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José Cristian Salgado Herrera

Associate Professor

UNIVERSIDAD DE CHILE

Santiago, Chile

Mathematical modeling, Molecular Modeling, Process Control, Systems Biology, Computational Biology, Automatic Modeling

Chemical Engineering and Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2005
Chemical Engineer, UNIVERSIDAD DE CHILE. Chile, 2002

Associate Professor Full Time

UNIVERSIDAD DE CHILE

Faculty of Physical and Mathematical Sciences

Santiago, Chile

2007 - At present

Associate Professor Full Time

University of Chile

Santiago, Chile

2007 - At present

Mejor docente de pregrado

UNIVERSIDAD DE CHILE

Chile, 2012

Distincio?n de la Universidad de Chile a los mejores docentes de pregrado.


Calcium is a noncompetitive inhibitor of DMT1 on the intestinal iron absorption process: empirical evidence and mathematical modeling analysis Aguirre, Pabla; Gerdtzen, Ziomara P.; Salgado, J. Cristian Article ISI AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2022)
Novel Symbiotic Genome-Scale Model Reveals Wolbachia's Arboviral Pathogen Blocking Mechanism in Aedes aegypti Gerdtzen, Ziomara P.; Salgado, J. Cristian Article mBio (2021)
Understanding the Phenomenon of Copper Ions Release from Copper-Modified TFC Membranes: A Mathematical and Experimental Methodology Using Shrinking Core Model Quezada, Rodrigo; Estay, Humberto. Article NANOMATERIALS (2020)
A systems biology approach for studying Wolbachia metabolism reveals points of interaction with its host in the context of arboviral infection Jimenez, Natalia E.; Gerdtzen, Ziomara P.; Salgado, J. Cristian Article ISI SCOPUS PLOS NEGLECTED TROPICAL DISEASES (2019)
Mathematical modeling of the relocation of the divalent metal transporter DMT1 in the intestinal iron absorption process Cegarra, Layimar; Colins, Andrea; Gerdtzen, Ziomara P.; Salgado, J. Cristian Article ISI SCOPUS PLOS ONE (2019)
Mathematical Modeling of Intestinal Iron Absorption Using Genetic Programming Colins A, Gerdtzen ZP, Nuñez MT, Salgado JC. Article ISI SCOPUS PLOS ONE (2017)
Sustainability indicators for the assessment of eco-industrial parks: classification and criteria for selection Valenzuela-Venegas, Guillermo; Salgado, J. Cristian; Díaz-Alvarado, Felipe Article JOURNAL OF CLEANER PRODUCTION (2016)
Iron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells Esparza, Andrs; Gerdtzen, Ziomara P.; Olivera-Nappa, Alvaro; Salgado, J. Cristian; Nez, Marco T. Article ISI SCOPUS American Journal of Physiology - Cell Physiology (2015)
Molecular dynamics simulation of halogen bonding mimics experimental data for cathepsin L inhibition Celis-Barros, C; Saavedra-Rivas L.; Salgado, J. C.; Cassels, B.K.; Zapata-Torres, G Article ISI SCOPUS JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2015)
Revealing Monoamine Oxidase B Catalytic Mechanisms by Means of the Quantum Chemical Cluster Approach Zapata-Torres, G; Fierro A.; Barriga-Gonzalez, G; Salgado JC; Celis-Barros, C Article Journal of Chemical Information and Modeling (2015)
Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from TIRAP Salgado, J. C.; Zapata-Torres, G; Gerdtzen, Z.P.; Gonzalez, M. J.; Hermoso M.A. Article ISI SCOPUS Biotechnology and Bioprocess Engineering (2012)
Influence of Protonation on Substrate and Inhibitor Interactions at the Active Site of Human Monoamine Oxidase-A Zapata-Torres, G; Fierro, A.; Miranda-Rojas, S; Guajardo, C.; Saez-Briones, P; Salgado, J. C.; Celis-Barros, C Article ISI SCOPUS JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
Design and simulation of a controller system for metabolic shift regulation in mammalian cells. Baeza, Damián; Gerdtzen, Ziomara P; Salgado, Cristian J Article BMC proceedings (2011)
Experimental Validation of the Predictions of a Mathematical Model for Protein Purification and Tag Selection Shene C.; Quiroga, A; Salazar, O; Salgado JC Article ISI SCOPUS Separation Science and Technology (Philadelphia) (2010)
Experimental Validation of the Predictions of a Mathematical Model for Protein Purification and Tag Selection Lienqueo, ME; Shene, C; Quiroga A.; Salazar, O; Salgado, JC; Asenjo, JA Article SEPARATION SCIENCE AND TECHNOLOGY (2010)
Mathematical modeling of the dynamic storage of iron in ferritin Salgado JC; Olivera-Nappa, A.; Tapia, V; Theil EC; Conca, C Article ISI SCOPUS BMC Systems Biology (2010)
Computer-aided design to select optimal polypeptide tags to assist the purification of recombinant proteins Lienqueo, ME; Salgado, JC; Giaverini O.; Asenjo, JA Article SEPARATION AND PURIFICATION TECHNOLOGY (2009)
Computer-aided design to select optimal polypeptide tags to assist the purification of recombinant proteins Salgado JC; Giaverini, O Article ISI SCOPUS SEPARATION AND PURIFICATION TECHNOLOGY (2009)
Modeling heterocyst pattern formation in cyanobacteria Salgado JC; Osses A.; Rapaport, I; Andrews, BA Article ISI SCOPUS BMC Bioinformatics (2009)
Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition Salgado, JC; Andrews, BA; Ortuzar, MF; Asenjo, JA Article JOURNAL OF CHROMATOGRAPHY A (2008)
New approaches for predicting protein retention time in hydrophobic interaction chromatography Lienqueo, ME; Mahn, A; Navarro, G; Salgado, JC; Perez-Acle T.; Rapaport, I; Asenjo, JA Article JOURNAL OF MOLECULAR RECOGNITION (2006)
Predicting the behaviour of proteins in hydrophobic interaction chromatography 1: Using the hydrophobic imbalance (HI) to describe their surface amino acid distribution Salgado, JC; Rapaport, I; Asenjo, JA Article JOURNAL OF CHROMATOGRAPHY A (2006)
Predicting the behaviour of proteins in hydrophobic interaction chromatography 2. Using a statistical description of their surface amino acid distribution Salgado, JC; Rapaport, I; Asenjo, JA Article JOURNAL OF CHROMATOGRAPHY A (2006)
Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition? Salgado, JC; Rapaport, I; Asenjo, JA Article JOURNAL OF CHROMATOGRAPHY A (2005)
Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition Salgado, JC; Rapaport, I; Asenjo, JA Article JOURNAL OF CHROMATOGRAPHY A (2005)
Effects of natural flavones and flavonols on the kinase activity of Cdk5. Zapata-Torres, Gerald; Opazo, Felipe; Salgado, Cristián; Muñoz, Juan Pablo; Krautwurst, Hans; Mascayano, Carolina; Sepúlveda-Boza, Silvia; Maccioni, Ricardo B; Cassels, Bruce K Article Journal of natural products (2004)
An Expert System for selection of Protein Purification Processes: Experimental Validation M.E. Lienqueo, J.C. Salgado, and J.A. Asenjo Article Journal of Chemical Technology & Biotechnology (1999)


A systemic model for the receptor complex NRC/MASC based on its inferred interproteic network Campos, J. A.; Gerdtzen, Z.P.; Salgado, J. C. ConferencePaper SCOPUS AIChE Annual Meeting, Conference Proceedings (2011)
Design and simulation of a controller system for metabolic shift regulation in mammalian cells Baeza D.; Gerdtzen, Z.P.; Salgado, J. C. ConferencePaper SCOPUS AIChE Annual Meeting, Conference Proceedings (2011)
Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides Salgado, J. C.; Gerdtzen, Z.P.; Hermoso M.A. ConferencePaper SCOPUS AIChE Annual Meeting, Conference Proceedings (2011)
A Novel Mathematical Model for the Study of Electrochemical Nucleation of Metals on Foreign Substrates from the Analysis of Potentiostatic Current Transients Vargas, T.; Colet, M; Salgado JC ConferencePaper ISI SCOPUS ECS Transactions (2010)


Design and implementation of software platform and mathematical models to design and optimize sustainable continuous membrane cascade processes to purify commercially valuable polyphenolic fractions from different plant matrices Salgado, J. Cristian Proyecto (2020)
Manufacture and Characterization of Electrochemical Photo Cells for the Production of Solar Fuels Colet, Melanie; Salgado, J. Cristian Proyecto (2018)
New applications of copper nanoparticles from mining products on emerging technologies for Desalination Process and Energy production PIA (ACM 170003) Proyecto 2018-2020 Investigador(a)
Platform for the design of culture media : optimization of the manufacture of bio-products Gerdtzen, Ziomara P.; Salgado, J. Cristian Proyecto (2018)
MOSTICAW - MOdeling the Spread and (opTImal) Control of Arboviroses by Wolbachia Salgado, J. Cristian Proyecto (2016)
Simulator of Physical Mechanical Properties in Corrugated Cardboard Gracia, Francisco; Salgado, J. Cristian Proyecto (2016)
CeBiB, Centre for Biotechnology and Bioengineering Basal founding of Scientific and Technological Centers of Excellence, Conicyt (FB0001) Proyecto 2014-2019 Investigador(a)
Researcher for Basal founding of Scientific and Technological Centers of Excellence for the creation of the “Centre for Biotechnology and Bioengineering Asenjo, Juan.; Salgado, J. Cristian Proyecto (2014)
A Systems Biology Approach for Studying and Understanding Cellular Processes Involved in the Regulation of Intestinal Iron Absorption Salgado, J. Cristian Proyecto (2013)
A SYSTEMS BIOLOGY APPROACH FOR STUDYING AND UNDERSTANDING CELLULAR PROCESSES INVOLVED IN THE REGULATION OF INTESTINAL IRON ABSORPTION FONDECYT (1130317) Proyecto 2013-2017 Inv. Responsable
Molecular docking study of PEGylated proteins for the analysis of their behavior on ion exchange (IEX) and hydrophobic interaction (HIC) chromatography Salgado, J. Cristian Proyecto (2013)
SEARCHING FOR POSSIBLE DEPROTONATION SITES FOR SUBSTRATES AND INHIBITORS OF HUMAN MAO-A FONDECYT (1120280) Proyecto 2012-2016 Coinvestigador(a)
Searching for possible deprotonation sites for substrates and inhibitors of human MAO-A Zapata, Gerald A.; Salgado, J. Cristian Proyecto (2012)
Mathematical modeling of the interaction between cell-penetrating TIR BB loop decoy peptides (BBPs) and toll-like receptor 4 and 2 (TLR4 and TLR2) Salgado, J. Cristian Proyecto (2008)
MATHEMATICAL MODELING OF THE INTERACTION BETWEEN CELL-PENETRATING TIR BB LOOP DECOY PEPTIDES (BBPS) AND TOLL-LIKE RECEPTOR 4 AND 2 (TLR4 AND TLR2) FONDECYT (11080016) Proyecto 2008-2011 Inv. Responsable
Institute for Cell Dynamics and Biotechnology=> A Centre for Systems Biology MIDEPLAN (P-05-001- F) Proyecto 2007-2011 Investigador(a)
Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using their three dimensional structure or their amino acid composition Salgado, J. Cristian Proyecto (2007)
PREDICTION OF THE PARTITIONING BEHAVIOUR OF PROTEINS IN AQUEOUS TWO-´ASE SUSTEMS USING THEIR THREE DIMENSIONAL STRUCTURE OR THEIR AMINO ACID COMPOSITION FONDECYT (3070031) Proyecto 2007-2008 Inv. Responsable
Institute for Cell Dynamics and Biotechnology: A Centre for Systems Biology Salgado, J. Cristian Proyecto (2006)


Mathematical Modeling of Protein Chromatograms Lienqueo M.E.; MAHN, A; Salgado, J. C.; Shene C. Review ISI SCOPUS Chemical Engineering and Technology (2012)
Methods of calculating protein hydrophobicity and their application in developing correlations to predict hydrophobic interaction chromatography retention MAHN, A; Salgado JC Review ISI SCOPUS Journal of Chromatography A (2009)
Current insights on protein behaviour in hydrophobic interaction chromatography MAHN, A; Salgado JC Review ISI JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2007)

Tomás Vargas

Profesor Asociado

Ingeniería Química, Biotecnología y materiales

UNIVERSIDAD DE CHILE (UCH), FACULTAD CS.FISICAS Y MATEMATICAS , DPTO INGENIERIA QUIMICA

Santiago, Chile

Carolina Shene

TITULAR PROFESSOR

CHEMICAL ENGINEERING

UNIVERSIDAD DE LA FRONTERA

TEMUCO, Chile

Maria Lienqueo

FULL PROFESSOR

OF CHEMICAL AND BIOTECHNOLOGY ENGINEERING

UNIVERSIDAD DE CHILE

Santiago, Chile

Maria Salazar

Profesora Asociada

Ingeniería Química Biotecnología y Materiales

UNIVERSIDAD DE CHILE, FAC. DE CIENCIAS FÍSICAS Y MATEMATICAS DEPTO. INGENIERÍA QUÍMICA

Santiago, Chile

Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

Marcela Hermoso

Full Professor

School of Medicine

UNIVERSIDAD DE CHILE

Santiago, Chile

Gerald Zapata

Profesor Asociado

Química Inorgánica y Analítica

Universidad de Chile

Santiago, Chile

Ziomara Gerdtzen

Profesora Asociada

Departamento de Ingeniería Química, Biotecnología y Materiales

Universidad de Chile

Santiago, Chile

Ivan Rapaport

Full Professor

Mathematical Engineering

Universidad de Chile

Santiago, Chile

ANDREA MAHN

Profesor Titular

Ingeniería Química

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

José Salgado

Associate Professor

Chemical Engineering, Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

Carlos Conca

CO-FOUNDER ASSOCIATE RESEARCHER

CENTER FOR MATHEMATICAL MODELING

UNIVERSIDAD DE CHILE

Santiago, Chile

Bruce Cassels

Profesor Titular

Departamento de Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE QUÍMICA

Santiago, Chile

Axel Osses

Profesor Titular

Departamento de Ingeniería Matemática

Universidad de Chile

Santiago, Chile

Sebastián Miranda

Profesor Asistente

Departamento de Ciencias Químicas

UNIVERSIDAD NACIONAL ANDRES BELLO

Santiago, Chile

Angelica Fierro

Associate

Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Alvaro Olivera

Principal Investigator and Assistant Professor

Chemical Engineering, Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

Barbara Andrews

FULL PROFESSOR

CHEMICAL ENGINEERING AND BIOTECHNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Juan Asenjo

Professor

CHEMICAL AND BIOTECHNOLOGY ENGINEERING

University of Chile

SANTIAGO, Chile

Melanie Colet

Profesora Asistente

Ingeniería Química, Biotecnología y Materiales

Universidad de Chile

Santiago, Chile

Natalia Jimenez

Profesora Asistente

Departamento de Ingeniería Biológica y Médica, Departamento de Ingeniería Química y Bioprocesos

Pontificia Universidad Católica de Chile

Santiago, Chile

Ana Quiroga

Senior scientist

Early oncology

AstraZeneca

Cambridge, Reino Unido

Andrea Colins

Postdoctorado

Neurociencias

Universidad de Chile

Santiago, Chile

José Cristian Salgado Herrera

Líneas de Investigación

Educación

Chemical Engineering and Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2005

Chemical Engineer, UNIVERSIDAD DE CHILE. Chile, 2002

Experiencia Académica

Associate Professor Full Time

Experiencia Profesional

Associate Professor Full Time

Premios y Distinciones

Mejor docente de pregrado

Article (27)

ConferencePaper (4)

Proyecto (19)

New applications of copper nanoparticles from mining products on emerging technologies for Desalination Process and Energy production

CeBiB, Centre for Biotechnology and Bioengineering

A SYSTEMS BIOLOGY APPROACH FOR STUDYING AND UNDERSTANDING CELLULAR PROCESSES INVOLVED IN THE REGULATION OF INTESTINAL IRON ABSORPTION

SEARCHING FOR POSSIBLE DEPROTONATION SITES FOR SUBSTRATES AND INHIBITORS OF HUMAN MAO-A

MATHEMATICAL MODELING OF THE INTERACTION BETWEEN CELL-PENETRATING TIR BB LOOP DECOY PEPTIDES (BBPS) AND TOLL-LIKE RECEPTOR 4 AND 2 (TLR4 AND TLR2)

Institute for Cell Dynamics and Biotechnology=> A Centre for Systems Biology

PREDICTION OF THE PARTITIONING BEHAVIOUR OF PROTEINS IN AQUEOUS TWO-´ASE SUSTEMS USING THEIR THREE DIMENSIONAL STRUCTURE OR THEIR AMINO ACID COMPOSITION

Review (3)