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Washington Nicolas

Postdoctoral Researcher

Fundación Ciencia y Vida

Santiago, Chile

Peripheral Neuropathies; Neuronal Cell Biology; Neurophisiology; Axonal degeneration; Synaptic proteostasis; Integrated Stress Response; Synapse degeneration; Alzheimer; Peripheral neuropathies; Neuropathic Pain; Necroptosis; Neuronal energetics

Doctorado en Ciencias Biológicas mención Ciencias Fisiológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile
Neurophysiology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2018

Profesor adjunto Part Time

UNIVERSIDAD MAYOR

Ciencias

Santiago, Chile

2017 - 2017

Ayudante del curso Bio361e

Pontificia Universidad Catolica de Chile

Chile

2009 - 2009
Asistente de Investigacion

Pontificia Universidad Catolica de Chile

Chile

2007 - 2010
Asistente de Investigacion

Pontificia Universidad Catolica de Chile

Chile

2011 - At present
Tesista de Postgrado (cotutoría)

Centro de Estudios Cientificos Valdivia

Chile

2013 - At present
Lecturer

MR Consultant

Chile

2014 - At present
Investigador Postdoctoral Full Time

Fundacion Ciencia y Vida

Santiago, Chile

2018 - At present
Profesor Adjunto Part Time

Universidad Mayor

Santiago, Chile

2017 - Not Available
Docente Part Time

Universidad San Sebastian

Santiago, Chile

2019 - At present


Metformin protects from oxaliplatin induced peripheral neuropathy in rats Article Neurobiology of Pain (2020)
Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice Kline, Rachel A.; Dissanayake, Kosala N.; Martinez, Nicolas W.; Ahl, Alexander; Mole, Alannah J.; Court, Felipe A.; Ribchester, Richard R.; Murray, Lyndsay M. Article ISI SCOPUS NEUROBIOLOGY OF DISEASE (2019)
Axonal Degeneration Is Mediated by Necroptosis Activation Saquel C.; Barrientos S.A.; MartÃnez N.W. Article ISI SCOPUS JOURNAL OF NEUROSCIENCE (2019)
Calcium Release from Intra-Axonal Endoplasmic Reticulum Leads to Axon Degeneration through Mitochondrial Dysfunction Villegas R, Martinez NW, Lillo J, Pihan P, Hernandez D, Twiss JL, Court FA Article ISI SCOPUS JOURNAL OF NEUROSCIENCE (2014)
Axonal Degeneration Is Mediated by the Mitochondrial Permeability Transition Pore Barrientos S.A.; Martinez, N.W.; Alvarez J.; Court, F. A.; Yoo S.; Zamorano S.; Hetz C. ; Twiss J.L. Article ISI SCOPUS Journal of Neuroscience (2011)


CALCIUM INCREASE IN THE AXOPLASM FROM INTRACELLULAR STORES IS THE FIRST EVENT LEADING TO MITOCHONDRIA DYSFUNCTION AND AXONAL DEGENERATION FONDECYT (3130610) Proyecto 2013-2015 Tesista
MECHANISMS INVOLVED IN THE AXONAL DEGENERATION PROGRAM=> ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION FONDECYT (1110987) Proyecto 2011-2015 Personal técnico y/o de apoyo
GLIA-TO-AXON TRANSFER OF RIBOSOMES=> PATHWAY AND REGULATORY MECHANISMS. FONDECYT (1070377) Proyecto 2007-2010 Tesista