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Pamela Cruz Espinoza

Investigadora Postdoctoral

Universidad Autónoma de Chile

Santiago, Chile

Oncología Veterinaria en animales de compañía y de vida silvestre. Cáncer mamario y cánceres transmisibles. Estudios del efecto de calreticulina de Trypanosoma cruzi sobre la inmunogenicidad de células tumorales.

Médico Veterinario, UNIVERSIDAD DE CHILE. Chile, 2011
Licenciada en Medicina Veterinaria, UNIVERSIDAD DE CHILE. Chile, 2008
Biomedicina y Prevención de Enfermedades, UNIVERSIDAD DE CHILE. Chile, 2020

Tesista de Pregrado Full Time

Universidad de Chile

Santiago, Chile

2009 - 2011
Técnico de Laboratorio Part Time

Universidad de Chile

Santiago, Chile

2011 - 2012
Médico Veterinario Part Time

Centro de Especialidades Médico Veterinarias

Santiago, Chile

2013 - 2013
Tesista de Postgrado Full Time

Universidad de Chile

Santiago, Chile

2014 - At present
Investigadora Asociada Part Time

Universidad de Chile

Santiago, Chile

2020 - 2021


Hormonal Carcinogenesis in Canine Mammary Cancer: Molecular Mechanisms of Estradiol Involved in Malignant Progression Torres, Cristian G.; Iturriaga, Maria P.; Cruz, Pamela Article ISI Animals (2021)
<i>In vitro</i> Treatment of a Murine Mammary Adenocarcinoma Cell Line with Recombinant <i>Trypanosoma cruzi</i> Calreticulin Promotes Immunogenicity and Phagocytosis Sosoniuk-Roche, Eduardo; Cruz, Pamela; Maldonado, Ismael; Duaso, Leonora; Pesce, Barbara; Michalak, Marek; Valck, Carolina; Ferreira, Arturo Article ISI MOLECULAR IMMUNOLOGY (2020)
Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells Cruz P.; Sosoniuk-Roche E.; Maldonado I.; Torres C.G.; Ferreira A. Article ISI SCOPUS IMMUNOBIOLOGY (2019)
Simvastatin modulates beta-catenin/MDR1 expression on spheres derived from CF41.Mg canine mammary carcinoma cells Cruz, P.; Reyes, F.; Torres, C. G. Article ISI SCOPUS POLISH JOURNAL OF VETERINARY SCIENCES (2018)
27-hydroxycholesterol and the expression of three estrogen-sensitive proteins in MCF7 cells Cruz, P.; Epunan M.J.; Ramirez, M. E.; Torres, C. G.; Valladares L.E.; Sierralta W.D. Article ISI SCOPUS ONCOLOGY REPORTS (2012)
27-Hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype Torres, CG; Ramirez, ME; Cruz, P.; Epunan, MJ; Valladares, LE; Sierralta WD Article ISI SCOPUS ONCOLOGY REPORTS (2011)
Modulation of immune response during canine distemper virus infection: Therapeutic and vaccine development implications Modulación de la respuesta inmune durante la infección por virus distemper canino: Implicancias terapéuticas y en el desarrollo de vacunas Cespedes P.F.; Cruz, P.; Navarro C.O. Article SCOPUS ARCHIVOS DE MEDICINA VETERINARIA (2010)
Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol Cruz, P.; Torres C.; Ramirez, ME; Epunan, MJ; Valladares, LE; Sierralta WD Article ISI SCOPUS Experimental and Therapeutic Medicine (2010)


Companion animals as models for human mammary cancer research Cruz, Pamela; Piccaluga, Pier Paolo BookSection (2023)


Transmissible cancers and the immunogenic role of Trypanosoma cruzi calreticulin Cruz, Pamela; Torres, Cristian; Ferreira, Arturo ConferencePoster (2016)
Transmissible Cancers and the Immunogenic Role of Trypanosoma cruzi Calreticulin: C1q Binding in Canine Transmissible Venereal Tumor Cells Mediated by TcCRT Cruz, Pamela; Torres, Cristian; Ferreira, Arturo ConferencePoster (2016)
Effects of 27-hydroxycholesterol on the expression of estrogen receptors (ERs) and MnSOD in mammary tumor cells Cruz, Pamela; Ramírez, María E.; Epuñán, María J.; Torres, Cristian G.; Valladares, Luis E.; Sierralta, Walter D. ConferencePoster (2011)
Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol, a novel SERM Cruz, Pamela; Epuñán, María J.; Torres, Cristian G.; Ramírez, María E.; Valladares, Luis E.; Sierralta, Walter D. ConferencePoster (2010)


TRYPANOSOMA CRUZI CALRETICULIN, BY VIRTUE OF ITS ANTI-ANGIOGENIC PROPERTIES, INHIBITS TUMOR GROWTH IN EXPERIMENTAL MODELS FONDECYT (1130099) Proyecto 2013-2017 Tesista
PROLIFERATION OF MAMMARY CELLS AFTER EXPOSURE TO 27-HYDROXYCHOLESTEROL, A NOVEL SELECTIVE MODULATOR OF ESTROGEN RECEPTORS (SERM). FONDECYT (1090057) Proyecto 2009-2012 Tesista


Modulation of immune response during canine distemper virus infection: therapeutic and vaccine development implications Cespedes, PF; Cruz, P.; Navarro, CO Review ISI SCIELO ARCHIVOS DE MEDICINA VETERINARIA (2010)

Pamela Cruz

Investigadora Postdoctoral

Instituto de Ciencias Biomédicas

Universidad Autónoma de Chile

Santiago, Chile

Cristian Torres

Profesor Asociado

Ciencias Clínicas

Universidad de Chile

Santiago, Chile

Cristian Torres

Profesor Asistente

Ciencias Clínicas

Universidad de Chile

Santiago, Chile

María Iturriaga

Profesor asistente

Pontificia Universidad Católica de Chile

Santiago, Chile

Pamela Cruz Espinoza

Líneas de Investigación

Educación

Médico Veterinario, UNIVERSIDAD DE CHILE. Chile, 2011

Licenciada en Medicina Veterinaria, UNIVERSIDAD DE CHILE. Chile, 2008

Biomedicina y Prevención de Enfermedades, UNIVERSIDAD DE CHILE. Chile, 2020

Experiencia Profesional

Tesista de Pregrado Full Time

Técnico de Laboratorio Part Time

Médico Veterinario Part Time

Tesista de Postgrado Full Time

Investigadora Asociada Part Time

Article (8)

Hormonal Carcinogenesis in Canine Mammary Cancer: Molecular Mechanisms of Estradiol Involved in Malignant Progression

<i>In vitro</i> Treatment of a Murine Mammary Adenocarcinoma Cell Line with Recombinant <i>Trypanosoma cruzi</i> Calreticulin Promotes Immunogenicity and Phagocytosis

Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells

Simvastatin modulates beta-catenin/MDR1 expression on spheres derived from CF41.Mg canine mammary carcinoma cells

27-hydroxycholesterol and the expression of three estrogen-sensitive proteins in MCF7 cells

27-Hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype

Modulation of immune response during canine distemper virus infection: Therapeutic and vaccine development implications Modulación de la respuesta inmune durante la infección por virus distemper canino: Implicancias terapéuticas y en el desarrollo de vacunas

Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol

BookSection (1)

Companion animals as models for human mammary cancer research

ConferencePoster (4)

Transmissible cancers and the immunogenic role of Trypanosoma cruzi calreticulin

Transmissible Cancers and the Immunogenic Role of Trypanosoma cruzi Calreticulin: C1q Binding in Canine Transmissible Venereal Tumor Cells Mediated by TcCRT

Effects of 27-hydroxycholesterol on the expression of estrogen receptors (ERs) and MnSOD in mammary tumor cells

Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol, a novel SERM

Proyecto (2)

TRYPANOSOMA CRUZI CALRETICULIN, BY VIRTUE OF ITS ANTI-ANGIOGENIC PROPERTIES, INHIBITS TUMOR GROWTH IN EXPERIMENTAL MODELS

PROLIFERATION OF MAMMARY CELLS AFTER EXPOSURE TO 27-HYDROXYCHOLESTEROL, A NOVEL SELECTIVE MODULATOR OF ESTROGEN RECEPTORS (SERM).

Review (1)

Modulation of immune response during canine distemper virus infection: therapeutic and vaccine development implications

Pamela Cruz

Cristian Torres

Cristian Torres

María Iturriaga