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Nicolas Rodrigo Crisosto King

Profesor Asistente

Universidad de Chile

Santiago, Chile

Fisiopatología del Síndrome de Ovario Poliquístico. Marcadores reproductivos y metabólicos en hijas de mujeres SOP Efecto de la testosterona sobre la producción de citoquinas proinflamatorias en tejido adiposo visceral de mujeres en edad reproductiva

Doctor en Ciencias Medicas, UNIVERSIDAD DE CHILE. Chile, 2010
Medico, UNIVERSIDAD DE CHILE. Chile, 2004
Medicina Interna, UNIVERSIDAD DE CHILE. Chile, 2010
Endocrinologia, UNIVERSIDAD DE CHILE. Chile, 2013
Medicina Basada en la Evidencia, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2013

PROFESOR ASISTENTE Full Time

UNIVERSIDAD DE CHILE

MEDICINA

SANTIAGO, Chile

2010 - At present

Residente UCI Part Time

Hospital San Juan de Dios

Santiago, Chile

2008 - 2014
Profesor Asistente Full Time

Universidad de Chile

Chile

2010 - At present
Endocrinólogo Part Time

Clínica Bicentenario

Chile

2013 - 2016
Endocrinologo Part Time

Clínica Las Condes

Chile

2016 - At present
Presidente Comité Científico Other

Sociedad Chilena de Endocrinologia y Diabetes

Chile

2019 - At present

Young Investigator Award

Androgen Excess and PCOS Society

Estados Unidos, 2006

Premio al Mejor Investigador Joven en el Congreso Anual de la Androgen Excess Society
Azziz Baumgartner Young Investigator Award

Androgen Excess and PCOS Society

Chile, 2008

Mejor Investigador Joven en Congreso anual de la Androgen Excess Society


Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis Gunning M.N.; Petermann T.S.; Crisosto N.; Van Rijn B.B.; De Wilde M.A.; Christ J.P.; Uiterwaal C.S.P.M.; De Jager W.; Eijkemans M.J.C.; Kunselman A.R.; Legro R.S.; Fauser B.C.J.M. Article ISI SCOPUS HUMAN REPRODUCTION UPDATE (2020)
Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis. Gunning MN; Sir Petermann T; Crisosto, N; van Rijn BB; de Wilde MA; Christ JP; Uiterwaal CSPM; de Jager W; Eijkemans MJC; Kunselman AR; Legro RS; Fauser BCJM Article Hum Reprod Update (2020)
DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS Echiburu, Barbara; Milagro, Fermin; Crisosto, Nicolas; Perez-Bravo, Francisco; Flores, Cristian; Arpon, Ana; Salas-Perez, Francisca; Recabarren, Sergio E.; Sir-Petermann, Teresa; Maliqueo, Manuel Article ISI EPIGENETICS (2020)
Higher luteinizing hormone levels associated with antimullerian hormone in postmenarchal daughters of women with polycystic ovary syndrome Crisosto, N; de Guevara, AL; Echiburu, B; Maliqueo, M; Cavada, G; Codner, E; Paez, F; Sir-Petermann, T Article ISI SCOPUS FERTILITY AND STERILITY (2019)
Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome Risal, Sanjiv; Pei, Yu; Lu, Haojiang; Manti, Maria; Fornes, Romina; Pui, Han-Pin; Zhao, Zhiyi; Massart, Julie; Ohlsson, Claes; Lindgren, Eva; Crisosto, Nicolas; Maliqueo, Manuel; Echiburu, Barbara; de Guevara, Amanda Ladron; Sir-Petermann, Teresa; Larsson, Henrik; Rosenqvist, Mina A.; Cesta, Carolyn E.; Benrick, Anna; Deng, Qiaolin; Stener-Victorin, Elisabet Article ISI SCOPUS NATURE MEDICINE (2019)
Developmental Programming of the Female Neuroendocrine System by Steroids Abruzzese GA; Crisosto, N; De Grava Kempinas W; Sotomayor-Zárate R Article JOURNAL OF NEUROENDOCRINOLOGY (2018)
Developmental programming of the female neuroendocrine system by steroids Abruzzese, Giselle Adriana; Crisosto, Nicolás; De Grava Kempinas, Wilma; Sotomayor-Zárate, Ramón Article JOURNAL OF NEUROENDOCRINOLOGY (2018)
Enlarged adipocytes in subcutaneous adipose tissue associated to hyperandrogenism and visceral adipose tissue volume in women with polycystic ovary syndrome Echiburu, B; Perez-Bravo, F; Galgani, JE; Sandoval, D; Saldias, C; Crisosto, N; Maliqueo, M; Sir-Petermann, T Article Steroids (2018)
Obesity during pregnancy affects sex steroid concentrations depending on fetal gender Maliqueo M.; Cruz, G; Espina C; Contreras, I.; García M; Echiburu B; Crisosto, N Article INTERNATIONAL JOURNAL OF OBESITY (2017)
Obesity during pregnancy affects sex steroid concentrations depending on fetal gender Maliqueo, Manuel; Cruz, Gonzalo; Espina, Carolina; Contreras, Isabella; García, Madian; Echiburú, Bárbara; Crisosto, Nicolas Article INTERNATIONAL JOURNAL OF OBESITY (2017)
Reproductive and Metabolic Features During Puberty in Sons of Women With Polycystic Ovary Syndrome Crisosto, N; Echiburú B; Maliqueo M.; Luchsinger M; Rojas P.; Recabarren S; Sir-Petermann T Article ENDOCRINE CONNECTIONS (2017)
Reproductive and metabolic features during puberty in sons of women with polycystic ovary syndrome Crisosto, N; Echiburu, B; Maliqueo, M; Luchsinger, M; Rojas, P; Recabarren, S; Sir-Petermann, T Article ENDOCRINE CONNECTIONS (2017)
Testosterone Increases CCL-2 Expression in Visceral Adipose Tissue From Obese Women of Reproductive Age Crisosto, N; Flores. C.; Maliqueo M.; Echiburú B; Vásquez J; Maluenda F; Sir-Petermann T Article MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)
Testosterone increases CCL-2 expression in visceral adipose tissue from obese women of reproductive age Crisosto, Nicolás; Flores, Cristián; Maliqueo, Manuel; Echiburú, Bárbara; Vásquez, Jaime; Maluenda, Fernando; Sir-Petermann, Teresa Article MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)
Metabolic Features Across The Female Life Span In Women With PCOS Sir-Petermann, Teresa; Echiburú, Barbara; Crisosto, Nicolás; Maliqueo, Manuel Article CURRENT PHARMACEUTICAL DESIGN (2016)
Metabolic profile in women with polycystic ovary syndrome across adult life Sir-Petermann, Teresa; Echiburú, Bárbara; Crisosto, Nicolás; Maliqueo Manuel, Perez-Bravo Francisco Article METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
Metabolic profile in women with polycystic ovary syndrome across adult life Echiburú B.; Crisosto, N; Maliqueo, M; Perez-Bravo, F; De Guevara A.L.; Hernández P; Cavada, G; Rivas, C; Clavel A.; Sir-Petermann, T Article ISI SCOPUS METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
Metabolic profile in women with polycystic ovary syndrome across adult life. Echiburú, Bárbara; Crisosto, Nicolás; Maliqueo, Manuel; Pérez-Bravo, Francisco; de Guevara, Amanda Ladron; Hernández, Paola; Cavada, Gabriel; Rivas, Catalina; Clavel, Andrés; Sir-Petermann, Teresa Article Metabolism: clinical and experimental (2016)
Sex Steroids Modulate Uterine-Placental Vasculature: Implications for Obstetrics and Neonatal Outcomes. Maliqueo, Manuel; Echiburú, Bárbara; Crisosto, Nicolás Article Frontiers in physiology (2016)
Sex Steroids Modulate Uterine-Placental Vasculature=> Implications for Obstetrics and Neonatal Outcomes Maliqueo, Manuel; Echiburú, Bárbara; Crisosto, Nicolás Article Frontiers in Physiology (2016)
[Effects of pregnancy and changes in body weight on polycystic ovary syndrome phenotypes according to the Rotterdam criteria]. Echiburú, Bárbara; Ladrón de Guevara, Amanda; Pereira, Cecilia; Pérez, Constanza; Michael, Pía; Crisosto, Nicolás; Sir-Petermann, Teresa Article Revista meÌ�dica de Chile (2014)
Effects of pregnancy and changes in body weight on polycystic ovary syndrome phenotypes according to the Rotterdam criteria Echiburú B.; de Guevara, AL; Pereira, C.; Pérez, C.; Michael P.; Crisosto, N; Sir Petermann T Article ISI REVISTA MEDICA DE CHILE (2014)
Metabolic profile of the different phenotypes of polycystic ovary syndrome in two Latin American populations de Guevara, AL; Fux-Otta, C; Crisosto, N; de Mereshian, PS; Echiburú B.; Iraci, G; Perez-Bravo, F; Sir Petermann T Article ISI SCOPUS FERTILITY AND STERILITY (2014)
Evaluation of ovarian function in 35-40-year-old women with polycystic ovary syndrome de Guevara, AL; Crisosto, N; Echiburú B.; Preisler, J; Vantman, N; Bollmann, J; Perez-Bravo, F; Sir Petermann T Article ISI SCOPUS European Journal of Obstetrics Gynecology and Reproductive Biology (2013)
Evaluation of ovarian function in 35-40-year-old women with polycystic ovary syndrome de Guevara, AL; Crisosto, N; Echiburu, B; Preisler, J; Vantman, N; Bollmann, J; Perez-Bravo, F; Sir-Petermann, T Article EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2013)
Placental steroidogenesis in pregnant women with polycystic ovary syndrome Maliqueo, M; Lara, HE; Sanchez, F; Echiburú B.; Crisosto, N; Sir Petermann T Article ISI SCOPUS European Journal of Obstetrics Gynecology and Reproductive Biology (2013)
CAG repeat polymorphism of androgen receptor gene and X-chromosome inactivation in daughters of women with polycystic ovary syndrome (PCOS): relationship with endocrine and metabolic parameters Echiburú B.; Perez-Bravo, F; Maliqueo, M; Ladron De Guevara A.; Gálvez C.; Crisosto, N; Sir Petermann T Article ISI SCOPUS Gynecological Endocrinology (2012)
Improvement of hyperandrogenism and hyperinsulinemia during pregnancy in women with polycystic ovary syndrome=> possible effect in the ovarian follicular mass of their daughters Crisosto, Nicolás; Echiburú, Bárbara; Maliqueo, Manuel; Pérez, Virginia; Ladrón de Guevara, Amanda; Preisler, Jessica; Sánchez, Fernando; Sir-Petermann, Teresa Article FERTILITY AND STERILITY (2012)
Relationship Between Anti-Mullerian Hormone (AMH) and Insulin Levels During Different Tanner Stages in Daughters of Women With Polycystic Ovary Syndrome Sir-Petermann, T; de Guevara, AL; Codner, E; Preisler, J; Crisosto, N; Echiburu, B; Maliqueo, M; Sanchez, F; Perez-Bravo, F; Cassorla, F Article REPRODUCTIVE SCIENCES (2012)
Relationship Between Anti-Mullerian Hormone (AMH) and Insulin Levels During Different Tanner Stages in Daughters of Women With Polycystic Ovary Syndrome Sir Petermann T; Guevara A.L.D.; Codner, E; Preisler, J; Crisosto, N; Echiburú B.; Maliqueo, M; Sanchez, F; Perez-Bravo, F; Cassorla F. Article ISI SCOPUS Reproductive Sciences (2012)
Relationship of serum adipocyte-derived proteins with insulin sensitivity and reproductive features in pre-pubertal and pubertal daughters of polycystic ovary syndrome women Maliqueo, M; Galgani, J. E.; Perez-Bravo, F; Echiburú B.; De Guevara A.L.; Crisosto, N; Sir Petermann T Article ISI SCOPUS European Journal of Obstetrics Gynecology and Reproductive Biology (2012)
Relationship of serum adipocyte-derived proteins with insulin sensitivity and reproductive features in pre-pubertal and pubertal daughters of polycystic ovary syndrome women. Maliqueo, Manuel; Galgani, José E; Pérez-Bravo, Francisco; Echiburú, Bárbara; de Guevara, Amanda Ladrón; Crisosto, Nicolás; Sir-Petermann, Teresa Article European journal of obstetrics, gynecology, and reproductive biology (2012)
Effects of Birth Weight on Anti-Mullerian Hormone Serum Concentrations in Infant Girls Sir Petermann T; Márquez L.; Cárcamo M.; Hitschfeld, C; Codner, E; Maliqueo, M; Echiburú B.; Aranda P.; Crisosto, N; Cassorla F. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (2010)
Adrenal Function during Childhood and Puberty in Daughters of Women with Polycystic Ovary Syndrome Maliqueo, M; Sir Petermann T; Pérez V; Echiburú B.; de Guevara, AL; Gálvez C.; Crisosto, N; Azziz R. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Metabolic and Reproductive Features before and during Puberty in Daughters of Women with Polycystic Ovary Syndrome Sir Petermann T; Codner, E; Pérez V; Echiburú B.; Maliqueo, M; de Guevara, AL; Preisler, J; Crisosto, N; Sanchez, F; Cassorla F.; Bhasin, S Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Metabolic parameters in cord blood of newborns of women with polycystic ovary syndrome Maliqueo, M; Echiburú B.; Crisosto, N; Amigo, P; Aranda P.; Sanchez, F; Sir Petermann T Article ISI SCOPUS FERTILITY AND STERILITY (2009)
Testosterone-induced downregulation of anti-Mullerian hormone expression in granulosa cells from small bovine follicles Crisosto, N; Sir Petermann T; Greiner M.; Maliqueo, M; Moreno, M.; Aedo, P; Lara, HE Article ISI SCOPUS ENDOCRINE (2009)
Polymorphism T -> C (-34 base pairs) of gene CYP17 promoter in women with polycystic ovary syndrome is associated with increased body weight and insulin resistance: a preliminary study Echiburú B.; Perez-Bravo, F; Maliqueo, M; Sanchez, F; Crisosto, N; Sir Petermann T Article ISI SCOPUS METABOLISM-CLINICAL AND EXPERIMENTAL (2008)
Anti-Mullerian hormone levels in peripubertal daughters of women with polycystic ovary syndrome Crisosto, N; Codner, E; Maliqueo, M; Echiburú B.; Sanchez, F; Cassorla F.; Sir Petermann T Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Early metabolic derangements in daughters of women with polycystic ovary syndrome Sir Petermann T; Maliqueo, M; Codner, E; Echiburú B.; Crisosto, N; Pérez V; Perez-Bravo, F; Cassorla F. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Gonadal function in low birth weight infants: A pilot study Sir Petermann T; Hitchsfeld, C; Codner, E; Maliqueo, M; Iñiguez G.; Echiburú B.; Sanchez, F; Crisosto, N; Cassorla F. Article ISI SCOPUS JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2007)
Serum adiponectin and lipid concentrations in pregnant women with polycystic ovary syndrome Sir Petermann T; Echiburú B.; Maliqueo, MM; Crisosto, N; Sanchez, F; Hitschfeld, C; Cárcamo M.; Amigo, P; Perez-Bravo, F Article ISI SCOPUS HUMAN REPRODUCTION (2007)
Increased anti-Mullerian hormone serum concentrations in prepubertal daughters of women with polycystic ovary syndrome Sir Petermann T; Codner, E; Maliqueo, M; Echiburú B.; Hitschfeld, C; Crisosto, N; Perez-Bravo, F; Recabarren SE; Cassorla F. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)


Dynamics of Anti-Mullerian Hormone (AMH) Serum Concentrations during the Peripubertal Period in PCOS Daughters. Sir Petermann T; Preisler, J; Echiburú B.; de Guevara, AL; Maliqueo, M; Crisosto, N; Pérez V; Sanchez, F Abstract ISI ENDOCRINE REVIEWS (2010)
Adrenal function during childhood and the onset of puberty in daughters of women with polycystic ovary syndrome (PCOS) Sir Petermann T; Pérez V; Maliqueo, M; Echiburú B.; Codner, E; Gálvez C.; Crisosto, N; Azziz R. Abstract ISI HORMONE RESEARCH (2008)


Altered TNF-alpha system in eutopic endometria with endometriosis compared to normal endometria Johnson, MC; Torres M.; Crisosto, N; Ponce C.; Bacallao, K; Gabler F.; Fuentes, A.; Boric, MA ConferencePaper ISI Human Reproduction (2005)


Caracterización de variantes genéticas asociadas a la respuesta clínica de metformina en mujeres chilenas con síndrome de ovario poliquístico (SOP) Sociedad Chilena de Endocrinología y Diabetes (SOCHED) (Proyecto SOCHED 2018-08) Proyecto 2018-2020 Coinvestigador(a)
EFFECT OF INTRAUTERINE ENVIRONMENT ON EPIGENETIC CHANGES OF SELECTED GENES LINKED WITH METABOLIC AND REPRODUCTIVE DYSFUNCTION IN THE OFFSPRING OF HYPERANDROGENIC MOTHERS=> A TRANSLATIONAL APPROACH FONDECYT (1151531) Proyecto 2015-2018 Coinvestigador(a)
EFFECT OF TESTOSTERONE ON PRO-INFLAMMATORY CYTOKINE EXPRESSION IN PRE-ADIPOCYTES FROM OBESE AND NON-OBESE WOMEN DURING REPRODUCTIVE AGE=> A POSSIBLE MECHANISM FOR INSULIN RESISTANCE IN POLYCYSTIC OVARY SYNDROME FONDECYT (11130126) Proyecto 2013-2016 Inv. Responsable


Perinatal androgen exposure and adipose tissue programming: Is there an impact on body weight fate? Maliqueo, M; Echiburú B.; Crisosto, N Review SCOPUS Expert Review of Endocrinology and Metabolism (2015)