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Patricia Virginia Diaz Amor

Inmunopatogenia del asma bronquial grave y respuesta inmune a virus respiratorios.

Medico-Cirujano, UNIVERSIDAD DE CHILE. Chile, 1968
Immunopathology , UNIVERSITY OF EDINBURGH. ESCOCIA, 1979
Enfermedades Respiratoria, UNIVERSIDAD DE CHILE. Chile, 1987

Profesora Asociada Part Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

1980 - At present

Profesora Asociada Part Time

Universidad de Chile

Santiago, Chile

1980 - At present


Changes in symptoms of asthma and rhinitis by sensitization status over ten years in a cohort of young Chilean adults. Garcia-Larsen, Vanessa; Potts, James F; Del Giacco, Stefano; Bustos, Patricia; Diaz, Patricia V; Amigo, Hugo; Oyarzun, Manuel; Rona, Roberto J Article BMC pulmonary medicine (2016)
Pro-Inflammatory Cytokines in Nasopharyngeal Aspirate From Hospitalized Children With Respiratory Syncytial Virus Infection With or Without Rhinovirus Bronchiolitis, and Use of the Cytokines as Predictors of Illness Severity Diaz, PV; Valdivia G, Gaggero; AA, Bono MR; Zepeda, G; Rivas M., Uasapud; P, Pinto; RA, Boza; ML, Guerrero J Article Medicine (United States) (2015)
Pro-Inflammatory Cytokines in Nasopharyngeal Aspirate From Hospitalized Children With Respiratory Syncytial Virus Infection With or Without Rhinovirus Bronchiolitis, and Use of the Cytokines as Predictors of Illness Severity Diaz PV; Valdivia G.; Zepeda, G; Rivas, M; Uasapud, P; Pinto, RA; Guerrero, J Article ISI SCOPUS Medicine (United States) (2015)
[Levels of inflammatory cytokines and plasma cortisol in respiratory syncytial virus bronchiolitis]. Díaz, Patricia V; Gaggero, Aldo A; Pinto, Ricardo A; Mamani, Rossana; Uasapud, Paola A; Bono, María Rosa Article Revista medica de Chile (2013)
Levels of inflammatory cytokines and plasma cortisol in respiratory syncytial virus bronchiolitis Diaz PV; Pinto, RA; Mamani, R Article ISI REVISTA MEDICA DE CHILE (2013)
Increased expression of the glucocorticoid receptor Î² in infants with RSV bronchiolitis. Diaz, Patricia V; Pinto, Ricardo A; Mamani, Rossana; Uasapud, Paola A; Bono, Maria R; Gaggero, Aldo A; Guerrero, Julia; Goecke, Annelise Article Pediatrics (2012)
Childhood environment and atopic conditions, with emphasis on asthma in a Chilean agricultural area Vargas C., Bustos P.; Diaz, PV; Amigo H., Rona Article JOURNAL OF ASTHMA (2008)
Childhood environment and atopic conditions, with emphasis on asthma in a Chilean agricultural area Vargas, C.; Bustos, P.; Diaz PV; Amigo, H; Rona, RJ Article ISI SCOPUS JOURNAL OF ASTHMA (2008)
Agreement between responses to a standardized asthma questionnaire and a questionnaire following a demonstration of asthma symptoms in adults Smeeton, NC; Rona, RJ; Oyarzún M.; Diaz PV Article ISI SCOPUS AMERICAN JOURNAL OF EPIDEMIOLOGY (2006)
Agreement between responses to a standardized asthma questionnaire and a questionnaire following a demonstration of asthma symptoms in adults. Smeeton, Nigel C; Rona, Roberto J; Oyarzun, Manuel; Diaz, Patricia V Article American journal of epidemiology (2006)
Safety and tolerability of inhaled budesonide in children in the Steroid Treatment As Regular Therapy in early asthma (START) trial Silverman, M; Sheffer, AL; Diaz PV; Lindberg, B Article ISI SCOPUS PEDIATRIC ALLERGY AND IMMUNOLOGY (2006)
Safety and tolerability of inhaled budesonide in children in the Steroid Treatment As Regular Therapy in early asthma (START) trial Silverman, M; Sheffer, AL; Diaz, PV; Lindberg, B Article PEDIATRIC ALLERGY AND IMMUNOLOGY (2006)
Safety and tolerability of inhaled budesonide in children in the Steroid Treatment As Regular Therapy in early asthma (START) trial. Silverman, Michael; Sheffer, Albert L; Díaz, Patricia V; Lindberg, Bengt Article Pediatric allergy and immunology => official publication of the European Society of Pediatric Allergy and Immunology (2006)
T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol Pinto, RA; Arredondo, SM; Bono MR, Gaggero; AA, Diaz Article Pediatrics (2006)
T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol Pinto, RA; Arredondo, SM; Diaz PV Article ISI SCOPUS PEDIATRICS (2006)
T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol. Pinto, Ricardo A; Arredondo, Sonia M; Bono, Maria R; Gaggero, Aldo A; Díaz, Patricia V Article Pediatrics (2006)
Long-term safety of once-daily budesonide in patients with early-onset mild persistent asthma: results of the Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) study Sheffer, AL; Silverman, M; Woolcock, AJ; Diaz PV; Lindberg, B; Lindmark, B Article ISI ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2005)
Long-term safety of once-daily budesonide in patients with early-onset mild persistent asthma=> results of the Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) study Sheffer, AL; Silverman, M; Woolcock, AJ; Diaz, PV; Lindberg, B; Lindmark, B Article ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2005)
Long-term safety of once-daily budesonide in patients with early-onset mild persistent asthma=> results of the Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) study. Sheffer, Albert L; Silverman, Mike; Woolcock, Ann J; Díaz, Patricia V; Lindberg, Bengt; Lindmark, Bertil Article Annals of allergy, asthma & immunology => official publication of the American College of Allergy, Asthma, & Immunology (2005)
Outcome of pregnancy in a randomized controlled study of patients with asthma exposed to budesonide Silverman, M; Sheffer, A; Diaz, PV; Lindmark, B; Radner, F; Broddene, M; de Verdier, MG; Pedersen, S; Pauwels, RA Article ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2005)
Outcome of pregnancy in a randomized controlled study of patients with asthma exposed to budesonide Silverman, M; Sheffer, A; Diaz PV; Lindmark, B; Radner, F; Broddene, M; de Verdier, MG; Pedersen S.; Pauwels, RA Article ISI SCOPUS ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2005)
Outcome of pregnancy in a randomized controlled study of patients with asthma exposed to budesonide. Silverman, Michael; Sheffer, Albert; Diaz, Patricia V; Lindmark, Bertil; Radner, Finn; Broddene, Maria; de Verdier, Maria Gerhardsson; Pedersen, Søren; Pauwels, Romain A Article Annals of allergy, asthma & immunology => official publication of the American College of Allergy, Asthma, & Immunology (2005)
Prevalence of asthma, atopy and bronchial hyperresponsiveness and their interrelation in a semi-rural area of Chile. Mackenney, J; Oyarzun, M J; Diaz, P V; Bustos, R; Amigo, H; Rona, R J Article The international journal of tuberculosis and lung disease => the official journal of the International Union against Tuberculosis and Lung Disease (2005)
The early origins hypothesis with an emphasis on growth rate in the first year of life and asthma: a prospective study in Chile Rona, RJ; Smeeton, NC; Bustos, P.; Amigo, H; Diaz PV Article ISI SCOPUS THORAX (2005)
The early origins hypothesis with an emphasis on growth rate in the first year of life and asthma=> a prospective study in Chile Rona, RJ; Smeeton, NC; Bustos P., Amigo H.; Diaz, PV Article THORAX (2005)
The early origins hypothesis with an emphasis on growth rate in the first year of life and asthma=> a prospective study in Chile. Rona, R J; Smeeton, N C; Bustos, P; Amigo, H; Diaz, P V Article Thorax (2005)
Differential effects of respiratory syncytial virus and adenovirus on mononuclear cell cytokine responses. Díaz, P V; Calhoun, W J; Hinton, K L; Avendaño, L F; Gaggero, A; Simon, V; Arredondo, S M; Pinto, R; Díaz, A Article American journal of respiratory and critical care medicine (1999)
Respiratory syncytial virus infection in infants is associated with predominant Th-2-like response. Román, M; Calhoun, W J; Hinton, K L; Avendaño, L F; Simon, V; Escobar, A M; Gaggero, A; Díaz, P V Article American journal of respiratory and critical care medicine (1997)
Childhood environment and atopic conditions, with emphasis on asthma in a Chilean agricultural area. Vargas, Claudio; Bustos, Patricia; Diaz, Patricia V; Amigo, Hugo; Rona, Roberto J Article The Journal of asthma => official journal of the Association for the Care of Asthma (0)


Ten year changes in symptoms of asthma and rhinitis by sensitisation status in a cohort of young adults Garcia-Larsen, V; Potts, JF; Bustos, P.; Diaz PV; Amigo, H; Oyarzún M.; Rona, RJ Abstract ISI ALLERGY (2014)
Upregulation Of Glucocorticoids Beta Receptors In Severe Rsv Bronchiolitis In Infants Diaz PV; Mammani, R; Pinto, RA; Guerrero, J; Goecke, A Abstract ISI JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
Some Inflammatory Citokines in Nasopharyngheal Aspirates from Respiratory Syncytial Virus Infected Infants remain Increased Independantly from the Presence of the Virus Diaz PV; Pinto, RA; Goecke, A Abstract ISI JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2011)
CTLA-4+ and CD25+ T cells down regulation are associated to severe respiratory syncytial virus infection Diaz PV; Pinto, RA; Arredondo, SM; Bono, M. Abstract ISI JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Increased IFN-gamma and IL-10 and decreased IL-12 production by peripheral blood mononuclear cells from young children with asthma-like symptoms Diaz PV; Pinto, R; Arredondo, SM; Gaggero A. Abstract ISI JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2002)


INSENSITIVITY TO GLUCOCORTICOIDS ANTI-INFLAMMATORY EFFECT DURING SEVERE RESPIRATORY SYNCYTIAL VIRUS INFECTION MAY BE AN EARLY MARKER OF DEVELOPMENT OF RECURRENT WHEEZING AND ATOPY IN CHILDREN FONDECYT (1120411) Proyecto 2012-2016 Inv. Responsable
MECANISMO PATOGENICO DE LA SEVERIDAD DE LA INFECCION POR VIRUS RESPIRATORIO SINCICIAL=> UNA RESPUESTA INMUNE INNATA EXAGERADA O UN DESBALANCE DE LA RESPUESTA INMUNE CELULAR TIPO TH-1/TH-2 MEDIADAS POR EL CORTISOL ENDOGENO FONDECYT (1090261) Proyecto 2009-2012 Inv. Responsable
DAÑO PULMONAR INDUCIDO POR OZONO=> INTERACCION CON COBRE O CINC DEL MATERIAL PARTICULADO DEL AIRE Y SU EVENTUAL MODULACION INMUNOLOGICA Y/O ADAPTATIVA. FONDECYT (1061085) Proyecto 2006-2009 Coinvestigador(a)
PARVOVIRUS B19, UN PROBLEMA CLINICO EMERGENTE. ASPECTOS EPIDEMIOLOGICOS, VIROLOGICOS E INMUNOLOGICOS DE LA INFECCION. FONDECYT (1030478) Proyecto 2003-2006 Coinvestigador(a)
DETERMINACION DE MARCADORES INMUNOLOGICOS DE FACTORES DE RIESGO DE DESARROLLO DE ASMA BRONQUIAL EN EL NINO MENOR DE CINCO ANOS FONDECYT (1000640) Proyecto 2000-2003 Inv. Responsable
ROL DE LAS INFECCIONES VIRALES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICAL(VRS) Y ADENOVIRUS (ADV) EN LA INMUNOPATOGENIA DEL ASMA BRONQUIAL FONDECYT (1950647) Proyecto 1995-1998 Inv. Responsable
ENSAYOS TERAPEUTICOS EN ALVEOLITIS FOBROSANTES CRIPTOGENICA. CORRELACION CLINICA Y EXPERIMENTAL FONDECYT (1940260) Proyecto 1994-1997 Coinvestigador(a)
INTERRELACION EN VIVO E IN VITRO DEL VIRUS RESPIRATORIO SINCICIAL (VRS)Y ADENOVIRUS (ADV) CON CELULAS INMUNOCOMPETENTES DE LA VIA AEREA Y SANGRE PERIFERICA FONDECYT (1920932) Proyecto 1992-1995 Inv. Responsable
IMPACTO DEL CUIDADO EN SALA CUNA SOBRE LA PATOLOGIA RESPIRATORIA AGUDA EN EL MENOR DE 18 MESES DE EDAD FONDECYT (1911111) Proyecto 1991-1993 Coinvestigador(a)
RESPUESTA DE CELULAS INMUNOCOMPETENTES ANTE LA INFECCION IN VITRO E IN VIVO POR VIRUS RESPIRATORIO SINCICIAL (VRS). FONDECYT (1901079) Proyecto 1990-1991 Inv. Responsable
INFECCION POR VIRUS SINCICIAL RESPIRATORIO EN LACTANTES HOSPITALIZADOS FONDECYT (1880097) Proyecto 1988-1990 Coinvestigador(a)

Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

Aldo Gaggero

Académico. Profesor Asociado.

Virología

ICBM. FACULTAD DE MEDICINA. UNIVERSIDAD DE CHILE.

Santiago, Chile

Julia Guerrero

académico

Programa Disciplinario Fisiologia y Biofisica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Gonzalo Valdivia

Division Head, Full Professor

Medical School

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Guillermo Zepeda

Profesor Asistente

Pediatría y Cirugía Infantil, Campus Norte

Universidad de Chile

Santiago, Chile

PAOLA UASAPUD

Patricia Diaz

Mabel Rivas

Titular

Pediatria

Hospital

Santiago, Chile

Claudio Vargas

Urgencia 28 horas

Hospital de Urgencias Asistencia Pública

Santiago, Chile

Patricia Virginia Diaz Amor

Líneas de Investigación

Educación

Medico-Cirujano, UNIVERSIDAD DE CHILE. Chile, 1968

Immunopathology , UNIVERSITY OF EDINBURGH. ESCOCIA, 1979

Enfermedades Respiratoria, UNIVERSIDAD DE CHILE. Chile, 1987

Experiencia Académica

Profesora Asociada Part Time

Experiencia Profesional

Profesora Asociada Part Time

Article (29)

Abstract (5)

Proyecto (11)

INSENSITIVITY TO GLUCOCORTICOIDS ANTI-INFLAMMATORY EFFECT DURING SEVERE RESPIRATORY SYNCYTIAL VIRUS INFECTION MAY BE AN EARLY MARKER OF DEVELOPMENT OF RECURRENT WHEEZING AND ATOPY IN CHILDREN

MECANISMO PATOGENICO DE LA SEVERIDAD DE LA INFECCION POR VIRUS RESPIRATORIO SINCICIAL=> UNA RESPUESTA INMUNE INNATA EXAGERADA O UN DESBALANCE DE LA RESPUESTA INMUNE CELULAR TIPO TH-1/TH-2 MEDIADAS POR EL CORTISOL ENDOGENO

DAÑO PULMONAR INDUCIDO POR OZONO=> INTERACCION CON COBRE O CINC DEL MATERIAL PARTICULADO DEL AIRE Y SU EVENTUAL MODULACION INMUNOLOGICA Y/O ADAPTATIVA.

PARVOVIRUS B19, UN PROBLEMA CLINICO EMERGENTE. ASPECTOS EPIDEMIOLOGICOS, VIROLOGICOS E INMUNOLOGICOS DE LA INFECCION.

DETERMINACION DE MARCADORES INMUNOLOGICOS DE FACTORES DE RIESGO DE DESARROLLO DE ASMA BRONQUIAL EN EL NINO MENOR DE CINCO ANOS

ROL DE LAS INFECCIONES VIRALES RESPIRATORIAS POR VIRUS RESPIRATORIO SINCICAL(VRS) Y ADENOVIRUS (ADV) EN LA INMUNOPATOGENIA DEL ASMA BRONQUIAL

ENSAYOS TERAPEUTICOS EN ALVEOLITIS FOBROSANTES CRIPTOGENICA. CORRELACION CLINICA Y EXPERIMENTAL

INTERRELACION EN VIVO E IN VITRO DEL VIRUS RESPIRATORIO SINCICIAL (VRS)Y ADENOVIRUS (ADV) CON CELULAS INMUNOCOMPETENTES DE LA VIA AEREA Y SANGRE PERIFERICA

IMPACTO DEL CUIDADO EN SALA CUNA SOBRE LA PATOLOGIA RESPIRATORIA AGUDA EN EL MENOR DE 18 MESES DE EDAD

RESPUESTA DE CELULAS INMUNOCOMPETENTES ANTE LA INFECCION IN VITRO E IN VIVO POR VIRUS RESPIRATORIO SINCICIAL (VRS).

INFECCION POR VIRUS SINCICIAL RESPIRATORIO EN LACTANTES HOSPITALIZADOS