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David Rasko

Professor

University of Maryland

Baltimore, Estados Unidos

Microbial pathogen comparative genomics and transcriptomics focused on the identification and characterization of virulence factors and antimicrobial resistance.

Microbiology, UNIVERSITY OF ALBERTA. Canada, 2000
Microbiology, UNIVERSITY OF ALBERTA. Canada, 1995

Professor Full Time

UNIVERSITY OF MARYLAND - BALTIMORE

Baltimore, Estados Unidos

2008 - 2025
Professor Full Time

UNIVERSITY OF MARYLAND - BALTIMORE

Baltimore, Estados Unidos

2025 - At present

Professor Full Time

University of Maryland School of Dentistry

Baltimore, Estados Unidos

2025 - At present
Professor Full Time

University of Maryland School of Medicine

Baltimore, Estados Unidos

2008 - 2025


Characterization of the role of putative <i>Aeromonas caviae</i>-specific virulence factor, <i>flgB,</i> in virulence and host-pathogen interactions Hritzo, Bernadette A.; Michalski, Jane M.; Rasko, David A. Article ISI JOURNAL OF BACTERIOLOGY (2026)
Complete genomes of <i>Escherichia coli</i> isolates encoding the EatA autotransporter from pediatric sources Hritzo, Bernadette A.; Michalski Wilhelm, Jane M.; Rasko, David A. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2026)
Complete genomes of diverse <i>Escherichia coli</i> isolates lacking canonical virulence factors from pediatric sources Rasko, David A.; Hritzo, Bernadette A.; Michalski Wilhelm, Jane M. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2026)
Genomes of enteric pathogen isolates from polymicrobial infections in cases of pediatric diarrhea Hritzo, Bernadette A.; Michalski Wilhelm, Jane M.; Rasko, David A. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2026)
Characterization of <i>Shigella flexneri</i> serotype 6 strains from geographically diverse low- and middle-income countries Gabor, Caitlin E.; Chong, Charlotte E.; Lemme-Dumit, Jose M.; Hazen, Tracy H.; Baker, Kate S.; Kotloff, Karen L.; Kasumba, Irene N.; Tennant, Sharon M.; Badji, Henry; Hossain, M. Jahangir; et al. Article ISI MBIO (2025)
Complete genomes of hybrid <i>Escherichia coli</i> isolates containing virulence factors from enterotoxigenic and enteropathogenic pathovars Hritzo, Bernadette A.; Michalski, Jane M.; Sikorski, Michael J.; Rasko, David A. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2025)
Draft genome sequences of evolutionary distant <i>Yersinia</i> species representatives Brady, Amanda; Garrison, Taylor M.; Ernst, Robert K.; Rasko, David A.; Lawrenz, Matthew B. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2025)
Draft genomes of <i>Aeromonas</i> species isolated from humans Michalski, Jane M.; Hritzo, Bernadette A.; Jones, Jennifer A.; Permala-Booth, Jasnehta; Tennant, Sharon M.; Rasko, David A. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2025)
EPEC autotransporter adhesin (Eaa): a novel adhesin identified in atypical enteropathogenic <i>Escherichia coli</i> Orsi, Henrique; de Lira, Daiany R. P.; Castilho, Ivana G.; de Souza, Guilherme F. R.; Onur, Tugce; Chura-Chambi, Rosa M.; Abe, Cecilia M.; Carvalho, Eneas; dos Santos, Luis F.; Rasko, David A.; et al. Article ISI FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2025)
The TyphiNET data visualisation dashboard: unlocking <i>Salmonella</i> Typhi genomics data to support public health Dyson, Zoe A.; Cerdeira, Louise; Sharma, Vandana; Carey, Megan E.; Holt, Kathryn E.; Typhoid Genomics Consortium Article ISI GENOME MEDICINE (2025)
Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent <i>Salmonella</i> Typhi Ingle, Danielle J.; Hawkey, Jane; Hunt, Martin; Iqbal, Zamin; Keane, Jacqueline A.; Afolayan, Ayorinde O.; Ahmed, Niyaz; Andleeb, Saadia; Ashton, Philip M.; Bogoch, Isaac I.; et al. Article ISI GENOME MEDICINE (2025)
<i>Pseudomonas aeruginosa</i> Lipid A Structural Variants Induce Altered Immune Responses Hofstaedter, Casey E.; O'Keefe, Ian P.; Met, Charles M.; Wu, Ling; Vanderwoude, Jelly; Shin, Sunny; Diggle, Stephen P.; Riquelme, Sebastian A.; Rasko, David A.; Doi, Yohei; et al. Article ISI AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2024)
Characterization of <i>Pseudomonas aeruginosa</i> from subjects with diffuse panbronchiolitis Met, Charles M.; Hofstaedter, Casey E.; O'Keefe, Ian P.; Yang, Hyojik; Moustafa, Dina A.; Sherman, Matthew E.; Doi, Yohei; Rasko, David A.; Sweet, Charles R.; Goldberg, Joanna B.; et al. Article ISI MICROBIOLOGY SPECTRUM (2024)
Deciphering transcript architectural complexity in bacteria and archaea Mattick, John S. A.; Bromley, Robin E.; Watson, Kaylee J.; Adkins, Ricky S.; Holt, Christopher I.; Lebov, Jarrett F.; Sparklin, Benjamin C.; Tyson, Tyonna S.; Rasko, David A.; Hotopp, Julie C. Dunning Article ISI MBIO (2024)
Detecting Residual Chronic Salmonella Typhi Carriers on the Road to Typhoid Elimination in Santiago, Chile, 2017-2019 Lagos; R.M.; Sikorski; M.J.; HormazÃ¡bal; J.C.; FernÃ¢ndez; A.; Duarte; S.; Pasetti; M.F.; Rasko; D.A.; Higginson; E.; Nkeze; J.; Kasumba; et al. Article ISI SCOPUS Journal of Infectious Diseases (2024)
Divergent <i>Pseudomonas aeruginosa</i> LpxO enzymes perform site-specific lipid A 2-hydroxylation Hofstaedter, Casey E.; Chandler, Courtney E.; Met, Charles M.; Gillespie, Joseph J.; Harro, Janette M.; Goodlett, David R.; Rasko, David A.; Ernst, Robert K.; Rahme, Laurence Article ISI MBIO (2024)
Factors associated with patient-to-healthcare personnel (HCP) and HCP-to-subsequent patient transmission of methicillin-resistant <i>Staphylococcus aureus</i> Adediran, Timileyin Y.; Robinson, Gwen L.; Johnson, J. Kristie; Liang, Yuanyuan; Bejo, Sarah; Leekha, Surbhi; Rasko, David A.; Stine, O. Colin; Harris, Anthony D.; Thom, Kerri A. Article ISI INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY (2024)
Gastrointestinal signals in supplemented media reveal a role in adherence for the <i>Shigella flexneri sap</i> autotransporter gene Leon, Yrvin; Honigsberg, Raphael; Rasko, David A.; Faherty, Christina S. Article ISI GUT MICROBES (2024)
Phenotypic diversity of type III secretion system activity in enteropathogenic<i> Escherichia</i><i> coli</i> clinical isolates Contreras, Carmen A.; Hazen, Tracy H.; Guadarrama, Carmen; Cervantes-Rivera, Ramon; Ochoa, Theresa J.; Vinuesa, Pablo; Rasko, David A.; Puente, Jose L. Article ISI JOURNAL OF MEDICAL MICROBIOLOGY (2024)
Clinical and Bacterial Characteristics Associated with Glove and Gown Contamination by Carbapenem-Resistant Klebsiella pneumoniae in the Health Care Setting Hazen, Tracy H. H.; Adediran, Timileyin; Hitchcock, Stephanie; O'Hara, Lyndsay M. M.; Pineles, Lisa; Michalski, Jane M. M.; Johnson, J. Kristie; Nguyen, M. Hong; Calfee, David P. P.; Miller, Loren G. G.; et al. Article ISI MICROBIOLOGY SPECTRUM (2023)
Genomic and Functional Characterization of Longitudinal Pseudomonas aeruginosa Isolates from Young Patients with Cystic Fibrosis Chandler, Courtney E.; Hofstaedter, Casey E.; Hazen, Tracy H.; Rasko, David A.; Ernst, Robert K. Article ISI MICROBIOLOGY SPECTRUM (2023)
Genomic diversity of non-diarrheagenic fecal <i>Escherichia coli</i> from children in sub-Saharan Africa and south Asia and their relatedness to diarrheagenic <i>E. coli</i> Hazen, Tracy H.; Michalski, Jane M.; Tennant, Sharon M.; Rasko, David A. Article ISI NATURE COMMUNICATIONS (2023)
Genomic, transcriptomic, and phenotypic differences among archetype <i>Shigella flexneri</i> strains of serotypes 2a, 3a, and 6 Gabor, Caitlin E.; Hazen, Tracy H.; Delaine-Elias, BreOnna C.; Rasko, David A.; Barry, Eileen M. Article ISI MSPHERE (2023)
Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes Carey, Megan E.; Ingle, Danielle J.; Amir, Afreenish; Aworh, Mabel K.; Chattaway, Marie Anne; Chew, Ka Lip; Feasey, Nicholas A.; Howden, Benjamin P.; Keddy, Karen; Parry, Christopher M.; et al. Article SCOPUS eLife (2023)
Molecular concordance of methicillin-resistant <i>Staphylococcus aureus</i> isolates from healthcare workers and patients Adediran, Timileyin Y.; Hitchcock, Stephanie; Johnson, J. Kristie; Stine, O. Colin; Leekha, Surbhi; Thom, Kerri A.; Liang, Yuanyuan; Rasko, David A.; Harris, Anthony D. Article ISI INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY (2023)
The role of the minor colonization factor CS14 in adherence to intestinal cell models by geographically diverse ETEC isolates Smith, Emily M.; Papadimas, Antonia; Gabor, Caitlin; Cooney, Ceanna; Wu, Tao; Rasko, David; Barry, Eileen M. Article ISI MSPHERE (2023)
Characterization of Adherent-Invasive Escherichia coli (AIEC) Outer Membrane Proteins Provides Potential Molecular Markers to Screen Putative AIEC Strains Pardo, Mirka; Araya, Daniela; Farfan, Mauricio J.; Rasko, Dave A.; Vidal, Roberto M. Article ISI SCOPUS International Journal of Molecular Sciences (2022)
Comparative Genomics Identifies Features Associated with Methicillin-Resistant Staphylococcus aureus (MRSA) Transmission in Hospital Settings Adedrian, Timileyin; Hitchcock, Stephanie; O'Hara, Lyndsay M.; Michalski, Jane M.; Johnson, J. Kristie; Calfee, David P.; Miller, Loren G.; Hazen, Tracy H.; Harris, Anthony D.; Rasko, David A. Article ISI MSPHERE (2022)
Dynamics of the Gut Microbiome in <i>Shigella</i>-Infected Children during the First Two Years of Life Ndungo, Esther; Holm, Johanna B.; Gama, Syze; Buchwald, Andrea G.; Tennant, Sharon M.; Laufer, Miriam K.; Pasetti, Marcela F.; Rasko, David A. Article ISI MSYSTEMS (2022)
Genome sequencing of <i>Pseudomonas aeruginosa</i> strain M2 illuminates traits of an opportunistic pathogen of burn wounds Verhoeve, Victoria, I; Brammer, Jerod A.; Driscoll, Timothy P.; Kambouris, Adrienne R.; Rasko, David A.; Cross, Alan S.; Gillespie, Joseph J. Article ISI G3-GENES GENOMES GENETICS (2022)
Pathogenomic analyses of <i>Shigella</i> isolates inform factors limiting shigellosis prevention and control across LMICs Bengtsson, Rebecca J.; Simpkin, Adam J.; Pulford, Caisey V.; Low, Ross; Rasko, David A.; Rigden, Daniel J.; Hall, Neil; Barry, Eileen M.; Tennant, Sharon M.; Baker, Kate S. Article ISI NATURE MICROBIOLOGY (2022)
Persistence of Rare <i>Salmonella</i> Typhi Genotypes Susceptible to First-Line Antibiotics in the Remote Islands of Samoa Sikorski, Michael J.; Hazen, Tracy H.; Desai, Sachin N.; Nimarota-Brown, Susana; Tupua, Siaosi; Sialeipata, Michelle; Rambocus, Savitra; Ingle, Danielle J.; Duchene, Sebastian; Ballard, Susan A.; et al. Article ISI MBIO (2022)
Spatial-temporal and phylogenetic analyses of epidemiologic data to help understand the modes of transmission of endemic typhoid fever in Samoa Sikorski, Michael J.; Ma, Jianguo; Hazen, Tracy H.; Desai, Sachin N.; Tupua, Siaosi; Nimarota-Brown, Susana; Sialeipata, Michelle; Rambocus, Savitra; Ballard, Susan A.; Valcanis, Mary; et al. Article ISI PLOS NEGLECTED TROPICAL DISEASES (2022)
Comparative Genomics of Atypical Enteropathogenic <i>Escherichia coli</i> from Kittens and Children Identifies Bacterial Factors Associated with Virulence in Kittens Watson, Victoria E.; Hazen, Tracy H.; Rasko, David A.; Jacob, Megan E.; Elfenbein, Johanna R.; Stauffer, Stephen H.; Gookin, Jody L. Article ISI INFECTION AND IMMUNITY (2021)
Comparison of long-read sequencing technologies in interrogating bacteria and fly genomes Tvedte, Eric S.; Gasser, Mark; Sparklin, Benjamin C.; Michalski, Jane; Hjelmen, Carl E.; Johnston, J. Spencer; Zhao, Xuechu; Bromley, Robin; Tallon, Luke J.; Sadzewicz, Lisa; et al. Article ISI G3-GENES GENOMES GENETICS (2021)
Contribution of Noncanonical Antigens to Virulence and Adaptive Immunity in Human Infection with Enterotoxigenic <i>E</i>. <i>coli</i> Kuhlmann, F. M.; Laine, R. O.; Afrin, S.; Nakajima, R.; Akhtar, M.; Vickers, T.; Parker, K.; Nizam, N. N.; Grigura, V; Goss, C. W.; et al. Article ISI INFECTION AND IMMUNITY (2021)
Draft Genome Sequences of Two Enteroinvasive <i>Escherichia coli</i> Strains Representative of Major Enteroinvasive <i>E</i>. <i>coli</i> Clades Sikorski, Michael J.; Hazen, Tracy H.; Vyas, Gopi; Michalski, Jane M.; Rasko, David A. Article ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2021)
Evaluation of a high-throughput, cost-effective Illumina library preparation kit Tvedte, Eric S.; Michalski, Jane; Cheng, Shaoji; Patkus, Rayanna S.; Tallon, Luke J.; Sadzewicz, Lisa; Bruno, Vincent M.; Silva, Joana C.; Rasko, David A.; Dunning Hotopp, Julie C. Article ISI SCIENTIFIC REPORTS (2021)
FADU: a Quantification Tool for Prokaryotic Transcriptomic Analyses Chung, Matthew; Adkins, Ricky S.; Mattick, John S. A.; Bradwell, Katie R.; Shetty, Amol C.; Sadzewicz, Lisa; Tallon, Luke J.; Fraser, Claire M.; Rasko, David A.; Mahurkar, Anup; et al. Article ISI MSYSTEMS (2021)
Risk factors for transmission of carbapenem-resistant Enterobacterales to healthcare personnel gloves and gowns in the USA O'Hara, L. M.; Nguyen, M. H.; Calfee, D. P.; Miller, L. G.; Pineles, L.; Magder, L. S.; Johnson, J. K.; Morgan, D. J.; Rasko, D. A.; Harris, A. D.; et al. Article ISI JOURNAL OF HOSPITAL INFECTION (2021)
Use of Antimicrobial-Coated Catheters in Preventing Catheter-Associated Urinary Tract Infections and Bacteriuria: A Meta-Analysis for Clinicians Vopni, Rachel; Voice, Alesia; de Riese, Cornelia S.; Garza, John; de Riese, Werner T. Article ISI UROLOGY PRACTICE (2021)
Chaperone-Usher Pili Loci of Colonization Factor-Negative Human Enterotoxigenic Escherichia coli Torres, Alexia; Cádiz, Leandro; Valdés, Raul; Mansilla, Aquiles; Hernández, Daniela; Caro, Benjamin; Levine, Myron M.; Rasko, David A.; Hill, Christopher M.; Pop, Mihai; et al. Article ISI SCOPUS FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)


Comparative Genomics Identifies Features Associated with Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) Transmission in Hospital Settings (vol 7, e00116-22, 2022) Adediran, Timileyin; Hitchcock, Stephanie; O'Hara, Lyndsay M.; Michalski, Jane M.; Johnson, J. Kristie; Calfee, David P.; Miller, Loren G.; Hazen, Tracy H.; Harris, Anthony D.; Rasko, David A. Correction ISI MSPHERE (2022)
Examination of 388 <i>Staphylococcus aureus</i> Isolates from Intensive Care Unit Patients (vol 8, e01246-19, 2019) Adediran, Timileyin; Hitchcock, Stephanie; O'Hara, Lyndsay M.; Michalski, Jane M.; Johnson, J. Kristie; Calfee, David P.; Miller, Loren G.; Hazen, Tracy H.; Rasko, David A.; Harris, Anthony D. Correction ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2022)
Examination of <i>Staphylococcus aureus</i> Isolates from the Gloves and Gowns of Intensive Care Unit Health Care Workers (vol 9, e00691-20, 2020) Adediran, Timileyin; Hitchcock, Stephanie; O'Hara, Lyndsay M.; Michalski, Jane M.; Johnson, J. Kristie; Calfee, David P.; Miller, Loren G.; Hazen, Tracy H.; Harris, Anthony D.; Rasko, David A. Correction ISI MICROBIOLOGY RESOURCE ANNOUNCEMENTS (2022)


Best practices on the differential expression analysis of multi-species RNA-seq Chung, Matthew; Bruno, Vincent M.; Rasko, David A.; Cuomo, Christina A.; Munoz, Jose F.; Livny, Jonathan; Shetty, Amol C.; Mahurkar, Anup; Dunning Hotopp, Julie C. Review ISI GENOME BIOLOGY (2021)