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Ana Luz Quiroga Campano

Investigadora

Universidad de Chile

Santiago, Chile

Generación de valor estratégico de alto impacto para la industria biotecnológica chilena, mediante la optimización de bioprocesos: producción de vacunas veterinarias para la salmonicultura y cultivo de células humanas para medicina regenerativa

Bioengineering, UNIVERSIDAD DE CHILE. Chile, 2010
Chemical Engineering, UNIVERSIDAD DE CHILE. Chile, 2010
Chemical Engineering, UNIVERSIDAD DE CHILE. Chile, 2012
Chemical Engineering, IMPERIAL COLLEGE LONDON. Reino Unido, 2017

Investigadora Other

UNIVERSIDAD DE CHILE

Ingeniería

Chile

2017 - At present
Postdoctoral Fellow Full Time

GEORGIA INSTITUTE OF TECHNOLOGY

Bioengineering

Estados Unidos

2019 - 2021

Plant supervisor Full Time

Aguas Andinas

Santiago, Chile

2011 - 2012
Project engineer Full Time

Aguas Andinas

Sanitago, Chile

2012 - 2012
Senior scientist Full Time

AstraZeneca

Cambridge, Reino Unido

2022 - At present
Investigadora Part Time

Universidad de Chile

Chile

2017 - At present

Software : Statgraphics, gPROMS, SuperPro Design, MATLAB, MAPLE and AUTOCAD.
Programming languages : Java and Visual Basic (MS Office).
Laboratory techniques :Bacterial (E. coli) and mammalian cell culture (GS-NS0)
Batch and fed-batch operation in flasks and bioreactors (1-7 [L])
Microscopy, electrophoresis, HPLC (amino acid analysis and antibody quantification) and flow cytometry.


Energy-Based Culture Medium Design for Biomanufacturing Optimization: A Case Study in Monoclonal Antibody Production by GS-NS0 Cells Quiroga-Campano, Ana L.; Panoskaltsis, Nicki; Mantalaris, Athanasios Article Metabolic Engineering (2018)
Advanced model-based control strategies for the intensification of upstream and downstream processing in mAb production Papathanasiou, Maria M.; Quiroga-Campano, Ana L.; Steinebach, Fabian; Elviro, Montaña; Mantalaris, Athanasios; Pistikopoulos, Efstratios N. Article Biotechnology Progress (2017)
Experimental Validation of the Predictions of a Mathematical Model for Protein Purification and Tag Selection Shene C.; Quiroga, A; Salazar, O.; Salgado J.C. Article ISI SCOPUS Separation Science and Technology (Philadelphia) (2010)


A Predictive Model for Energy Metabolism and ATP Balance in Mammalian Cells: Towards the Energy-Based Optimization of mAb Production Quiroga-Campano, A; Papathanasiou, M.; Pistikopoulos, E.; Mantalaris, A. ConferencePaper (2016)
Development of advanced computational tools for the intensification of monoclonal antibody production Papathanasiou, M.; Quiroga-Campano, A; Mantalaris, A.; Pistikopoulos, E. ConferencePaper (2016)


Application of mechanistic preclinical PK/PD/efficacy modeling to support combination strategy for AZD9750, a novel oral androgen receptor degrader (PROTAC) Ana Quiroga; Pablo Morentin Gutierrez; Antonio Ramos-Montoya; Chrysiis Michaloglou; Nuria Galeano-Dalmau; Claire Crafter; Aaron Smith; Jamie Scott; Michael Niedbala ConferencePoster (2026)
AZD4241, an orally bioavailable ERα PROTAC, degrades wild-type and mutant ERα and delivers anti-tumour activity in preclinical breast cancer models Mandy Lawson; Natalie Cureton; Lynet Nyoni; Sophie D’Arcy; Lydia Parkinson; Ana Quiroga; Pablo Morentin Gutierrez; Ji Li; Hana Baakza; Thomas Hayhow; Claire Crafter; Lucy Ireland; Gemma Hardman Fowler; Georgia M. Simmons; Lakjaya Buluwela; Simak Ali; Neil ConferencePoster (2026)
Preclinical mechanistic PK/PD/Efficacy modeling for AZD4241, a novel oral estrogen receptor (ER) degrader (PROTAC), to support dose selection during early clinical development Ana Quiroga; Pablo Morentin Gutierrez; Lynet Nyoni; Natalie Cureton; Mandy Lawson; Aaron Smith; Thomas Hayhow; Neil Gibson ConferencePoster (2026)
The combination of the AR PROTAC AZD9750 and AKT inhibitor capivasertib delivers improved efficacy over monotherapy in prostate cancer Antonio Ramos-Montoya; Chrysiis Michaloglou; Nuria Galeano-Dalmau; Ana Quiroga; Michael Niedbala; Claire Crafter ConferencePoster (2026)
AZD9750, a novel androgen receptor proteolysis targeting chimera (AR-PROTAC) for the treatment of prostate cancer Claire Crafter, Antonio Ramos-Montoya, Chrysiis Michaloglou, Ziyanda Shologu, Nuria Galeano-Dalmau, Gemma Hardman Fowler, Ana Quiroga, Pablo Morentin-Gutierrez, Andy Pike, Laura Evans, James S. Scott, Michael Niedbala ConferencePoster (2025)
Celia: a Model Based Platform for Media and Feeding Strategy Design for Improved Process Metrics Gerdtzen, Z.P., Paredes, I., Canales, A., Pizarro, F., Herrera, B., Prat, I., Molina, T., Quiroga-Campano A., Salgado, J.C ConferencePoster (2025)
Preclinical mechanistic PK/PD-efficacy modeling for AZD9750, a novel oral androgen receptor degrader (PROTAC), to support dose selection during early clinical development Pablo Morentin Gutierrez; Ana Quiroga Campano; Antonio Ramos Montoya; Claire Crafter; Chrysiis Michaloglou; Aaron Smith; Nuria Galeano Dalmau; Jamie Scott; Michael Niedbala ConferencePoster (2025)
Validation of the CELIA Platform: Design and Optimization of Culture Media and Feeding Strategies for Mammalian Cell-Based Biomanufacturing Processes Gerdtzen, Z.P., Paredes, I., Canales, A., Pizarro, F., Herrera, B., Prat, I., Molina, T., Quiroga-Campano A., Salgado, J.C ConferencePoster (2024)
Validation of the Model-based Cell Culture Media Design Platform “CELIA” for Biomass and Product Optimization in a Bioreactor Setting Gerdtzen, Z.P., Paredes, I., Villanueva, A., Narvaez, D., Morales, D., Carvajal, B., Quiroga-Campano A., Salgado, J.C. ConferencePoster (2023)
Development of a model-based cell culture media design platform for biomass and product optimization: current results and future perspective Gerdtzen, Z.P., Villanueva, A., Narvaez, D., Morales, D., Carvajal, B., Quiroga-Campano A., Salgado, J.C ConferencePoster (2022)
Incremento de biomasa en procesos de manufactura de biofármacos en Chile mediante estrategias de alimentación, diseño y optimización de medios de cultivo con la Plataforma CELIA Gerdtzen, Z.P., Villanueva, A., Narvaez, D., Quiroga-Campano A., Sánchez, F., Morales, D., Carvajal, B., Véliz, F., Flores, G., Pohlhammer, K., Salgado, J.C ConferencePoster (2022)
Cell composition determination of industrially relevant cell lines for a media design platform Villanueva, A., Narvaez, D., Quiroga-Campano A., Mantalaris, A., Gerdtzen Z.P. ConferencePoster (2021)
Bioprocess Optimizer: Culture media optimization platform for manufacturing bio-products Villanueva, A. A., Narva?ez. D., Olivares, J. M., Salgado, J.C., Quiroga-Campano, A. L., Gerdtzen, Z.P ConferencePoster (2019)
Quantification methodology of cellular compounds as input of a novel platform for cell culture media design Narva?ez. D., Villanueva, A. A., Quiroga-Campano, A. L., Gerdtzen, Z.P ConferencePoster (2019)
Personalized and optimized low-dose and intensive chemotherapy treatments for patients with Acute Myeloid Leukemia (AML) Quiroga, A, Foster, M, Enfield, L, Kostoglou, M, Georgiadis, M, Mantalaris, A, Panoskaltsis, N ConferencePoster (2018)
Dynamic optimization of the production of monoclonal antibodies in semi-batch operation Kappatou, C, Mhamdi, A, Quiroga, A, Mantalaris, A, Mitsos, A. ConferencePoster (2017)


Validación de plataforma CELIA: diseño y optimización de medios de cultivo y estrategias de alimentación para bioproceso Gerdtzen, Ziomara Patricia; Salgado, Jose Cristian Proyecto (2022)
Plataforma para el diseño de medios de cultivo: optimización de la manufactura de bio-productos Gerdtzen, Ziomara Patricia; Salgado, Jose Cristian Proyecto (2018)