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JOSE GALGANI

ASSOCIATE PROFESSOR

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Líneas de Investigación


Insulin resistance; Energy metabolism; NUTRITION; DIABETES Y OBESIDAD

Educación

  •  Nutrition, UNIVERSIDAD DE CHILE. Chile, 2007
  •  Nutricionista, UNIVERSIDAD DE CHILE. Chile, 1998

Experiencia Académica

  •   Associate Professor Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicine

    Santiago, Chile

    2012 - At present

  •   ASSISTANT PROFESSOR Full Time

    UNIVERSIDAD DE CHILE

    MEDICINE

    SANTIAGO, Chile

    2010 - 2012

  •   POST-DOCTORAL FELLOW Full Time

    LOUISIANA STATE UNIVERSITY

    PENNINGTON BIOMEDICAL RESEARCH CENTER

    BATON ROUGE, Estados Unidos

    2007 - 2009

  •   INSTRUCTOR Part Time

    UNIVERSIDAD DE CHILE

    INSTITUTE OF NUTRITION AND FOOD TECHNOLOGY

    SANTIAGO, Chile

    2007 - 2009

Experiencia Profesional

  •   RESEARCH ASSISTANT Full Time

    UNIVERSIDAD DE CHILE

    SANTIAGO, Chile

    1998 - 2003

Formación de Capital Humano


2011 - 2012: Tutor de tesis de Magister en Nutricion - INTA, U Chile. Giannella Leonelli.

2011 - 2012: Tutor de tesis de Magister en Nutricion - INTA, U Chile. Karen Cornejo.

2014: Tutor de tesis de Magister en Nutricion - PUC. Carmen Gómez.

2014: Tutor de tesis de Magister en Nutricion - PUC. Paloma Silva.

2013 - 2015: Tutor de tesis de Doctorado en Ciencias Médicas - PUC. Maria Luisa Mizgier.


Premios y Distinciones

  •   Young Investigator Award

    The Obesity Society.

    Estados Unidos, 2009

    This award includes US$25,000 for developing a research proposal. In that year, 58 applications were presented, and 8 were awarded.

  •   Featured Fellow

    INTERNATIONAL NUTRITION FOUNDATION

    Chile, 2009

    This is a distinction given to post-doctoral fellows funded by this institution, who have had a highlighted performance.


 

Article (67)

Direct Relationship Between Metabolic Flexibility Measured During Glucose Clamp and Prolonged Fast in Men
Impact of the Method Used to Select Gas Exchange Data for Estimating the Resting Metabolic Rate, as Supplied by Breath-by-Breath Metabolic Carts
Platelet Serotonin Levels Are Associated with Plasma Soluble Leptin Receptor Concentrations in Normoglycemic Women
Short-term impact of sucralose consumption on the metabolic response and gut microbiome of healthy adults
Association between zinc nutritional status and glycemic control in individuals with well-controlled type-2 diabetes
Metabolic flexibility to lipid availability during exercise is enhanced in individuals with high insulin sensitivity
Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals
Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals.
Validity of predictive equations for resting metabolic rate in healthy humans
Validity of predictive equations for resting metabolic rate in healthy humans.
Effect of Human Myotubes-Derived Media on Glucose-Stimulated Insulin Secretion.
Influence of a Gas Exchange Correction Procedure on Resting Metabolic Rate and Respiratory Quotient in Humans
Leptin/Adiponectin Ratios Using Either Total Or High-Molecular-Weight Adiponectin as Biomarkers of Systemic Insulin Sensitivity in Normoglycemic Women
Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells
Skeletal Muscle PGC1 alpha-1 Nucleosome Position and-260 nt DNA Methylation Determine Exercise Response and Prevent Ectopic Lipid Accumulation in Men
Assessment of the Role of Metabolic Determinants on the Relationship between Insulin Sensitivity and Secretion
Development and assessment of the disposition index based on the oral glucose tolerance test in subjects with different glycaemic status
Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation
Serotonin- and Dopamine-Related Gene Expression in db/db Mice Islets and in MIN6 beta-Cells Treated with Palmitate and Oleate
AGREEMENT BETWEEN INDIRECT CALORIMETRY AND PREDICTIVE EQUATIONS IN A SAMPLE OF SPANISH HEALTHY ADULTS
Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes
Fluoxetine Impairs Insulin Secretion without Modifying Extracellular Serotonin Levels in MIN6 beta-cells
Metabolic Effects of Cholecystectomy: Gallbladder Ablation Increases Basal Metabolic Rate through G-Protein Coupled Bile Acid Receptor Gpbar1-Dependent Mechanisms in Mice
PROPOSAL FOR A NEW FORMULA FOR ESTIMATING RESTING ENERGY EXPENDITURE FOR HEALTHY SPANISH POPULATION
Second Consensus of the Chilean Society of Endocrinology and Diabetes about insulin resistance
Second consensus of the chilean society of endocrinology and diabetes about insulin resistance [II Consenso de la sociedad chilena de endocrinología y diabetes sobre resistencia a la insulina]
Assessment of dietary intake and urinary excretion of sodium and potassium in adults
Assessment of dietary intake and urinary excretion of sodium and potassium in adults [Evaluación de la ingesta dietética y excreción urinaria de sodio y potasio en adultos]
Evaluación de la insulinemia post carga oral de glucosa como método diagnóstico de resistencia a la insulina
Evaluation of serum insulin levels after an oral glucose load for the diagnosis of insulin resistance
Evaluation of serum insulin levels after an oral glucose load for the diagnosis of insulin resistance [Evaluación de la insulinemia post carga oral de glucosa como método diagnóstico de resistencia a la insulina]
Exercise Sensitizes Skeletal Muscle to Extracellular ATP for IL-6 Expression in Mice
Potential role of skeletal muscle glucose metabolism on the regulation of insulin secretion
Relationship between whole-body macronutrient oxidative partitioning and pancreatic insulin secretion/beta-cell function in non-diabetic humans
Relationship between whole-body macronutrient oxidative partitioning and pancreatic insulin secretion/β-cell function in non-diabetic humans
Role of peripheral serotonin in the insulin secretion and glucose homeostasis
Skeletal Muscle Perilipin 3 and Coatomer Proteins Are Increased following Exercise and Are Associated with Fat Oxidation
Adipose Tissue Expression of Adipose (WDTC1) Gene Is Associated with Lower Fat Mass and Enhanced Insulin Sensitivity in Humans
Enhanced Skeletal Muscle Lipid Oxidative Efficiency in Insulin-Resistant vs Insulin-Sensitive Nondiabetic, Nonobese Humans
Insulin-Dependent H2O2 Production Is Higher in Muscle Fibers of Mice Fed with a High-Fat Diet
Muscle perilipin 3 is reduced using in vitro and in vivo exercise models and negatively associated with exercise lipid oxidation
Zinc as a potential coadjuvant in therapy for type 2 diabetes
A guide to analysis of mouse energy metabolism
Assessment of red blood cell glutathione status in insulin resistance
Effect of Short-Term Thyroxine Administration on Energy Metabolism and Mitochondrial Efficiency in Humans
Postprandial whole-body glycolysis is similar in insulin-resistant and insulin-sensitive non-diabetic humans
Relationship of serum adipocyte-derived proteins with insulin sensitivity and reproductive features in pre-pubertal and pubertal daughters of polycystic ovary syndrome women
Role of Skeletal Muscle Mitochondrial Density on Exercise-Stimulated Lipid Oxidation
Vanillin suppresses Kupffer cell-related colloidal carbon-induced respiratory burst activity in isolated perfused rat liver: anti-inflammatory implications
Assessment of EchoMRI-AH versus dual-energy X-ray absorptiometry to measure human body composition
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
Effect of a 3-day high-fat feeding period on carbohydrate balance and ad libitum energy intake in humans
Effect of capsinoids on energy metabolism in human subjects
Effect of dihydrocapsiate on resting metabolic rate in humans
Leptin Replacement Prevents Weight Loss-Induced Metabolic Adaptation in Congenital Leptin-Deficient Patients
The contribution of race and diabetes status to metabolic flexibility in humans
Urinary C-Peptide Excretion: A Novel Alternate Measure of Insulin Sensitivity in Physiological Conditions
Influence of Gender, Obesity, and Muscle Lipase Activity on Intramyocellular Lipids in Sedentary Individuals
Saturated fat and insulin resistance
Counter-intuitive effects of double heterozygous null Mc4r and Lep genes on diet-induced obesity and insulin resistance in C57BL/6J mice
Energy metabolism, fuel selection and body weight regulation
Metabolic Flexibility in Response to Glucose Is Not Impaired in People With Type 2 Diabetes After Controlling for Glucose Disposal Rate
Plasma arachidonic acid influences insulin-stimulated glucose uptake in healthy adult women
Acute effect of meal glycemic index and glycemic load on blood glucose and insulin responses in humans
Effect of glycemic index on whole-body substrate oxidation in obese women
Obesity and fatty acids in the etiology of insulin resistance
Single and multiple selenium-zinc-iodine deficiencies affect rat thyroid metabolism and ultrastructure

Abstract (7)

High vs. Low Responders to Exercise: Role of Epigenetic Modifications in Altering PGC1a Gene Expression and Intramyocellular Lipid Content in Skeletal Muscle
Exercise causes repositioning of the-1 nucleosome within the PGC1 alpha promoter in association with altered gene expression in skeletal muscle
Relationship of whole-body fuel oxidative partitioning with insulin secretion and beta cell function in non-diabetic humans
Effect of Short-term Thyroxine Supplementation on Substrate Utilization during Exercise
GLUCOSE DISPOSITION INDEX BASED ON THE ORAL GLUCOSE TOLERANCE TEST IN CHILEAN ADULTS
Differences in obesity risk factors and energy substrates utilization between obese nod control adult women
Differences in substrate oxidation and risk factors for obesity in Chilean low-socio-economic level women.

BookWhole (2)

Role of Saturated and Polyunsaturated Fat in Obesity-Related Inflammation
Role of n-6 and n-3 Polyunsaturated Fatty Acids in Type 2 Diabetes

EditorialMaterial (2)

Insights about weight loss-induced metabolic adaptation
Commentary on: Increase in Visceral Fat Per Se Does Not Induce Insulin Resistance in the Canine Model

Letter (2)

Should insulin resistance degree be taken into account for assessment of glycemic index?
Nutrition discussion forum

Note (1)

Progress and challenges in analyzing rodent energy expenditure

Proyecto (9)

Identifying systemic, cellular and molecular features of metabolically normal and abnormal overweight/obesity
Efecto de endulzantes no nutritivos sobre el metabolismo y la microbiota intestinal
Association between gene variants of the mitochondrial genome and proteome with insulin secretion/sensitivity indexes and glycemic-related traits
Assessment of peripheral glucose utilization as a determinant factor of glucose-stimulated insulin secretion in humans
Efecto de alimentos lácteos fortificados con fitoesteroles sobre los lípidos plasmáticos
Identification of genetic and metabolic risk factors of cholesterol gallstone disease in the Chilean population and development of novel strategies for primary prevention
PPAR-gamma coactivator-1 alpha and serotonin metabolism=> independent and combined effects on mitochondrial function and insulin secretion of pancreatic beta cells
Reproductive and metabolic features during the menopause transition and early post-menopausal period in PCOS women. Deepening in the pathophysiology of PCOS
Assessment of skeletal muscle fuel metabolism in insulin-resistant, offspring of type-2 diabetic parents and insulin-sensitive subjects

Review (7)

Contribution of brown adipose tissue to human energy metabolism
Insights on the Role of Putative Muscle-Derived Factors on Pancreatic Beta Cell Function
Biology and pathological implications of brown adipose tissue: promises and caveats for the control of obesity and its associated complications
The Implication of Brown Adipose Tissue for Humans
Effect of the dietary fat quality on insulin sensitivity
Metabolic flexibility and insulin resistance
Glycaemic index effects on fuel partitioning in humans
88
JOSE GALGANI

ASSOCIATE PROFESSOR

NUTRITION, DIABETES AND METABOLISM; AND UDA-CIENCIAS DE LA SALUD, NUTRICION Y DIETETICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

9
JOSE SANTOS

Full Professor

Department of Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

8
María Mizgier

Postdoctorate

Universidad de Los Andes

Santiago, Chile

5
Rodrigo Fernández

Académico

Departamento de Kinesiología

Universidad Finis Terrae

Santiago, Chile

3
Victor Cortes

Associate professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

3
Pamela Rojas

Profesor asistente

Nutricion

UNIVERSIDAD DE CHILE

Santiago, Chile

3
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

3
Fernando Carrasco

Médico nutriólogo

Nutrición y Vida Saludable

Clínica Las Condes

Santiago, Chile

3
MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Jose Suazo

Profesor Asociado

Instituto de Investigación en Ciencias Odontológicas

Facultad de Odontologia, Universidad de Chile

Santiago, Chile

2
Alejandra Lanas

Profesor asistente

Medicina Interna

Hospital Clínico de la Universidad de Chile

Santiago, Chile

2
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Manuel Ruz

Professor

Nutrition

DEPARTAMENTO DE NUTRICIÓN, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

2
Mariana Casas

Assistant Professor

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Mauricio Castro

Investigador

Universidad Finis Terrae

Santiago , Chile

2
Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

2
Jorge Sapunar

Head of Unit

Investigación del Cáncer

Instituto Oncológico Fundación Arturo López Pérez

Santiago, Chile

2
José Suazo

Profesor Asociado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

2
Alexis Diaz

PhD stundent

Fisiología

universidad de Chile

Santiago, Chile

1
Eduardo Aranda

Biochemist

Hematology

P. UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Javier Parada

Profesor asociado

ICYTAL

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Giovanna Valentino

Profesor Docente Asistente

Ciencias de la Salud

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Diego Garcia

Associate Professor

Nutricion

Universidad de Chile

Santiago, Chile

1
Fernando Pizarro

Profesor Titular

INTA-UNIVERSIDAD DE CHILE

Santiago, Chile

1
Daniel Garrido

Associate Professor

Chemical and Bioprocess Engineering

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Gina Leonelli

Director de Carrera

Ciencias Agropecuarias y Acuícolas

Universidad Católica de Temuco

Temuco, Chile

1
Álvaro Pérez

Associate Professor

Nutrition

Universidad de Chile

Santiago, Chile

1
Cristian Campos

Entrenamiento Post Doctorado

Fisiología

Universidad de Chile

Santiago, Chile

1
Silvana Zanlungo

Full Professor

Gastroenterology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Sonja Buvinic

Associate Professor

Institute for Research in Dental Sciences

Universidad de Chile

Santiago, Chile

1
Rodrigo Valenzuela

Profesor Asociado

Nutrición

Universidad de Chile

Santiago, Chile

1
Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

1
César Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

1
Juan Valderas

diabetologist

asociacion de diabeticos de chile

Santiago, Chile

1
Karen Basfi-Fer

académico

Departamento de Nutrición

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Fabián Jaña

Profesor Asistente

Departamento de Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

1
Bárbara Echiburú

Profesor Asistente

Medicina Interna

Universidad de Chile

Santiago, Chile

1
Nicolas Crisosto

Profesor Asistente

Medicina Interna Occidente

Universidad de Chile

Santiago, Chile

1
PABLO TAPIA

Investigador postdoctoral

Centro de Biología Celular y Biomedicina (CEBICEM)

Universidad San Sebastián

Santiafgo, Chile

1
Gladys Tapia

Academica

Farmacología Molecular y Clínica

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Ricardo Uauy

Professor

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Raquel Burrows

PROFESOR TITULAR

Instituto de Nutricion y Tecnologia de los Alimentos

universidad de

Santiago, Chile

1
Paulina Villaseca

Investigadora

Centro de Excelencia en Biomedicina de Magallanes (CEBIMA)

Punta Arenas, Chile