Mathematical modelling, model-based optimization and control of biological system for manufacturing of bio-products, specialized in bacterial (E. coli / recombinan proteins) and mammalian cell lines (GS-NS0 / antibodies)

Software : Statgraphics, gPROMS, SuperPro Design, MATLAB, MAPLE and AUTOCAD.
Programming languages : Java and Visual Basic (MS Office).
Laboratory techniques :Bacterial (E. coli) and mammalian cell culture (GS-NS0)
Batch and fed-batch operation in flasks and bioreactors (1-7 [L])
Microscopy, electrophoresis, HPLC (amino acid analysis and antibody quantification) and flow cytometry.

Conferences

American Society of Hematology, ASH Annual Meeting (Atlanta, GA, USA), 8th-12th December, 2017
Precision Chemotherapy for Patients with Acute Myeloid Leukemia using the ?ichemo Prediction and Optimization Tool”. Poster Presentation

European Symposium on Computer-Aided Process Engineering (Barcelona, Spain). 1st-5th October, 2017
Kappatou, C., Quiroga-Campano, A., Mantalaris, A. “Dynamic optimization of the production of monoclonal antibodies in semi-batch operation”. Oral presentation.

AIChE Annual Meeting (San Francisco, CA, USA). 13th-18th November, 2016
Quiroga-Campano, A., Papathanasiou, M., Mantalaris, A., Pistikopoulos, E. “Energy-based medium design for mammalian cell fed-batch cultures”. Oral presentation.

European Symposium on Computer-Aided Process Engineering (Portorož, Slovenia). 12th-15th June, 2016
Quiroga-Campano, A., Papathanasiou, M., Mantalaris, A., Pistikopoulos, E. “A predictive model for energy metabolism and ATP balance in mammalian cells: Towards the energy-based optimization of mAb production”. Oral presentation.

Cell Culture (London, UK). 2nd-4th February, 2016
Quiroga-Campano, A., Papathanasiou, M., Mantalaris, A., Pistikopoulos, E. “A predictive model for energy metabolism in mammalian cells”. Oral presentation.

AIChE Annual Meeting (Salt Lake City, UT, USA). 8th-13th November, 2015
Papathanasiou, M., Quiroga-Campano, A., Mantalaris, A., Pistikopoulos, E. “Advanced control strategies towards the intensification of monoclonal antibody production”. Oral presentation.

Integrated Continuous Biomanufacturing II, (San Francisco, CA, USA). 1st–5th November, 2015
Papathanasiou, M., Quiroga-Campano, A., Mantalaris, A., Pistikopoulos, E. “Advanced computational tools to enhance continuous monoclonal antibody production”. Poster Presentation