (2011)
Diagnosis of Bacteremia in Febrile Neutropenic Episodes in Children With Cancer Microbiologic and Molecular Approach Santolaya, ME; Farfan MJ; De La Maza, V; Cociña M; santelices F; Alvarez, AM; Aviles, CL; Becker, A; O´Ryan, M; Roman, P.; Salgado, C.; Silva P.; Topelberg S.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M; Torres, JP Article ISI SCOPUS Pediatric Infectious Disease Journal (2011)
Rotarix (R): vaccine performance 6 years postlicensure O´Ryan, M; Lucero, Y; Linhares, AC Article ISI SCOPUS EXPERT REVIEW OF VACCINES (2011)
Impact of the Novel Influenza A (H1N1) during the 2009 Autumn-Winter Season in a Large Hospital Setting in Santiago, Chile Torres, JP; O´Ryan, M; Herve, B; Espinoza, R.; Acuna, G.; Manalich, J; Chomali, M Article ISI SCOPUS Clinical Infectious Diseases (2010)
Prospective Characterization of Norovirus Compared With Rotavirus Acute Diarrhea Episodes in Chilean Children O'Ryan, ML; Peña A; Vergara, R; Díaz, J; Mamani, N; Cortes, H; Lucero, Y; Vidal, R; Osorio G.; Santolaya, ME; Hermosilla, G; Prado, VJ Article ISI SCOPUS Pediatric Infectious Disease Journal (2010)
Risk Factors Associated With Invasive Fungal Disease in Children With Cancer and Febrile Neutropenia A Prospective Multicenter Evaluation Villarroel M.; Aviles, CL; Silva P.; guzman AM; Poggi, H; Alvarez, AM; Becker, A; O´Ryan, M; Salgado, C.; Topelberg S.; Tordecilla, J; Varas, M; Viviani T; Zubieta, M; Santolaya, ME Article ISI SCOPUS Pediatric Infectious Disease Journal (2010)
Human bocavirus: Studies in the literature and in Chile Moreno C.; Solis, Y; O´Ryan, M Article ISI REVISTA CHILENA DE INFECTOLOGIA (2009)
Norovirus Illness Is a Global Problem: Emergence and Spread of Norovirus GII.4 Variants, 2001-2007 Siebenga, JJ; Vennema, H; Zheng, DP; Vinje, J; Lee, BE; Pang, XL; Ho, ECM; Lim, W.; Choudekar, A; Broor S.; Halperin, T; Rasool, NBG; Hewitt J.; Greening, GE; Jin M.; Duan, ZJ; Lucero, Y; O´Ryan, M; Hoehne, M; Schreier, E; Ratcliff, RM; White, PA; Iritani, N; Reuter, G; Koopmans, M Article ISI SCOPUS JOURNAL OF INFECTIOUS DISEASES (2009)
Symptomatic and Asymptomatic Rotavirus and Norovirus Infections During Infancy in a Chilean Birth Cohort O'Ryan, ML; Lucero, Y; PRADO, V; Santolaya, ME; Rabello, M; Solis, Y; Berrios, D; O'Ryan-Soriano, MA; Cortes, H; Mamani, N Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2009)
The Ever-Changing Landscape of Rotavirus Serotypes O´Ryan, M Article ISI SCOPUS Pediatric Infectious Disease Journal (2009)
Differential time to positivity and quantitative cultures for noninvasive diagnosis of catheter-related blood stream infection in children Acuña M.; O´Ryan, M; Cofre J.; Álvarez I.; Benadof, D; Rodríguez, P.; Torres, MT; Aguilera L.; Santoloya, ME Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2008)
Efficacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in Latin American infants: a randomised, double-blind, placebo-controlled phase III study Linhares, AC; Velazquez, FR; Perez Schael I.; Saez-Llorens, X; Abate, H; Espinoza F.; Lopez, P; Macias-Parra, M; Ortega-Barria, E; Rivera-Medina, DM; Rivera, L.; Pavia-Ruz, N; Núñez E.; Damaso, S; Ruiz-Palacios, GM; De Vos B; O´Ryan, M; Gillard, P; Bouckenooghe, A Article ISI SCOPUS LANCET (2008)
Human papillomavirus vaccine. Statement of the Advisory Committee of Immunizations on Behalf of the Chilean Infectious Diseases Society. September 2008 Abarca K.; Valenzuela, MT; Vergara, R; Luchsinger, V.; MuÑoz A.; de la Jimenez, J; Ripoll, E; O´Ryan, M Article ISI REVISTA MEDICA DE CHILE (2008)
Papillomavirus and cervical cancer in Chile O'Ryan, Miguel; Valenzuela, Maria Teresa Article REVISTA MEDICA DE CHILE (2008)
Predictors of severe sepsis not clinically apparent during the first twenty-four hours of hospitalization in children with cancer, neutropenia, and fever - A prospective, multicenter trial Santolaya, ME; Alvarez, AM; Aviles, CL; Becker, A; King, A; Mosso, C; O´Ryan, M; Paya, E; Salgado, C.; Silva P.; Topelberg S.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2008)
Admission clinical and laboratory factors associated with death in children with cancer during a febrile neutropenic episode Santolaya, ME; Alvarez, AM; Aviles, CL; Becker, A; Mosso, C; O´Ryan, M; Paya, E; Salgado, C.; Silva P.; Topelberg S.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2007)
Impact of rotavirus infections on outpatient clinic visits in Chile O´Ryan, M; Díaz, J; Mamani, N; Navarrete, M; Vallebuono, C Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2007)
Impacto de gastroenteritis severa por rotavirus en niños chilenos menores de 3 años de edad Vergara F Rodrigo; Navarrete, María S; Núñez, Ernesto; Escobar, Lorena; Navarro G, Sofía; Venegas E, Guillermo; Schuffeneger, Patricia; O’Ryan, Miguel Article SCIELO REVISTA MEDICA DE CHILE (2007)
Incidence of severe rotavirus gastroenteritis among Chilean children under three years of age Vergara, R; Navarrete MS; Núñez E.; Escobar, L; Navarro, S; Venegas G.; Schuffeneger, P; O´Ryan, M Article ISI REVISTA MEDICA DE CHILE (2007)
Rotarix (TM) (RIX4414): an oral human rotavirus vaccine O´Ryan, M Article ISI SCOPUS EXPERT REVIEW OF VACCINES (2007)
Evaluaciónde costo-efectividad de la vacuna anti-rotavirus en Chile Constenla, Dagna; O’Ryan, Miguel; Navarrete, María S; Antil, Lynn; Rheingans, Richard D Article SCIELO REVISTA MEDICA DE CHILE (2006)
Novel recombinant norovirus causing outbreaks of gastroenteritis in Santiago, Chile Vidal, R; Roessler, P; Solari, V; Vollaire, J; Jiang, X; Matson, DO; Mamani, N; PRADO, V; O'Ryan, ML Article ISI SCOPUS JOURNAL OF CLINICAL MICROBIOLOGY (2006)
Potential cost effectiveness of a rotavirus vaccine in Chile Constenla, D; O´Ryan, M; Navarrete MS; Antil, L; Rheingans, RD Article ISI REVISTA MEDICA DE CHILE (2006)
Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis Ruiz-Palacios, GM; Perez Schael I.; Velazquez, FR; Abate, H; Breuer T.; Clemens, SC; Cheuvart, B; Espinoza F.; Gillard, P; Innis, BL; Cervantes Y.; Linhares, AC; Lopez, P; Macias-Parra, M; Ortega-Barria, E; Richardson, V; Rivera-Medina, DM; Rivera, L.; Salinas B.; Pavia-Ruz, N; Salmeron, J; Ruttimann R.; Tinoco, JC; Rubio P.; Núñez E.; Guerrero, ML.; Yarzabal, JP; Damaso, S; Tornieporth, N; Saez-Llorens, X; Vergara, RF; Vesikari, T; Bouckenooghe, A; Clemens R.; De Vos B; O´Ryan, M Article ISI SCOPUS NEW ENGLAND JOURNAL OF MEDICINE (2006)
A millennium update on pediatric diarrheal illness in the developing world O’Ryan, Miguel; Prado, Valeria; Pickering, Larry K. Article SCOPUS Seminars in Pediatric Infectious Diseases (2005)
Caliciviruses and foodborne gastroenteritis, Chile Vidal, R; Solari, V; Mamani, N; Jiang, X; Vollaire, J; Roessler, P; PRADO, V; Matson, DO; O'Ryan, ML Article ISI SCOPUS EMERGING INFECTIOUS DISEASES (2005)
Clinical and epidemiological profile of intestinal intussusception among infants of Metropolitan Santiago Lucero, Y; Valenzuela, MT; O´Ryan, M Article ISI REVISTA MEDICA DE CHILE (2004)
Early hospital discharge followed by outpatient management versus continued hospitalization of children with cancer, fever, and neutropenia at low risk for invasive bacterial infection Santolaya, ME; Alvarez, AM; Aviles, CL; Becker, A; Cofre J.; Cumsille, MA; O'Ryan, ML; Paya, E; Salgado, C.; Silva P.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M Article ISI SCOPUS JOURNAL OF CLINICAL ONCOLOGY (2004)
Perfil epidemiológico y clínico de la invaginación intestinal en lactantes de la Región Metropolitana Yalda Lucero A; Mar Valenzuela B; Miguel O'Ryan G Article SCIELO REVISTA MEDICA DE CHILE (2004)
Declaración: La Sociedad Chilena de Infectología frente a la situación epidemiológica de hepatitis A en Chile Miguel O'Ryan G; M. Teresa Valenzuela B; M. Elena Santolaya De P; Katia Abarca V.; Rosanna Lagos Z; José Cofré Article SCIELO REVISTA CHILENA DE INFECTOLOGIA (2003)
Enrique Fanta Nuñez, nuevo miembro honorario de la Sociedad Chilena de Infectología Miguel O'Ryan G Article SCIELO REVISTA CHILENA DE INFECTOLOGIA (2003)
Epidemiological situation of foodborne diseases in Santiago, Chile in 1999-2000 Prado, Valeria; Solari, Veronica; Alvarez, IM; Arellano, Carolina; Vidal, Roberto; Carreno, M; Mamani, Nora; Fuentes, D; O'Ryan, Miguel Article REVISTA MEDICA DE CHILE (2002)
Infección micótica profunda en niños con cáncer, neutropenia y fiebre, en Chile Yalda Lucero A; Roberto Br; Ana Mar Alvarez P; Ana Becker K.; José Cofré; Nancy Enr; Ernesto Payá; Carmen Salgado M.; Mar Santolaya de P; Juan Tordecilla C.; M Varas P; Milena Villarroel C.; Tamara Viviani; Marcela Zubieta A.; Miguel O'Ryan G Article SCIELO REVISTA MEDICA DE CHILE (2002)
Invasive fungal infections in children with cancer, neutropenia and fever, in Chile Lucero, Yalda; Brucher, Roberto; Alvarez, Ana M; Becker, Anette; Cofré, José; Enriquez, nancy; Paya, Ernesto; Salgado,Carmen; Santolaya, Maria; Tordecilla, J; Varas, M; Villarroel, Milena; Viviani, Tamara; Zubieta, M; O'Ryan, Miguel Article REVISTA MEDICA DE CHILE (2002)
Prospective evaluation of a model of prediction of invasive bacterial infection risk among children with cancer, fever, and neutropenia Santolaya, ME; Alvarez, AM; Aviles, CL; Becker, A; Cofre J.; Enriquez, N; O´Ryan, M; Paya, E; Salgado, C.; Silva P.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M Article ISI SCOPUS CLINICAL INFECTIOUS DISEASES (2002)
Survey of foodborne diseases in the Metropolitan Area of Chile PRADO, V; Solari, V; Alvarez, IM; ARELLANO, C; Vidal, R; Carreño, M; Mamani, N; Fuentes, D; O´Ryan, M; Muñoz, V Article ISI REVISTA MEDICA DE CHILE (2002)
Cefepime in the empiric treatment of meningitis in children Saez-Llorens, X; O´Ryan, M Article ISI PEDIATRIC INFECTIOUS DISEASE JOURNAL (2001)
Prospective, multicenter evaluation of risk factors associated with invasive bacterial infection in children with cancer, neutropenia, and fever Santolaya, ME; Alvarez, AM; Becker, A; Cofre J.; Enriquez, N; O´Ryan, M; Paya, E; Pilorget, J; Salgado, C.; Tordecilla, J; Varas, M; Villarroel M.; Viviani T; Zubieta, M Article ISI SCOPUS JOURNAL OF CLINICAL ONCOLOGY (2001)
Rotavirus-associated medical visits and hospitalizations in South America: a prospective study at three large sentinel hospitals O´Ryan, M; Perez Schael I.; Mamani, N; Peña A; Salinas B.; Gonzalez G. ; González F; Matson, DO; Gómez J. Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2001)
Achievements and challenges of the expanded immunization program in the Americas Valenzuela, MT; O´Ryan, M Article ISI REVISTA MEDICA DE CHILE (2000)
Genomic and antigenic variation among rotavirus strains circulating in a large city of Argentina Espul, C; Cuello, H; Martínez N.; Centorbi, O; O´Ryan, M; Jackson L.; Campos, F; Matson, DO Article ISI SCOPUS JOURNAL OF MEDICAL VIROLOGY (2000)
Human caliciviruses are a significant pathogen of acute sporadic diarrhea in children of Santiago, Chile O'Ryan, ML; Mamani, N; Gaggero A.; AVENDANO, LF; Prieto, S; Peña A; Jiang, X; Matson, DO Article ISI SCOPUS JOURNAL OF INFECTIOUS DISEASES (2000)
Variability of human milk neutral oligosaccharides in a diverse population Erney, RM; Malone, WT; Skelding, MB; Marcon, AA; Kleman-Leyer, KM; O'Ryan, ML; Ruiz-Palacios, G; Hilty, MD; Pickering, LK; Prieto PA Article ISI SCOPUS JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2000)
Genotypic survey of recent beta-lactam-resistant pneumococcal nasopharyngeal isolates from asymptomatic children in Chile Gherardi, G; Inostroza, Jaime; O'Ryan, Miguel; Prado, Valeria; Prieto, S; Arellano,Ccarolina; Facklam, RR; Beall, B Article JOURNAL OF CLINICAL MICROBIOLOGY (1999)
Seroprevalence of Norwalk virus and Mexico virus in Chilean individuals: assessment of independent risk factors for antibody acquisition O'Ryan, Miguel; Vial, Pablo; Mamani, Nora; Jiang, Xi; Estes, Mary K; Ferrecio, Catterina; Lakkis, H; Matson, David Article CLINICAL INFECTIOUS DISEASES (1998)
Molecular epidemiology of human rotaviruses in Santiago, Chile O'Ryan, Miguel; Mamani, Nora; Avenda;o, Luis F; Cohen, Jackie; Pena, Alfredo; Villarroel, Julia; Chavez, Ana; Valdivieso, Francisca; Matson, David Article PEDIATRIC INFECTIOUS DISEASE JOURNAL (1997)
Effect of maternal rotavirus immunization on milk and serum antibody titers Pickering, Larry K; Morrow, Ardythe; Herrera, Ismael; O'Ryan, Miguel; Estes, Mary K; Guilliams, SE; Jackson, Laurie; Carter-Campbell S; Matson, David Article JOURNAL OF INFECTIOUS DISEASES (1995)
Acquisition of serum isotype-specific and G type-specific antirotavirus antibodies among children in day care centers O'Ryan ML, Matso DO, Estes MK, Pickering LK Article PEDIATRIC INFECTIOUS DISEASE JOURNAL (1994)
Acute Gastroenteritis in Latin America Prado, Valeria; O'Ryan, Miguel Article Infectious Disease Clinics of North America (1994)
Anti-rotavirus G type-specific and isotype-specific antibodies in children with natural rotavirus infections O'Ryan, Miguel; Matson, David; Estes, Mary K; Pickering, Larry K Article JOURNAL OF INFECTIOUS DISEASES (1994)
Assesment of epitope-blocking assays for measuring antibody to rotavirus Matso, David; O'Ryan, Miguel; Pickering, Larry K; Estes, May K Article Journal of Virologic Methods (1994)
Fecal antibody responses to symptomatic and asymptomatic rotavirus infections Matson, David; O'Ryan, Miguel; Herrera, Ismael; Pickering, Larry K; Estes, Mary K Article The Journal of Infectious Diseases (1993)
Characterization of serum antibody responses to natural rotavirus infections in children by VP7-specific epitope-blocking assays Matso, David; O'Ryan, Miguel; Pickering, Larry K; Chiba, S; Nakata, S; Raj, Pushkar; Estes, Mary K Article JOURNAL OF CLINICAL MICROBIOLOGY (1992)
Outbreaks of human enteric adenovirus types 40 and 41 in Houston day care centers Van, Rory; Wun, CC; O'Ryan, Miguel; Matson, David; Jackson, Laurie; Pickering, Larry K Article JOURNAL OF PEDIATRICS (1992)
Serotypes of rotavirus that infect infants symptomatically and asymptomatically Pickering, Larry K; O'Ryan, Miguel Article Advances in Experimental Medical Biology (1991)
Invasive disease due to multiply resistant Streptococcus pneumoniae in a Houston, Tex, day-care center Rauch, Alan M; O'Ryan, Miguel; Pickering, Larry K Article American Journal of Disease in Children (1990)
Molecular epidemiology of rotavirus in children attending day care centers in Houston O'Ryan, Miguel; Matson, David; Estes, Mary K; Bartlett, AV; Pickering, Larry K Article JOURNAL OF INFECTIOUS DISEASES (1990)
SARS-CoV-2 antibody prevalence in blood in a large school community subject to a Covid19 outbreak: a cross-sectional study Torres, Juan P.; Pinera, C; De La Maza, V; Lagomarcino, AJ; Simian, D; Torres, B; Urquidi, C; Valenzuela, MT; O´Ryan, M Article Q1 Journal in all databases CLINICAL INFECTIOUS DISEASES


Determination of rotavirus' serotypes in children younger than 36 months of age with acute gastroentheritis and deshydration in the Concepcion-Talcahuano area, Chile Venegas G.; Núñez E.; Alvarez A.; Mamani, N; O´Ryan, M Abstract ISI PEDIATRIC RESEARCH (2005)


Miguel O'Ryan Gallardo, nuevo miembro en la Academia de Medicina de Chile Miguel O'Ryan G Anuncio SCIELO REVISTA CHILENA DE INFECTOLOGIA (2012)


Aeromonas Species O´Ryan, M; Lucero Alvarez Y.C. BookWhole SCOPUS Principles and Practice of Pediatric Infectious Diseases: Fourth Edition (2012)
Yersinia Species Ochoa T.J.; O´Ryan, M BookWhole SCOPUS Principles and Practice of Pediatric Infectious Diseases: Fourth Edition (2012)


Reflexiones y sentimientos desde un equipo de voluntarios del Ministerio de Salud y el Colegio Médico de Chile, después del terremoto reciente Miguel O'Ryan G Comentario SCIELO REVISTA MEDICA DE CHILE (2010)


Control de calidad de los médicos que inician el ejercicio profesional en Chile: Declaración de la Academia Chilena de Medicina del Instituto de Chile Humberto Reyes B.; Colomba Norero V.; María Eugenia Pinto C; Osvaldo Llanos L.; Sergio Morán V; Miguel O'Ryan G; Marcelo Wolff R. ComunicacionBreve SCIELO SCOPUS REVISTA MEDICA DE CHILE (2016)


Pandemia y vacunas, ¿quimera o realidad? SERGIO GEORGE; Juan Pablo Torres Torreti; MIGUEL O'RYAN Editorial SCIELO REVISTA MEDICA DE CHILE (2020)
Investigación médica en Chile a la luz de la nueva legislación O’Ryan, Miguel Editorial SCIELO SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2013)
Tercer Congreso Mundial de Infectología Pediátrica: Una fiesta a la que nadie debe faltar Miguel O'Ryan G Editorial SCIELO REVISTA CHILENA DE INFECTOLOGIA (2002)


Rotavirus vaccines roll-out in resource-deprived regions O'Ryan, ML; Clemens R. EditorialMaterial ISI SCOPUS The Lancet Infectious Diseases (2015)
Potential influence of recent modifications in Chilean legislation for medical research O´Ryan, M EditorialMaterial ISI REVISTA CHILENA DE INFECTOLOGIA (2013)
Reflections and feelings from a team of volunteers from the Ministry of Health and the Chilean Medical Association, after the recent earthquake O´Ryan, M EditorialMaterial ISI REVISTA MEDICA DE CHILE (2010)
The roles that the environment, the sanitary conditions, the epidemiology and vaccines play in the challenge of infectious diseases Reply O´Ryan, M EditorialMaterial ISI REVISTA CHILENA DE INFECTOLOGIA (2010)
New rotavirus vaccines: Renewed optimism - Commentary O´Ryan, M; Matson, DO EditorialMaterial ISI SCOPUS JOURNAL OF PEDIATRICS (2006)
50 years ago in The Journal of Pediatrics - Therapy of acute purulent otitis media with dibenzylethylenediamine dipenicillin G. O´Ryan, M EditorialMaterial ISI JOURNAL OF PEDIATRICS (2004)
Meningococcal infections: With particular reference to fulminant meningococcemia (Waterhouse-Friderichsen syndrome) treated with cortisone and norepinephrine O´Ryan, M EditorialMaterial ISI JOURNAL OF PEDIATRICS (2004)


Enterovirus D68 Infection, Chile, Spring 2014 Torres, JP; Farfan MJ; Izquierdo, G; Piemonte, P; Henriquez, J.; O'Ryan, ML Letter ISI SCOPUS Emerging Infectious Diseases (2015)
Rotavirus vaccine for developing countries - Reply O´Ryan, M; Linhares, AC; Perez Schael I.; Velazquez, FR Letter ISI LANCET (2008)
Rotavirus vaccines - Reply O´Ryan, M; Ruiz-Palacios, GM; Clemens R. Letter ISI NEW ENGLAND JOURNAL OF MEDICINE (2006)
Risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157 : H7 infections. O´Ryan, M; PRADO, V Letter ISI NEW ENGLAND JOURNAL OF MEDICINE (2000)


A randomized, double-blind phase 2b study to assess the efficacy of MEDI7510 for the prevention of acute respiratory illness associated with respiratory syncytial virus in senior adults MedImmune (Protocol D4420C00005) Proyecto 2016-2017 Inv. Principal
Open Label, Controlled, Multi-Center, Extension Study to Assess the Persistence of Bactericidal Activity at 4 to 7.5 Years After Two Dose Primary Series of Novartis Meningococcal B Recombinant Vaccine... Novartis Vaccines (V72-75) Proyecto 2016-2017 Inv. Responsable
Seroprevalencia de norovirus en lactantes chilenos. Noro Epi 018 Farmcéutica Takeda (Noro epi 018) Proyecto 2015-2015 Inv. Principal
Estudio Carga de las enfermedades causadas por norovirus en niños en la comunidad y hospital, Noro-Epi002 FarmacéuticaTakeda (Noro epi 002) Proyecto 2014-2015 Inv. Principal
Estudio de Fase 4 aleatorizado abierto, para evaluar la inducción de inmunidad humoral e intestinal ante la polio luego de un esquema de tres dosis IPV comparado con dos esquemas secuenciales de IPV seguida de bOPV administrados el primer año de vida. Bill &Mellinda Gates Foundation (IPV002 ABMG) Proyecto 2013-2014 Inv. Principal
PERSISTENT HELICOBACTER PYLORI INFECTION IN APPARENTLY ASYMPTOMATIC 6-10 YEAR OLD CHILDREN=> FRIEND OR FOE? FONDECYT (1130561) Proyecto 2013-2017 Inv. Responsable
GENOMIC AND FUNCTIONAL ANALYSIS TO IDENTIFY NOVEL ADHESINS IN ENTEROTOXIGENIC ESCHERICHIA COLI STRAINS OBTAINED FROM DEVELOPING COUNTRIES FONDECYT (3130555) Proyecto 2012-2015 Inv. Patrocinante
TOWARDS A MORE RATIONAL APPROACH IN THE COMPREHENSIVE MANAGEMENT OF THE CHILD WITH CANCER, FEVER AND NEUTROPENIA=> FILLING THE GAPS. FONDECYT (1120800) Proyecto 2012-2016 Coinvestigador(a)
CARACTERIZACION GENETICA DE LOS FACTORES DE VIRULENCIA DE HELICOBACTER PYLORI ASOCIADOS CON LA COLONIZACION PERSISTENTE EN NIÃ‘OS MENORES DE 3 AÃ‘OS FONDECYT (3120139) Proyecto 2011-2013 Inv. Patrocinante
Estudio en fase 2b/3, multicéntrico, de extención del V72P10 para evaluar la persistencia de anticuerpos al cabo de 18 meses después de completado el esquema de vacunación del estudio V71P10. Novartis Vaccines (V72P10E1) Proyecto 2010-2012 Inv. Principal
HELICOBACTER PYLORI COLONIZATION DURING THE FIRST THREE YEARS OF LIFE=> BACTERIAL AND HOST FACTORS ASSOCIATED WITH PERSISTENT COLONIZATION. FONDECYT (1100514) Proyecto 2010-2013 Inv. Responsable
PERFILES TRANSCRIPCIONALES Y DIAGNOSTICO MICROBIOLOGICO MOLECULAR PARA AVANZAR EN EL DIAGNOSTICO DE SEPSIS Y EN LA IDENTIFICACION DEL MICROORGANISMO CAUSAL EN NIQOS CON CANCER, NEUTROPENIA Y FIEBRE FONDECYT (1090194) Proyecto 2009-2012 Coinvestigador(a)
ROTAVIRUS Y CALICIVIRUS HUMANOS=> AVANZANDO EN LA IDENTIFICACION DE FACTORES ASOCIADOS AL PATOGENO Y AL HOSPEDERO QUE DETERMINAN SUSCEPTIBILIDAD Y SEVERIDAD DE INFECCION EN POBLACION CHILENA. FONDECYT (7090065) Proyecto 2009-2010 Inv. Responsable
Estudio controlado de fase 2b/3, multicéntrico y ciego para el observador, sobre seguridad, tolerabilidad e inmunogenicidad de la Vacuna Meningocócica Recombinante de Novartis administrada aadolescentes sanos entre 11 – 17 años. Novartis Vaccines (V72P10) Proyecto 2008-2010 Inv. Principal
Inserción Productiva y Sustentable de Graduados de Excelencia de los Programas de Doctorado en Ciencias Médicas y Biomédicas a Centros de Investigación Clínica Avanzada (CICA). MECESUP (UCH0608) Proyecto 2007-2011 Inv. Principal
ROTAVIRUS Y CALICIVIRUS HUMANOS=> AVANZANDO EN LA IDENTIFICACION DE FACTORES ASOCIADOS AL PATOGENO Y AL HOSPEDERO QUE DETERMINAN SUSCEPTIBILIDAD Y SEVERIDAD DE INFECCION EN POBLACION CHILENA. FONDECYT (1061079) Proyecto 2006-2010 Inv. Responsable
PREDICCION DE RIEGO DE SEPSIS EN NINOS CON CANCER, NEUTROPENIA Y FIEBRE. UN PASO NECESARIO PARA PROPONER ESTRATEGIAS DE MENEJO SELECTIVO EN PACIENTES DE ALTO RIESGO. FONDECYT (1040907) Proyecto 2004-2007 Coinvestigador(a)


Documento de la Academia Chilena de Medicina sobre las relaciones entre los médicos y la industria proveedora en salud Rodolfo Armas; Juan Pablo Beca; Andrés Heerlein; MIGUEL O'RYAN; Humberto Reyes; José Adolfo Rodríguez Report SCIELO REVISTA MEDICA DE CHILE (2014)


Transdisciplinary research before, during and after COVID-19 vaccination in Chile: a virtuoso collaboration with future perspectives Torres, Juan Pablo; Basso, Leonardo; Saure, Denis; Zuniga, Marcela; Couve, Andres; Farfan, Mauricio; de la Maza, Veronica; Campos, Nelson; O'Ryan, Miguel Review ISI FRONTIERS IN PUBLIC HEALTH (2024)
Two centuries of vaccination: historical and conceptual approach and future perspectives Montero, David A.; Vidal, Roberto M.; Velasco, Juliana; Carreno, Leandro J.; Torres, Juan P.; Benachi, O. Manuel A.; Tovar-Rosero, Yenifer-Yadira; Onate, Angel A.; O'Ryan, Miguel Review ISI FRONTIERS IN PUBLIC HEALTH (2024)
Bacterial Gut Microbiota and Infections During Early Childhood George, Sergio; Aguilera, Ximena; Gallardo, Pablo; Farfan, Mauricio; Lucero, Yalda; Torres, Juan Pablo; Vidal, Roberto; O'Ryan, Miguel Review ISI FRONTIERS IN MICROBIOLOGY (2022)
Norovirus: Facts and Reflections from Past, Present, and Future Lucero, Yalda; Matson, David O.; Ashkenazi, Shai; George, Sergio; O'Ryan, Miguel Review ISI VIRUSES-BASEL (2021)
Gastric Damage and Cancer-Associated Biomarkers in Helicobacter pylori-Infected Children George, S; Lucero, Y; Torres, JP; Lagomarcino, AJ; O'Ryan, M Review ISI (2020)
Norovirus and Rotavirus Disease Severity in Children: Systematic Review and Meta-analysis Riera-Montes, M; ORyan, M; Verstraeten, T Review ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2018)
Human rotavirus vaccine (Rotarix): focus on effectiveness and impact 6 years after first introduction in Africa O´Ryan, M; Giaquinto, C; Benninghoff, B Review ISI SCOPUS Expert Review of Vaccines (2015)
The current situation of meningococcal disease in Latin America and updated Global Meningococcal Initiative (GMI) recommendations Safadi, MAP; O'Ryanh, M; Bravo, MTV; Brandileone, MCC; Gonad, MCO; de Lemos, APS; Moreno G.; Vazquez, JA; Lopez, EL; Taha, MK; Borrow, R Review ISI SCOPUS Vaccine (2015)
Vaccination with a multicomponent meningococcal B vaccine in prevention of disease in adolescents and young adults Nolan, T; O´Ryan, M; Wassil, J; Abitbol, V; Dull, P Review ISI SCOPUS Vaccine (2015)
Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part I: Overview, vaccines for enteric viruses and Vibrio cholerae O´Ryan, M; Vidal, R; Del Canto, F; Salazar, JC; Montero D. Review ISI SCOPUS Human Vaccines and Immunotherapeutics (2015)
Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part II: Vaccines for Shigella, Salmonella, enterotoxigenic E. coli (ETEC) enterohemorragic E. coli (EHEC) and Campylobacter jejuni O´Ryan, M; Vidal, R; Del Canto, F; Salazar, JC; Montero D. Review ISI SCOPUS Human Vaccines and Immunotherapeutics (2015)
A Multi-Component Meningococcal Serogroup B Vaccine (4CMenB): The Clinical Development Program O´Ryan, M; Stoddard J.; Toneatto, D; Wassil, J; Dull, PM Review ISI SCOPUS DRUGS (2014)
Management of acute infectious diarrhea for children living in resource-limited settings O´Ryan, M; Ashkenazi-Hoffnung, L; O'Ryan-Soriano, MA; Ashkenazi, S Review ISI SCOPUS EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2014)
An update on management of severe acute infectious gastroenteritis in children O´Ryan, M; Lucero, Y; O'Ryan-Soriano, MA; Ashkenazi, S Review ISI SCOPUS Expert Review of Anti-Infective Therapy (2010)
Rotavirus vaccines for the developing world O'Ryan, ML; Hermosilla, G; Osorio G. Review ISI SCOPUS Current Opinion in Infectious Diseases (2009)
Update on Rotarix (TM): an oral human rotavirus vaccine O´Ryan, M; Linhares, AC Review ISI SCOPUS Expert Review of Vaccines (2009)
New rotavirus vaccines: a reality at last [Vacunas anti-rotavirus: al fin una realidad.] O´Ryan, M Review SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2005)
Two year review of intestinal intussusception in six large public hospitals of Santiago, Chile O´Ryan, M; Lucero, Y; Peña A; Valenzuela, MT Review ISI PEDIATRIC INFECTIOUS DISEASE JOURNAL (2003)

148

Miguel O'Ryan

Profesor Titular

Programa de Microbiologia y Micologia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Yalda Lucero

Profesor Asistente

Programa de Microbiología y Micología; Departamento de Pediatría y Cirugía infantil;

DIVISIÓN NORTE, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE, DEPARTAMENTO DE PEDIATRÍA Y CIRUGÍA INFANTIL-HOSPITAL LUIS CALVO MACKENNA

Santiago, Chile

roberto vidal

Head of Pathogenic Escherichia coli Laboratory

Director Microbiology and Mycology Program

UNIVERSIDAD DE CHILE

Santiago, Chile

Milena Villarroel

JEFE CENTRO DE RESPONSABILIDAD

PEDIATRIA

HOSPITAL LUIS CALVO MACKENNA

Santiago, Chile

Mauricio Farfán

Profesor Asociado

Departamento de Pediatria y Cirugia Infantil, Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile

Universidad de Chile

Providencia, Chile

Felipe Del Canto

Profesor Asistente

Programa de Microbiologia y Micologia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Sergio George

Tesista Doctorado en Ciencias Médicas y Especialidad en Pediatría

Facultad de Medicina

Universidad de Chile

Santiago, Chile

David Montero

Profesor Asistente

Microbiología

Universidad de Concepción

Concepción, Chile

Maria Valenzuela

VICEDECANA DE INVESTIGACION Y POSTGRADO

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

Rodrigo Vergara

Profesor titular de pediatría y preclínicas

Pediatría y Preclínicas

Universidad de Valparaíso

Viña del Mar, Chile

Marcela Rabello

pediatra infectologa

Pediatria

Hospital Dr Luis Calvo Mackenna

Santiagoa, Chile

Alvaro Muñoz

Profesor Titular

Universidad San Sebastián

Santiago, Chile

Leandro Cadiz

Jefe Técnico

Patología Animal

Universidad de Chile

Santiago, Chile

Pablo Román

Profesor Asistente

Departamento de Ingeniería Informática

Universidad de Santiago de Chile

Santiago, Chile

MARIA NAVARRETE

Profesora

Medicina

Universidad de Santiago de Chile

Santiago, Chile

Juan Pablo Torres

Jefe Unidad de Investigación Clínica

Pediatría y Cirugía Infantil Oriente

UNIVERSIDAD DE CHILE

Santiago, Chile

Daniela Gutiérrez

Encargada de laboratorio Ingeniería sanitaria

Ingeniería

Universidad de Santiago de Chile

Santiago, Chile

Veronica De la Maza

Profesor academico

Pediatra y Cirugía

Universidad de Chile

Santiago, Chile

Mindy Muñoz

Investigadora Postdoctoral

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

Carolina Serrano

Profesor Asistente Ordinario

Pediatric Gastroenterology and Nutrition

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Manuel Osorio

Docente

Medicina

UNIVERSIDAD DIEGO PORTALES

Santiago, Chile

Mauricio Gallardo

Profesor

Biofísica

UNIVERSIDAD DIEGO PORTALES

Santiago, Chile

Dino Salinas

., Chile

Felipe Santelices

Instructor Adjunto

Neonatología

Universidad Católica de Chile

Santiago, Chile

Maria Santolaya

Pediatra infectologa, Profesor titular

Pediatria, Campus Oriente

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, DEPARTAMENTO DE PEDIATRÍA ORIENTE

Santiago, Chile

JORGE QUENSE

Associate professor

Geohraphy

PONTIFICAL CATHOLIC UNIVERSITY OF CHILE, INSTITUTE OF GEOGRAPHY

Santiago, Chile

ULISES URZUA

Assistant Professor

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

Beatriz Zabala

Profesor Asistente

Salud

Universidad de Aysén

Coyhaique, Chile

Helena Poggi

Coordinadora de Investiagción

División de Pediatría

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Mirta Acuña

Lider del Programa de Uso racional de Antimicrobianos

Infectología

HOSPITAL ROBERTO DEL RÍO

Santiago, Chile

VIVIAN LUCHSINGER

Profesor Asociado

Virología

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA.

Santiago, Chile

KATIA ABARCA

Profesor Titular

Pediatría

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Ximena Muñoz

Profesional Especialidades Entomología Médica

Departamento Laboratorio de Salud Pública, Ambiental y Laboral

Secretaria Regional Ministerial de Salud

Arica, Chile

Fabien MAGNE

Profesor asistante

UNIVERSIDAD DE CHILE

Chile

Juan Salazar

Profesor Asociado

Instituto de Ciencias Biomédicas

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

Ana Guzman

MÉDICO JEFE LABORATORIO

LABORATORIO CLÍNICO

PONTIFICIA UNIVERSIDAD CATÓLICA

SANTAIGO, Chile

Aldo Gaggero

Académico. Profesor Asociado.

Virología

ICBM. FACULTAD DE MEDICINA. UNIVERSIDAD DE CHILE.

Santiago, Chile

Miguel O'Ryan

Líneas de Investigación

Educación

Médico Pediatra , PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1987

Infectologo Pediatra, University of Texas Health Science Center at Houston. Estados Unidos, 1991

Experiencia Profesional

Presidente Part Time

Sub Director Part Time

Director Part Time

Director Part Time

Integrante Part Time

Vicerrector de Investigacion y Desarrollo Full Time

Sub Director de Inovacion Part Time

Miembro de Numero Other

Director de Investigacion y Tecnologia Part Time

Director de relaciones Internacionales Part Time

Vice Presidente Part Time

Investigador Asociado Part Time

Decano Full Time

Formación de Capital Humano

Premios y Distinciones

Miguel O´Ryan Gallardo

Miguel O´Ryan Gallardo

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