Man

Felipe Antonio Del Canto Fuentes

Profesor Asistente

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Líneas de Investigación


Microbiology; Molecular Biology; Bacterial Pathogenesis; Virulence factors, Bacterial colonization; Adhesins; Genome sequencing; Comparative genomics; Anti-virulence therapies; Vaccine development.

Educación

  •  Microbiologia, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2011
  •  Biochemist, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2004
  •  Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2004

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Facultad de Medicina

    Santiago, Chile

    2013 - At present

Experiencia Profesional

  •   Profesor Asistente Full Time

    Universidad de Chile

    Santiago, Chile

    2013 - At present


 

Article (23)

Immunization of mice with chimeric antigens displaying selected epitopes confers protection against intestinal colonization and renal damage caused by Shiga toxin-producing Escherichia coli

Montero, David A.; Del Canto, Felipe; Salazar, Juan C.; Cespedes, Sandra; Cadiz, Leandro; Arenas-Salinas, Mauricio; Reyes, Jose; onate, angel; Vidal, Roberto M.

Article ISI SCOPUS
NPJ VACCINES  (2020)

The Role of the Flagellar Protein FlgJ in the Virulence of Brucella abortus

Coloma-Rivero, Roberto F.; Gomez, Leonardo; Alvarez, Francisco; Saitz, Waleska; del Canto, Felipe; Cespedes, Sandra; Vidal, Roberto; Onate, Angel A.

Article ISI
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  (2020)

Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS)

Vidal, Roberto; Muhsen, Khitam; Tennant, Sharon M; Svennerholm, Ann-Mari; Sow, Samba O; Sur, Dipika; ...Del Canto, Felipe (43)

Article
PLOS NEGLECTED TROPICAL DISEASES  (2019)

Comparative genomic analysis and molecular examination of the diversity of enterotoxigenic Escherichia coli isolates from Chile

Rasko, David A.; del Canto, Felipe; Luo, Qingwei; Fleckenstein, James M.; Vidal, Roberto; Hazen, Tracy H.; Torres, Alfredo G.

Article ISI SCOPUS
PLOS NEGLECTED TROPICAL DISEASES  (2019)

Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli

Kuhlmann, F. Matthew; Martin, John; Hazen, Tracy H.; Vickers, Tim J.; Pashos, Madeline; Okhuysen, Pablo C.; Gómez-Duarte, Oscar G.; Cebelinski, Elizabeth; Boxrud, Dave; del Canto, Felipe; Vidal, Roberto; Qadri, Firdausi; Mitreva, Makedonka; Rasko, David A.; Fleckenstein, James M.; Torres, Alfredo G

Article ISI SCOPUS
PLOS NEGLECTED TROPICAL DISEASES  (2019)

Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxin-producing Escherichia coli strains

Montero, David A*; Del Canto, Felipe*; Velasco, Juliana=> Colello; Rocío, Padola; Nora L, Salazar; Juan Carlos, San Martin; Carla, Oñate; Ángel, Blanco; Jorge, Rasko; David A, Contreras; Carmen, Puente; José Luis, Scheutz; Flemming, Franz; Eelco, Vidal; Roberto M. (* autores que contribuyeron igualmente, ver pdf)

Article
EMERGING MICROBES AND INFECTIONS  (2019)

Genome and Functional Characterization of Colonization Factor Antigen I- and CS6-Encoding Heat-Stable Enterotoxin-Only Enterotoxigenic Escherichia coli Reveals Lineage and Geographic Variation

Hazen, TH; Nagaraj, S; Sen, S; Permala-Booth, J; Del Canto, F; Vidal, R; Barry, EM; Bitoun, JP; Chen, WH; Tennant, SM; Rasko, DA

Article ISI SCOPUS
MSYSTEMS  (2019)

Identification and detection of iha subtypes in LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from humans, cattle and food

Colello R.; Krüger A.; Velez M.V.; Del Canto F.; Etcheverría A.I.; Vidal R.; Padola N.L.

Article ISI SCOPUS
HELIYON  (2019)

Predominance of Rotavirus G8P[8] in a City in Chile, a Country Without Rotavirus Vaccination

Lucero, Y; O'Ryan, M; Liparoti, G; Huerta, N.; Mamani, N; Ramani, S; Lagomarcino, AJ; Del Canto, F; Quense, J

Article ISI SCOPUS
JOURNAL OF PEDIATRICS  (2019)

Coli Surface Antigen 26 Acts as an Adherence Determinant of Enterotoxigenic Escherichia coli and Is Cross-Recognized by Anti-CS20 Antibodies

Cadiz, Leandro; Torres, Alexia; Valdes, Raul; Vera, Gabriel; Gutierrez, Daniela; Levine, Myron M.; Montero, David A.; O'Ryan, Miguel; Rasko, David A.; Stine, O. Colin; Vidal, Roberto; del Canto, Felipe

Article ISI SCOPUS
FRONTIERS IN MICROBIOLOGY  (2018)

First report of the distribution of Locus of Adhesion and Autoaggregation (LAA) pathogenicity island in LEE-negative Shiga toxin-producing Escherichia coli isolates from Argentina

Colello, Rocio; Victoria Velez, Maria; Gonzalez, Juliana; Montero, David A.; Bustamante, Ana V.; del Canto, Felipe; Etcheverria, Analia I.; Vidal, Roberto; Lia Padola, Nora

Article ISI SCOPUS
MICROBIAL PATHOGENESIS  (2018)

Chaperone-Usher Pili Loci of Colonization Factor-Negative Human Enterotoxigenic Escherichia coli

Del Canto, Felipe; O'Ryan, Miguel; Pardo, Mirka; Torres, Alexia; Gutiérrez, Daniela; Cádiz, Leandro; Valdés, Raul; Mansilla, Aquiles; Martínez, Rodrigo; Hernández, Daniela; Caro, Benjamin; Levine, Myron M.; Rasko, David A.; Hill, Christopher M.; Pop, Mihai; Stine, O. Colin; Vidal, Roberto

Article ISI SCOPUS
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  (2017)

Characterization of enterotoxigenic Escherichia coli strains isolated from the massive multi-pathogen gastroenteritis outbreak in the Antofagasta region following the Chilean earthquake, 2010

Montero, David; Vidal, Maricel; Pardo, Mirka; Torres, Alexia; Kruger, Eduardo; Farfán, Mauricio; O'Ryan, Miguel; Luo, Qingwei; Fleckenstein, James; Del Canto, Felipe; Vidal, Roberto

Article ISI SCOPUS
INFECTION GENETICS AND EVOLUTION  (2017)

Genetic Diversity and Virulence Determinants of Escherichia coli Strains Isolated from Patients with Crohn's Disease in Spain and Chile

Quera, Rodrigo; De la Fuente, Marjorie; Hermoso, MA; Céspedes, S; Saitz, W; Del Canto, F; de la Fuente, M; Muñoz, M; Ginard, D; Khorrami, S; Giron, J; Rossello-Mora, R; Vidal, R

Article ISI SCOPUS
FRONTIERS IN MICROBIOLOGY  (2017)

Locus of Adhesion and Autoaggregation (LAA), a pathogenicity island present in emerging Shiga Toxin-producing Escherichia coli strains

Montero D.A.; Velasco J.; Del Canto F.; Puente J.L.; Padola N.L.; Rasko D.A.; Farfán M.; Salazar J.C.; Vidal R.

Article ISI SCOPUS
SCIENTIFIC REPORTS  (2017)

Emergence of Plasmid-Borne dfrA14 Trimethoprim Resistance Gene in Shigella sonnei

Miranda, A; Avila, B; Diaz, P; Rivas, L; Bravo, K; Astudillo, J; Bueno, C; Ulloa, MT; Hermosilla, G; Del Canto, F; Salazar, JC; Toro, CS

Article ISI SCOPUS
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  (2016)

Vaccination with DNA Encoding Truncated Enterohemorrhagic Escherichia coil (EHEC) Factor for Adherence-1 Gene (efa-1') Confers Protective Immunity to Mice Infected with E. coil O157:H7

Riquelme-Neira, R; Rivera A.; Sáez D; Fernández P.; Osorio G.; Del Canto, F; Salazar, JC; Vidal, RM; Oñate A.

Article ISI
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  (2016)

Neisseria meningitidis ST-11 Clonal Complex, Chile, 2012

Araya, P; Fernandez, J; Del Canto, F; Seoane, M.; Ibarz-Pavon A.B.; barra, g; Pidal, P; Díaz, J; Hormazábal J.C.; Valenzuela M.T.

Article ISI SCOPUS
EMERGING INFECTIOUS DISEASES  (2015)

TleA, a Tsh-Like Autotransporter Identified in a Human Enterotoxigenic Escherichia coli Strain

Gutiérrez D.; PARDO, M; Montero D.; Oñate A.; Farfan MJ; Ruiz-Perez, F; Del Canto, F; Vidal, R

Article ISI SCOPUS
Infection and Immunity  (2015)

Immunoproteomic Analysis To Identify Shiga Toxin-Producing Escherichia coli Outer Membrane Proteins Expressed during Human Infection

Montero D.; Orellana P.; Gutiérrez D.; Araya D.; Salazar, JC; PRADO, V; Oñate A.; Del Canto, F; Vidal, R

Article ISI SCOPUS
INFECTION AND IMMUNITY  (2014)

Identification of Coli Surface Antigen 23, a Novel Adhesin of Enterotoxigenic Escherichia coli

Del Canto, F; Botkin D.J.; Valenzuela P.; Popov, V.; Ruiz-Perez, F; Nataro J.P.; Levine M.M.; Stine O.C.; Pop M.; Torres A.G.; Vidal, R

Article ISI SCOPUS
Infection and Immunity  (2012)

Distribution of Classical and Nonclassical Virulence Genes in Enterotoxigenic Escherichia coli Isolates from Chilean Children and tRNA Gene Screening for Putative Insertion Sites for Genomic Islands

Del Canto, F; Valenzuela P.; Cantero, L; Bronstein J.; Blanco, JE; Blanco, J; PRADO, V; LeVine, M.; Nataro J.; Sommerfelt, H; Vidal, R

Article ISI SCOPUS
Journal of Clinical Microbiology  (2011)

Features of natural and gonadotropin-releasing hormone antagonist-induced corpus luteum regression and effects of in vivo human chorionic gonadotropin

Del Canto, F; Sierralta W.; Kohen P.; MuÑoz A.; Strauss, JF; Devoto L.

Article ISI SCOPUS
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM  (2007)

BookSection (1)

Colonization factors of enterotoxigenic Escherichia coli

Del Canto, Felipe; Torres, Alfredo G.; Morabito, Stefano

BookSection
 (2014)

Proyecto (5)

Surface-exposed domains of pili ushers as binding sites for antibodies and proinflammatory cytokines: Impact on pili assembly, adherence capacity and virulence of pathogenic Escherichia coli

Del Canto, Felipe; Vidal, Roberto; Lucero, Yalda; Arenas Mauricio; Onate, Angel

Proyecto
 (2020)

Immune response and gastric damage transition from child to adult in symptomatic Helicobacter pylori infected individuals=> dynamic and host/pathogen/microbiota determinants

FONDECYT (1190456)

Proyecto
2019-2022
Coinvestigador(a)

Formulation of chimeric proteins as a strategy to develop a novel vaccine against Shiga-toxin producing Escherichia coli (STEC)

FONDEF (ID16I10140)

Proyecto
2017-2018
Investigador(a)

CHARACTERIZATION OF NEW GENETIC MARKERS ENCODED WITHIN AN UNDESCRIBED LOCUS OF ADHERENCE AND AUTOAGGREGATION (LAA) PRESENT IN EMERGING CLINICALLY RELEVANT SHIGA TOXIN-PRODUCING E.COLI STRAINS.

FONDECYT (1161161)

Proyecto
2016-2020
Coinvestigador(a)

IDENTIFICATION OF NOVEL CROSS-ANTIGENS AMONG CHAPERONE-USHER PILI COMPONENTS AS TARGETS TO PREVENT ADHESION OF GRAM-NEGATIVE BACTERIAL PATHOGENS

FONDECYT (11150966)

Proyecto
2015-2018
Inv. Responsable

Review (2)

Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part I: Overview, vaccines for enteric viruses and Vibrio cholerae

O´Ryan, M; Vidal, R; Del Canto, F; Salazar, JC; Montero D.

Review ISI SCOPUS
Human Vaccines and Immunotherapeutics  (2015)

Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part II: Vaccines for Shigella, Salmonella, enterotoxigenic E. coli (ETEC) enterohemorragic E. coli (EHEC) and Campylobacter jejuni

O´Ryan, M; Vidal, R; Del Canto, F; Salazar, JC; Montero D.

Review ISI SCOPUS
Human Vaccines and Immunotherapeutics  (2015)

25
Felipe Del Canto

Profesor Asistente

Programa de Microbiologia y Micologia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

18
roberto vidal

Head of Pathogenic Escherichia coli Laboratory

Director Microbiology and Mycology Program

UNIVERSIDAD DE CHILE

Santiago, Chile

9
David Montero

Profesor Asistente

Microbiología

Universidad de Concepción

Concepción, Chile

6
Miguel O'Ryan

Profesor Titular

Programa de Microbiologia y Micologia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

4
Angel Onate

Profesor Titular

Microbiología

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

4
Daniela Gutiérrez

Encargada de laboratorio Ingeniería sanitaria

Ingeniería

Universidad de Santiago de Chile

Santiago, Chile

3
Juan Salazar

Profesor Asociado

Instituto de Ciencias Biomédicas

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

3
Leandro Cadiz

Jefe Técnico

Patología Animal

Universidad de Chile

Santiago, Chile

2
Mauricio Arenas

Profesor Asistente

Bioinformática

UNIVERSIDAD DE TALCA

talca, Chile

2
Mauricio Farfán

Profesor Asociado

Departamento de Pediatria y Cirugia Infantil, Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile

Universidad de Chile

Providencia, Chile

1
Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jonathan Bronstein

Profesor clínico Asistente

Psiquiatría

Pontificia Universidad Católica

Santiago, Chile

1
Alfonso Miranda

1
Francisco Alvarez

Estudiante de Magister

Microbiología

Universidad de Concepción

Concepción , Chile

1
Marjorie De la Fuente

Académico investigador

Facultad de Medicina

Universidad Finis Terrae

Santiago , Chile

1
Jorge Fernandez

JEFE SUBDEPTO

BIOMEDICO NACIONAL Y DE REFERENCIA

INSTITUTO DE SALUD PUBLICA

santiago, Chile

1
JORGE QUENSE

Associate professor

Geohraphy

PONTIFICAL CATHOLIC UNIVERSITY OF CHILE, INSTITUTE OF GEOGRAPHY

Santiago, Chile

1
Rodrigo Quera

Gastroenterólogo

Gastroenterología

CLÍNICA LAS CONDES, SERVICIO DE GASTROENTEROLOGÍA

Santiago, Chile

1
Paz Orellana

Docente

Facultad de Ciencias de la

Universidad Autónoma de Chile

Santiago, Chile

1
Gisselle Barra

Profesional de laboratorio

ANDID

Instituto de Salud Publica

Santiago, Chile

1
Maria Valenzuela

VICEDECANA DE INVESTIGACION Y POSTGRADO

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
Juan Hormazabal

Jefe

Departamento Biomédico

Public Health Institute of Chile

Santiago, Chile

1
pamela araya

JEFE DE SECCIÓN

BIOMEDICO

INSTITUTO DE SALUD PUBLICA DE CHILE

SANTIAGO, Chile

1
Alvaro Muñoz

Profesor Titular

Universidad San Sebastián

Santiago, Chile

1
María Ulloa

Jefe de Laboratorio

Fundación COANIQUEM Avances Tecnológicos

Santiago, Chile

1
Luigi Devoto

PROFESOR TITULAR

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL,FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Yalda Lucero

Profesor Asistente

Programa de Microbiología y Micología; Departamento de Pediatría y Cirugía infantil;

DIVISIÓN NORTE, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE, DEPARTAMENTO DE PEDIATRÍA Y CIRUGÍA INFANTIL-HOSPITAL LUIS CALVO MACKENNA

Santiago, Chile