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Pamela Yohana Sandoval Oporto

Postdoctoral Researcher

Centro de Estudios Científicos -CECs-

Valdivia, Chile

Toxicidad mitocondrial. Aplicación de nanosensores metabólicos como herramientas en plataformas de alto rendimiento. Identificación de RNA pequeños no codificantes que participan en la edición del genoma y sus implicaciones en el metabolismo celular.

PhD in Genetics, Texas A&M University. Estados Unidos, 2011
Licenciada en Bioquímica, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2001
Bioquímica, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2001

Lecturer of Beyond genetic inheritance: epigenetic gene regulation, chromatin structure and nuclear organization Part Time

UNIVERSITY OF BERN, Institute of Cell Biology

Faculty of Science

Berna, Suiza

2012 - 2014
Teaching Assistant of fundamental principles of genetics Part Time

Texas A&M University, Department of Biochemistry

College Station, Estados Unidos

2003 - 2004

POST-DOCTORAL Full Time

UNIVERSITY OF BERN, Institute of Cell Biology

Berna, Suiza

2011 - 2015
Graduate Research Assistant Full Time

Texas A&M University, Department of Molecular and Cellular Medicine, Texas A&M Health Science Center

College Station, Estados Unidos

2004 - 2011
Research Associate Full Time

Texas A&M University, Department of Biology

College Station, Estados Unidos

2001 - 2003
Asistente de investigación Full Time

Pontificia Universidad Católica de Chile, Departamento de Microbiología y Genética Molecular

Santiago, Chile

1999 - 2001
POST-DOCTORAL Full Time

Centro de Estudios Cientificos

Valdivia, Chile

2016 - At present

Co-supervisor, Thesis to obtain the degree of Master in Biological Sciences. Degree offered by the Universita'Degli Studi di Camerino-Italy to Ms. Gloria Silveri (2014-2015)
Co-supervisor, Thesis to obtain the degree of Master in Cell Biology. Degree offered by the University of Bern-Switzerland to Ms. Aditi Singh (2011-2013)


A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC Arce-Molina, Robinson; Cortes-Molina, Francisca; Sandoval, Pamela Y.; Galaz, Alex; Alegria, Karin; Schirmeier, Stefanie; Felipe Barros, L.; San Martin, Alejandro Article ISI SCOPUS ELIFE (2020)
Fluid Brain Glycolysis: Limits, Speed, Location, Moonlighting, and the Fates of Glycogen and Lactate Barros, L. Felipe; San Martin, Alejandro; Ruminot, Ivan; Sandoval, Pamela Y.; Baeza-Lehnert, Felipe; Arce-Molina, Robinson; Rauseo, Daniela; Contreras-Baeza, Yasna; Galaz, Alex; Valdivia, Sharin. Article ISI SCOPUS NEUROCHEMICAL RESEARCH (2020)
MitoToxy assay: A novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic Contreras-Baeza, Yasna; Ceballo, Sebastián; Arce-Molina, Robinson; Sandoval, Pamela Y.; Alegría, Karin; Barros, Luis Felipe.; San Martín, Alejandro; Deli, Mária A. Article ISI SCOPUS PLOS ONE (2019)
Monocarboxylate transporter 4 (MCT4) is a high affinity transporter capable of exporting lactate in high-lactate microenvironments Contreras-Baeza, Yasna; Sandoval, Pamela Y.; Alarcon, Romina; Galaz, Alex; Cortes-Molina, Francisca; Alegria, Karin; Baeza-Lehnert, Felipe; Arce-Molina, Robinson; Guequen, Anita; Flores, Carlos A.; San Martin, Alejandro; Felipe Barros, L. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Near-Critical GLUT1 and Neurodegeneration Barros, L. Felipe; San Martín, Alejandro; Ruminot, Ivan; Sandoval, Pamela Y.; Fernández-Moncada, Ignacio; Baeza-Lehnert, Felipe; Arce-Molina, Robinson; Contreras-Baeza, Yasna; Cortés-Molina, Francisca; GALAZ, ALEX; Alegría, Karin Article ISI SCOPUS JOURNAL OF NEUROSCIENCE RESEARCH (2017)
Two Sets of Piwi Proteins Are Involved in Distinct sRNA Pathways Leading to Elimination of Germline-Specific DNA Furrer, Dominique I.; Swart, Estienne C.; Kraft, Matthias F.; Sandoval, Pamela Y.; Nowacki, Mariusz Article CELL REPORTS (2017)
Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena Sandoval, Pamela Y.; Lee, Po-Hsuen; Meng, Xiangzhou; Kapler, Geoffrey M.; Loidl, Josef Article PLOS GENETICS (2015)
Functional Diversification of Dicer-like Proteins and Small RNAs Required for Genome Sculpting Sandoval, Pamela Y.; Swart, Estienne C.; Arambasic, Miroslav; Nowacki, Mariusz Article Developmental Cell (2014)
Genome-wide analysis of genetic and epigenetic control of programmed DNA deletion Swart, Estienne C.; Denby Wilkes, Cyril; Sandoval, Pamela Y.; Arambasic, Miroslav; Sperling, Linda; Nowacki, Mariusz Article NUCLEIC ACIDS RESEARCH (2014)
Paramecium tetraurelia chromatin assembly factor-1-like protein PtCAF-1 is involved in RNA-mediated control of DNA elimination Ignarski, M.; Singh, A.; Swart, E. C.; Arambasic, M.; Sandoval, P. Y.; Nowacki, M. Article NUCLEIC ACIDS RESEARCH (2014)
Pdsg1 and Pdsg2, Novel Proteins Involved in Developmental Genome Remodelling in Paramecium Arambasic, Miroslav; Sandoval, Pamela Y.; Hoehener, Cristina; Singh, Aditi; Swart, Estienne C.; Nowacki, Mariusz Article PubMed PLOS ONE (2014)
Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins Donti, Taraka R; Datta, Shibani; Sandoval, Pamela Y; Kapler, Geoffrey M Article THE EMBO JOURNAL (2009)
TIF1 Activates the Intra-S-Phase Checkpoint Response in the Diploid Micronucleus and Amitotic Polyploid Macronucleus of Tetrahymena Yakisich, J. S.; Sandoval, P. Y.; Morrison, T. L.; Kapler, G. M. Article PubMed MOLECULAR BIOLOGY OF THE CELL (2006)
High-Throughput Functional Analysis of the Synechococcus elongatus PCC 7942 Genome Holtman CK, Chen Y, Sandoval P, Gonzales A, Nalty MS, Thomas TL, Youderian P, Golden SS Article PubMed DNA RESEARCH (2005)
Transfer of RPS14 and RPL5 from the mitochondrion to the nucleus in grasses Sandoval, P; León G.; Gómez I.; Carmona, R.; Figueroa P.; Holuigue, L; Araya, A; JORDANA, X Article ISI SCOPUS GENE (2004)