Man

Pamela Cruz Espinoza

Investigadora Postdoctoral

Universidad Autónoma de Chile

Santiago, Chile

Líneas de Investigación


Oncología Veterinaria en animales de compañía y de vida silvestre. Cáncer mamario y cánceres transmisibles. Estudios del efecto de calreticulina de Trypanosoma cruzi sobre la inmunogenicidad de células tumorales.

Educación

  •  Médico Veterinario, UNIVERSIDAD DE CHILE. Chile, 2011
  •  Licenciada en Medicina Veterinaria, UNIVERSIDAD DE CHILE. Chile, 2008
  •  Biomedicina y Prevención de Enfermedades, UNIVERSIDAD DE CHILE. Chile, 2020

Experiencia Profesional

  •   Tesista de Pregrado Full Time

    Universidad de Chile

    Santiago, Chile

    2009 - 2011

  •   Técnico de Laboratorio Part Time

    Universidad de Chile

    Santiago, Chile

    2011 - 2012

  •   Médico Veterinario Part Time

    Centro de Especialidades Médico Veterinarias

    Santiago, Chile

    2013 - 2013

  •   Tesista de Postgrado Full Time

    Universidad de Chile

    Santiago, Chile

    2014 - At present

  •   Investigadora Asociada Part Time

    Universidad de Chile

    Santiago, Chile

    2020 - 2021


 

Article (8)

Hormonal Carcinogenesis in Canine Mammary Cancer: Molecular Mechanisms of Estradiol Involved in Malignant Progression
<i>In vitro</i> Treatment of a Murine Mammary Adenocarcinoma Cell Line with Recombinant <i>Trypanosoma cruzi</i> Calreticulin Promotes Immunogenicity and Phagocytosis
Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells
Simvastatin modulates beta-catenin/MDR1 expression on spheres derived from CF41.Mg canine mammary carcinoma cells
27-hydroxycholesterol and the expression of three estrogen-sensitive proteins in MCF7 cells
27-Hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype
Modulation of immune response during canine distemper virus infection: Therapeutic and vaccine development implications Modulación de la respuesta inmune durante la infección por virus distemper canino: Implicancias terapéuticas y en el desarrollo de vacunas
Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol

BookSection (1)

Companion animals as models for human mammary cancer research

ConferencePoster (4)

Transmissible cancers and the immunogenic role of Trypanosoma cruzi calreticulin
Transmissible Cancers and the Immunogenic Role of Trypanosoma cruzi Calreticulin: C1q Binding in Canine Transmissible Venereal Tumor Cells Mediated by TcCRT
Effects of 27-hydroxycholesterol on the expression of estrogen receptors (ERs) and MnSOD in mammary tumor cells
Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol, a novel SERM

Proyecto (2)

TRYPANOSOMA CRUZI CALRETICULIN, BY VIRTUE OF ITS ANTI-ANGIOGENIC PROPERTIES, INHIBITS TUMOR GROWTH IN EXPERIMENTAL MODELS
PROLIFERATION OF MAMMARY CELLS AFTER EXPOSURE TO 27-HYDROXYCHOLESTEROL, A NOVEL SELECTIVE MODULATOR OF ESTROGEN RECEPTORS (SERM).

Review (1)

Modulation of immune response during canine distemper virus infection: therapeutic and vaccine development implications
14
Pamela Cruz

Investigadora Postdoctoral

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

5
Cristian Torres

Profesor Asociado

Ciencias Clínicas

Universidad de Chile

Santiago, Chile

4
Cristian Torres

Profesor Asistente

Ciencias Clínicas

Universidad de Chile

Santiago, Chile

1
María Iturriaga

Profesor asistente

Pontificia Universidad Católica de Chile

Santiago, Chile