Caveolin-1 as a tumor suppressor and metastasis promoter/Helicobacter pylori in gastric cancer/inflammation-associated changes in Caveolin-1 function

Post-doctoral fellows

1) Mauricio Henríquez (2006-2009 : Universidad de Chile). Working on alternative forms of cell death induced by ceramides (FONDAP 15010006). Fondecyt post-doctoral fellow award Nr. 3050037 (2007-2009) to study role of P2X7 receptors and ATP in FasL-induced necrosis. Position as Assistant Professor at the ICBM, Universidad de Chile since January 2009.
2) Vicente Torres (2009-2013: Universidad de Chile). Short additional post-doctoral training period working on effects of caveolin-1 as a tumor suppressor (FONDAP 15010006). As of 2010 funded by Fondecyt Chile Project Nr. 79090021 (2010-2012) “Renovacion academica para el desarollo de la medicina molecular“ financial support to promote integration of young scientists (post-doctoral fellows) into academia. Position as Assistant Professor at the Faculty of Odontology, Universidad de Chile since March 2011.
3) Manuel Valenzuela (2009-2011: Universidad de Chile). Continuation of Ph.D. thesis project working on mechanisms underlying cell death induced by Helicobacter Pylori in gastric epithelial cells for over a year. Subsequently, post-doctoral position in the laboratory of Dr. Pedro Buc Calderon, Université Catholique de Louvain, Belgium.
4) Denisse Bravo (2009-2011: Universidad de Chile). Continuation from Manuel working on mechanisms underlying cell death induced by Helicobacter Pylori in gastric epithelial cells. Position as assistant professor at the Faculty of Odontology, Universidad de Chile since March 2011.
5) Jimena Castillo (2013-2015: Universidad de Chile). Continuation from Carlos Sanhueza and Maria Ines Diaz’s work evaluating CAveolin-1 translocation to ER in hypoxia, the regulation there of eNOS and the connection to HIF-1a inhibition.
6) Simon Guerrero (2013-2015: Universidad de Chile). Collaboration with Marcelo Kogan from the Fcultad de Odontologia, Universidad de Chile, evaluating the potential of gold nanoparticles to track melanoma metastasis in vivo.

7) 2015-2018 Fondecyt Chile Project for post-doctoral fellows Nr. 3160384 (to Jimena Bravo; host laboratory A. Quest) “Role of Helicobacter pylori gamma glutamyl transpeptidase in autophagy of human gastric cells and the progression of precancerous lesions to gastric cancer” (ranked Nr.1 in study section medicine G2/G3).
8) 2017-2020 Fondecyt Chile Project for post-doctoral fellows Nr. 3170141 (to Paula Diaz; host laboratory A. Quest) “The role of PKR-like ER kinase (PERK) in Helicobacter pylori induced gastric cell death and progression of precancerous lesions to gastric cancer” (ranked Nr.5 in study section medicine G2/G3).
9) 2018-2022 Fondecyt Chile Project for post-doctoral fellows Nr. 3180656 (to Lorena Orostica; host laboratory A. Quest) “Rol del ambiente inflamatorio en la expresión de CAV1 y la progresión del Cáncer de Vesícula Biliar” (ranked Nr.2 in study section medicine G1).
10) 2018-2022 Fondecyt Chile Project for post-doctoral fellows Nr. 3180783 (to Alejandra Sandoval; host laboratory A. Quest) “The role of the ” Angiotensin II type 2 receptor in the molecular pathogenesis of human gastric carcinoma (ranked Nr.1 in study section medicine G2/3).
11) 2019-2022 Fondecyt Chile Project for post-doctoral fellows Nr. 3190330 (to Layla Simon; host laboratory A. Quest) “Caveolina-1 induce cambios metabólicos en células de cáncer que favorecen la metástasis” (ranked Nr.11 in study section Biology 2).
12) 2022-2025 Fondecyt Chile Project for post-doctoral fellows Nr. 3220587 (to Karen Bolaños; host laboratory A. Quest) “Photothermal effect and Extracellular vesicles to control the targeted release of doxorubicin to tumor cells” (ranked Nr. 5 in study section Chemistry).

PhD thesis students (finished)

1. Diego Rodriguez (April 2009): “Caveolina-1 inhibe la proliferación y promueve muerte celular mediante la regulación negativa de ciclooxigenasa-2 y survivina” (AQ thesis director/LLeyton co-director).
2. Manuel Valenzuela (May 2009): “Estudio del papel de survivina y caveolina-1 en la apoptosis inducida por Helicobacter pylori en celulas gastricas” (AQ thesis director/HToledo co-director).
3. Jorge Gutierrez (June 2009): “Rol de PKCalfa en la regulación de la expresión de caveolina-1 en celulas de cancer de endometrio, mama y colon“ (AQ thesis director/SLavandero co-director)
4. Rodrigo Herrera-Molina (August 2009) “La interaccion molecular integrina aVb3/Thy-1 en el contacto celula-celula entre astrositos y neuronas participa en la inhibición del crecimiento de neuritas y la retraccion de procesos neuronales s traves de una via de señalización que involucra a src“(AQ thesis codirector/LL director).
5. Alejandra Valdivia (June 2010): “Transduccion de senales mediada por Thy-1 en astrocitos: Participación secuencial de la integrina avb3 y sindican-4 en la formación de adhesiones focales y fibras de estrés” (AQ thesis codirector/LL director).
6. Adam Aguirre (June 2011) : “FasL promueve muerte celular en celulas linfoides via liberacion de ATP y activacion de receptores P2X7” (AQ thesis director/Mauricio Henriquez co-director).
7) Lorena Lobos (June 2011) :”La E-cadherina potencia a Caveolina-1 como supresor de tumores y reduce su efecto promotor de metastasis” ” (AQ thesis director/Lisette Leyton co-director).
8) Paulina Ormazabal (December 2011) “Evaluacion de moleculas relacionadas con la via metabolica de la insulina en celulas endometriales y en endometrio de mujeres con syndrome de ovario poliquistico“ Ph.D. advisor Margarita Vega, AQ co-advisor.
9) Jaime Gonzalo Fernandez (Jan 2012) “Survivina promueve la actividad transcripcional de b-catenina favoreciendo de esta manera angiogenesis” (AQ thesis director, co-advisor Julio Tapia).
10) Lorena Aguilar (Nov. 2012) “La terapia experimental conjunta de Calreticulina de Trypanosoma Cruzi y la inmunizacion con Survivina inhibe el crecimiento in vivo de un melanoma experimental murino” (AQ and Arturo Ferreira thesis advisors).
11) Sergio Nunez (Dec 2012) “Caveolina-1 sensibiliza a las células Min6 a la muerte inducida por ácidos grasos libres” (AQ director).
12) Carlos Sanhueza (Sept. 2013) “Caveolina-1 reduce la transcripcion dependiente de HIF-1a en un mecanismo dependiente del oxido nitrico en celulas tumorales” (AQ thesis advisor/ LL co-advisor).
13) Milene Kong (Jan 2014). “Thy-1 induce la migración de los astrocitos activando vías de señalización que involucran a FAK, PI3K, Tiam1 y Rac1” (LL thesis advisor/ AQ co-advisor).
14) Ph. D. Advisor of Rina Ortiz (Oct 2010 – Jan 2015) Ph.D. in Farmacology (funded by CONICYT/FONDAP; Mecesup travel fellowship) “Caveolin-1 expression promotes migration of B16F10 mouse melanoma cells in vitro and metastasis in vivo in C56BL6 mice in manner that requires phosphorylation on tyrosine by src family kinases” Thesis co-advisor Lisette Leyton, ICBM, Universidad de Chile. Teaching position at the Universidad de Valparaiso.
15) Ph. D. Co-advisor of Alvaro Alvarez (Oct 2010 – Jan 2015) Ph.D. in Farmacology (funded by CONICYT/FONDAP; Mecesup travel fellowship) “Role of the receptor P2X7 in astrocyte responses triggered by Thy-1 in an inflammatory environment” Thesis advisor Lisette Leyton, ICBM, Universidad de Chile. Teaching position at private university.
16) Ph. D. Advisor of Jorge Diaz (Dec 2011 – Mayo 2015) Ph.D. in Biochemistry (funded by CONICYT/FONDAP; MECESUP travel fellowship) “Caveolin-1 enhanced migration of metastatic tumor cells requires phosphorylation on tyrosine-14 and activation of the Rab5/Tiam-1/Rac1 axis” Thesis co-advisor Vicente Torres, Facultad de Odontologia, Universidad de Chile.
17) Ph. D. Co-advisor of Cesar Oyarce (Mar 2013 – July 2015) Ph.D. in Biomedical Sciences (funded by CONICYT/FONDAP) “Caveolin-1 promotes dendritic cell maturation by inhibiting b-catenin/Tcf-Lef-dependent transcription” Thesis advisor Alvaro Lladser, Fundacion Ciencia y Vida.
18) Ph. D. Co-advisor of Horacio Maldonado (Oct 2011 – Sept 2015) Ph.D. in Biochemistry (funded by CONICYT/FONDAP; PhD travel fellowship) “Study of signaling mechanisms associated with retraction/inhibition of neurite outgrowth mediated by ?v?3/Thy-1 interaction in neuronal cells in culture” Thesis advisor Lisette Leyton, ICBM, Universidad de Chile.
19) Ph. D. Co-advisor of Roberto Bravo (Oct 2011 – Oct 2015) Ph.D. in Biochemistry (funded by CONICYT/FONDAP) “Compartmentalizacion of physical and metabolic coupling between ER and mitochondria in cancer cells” Thesis advisor Sergio Lavandero, ICBM, Universidad de Chile.
20) Ph. D. Advisor of Maria Ines Diaz (Aug 2008 – Dec 2015) Ph.D. in Biochemistry (funded by Mecesup/CONICYT/FONDAP fellowships; Mecesup/DID University of Chile travel fellowships; CONICYT apoyo de tesis fellowship) “Role of the unfolded protein response in tumor suppression by caveolin-1” Thesis co-advisor Claudio Hetz, ICBM, Universidad de Chile. Teaching position in private university.
21) Ph. D. Advisor of Natalia Diaz (Oct 2012 – July 2016) Ph.D. in Biochemistry (funded by CONICYT/FONDAP; proyecto REDES travel fellowship) “Inhibition of Caveolin-1 enhanced migration of metastatic tumor cells by E-cadherin involves suppression of phosphorylation on tyrosine-14 and the Rab5/Tiam-1/Rac1 axis” Thesis co-advisor Lisette Leyton, ICBM, Universidad de Chile.
22) Ph. D. Advisor of Jimena Canales (Oct 2012 – Oct 2016) Ph.D. in Farmacology (funded by CONICYT/FONDAP; xxxxx travel fellowship) “Helicobacter pylori induced iNOS expression and NO production enhances HIF-1?-dependent transcription transition to a more mobile cell phenotype” Thesis co-advisor Denisse Bravo, ICBM, Universidad de Chile.
23) Ph. D. Advisor of Yeniffer Avalos (Oct 2012 – Oct 2016) Ph.D. in Farmacology (funded by CONICYT/FONDAP; PhD travel fellowship) “Caveolin-1-enhanced autophagy via reduced iNOS signaling favors caveolin-1-mediated tumor suppression”
24) Ph.D. Co-advisor of Andrea Orellana (Mar 2014 – November 2016) PhD in Pharmacology (funded by CONICYT, fellowship from Ecuador/FONDAP) “Modulation of the expression of SLC5A8, a gene associated with gastrointestinal cancer, by the infection with Helicobacter pylori in symptomatic and asymptomatic children”. Prize for Best Oral Presentation at the 365 World Congress of Pediatric Infectious Diseases (WCPID), Brazil, 2015. Thesis advisor Miguel O’Ryan, ICBM, Universidad de Chile. Now Assistant professor at the Universidad de Guayaquil, Ecuador.
25) Ph. D. Advisor of Victor Diaz (Jan 2014 – Sept 2017) Ph.D. in Biochemistry (funded by CONICYT/ANILLO/FONDAP) “Development of nanoparticles based on Quantum Dots to stady CAV1-enhanced metastasis of B16F10 cells in vivo” Thesis co-advisor Jose Miguel Perez, Universidad Andres Bello.
26) Ph. D. Co-advisor of Francesca Burgos (April 2014 – Oct 2017) Ph.D. in Biochemistry (funded by CONICYT/FONDAP) “The astrocyte proteoglycan Syndecan-4 participates in the inhibition of neuronal process outgrowth induced by engagement of neuronal Thy-1 and astrocyte avb3 integrin” Thesis advisor Lisette Leyton, ICBM, Universidad de Chile. Oriana Joisseau Young Female Scientist Award 2013 for Excellence in Biochemistry. PEW award Latin American Fellows Program in the Biomedical Sciences 2018. Now post-doc at UCSF in the USA.
27) Ph.D. Advisor of America Campos (Dec 2014 – April 2018) Ph.D. in Biochemistry (funded by CONICYT/FONDAP) “The role of CAV1 in exosome formation and malignancy of breast cancer cells” Best Oral presentation award (2nd place) Chilean Cell Biology Society 2017. Thesis co-advisor Lorena Lobos, ICBM, Universidad de Chile, Fundacion Ciencias para la Vida, Universidad de Desarollo. Post-doc in the lab for one year. Then got Becas Chile fellowship to go to the University of Queensland, Brisbane, Australia.
28) Roger Yefi (August 2018) “Regulation of tumor progression in colon cancer by the proteins CK2 and Caveolin-1” (Thesis advisors Julio Tapia, AQ).
29) Ph.D. Advisor of Samuel Martinez (July 2015 – Sept. 2018) Ph.D. in Molecular Biotechnology (funded by FONDAP ACCDiS) “Study of the anti-metastatic potential of the AT2R as a target to block melanoma metastasis”. Thesis co-advisor Sergio Lavandero, Facultad de Quimicas Farmaceuticas, Universidad de Chile. Short post-doc with Lisette Leyton, now doing post-doc at The Albert Einstein Colleage, USA.
30) Ph.D. Co-Advisor of Maritza Garrido (April 2016 – April 2019) Ph.D. in Pharmacology (funded by CONICYT/FONDAP) “Role of survivin/COX2 in NGF-induced angiogenesis in ovarian cancer” Thesis advisor Carmen Romero, Hospital Clinico, Universidad de Chile. Now has faculty position in the Hospital Clinico, Universidad de Chile.
31) Ph.D. Co-Advisor of Maximilian Arce (July 2016 – June 2019) Ph.D. in Biological Sciences PUC (funded by CONICYT/FONDAP) “FXa promotes metastasis through endothelial cell activation” Thesis advisor Gareth Owen, Facultad de Ciencias Biologicas, PUC. Now doing post-doc in the Univerity of Uppsula, Sweden.
32) Ph.D. Co-Advisor of Pablo Lara (June 2015 – June 2020) Ph.D. in Pharmacology (funded by CONICYT/FONDAP) “Exosomes from metastatic B16F10 cells as vectors for specific targetting of gold nanoparticles and curcumin to lung tumors” Thesis advisor Marcelo Kogan, Facultad de Quimicas Farmaceuticas, Universidad de Chile. Now post-doc in Holland, University of Leiden.
33) Ph.D. Co-Advisor of Monica Villa (June 2015 – July 2020) Ph.D. in Pharmacology (funded by CONICYT) “Evaluation of the oxidized low-density lipoprotein receptor, LOX-1, as a new therapeutic target in cardiac fibrosis” Thesis advisor Lorena Garcia, Facultad de Quimicas Farmaceuticas, Universidad de Chile. Now teaching at private University.
34) Ph.D. advisor of Ricardo Huilcaman (Jan 2018 – November 2020). Ph. D. in Biomedical sciences (funded by CONICYT/FONDAP) “Caveolin-1 phosphorylation of tyrosine-14 modulates the biochemical properties of extracellular vesicles from metastatic melanoma cells to promote malignancy of less metastatic cells” Thesis co-advisor Lisette Leyton, ICBM, Faculty of Medicine, Universidad de Chile. Now doing post-doc in the lab.
35) Ph.D. advisor of Renato Burgos (Agosto 2018 – April 2021). Ph. D. in Farmacology (funded by PhD program/FONDAP/Fcyt) “Caveolin-1-containing exosomes from breast cancer cells increase migration/invasion via Cyr61 activation of the integrin avb3” Thesis co-advisor Lisette Leyton, ICBM, Faculty of Medicine, Universidad de Chile.
36) Ph.D. advisor of Maria Fernanda Gonzalez (Sept 2018 – Sept 2021). Ph. D. in Biochemistry (funded by CONICYT/FONDAP) “Extracellular vesicles from H. pylori-infected gastric cells promote inflammation and progression of gastric cancer” Thesis co-advisor Alejandro Corvalan, Faculty of Medicine, PUC.
37) Ph.D. Co-advisor of Cristopher Soto (Oct 2017 – May 2022) Ph.D. in Biochemistry (funded by CONICYT/FONDAP) “Study of the effects of Helicobacter pylori on the virulence of Porphyromonas gingivalis and their participation in the progression of periodontal disease” Thesis advisor Denisse Bravo, Faculty of Odontology, Universidad de Chile.
38) Ph.D. co-advisor of Magda Carolina Diaz (April 2020 – June 2022). Ph. D. in Biomedical Sciences (funded by CONICYT/FONDAP) “Role of Polycistin-1 in tubulogenesis and the distribution of type-L calcium channels between transverse tubules and the membrane fraction enriched in caveolas” Thesis advisor Zully Pedroso, Faculty of Medicine, University of Chile.

PhD thesis students (in progress)

39) PhD thesis advisor of Daniela Herrera (June 2019-Mar 2023) PhD in Biomedical. Sciences (funded by CONICYT/FONDAP) “H. pylori infection induces E-cadherin internalization and degradation via Rab5 in gastric cancer” Co-advisor Vicente Torres.
40 PhD thesis advisor of Sofia Sanheza (Oct 2021-Mar 2024) PhD in Biomedical. Sciences (funded by CONICYT/FONDAP) “Role of Caveolin-1 in extracelular vesicles from adipocytes in the polarization of macrophages and inflammation in breast cancer” Co-advisor Mariane Cifuentes.
42) PhD thesis co-advisor of Daniela Leon (Oct 2021-Mar 2024) PhD in Biochemistry (funded by CONICYT/FONDAP) “Exosomes isolated from B16F10 cells overexpressing Caveolin-1 which contain gold nanorods as tools for theranosis of metastatic nodules in the lung” Advisor Marcelo Kogan.

Masters thesis students (finished)

1) Masters thesis adviser of Claudia Duran (May 2007 – Sept 2009) Magister in Biomedical Sciences, Microbiology “Role of caveolae in the internalization of pathogenic E.coli strains”. Thesis co-advisor Roberto Vidal, ICBM, Universidad de Chile. Continued working with Roberto Vidal.
2) Master’s thesis Co-advisor of Astrid Schmied (Mar 2011 – Nov 2013) “Caracterizacion del tipo de murte cellular enn linfocitos de sujetos con historia de cancer de piel y probable enfermedades de alzheimer” Thesis advisor Dr. Maria Isabel Behrens.
3) Masters student co-advisor of Paulina Cerda (Dec 2014- April 2016). MSc in Clinical Biochemistry (funded by FONDAP) “On the inverse relationship between survivin and Reprimo in gastric cancer” Thesis advisor Alejandro Corvalan, PUC. Now PhD student with Lorena Garcia.
4) Co-adviser for Masters thesis of Sebastian Cruz (Oct 2015-March 2017). (funded by FONDAP). Role of CAV1 in the chemiotaxis of dendritic cells towards lymph nodes. Alvaro Lladser Advisor. Now doing PhD thesis in Australia.
5) Co-advisor for masters thesis of Sujey Palma (Mar 2016-Oct 2017). (funded by FONDAP) “Isolation of exosomes containing functionalized gold nanoparticles from B16F10 cells” Advisor Marcelo Kogan.
6) Advisor for masters thesis of Carla Jorquera (Dec. 2016-Nov. 2017). (funded by FONDAP) Induction of HIF-1a by the Helicobacter pylori urease virulence factor. Co-advisor Sergio Nunez-Wehinger. Now doing PhD thesis University of Leiden, Holland.
7) Co-advisor for masters thesis of Olinda Nuñez (Dec. 2016-Dec. 2018). (funded by CEMC) “MAPKs activadas median la susceptibilidad por Caveolina-1 a muerte celular inducida por palmitato en células MIN6” Advisor Sergio Nunez-Wehinger. Now returned to Honduras.
8) masters advisor of Antonio Hidalgo (Aug 2018 – Mar 2022). MSc in Biochemistry (funded by FONDAP) “Study of the anti-bacterial effect of Curcumin nanoemulsions and chitosan nanocapsules on Helicobacter pylori” Thesis co-advisor Felipe Oyarzun, Faculty of Chemical and Pharmaceutical Sciences, Universidad de Chile.
9) Co-advisor for masters thesis of Damian Perez (Mar 2019-Jan 2022). (funded by FONDAP) “Functionalization of exosomes from B16F10 cells with folic acid-conjugated gold nanorods” Advisor Marcelo Kogan.

Undergraduate thesis students (finished)

1) Thesis co-advisor for Hery Urra (Jan 2007 – May 2009) “Rol de caveolina-1 en migracion cellular de celulas metastaticas de cancer de mama y astrocitos” (Universidad de Valparaiso, Chile)
2) Thesis advisor for Natalia Diaz (May 2008 – March 2010) “Regulacion de la re-expresion de caveolina-1 en celulas tumorales” (Universidad de Valparaiso, Chile)
3) Visiting student, Tania Yareli (August-September, 2009) from Universidad Autonoma de Sinaloa, Mexico.
4) Visiting student, Cristina Gomez (October-December, 2009) from Universidad de Medellín, Colombia
5) Visiting student Stefan Brueck (March-June, 2010) from the Institute of Biochemistry and Molecular Biology of the Medical School of the RWTH Aachen University, Germany.
6)Thesis advisor for Hernan Huerta (August 2010 – May2012) “Estudio del rol de la proteina PKC? en la re-expresion de Caveolin-1 inducida por el ester de forbol 4?-TPA” (Universidad de Santiago, Chile)
7) Adviser for Unidad de Investigacion of 2nd year pre-medical students Victor Vicencio and Ruben Valenzuela (May-Dec 2010) “Estudio de los mecanismos moleculares de angiogenesis y metastasis en celulas tumorales” (Universidad de Chile, Chile)
8) Adviser for Unidad de Investigacion of 2nd year pre-medical students Mackarenna Norambuena Guamparito and Constanza Segura Rios (May-Dec 2011) “Caveolina-1 reduce la actividad de HIF-1 inducida por hipoxia en
células de melanoma B16F10” (Universidad de Chile, Chile)
9) Adviser for Unidad de Investigacion of 2nd year pre-medical students Wendy Soruco Guamparito and Konnie Yanez (May-Dec 2012) “El rol de Survivina y ?-Catenina en proliferación celular, apoptosis y resistencia a drogas en células de Leucemia Linfoblástica” (Universidad de Chile, Chile).
10) Masters thesis co-adviser for Samantha Gonzalez (May 2012- April 2013) “Rol de la proteina survivina en la inhibicion de la apoptosis por Porphyromonas gingivalis” (Universidad de Chile, Chile)
11) Adviser for Unidad de Investigacion of 2nd year pre-medical students Diego Urbina – Andrés Vargas (May-Dec 2013) “Rol de la proteína caveolina-1 en la migración e invasión de células metastásicas” (Universidad de Chile, Chile).
12) Adviser for one month summer research stage of Students in Biochemistry (Dec 2013 – Mar 2014) Ana Victoria Rojas, Eliseo Parra, Francisco Cornejo.
13) Adviser for Unidad de Investigacion of 2nd year pre-medical students xxxxxxxxxxx (May-Dec 2014) “Estudio del eje Caveolina-1/Rab5 en la migración e invasion de células metastásicas” (Universidad de Chile, Chile).
14) Undergraduate thesis co-adviser for Ana Victoria Rojas (June 2016- August 2018) “P. gingivalis O-antigen participates in the modulation of IL-8 and migration of gingival epithelial cells” (Universidad de Chile, Chile). Thesis advisor Denisse Bravo.
15) Undergraduate thesis co-adviser for Sujey Fernanda Palma Flores (June 2016- October 2017) “Isolation of exosomes containing functionalized gold nanoparticles from B16F10 cells” (Universidad de Chile, Chile). Thesis advisor Marcelo Kogan.
16) Co-advisor for undergraduate thesis of Damian Perez (June 2019- Aug 2021) (funded by FONDAP) “Funcionalizacion de exosomas de células B16F10 con AuNPs-acido fólico” Advisor Marcelo Kogan (Universidad de Chile, Chile).

UNDERGRADUATE TEACHING

1) Curso de Fisiológica y Patológica Integrada de la Facultad de Química Farmacéutico: Bases Moleculares del Cáncer (Marzo 2009, 3 h- directa, 125 alumnos).
2) “Unidades de Investigación 2010” para estudiantes del 2ndo ano de la carrera de medicina.
3) Clase magistral para estudiantes del 1er ano de medicina “Bases celulares y moleculares del cáncer” (Nov. 2010, 2 horas directas, 125 alumnos)
4) “Unidades de Investigación 2010” para estudiantes del 2ndo ano de la carrera de medicina
5) “Unidades de Investigación 2011/2012” para estudiantes del 2ndo ano de la carrera de medicina
6) Bases Científicas de Medicina I: Capitulo Biología Celular y Molecular (Nov-Dec 2011/2012).
7) “Unidades de Investigación 2012” para estudiantes del 2ndo ano de la carrera de medicina
8) Curso de Bioquímica de la Facultad de Química Farmaceutica: Compartmentalizacion en transduccion de senales (May 2012, 2 horas directa, 20 alumnos).
9) Bases Científicas de Medicina I: Capitulo Biología Celular y Molecular (Nov-Dec 2012).
10) Bases Científicas de Medicina I: Capitulo Biología Celular y Molecular (Nov-Dec 2013).
11) Bases Científicas de Medicina I: Capitulo Biología Celular y Molecular (Oct 2014).
12) “Unidades de Investigación 2014” para estudiantes del 2ndo ano de la carrera de medicina
13) Clase magistral para estudiantes del 1er ano de medicina 2014 “Mecanismos de la señalización celular” (Oct 24, 2 horas directas, 25 alumnos)
14) “Unidades de Investigación 2015” para estudiantes del 2ndo ano de la carrera de medicina
15) Clase magistral para estudiantes del 1er ano de medicina 2015 “Mecanismos de la señalización celular” (Oct 30, 2 horas directas, 125 alumnos)
16) “Unidades de Investigación 2016” para estudiantes del 2ndo ano de la carrera de medicina
17) Clase magistral para estudiantes del 1er ano de medicina 2016 “Mecanismos de la señalización celular” (Nov 07, 2 horas directas, 125 alumnos)
18) “Unidades de Investigación 2017” para estudiantes del 2ndo ano de la carrera de medicina
19) Clase magistral para estudiantes del 1er ano de medicina 2017 “Mecanismos de la señalización celular” (Oct 06, 2 horas directas, 125 alumnos)
20) Revision bibliografica 1er medicina 2017 “Exosomas en Cancer”. Tutor Rosario Matte. Integ, Josefa Clotet Morales, Amanda Collingwood-Selby Lois, Pablo Chamorro, Eguzki Mena, Isidora Contador Baeza
21) “Unidades de Investigación 2018” para estudiantes del 2ndo ano de la carrera de medicina
22) Clase magistral para estudiantes del 1er ano de medicina 2018 “Mecanismos de la señalización celular” (Nov 09, 2 horas directas, 125 alumnos).
23) Revision bibliografica 1er ano medicina 2018 “Mecanismos de induccion de cancer gastrico por Helicobacter pylori”. Tutor Josefa Lopez. Integrantes, Francisca Martinez, Josefina Oliva, Isidora Poblete, Catalina Mandiola, Carlos Reyes.
24) “Unidades de Investigación 2019” para estudiantes del 2ndo ano de la carrera de medicina
25) Clase magistral para estudiantes del 1er ano de medicina 2019 “Mecanismos de la señalización celular” (Oct 07, 2x1.5 horas directas, 125 alumnos).
26) Revision bibliografica 1er ano medicina 2019 “Exosomas en Metastasis”. Tutor María de los Ángeles Gatica. Integrantes, Nicolás Cholaky, Juan Pedro Espinoza, Bárbara Paredes, Fernanda Quiroz, Martín Vergara.
27) “Unidades de Investigación 2020” para estudiantes del 2ndo ano de la carrera de medicina
28) Clase magistral para estudiantes del 1er ano de medicina 2020 “Mecanismos de la señalización celular” clase virtual en 3 capsulas de approx 30 min cada uno y una sesión de preguntas (Jan 2021, 2x1.5 horas directas, 125 alumnos)
29) “Unidades de Investigación 2021” para estudiantes del 2ndo ano de la carrera de medicina
30) Clase magistral para estudiantes del 1er ano de medicina 2021 “Mecanismos de la señalización celular” clase virtual en approx 120 min con una sesión de preguntas (Nov 2021, 2 horas directas, 125 alumnos).
31) Revision bibliografica 1er ano medicina 2021 “Rol de Caveolina-1 exosomal en promover metastasis”. Tutor Alexandra Gotschlich K. Integrantes, Constanza Almuna, Rodrigo Bravo, Antonia Riquelme, Andrés Salvatierra, Cristian Sánchez y Magdalena Schwerter
32) Revision bibliografica 1er ano medicina 2021 “Helicobacter pylori en enfermedades extragastricas”. Tutor Idan Sutin. Integrantes, Constanza Almuna, Rodrigo Bravo, Antonia Riquelme, Andrés Salvatierra, Cristian Sánchez y Magdalena Schwerter.
33) Clase magistral para estudiantes del 1er ano de medicina 2022 “Mecanismos de la señalización celular” clase virtual en approx 120 min (Oct 2022, 2 horas directas, 125 alumnos)
34) “Unidades de Investigación 2022” para estudiantes del 2ndo ano de la carrera de medicina
35) Revision bibliografica 1er ano medicina 2022 “Rol de Caveolina-1 exosomal en promover metastasis”. Tutor Sofia……. Integrantes,….
36) Revision bibliografica 1er ano medicina 2022 “Helicobacter pylori en enfermedades extragastricas”. Tutor Daniela….. Integrantes, ………

POST-GRADUATE LECTURE COURSES (Chile)

1) Co-organizer (together with Sergio Lavandero) of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (April - May, 2014) and “Signalling in Biomedicine” (June-July, 2014). Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer” ICBM, Facultad de Medicina, U. de Chile. These two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas as well as Ciencias. This course represents a contribution of the anillo group NEMESIS(CEMC) to post-graduate education in four faculties of the Universidad de Chile.

2) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell and Molecular Biology” (April - May, 2014). Coordinator of the section “Dynamics of Cytoplasm, Cytoskeleton, and cell migration”. Lecturer for the following topics; “Organization of the plasma membrane – microdomains - cell migration”. This course is taught to students primarily from the Facultad de Ciencias, Ciencias Químicas y Farmacéuticas, Farmacología and Medicine. This course represents a contribution of the anillo group NEMESIS(CEMC) to inter-faculty post-graduate education at the Universidad de Chile.

3) Lecturer in post-graduate course entitled “Advanced Molecular Pharmacology” organized by Guillermo Diaz (August 2014), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile. Topic: “Cancer”

4) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by Lisette Leyton (Oct-Nov 2014), at Facultad de Medicina, Universidad de Chile.

5) Lecturer and organizer of post-graduate course entitled “Reading and Discussing papers in English” organized by Lisette Leyton (Oct-Nov 2014), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

6) Lecturer and organizer of post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (Oct-Nov 2014), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

7) Co-organizer (together with Sergio Lavandero) of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (April - May, 2015) and “Signalling in Biomedicine” (June-July, 2014). Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer” ICBM, Facultad de Medicina, U. de Chile. These two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas as well as Ciencias. This course represents a contribution of the anillo group NEMESIS/CEMC and the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

8) Lecturer in post-graduate course entitled “Topics in Biomedical Research” organized by Miguel Concha (May 2015), at Facultad de Medicina, Universidad de Chile. Topic: “Cell migration, invasion and metastasis”

9) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell and Molecular Biology” (Sept - Dec, 2015). Coordinator of the section “Dynamics of Cytoplasm, Cytoskeleton, and cell migration”. Lecturer for the following topics; “Organization of the plasma membrane – microdomains - cell migration”. This course is taught to students primarily from the Facultad de Ciencias, Ciencias Químicas y Farmacéuticas, Farmacología and Medicine. This course represents a contribution of the anillo group NEMESIS/CEMC and the FONDAP group ACCDiS/CEMC to inter-faculty post-graduate education at the Universidad de Chile.

10) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by Lisette Leyton (Oct-Nov 2015), at Facultad de Medicina, Universidad de Chile.

11) Lecturer and organizer of post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (Oct-Nov 2015), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

12) Co-organizer (together with Sergio Lavandero) of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (April - May, 2016) and “Signalling in Biomedicine” (June-July, 2016). Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer” ICBM, Facultad de Medicina, U. de Chile. These two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas. This course represents a contribution of the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

13) Lecturer in post-graduate course entitled “Topics in Biomedical Research” organized by Miguel Concha (May 2016), at Facultad de Medicina, Universidad de Chile. Topic: “Cell migration, invasion and metastasis”

14) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell and Molecular Biology” (Sept - Dec, 2016). Coordinator of the section “Dynamics of Cytoplasm, Cytoskeleton, and cell migration”. Lecturer for the following topics; “Organization of the plasma membrane – microdomains - cell migration”. This course is taught to students primarily from the Facultad de Ciencias, Ciencias Químicas y Farmacéuticas, Farmacología and Medicine. This course represents a contribution of the FONDAP group ACCDiS/CEMC to inter-faculty post-graduate education at the Universidad de Chile.

15) Lecturer in post-graduate course entitled “Advanced Molecular Farmacology” organized by Guillermo Diaz (August 2016), at Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Topic: “signalling mechanisms in cancer, cell cycle, cell death”

16) Co-organizer (together with Alejandro Corvalan and Gareth Owen) of the first transversal course in Cancer in the framework of ACCDiS between the UC and PUC “Biomedical Oncology” (Sept. – Dec. 2016). Coordinator and lecturer for the following topics: “Molecular mechanimsms in cancer”, “Cell cycle”, “Cell death”

17) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by Lisette Leyton (Oct-Nov 2016), at Facultad de Medicina, Universidad de Chile.

18) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (Oct-Nov 2016), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

19) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by Lisette Leyton/AnaMaria Avalos (Oct-Nov 2016), at Facultad de Medicina, Universidad de Chile.

20) Co-organizer (together with Sergio Lavandero) of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (April - May, 2017) and “Signalling in Biomedicine” (June-July, 2016). Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer” ICBM, Facultad de Medicina, U. de Chile. These two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas. This course represents a contribution of the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

21) Lecturer in post-graduate course entitled “Advanced Molecular Farmacology” organized by Guillermo Diaz (August 2017), at Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Topic: “signalling mechanisms in cancer, cell cycle, cell death”. Tutor for three “tesillas” of students in the Farmacology PhD program (Renato Burgos, Carolina Schaefer, Karen Toledo).

22) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (May and Nov 2017), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

23) Co-organizer (together with Alejandro Corvalan and Gareth Owen) of the first transversal course in Cancer in the framework of ACCDiS between the UC and PUC “Biomedical Oncology” (Sept. – Dec. 2017). Coordinator and lecturer for the following topics: “Molecular mechanimsms in cancer”, “Cell cycle”, “Cell death”

24) Co-organizer (together with Sergio Lavandero) of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (April - May, 2018) and “Signalling in Biomedicine” (June-July, 2018). Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer” ICBM, Facultad de Medicina, U. de Chile. These two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas. This course represents a contribution of the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

25) Lecturer in post-graduate course entitled “Advanced Molecular Farmacology” organized by Juan Diego Maya (March-August 2018), at Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Topic: “Signalling mechanisms in cancer, cell cycle, cell death”. Tutor “tesillas” of students in the Farmacology PhD program (Pedro Jara). Tutor “Unidad” to learn basic lab skills (Sept 2018) for students in Farmacology (Pedro Novoa).

26) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (May and Nov 2018), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

27) Lecturer in post-graduate course entitled “Listening and Oral Communication” and “Oral Communication and Discussing papers in English” organized by Lisette Leyton (June and Oct 2018), at Facultad de Medicine, Universidad de Chile.

28) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell and Molecular Biology” (Aug - Nov, 2018). Coordinator of the section “Cell Signalling”. Lecturer for the following topics; “Organization of the eukaryotic cell, GPCRs, RTKs, nRTKs and other signalling mechanisms, plasma membrane – microdomains”. This course is taught to students primarily from the Facultad de Ciencias Químicas y Farmacéuticas and Medicine. This course represents a contribution of the anillo group NEMESIS/CEMC and the FONDAP group ACCDiS/CEMC to inter-faculty post-graduate education at the Universidad de Chile.

29) Co-organizer (together with Alejandro Corvalan and Gareth Owen) of the first transversal course in Cancer in the framework of ACCDiS between the UC and PUC “Biomedical Oncology” (Sept. – Dec. 2018). Coordinator and lecturer for the following topics: “Molecular mechanimsms in cancer”, “Cell cycle”, “Cell death”

30) Organizer of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (March - May, 2019), Novel Concepts in Signalling (May-June 2019) Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer”, “Exosomes”, “Lipid rafts and Caveolae”. ICBM, Facultad de Medicina, U. de Chile. The two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas and Faculty of Medicine. This course represents a contribution of the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

31) Lecturer in post-graduate course entitled “Advanced Molecular Pharmacology” organized by Juan Diego Maya (March-August 2019), at Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Topic: “Signalling mechanisms in cancer, cell cycle, cell death”.

32) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (May and Nov 2019), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

33) Lecturer in post-graduate course entitled “Listening and Oral Communication” and “Oral Communication and Discussing papers in English” organized by Lisette Leyton (June and Nov 2019), at Facultad de Medicine, Universidad de Chile.

34) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell Biology” (Aug - Nov, 2019). Coordinator of the section “Cell Signalling”. Lecturer for the following topics; “Organization of the eukaryotic cell, GPCRs, RTKs, nRTKs and other signalling mechanisms, plasma membrane – microdomains”. This course is taught to students primarily from the Facultad de Ciencias Químicas y Farmacéuticas and Medicine. This course represents a contribution of the anillo group NEMESIS/CEMC and the FONDAP group ACCDiS/CEMC to inter-faculty post-graduate education at the Universidad de Chile.

35) Co-organizer (together with Alejandro Corvalan and Gareth Owen) of the first transversal course in Cancer in the framework of ACCDiS between the UC and PUC “Biomedical Oncology” (Sept. – Dec. 2019). Coordinator and lecturer for the following topics: “Molecular mechanisms in cancer”, “Cell cycle”, “Cell death”

36) Organizer post-graduate curse of the PhD program in Biomedical Sciences of the Universidad de Talca “Analysis and discussion in English of scientific articles in the area of Signal Transduction” (April – December 2019). Coordinator and Lecturer.

37) Organizer of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (March - May, 2020), Novel Concepts in Signalling (May-June 2020) Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer”, “Exosomes”, “Lipid rafts and Caveolae”. ICBM, Facultad de Medicina, U. de Chile. The two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas and Faculty of Medicine. This course represents a contribution of the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

38) Lecturer in post-graduate course entitled “Advanced Molecular Pharmacology” organized by Jenny Fiedler (March-August 2020), at Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Topic: “Signalling mechanisms in cancer, cell cycle, cell death”.

39) Lecturer in post-graduate course entitled “Reading and Discussing papers in English” organized by AnaMaria Avalos (May and Nov 2020), at Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile.

40) Lecturer in post-graduate course entitled “Listening and Oral Communication” and “Oral Communication and Discussing papers in English” organized by Lisette Leyton (June and Nov 2020), at Facultad de Medicine, Universidad de Chile.

41) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell Biology” (Aug - Nov, 2020). Coordinator of the section “Cell Signalling”. Lecturer for the following topics; “Organization of the eukaryotic cell, GPCRs, RTKs, nRTKs and other signalling mechanisms, plasma membrane – microdomains”. This course is taught to students primarily from the Facultad de Ciencias Químicas y Farmacéuticas and Medicine. This course represents a contribution of the anillo group NEMESIS/CEMC and the FONDAP group ACCDiS/CEMC to inter-faculty post-graduate education at the Universidad de Chile.

42) Co-organizer (together with Alejandro Corvalan) of the first transversal course in Cancer in the framework of ACCDiS between the UC and PUC “Biomedical Oncology” (Sept. – Dec. 2020). Coordinator and lecturer for the following topics: “Molecular mechanisms in cancer”, “Cell cycle”, “Cell death”

43) Organizer of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (March - May, 2021), Novel Concepts in Signalling (May-June 2021) Lecturer for the following topics; “Ras-Raf-MAPK pathway”, “PKC- PI3K”, “Mechanisms underlying compartmentalisation of signal transduction molecules”, “Lipid second messengers”, “Protein Motifs mediating Lipid Interactions”, “Signalling in cell death”, “Signalling in Cancer”, “Exosomes”, “Lipid rafts and Caveolae”. ICBM, Facultad de Medicina, U. de Chile. The two modules are taught to students at the Facultad de Ciencias Químicas y Farmacéuticas and Faculty of Medicine. This course represents a contribution of the FONDAP group ACCDiS/CEMC to post-graduate education in four faculties of the Universidad de Chile.

44) Lecturer in post-graduate course entitled “Listening and Oral Communication” and “Oral Communication and Discussing papers in English” organized by Lisette Leyton (June and Nov 2021), at Facultad de Medicine, Universidad de Chile.

45) Lecturer in the post-graduate course for biochemists entitled: “Molecular basis of cell signaling” organized by Mauricio Baez and Sergio Lavandero. Topics: “Lipid second messengers”; “Post-translational protein modification by phosphorylation”; “Organization and Compartmentalization of molecules in signaling” March/April 2021

46) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell Biology” (Aug - Nov, 2021). Coordinator of the section “Cell Signalling”. Lecturer for the following topics; “Organization of the eukaryotic cell, GPCRs, RTKs, nRTKs and other signalling mechanisms, plasma membrane – microdomains”. This course is taught to students primarily from the Facultad de Ciencias Químicas y Farmacéuticas and Medicine. This course represents a contribution of CEMC and the FONDAP group ACCDiS to inter-faculty post-graduate education at the Universidad de Chile. Course cancelled due to lack of inscriptions.

47) Co-organizer (together with Alejandro Corvalan) of the first transversal course in Cancer in the framework of ACCDiS between the UC and PUC “Biomedical Oncology” (Sept. – Dec. 2021). Coordinator and lecturer for the following topics: “Molecular mechanisms in cancer”, “Cell cycle”, “Cell death” course cancelled due to lack of inscriptions.

48) Organizer of an interfaculty post-graduate Course, “Basic Concepts in Cell Signalling” (March - May, 2022), Novel Concepts in Signalling (May-June 2022) ICBM, Facultad de Medicina, U. de Chile. The course was cancelled due to the lack of inscriptions by students from the PhD program in Biomedical Sciences.
Instead several modules (kinases, phosphatases, proteases, lipid second messengers, compartmentalization ) were taught to students of the Facultad de Ciencias Químicas y Farmacéuticas in the PhD programs of Biochemistry and Pharmacology.

49) Lecturer in post-graduate course entitled “Listening and Oral Communication” and “Oral Communication and Discussing papers in English” organized by Lisette Leyton (June and Nov 2022), at Facultad de Medicine, Universidad de Chile.

50) Lecturer in the post-graduate course for biochemists entitled: “Molecular basis of cell signaling” organized by Mauricio Baez and Sergio Lavandero. Topics: “Lipid second messengers”; “Post-translational protein modification by phosphorylation”; “Organization and Compartmentalization of molecules in signaling” March/May 2022

51) Lecturer in the post-graduate course for pharmacologists entitled: “Advanced Molecular Pharmacology” organized by Jenny Fiedler. Topics: “Lipid second messengers”; “receptor and non-receptor tyrosine kinases”; “Phosphatases”; “Proteases” March/May 2022

52) Organizer post-graduate course of the PhD program in Biomedical Sciences of the Universidad de Talca “Analysis and discussion in English of scientific articles in the area of Signal Transduction” (April – December 2019). Lecturer.

53) Co-organizer (together with Vicente Torres and Mario Chiong) of an interfaculty post-graduate course of the University of Chile, “Advanced Cell Biology” (Aug - Nov, 2022). Coordinator of the section “Cell Signalling”. Lecturer for the following topics; “Organization of the eukaryotic cell, GPCRs, RTKs, nRTKs and other signalling mechanisms, plasma membrane – microdomains”. This course is taught to students primarily from the Facultad de Ciencias Químicas y Farmacéuticas and Medicine. This course represents a contribution of CEMC and the FONDAP group ACCDiS to inter-faculty post-graduate education at the Universidad de Chile. Course cancelled due to lack of inscriptions.

54) Lecturer in the post-graduate course for biochemists entitled: “Cell signaling in Biomedicine” organized by Mauricio Baez and Sergio Lavandero. Topics: “Cancer” September 2022.