Man

Mauricio Gabriel Henriquez Luna

Profesor asistente

Universidad de Chile / Facultad de Medicina

Santiago, Chile

Líneas de Investigación


Rol de los Receptores Purinérgicos en el control de tono de vasos pulmonares y bronquiolos, particularmente su participación en Hipertensión Arterial pulmonar, Síndrome de Distrés Respiratorio y últimamente en Enfermedad Pulmonar Obstructiva Crónica.

Educación

  •  TECNOLOGO MEDICO, UNIVERSIDAD DE CHILE. Chile, 1995
  •  BIOLOGÍA DE LA REPRODUCCIÓN, UNIVERSIDAD DE CHILE. Chile, 2001
  •  CIENCIAS BIOMÉDICAS, UNIVERSIDAD DE CHILE. Chile, 2005

Experiencia Académica

  •   PROFESOR ASISTENTE Full Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    SANTIAGO, Chile

    2009 - At present

  •   Research Associate Full Time

    TEXAS TECH UNIVERSITY

    HEALTH SCIENCES CENTER

    Lubbock, Tx, Estados Unidos

    2010 - 2011

  •   Postdoctoral Fellow Full Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    SANTIAGO, Chile

    2006 - 2008

  •   Research Assistant Part Time

    UNIVERSIDAD DE CHILE

    MEDICINA

    SANTIAGO, Chile

    1997 - 2005

Experiencia Profesional

  •   Profesor asistente Full Time

    Universidad de Chile / Facultad de Medicina

    Santiago, Chile

    2009 - At present

  •   Tecnólogo Médico Full Time

    Universidad de Chile / Hospital José Joaquín Aguirre

    Santiago, Chile

    1994 - 1997

  •   Asistente de Investigación Part Time

    Universidad de Chile / Instituto de Ciencias Biomédicas / Programa de Fisiología y Biofísica

    Santiago, Chile

    1997 - 2005


 

Article (19)

Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways

Mendez, Andrea; Rojas, Diego A.; Ponce, Carolina A; Bustamante, Rebeca; Beltran, Carol J.; Toledo, Jorge; Garcia-Angulo, Victor A.; Henriquez, Mauricio; Vargas, Sergio L.

Article ISI SCOPUS
PLOS ONE  (2019)

Cancer Imprints an Increased PARP-1 and p53-Dependent Resistance to Oxidative Stress on Lymphocytes of Patients That Later Develop Alzheimer's Disease.

Salech, Felipe; Ponce, Daniela; San Martín, Carol; Rogers, Nicole; Chacón, Carlos; Henríquez, Mauricio; Behrens, Maria Isabel.

Article
FRONTIERS IN NEUROSCIENCE  (2018)

Purinergic receptor stimulation induces calcium oscillations and smooth muscle contraction in small pulmonary veins.

Henriquez, Mauricio; Fonseca, Mauricio; Perez-Zoghbi, Jose

Article
JOURNAL OF PHYSIOLOGY-LONDON  (2018)

Vitamin D Increases A beta 140 Plasma Levels and Protects Lymphocytes from Oxidative Death in Mild Cognitive Impairment Patients

SanMartin, CD; Henriquez, M; Chacon, C; Ponce, DP; Salech, F; Rogers, NK; Behrens, MI

Article ISI SCOPUS
CURRENT ALZHEIMER RESEARCH  (2018)

PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD Patients

Salech, F; Ponce, DP; SanMartin, CD; Rogers, NK; Chacon, C; Henriquez, M; Behrens, MI

Article ISI SCOPUS
FRONTIERS IN AGING NEUROSCIENCE  (2017)

Increased Susceptibility to Oxidative Death of Lymphocytes from Alzheimer Patients Correlates with Dementia Severity

Ponce, DP; Salech, F; San Martin, CD; Silva M.; Xiong, C.; Roe, CM; Henríquez M; Quest, AF; Behrens, MI

Article ISI SCOPUS
CURRENT ALZHEIMER RESEARCH  (2014)

FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7)

Aguirre A.; Shoji, KF; Sáez JC; Henríquez M; Quest, AFG

Article ISI SCOPUS
Journal of Cellular Physiology  (2013)

Age-Dependent Increases in Apoptosis/Necrosis Ratios in Human Lymphocytes Exposed to Oxidative Stress

Behrens, MI; Silva M.; Schmied, A.; Salech, F; Manzur, H.; Rebolledo R.; Bull, R; Torres V.; Henríquez M; Quest, AFG

Article ISI SCOPUS
Journals of Gerontology - Series A Biological Sciences and Medical Sciences  (2011)

ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation

Henríquez M; Herrera-Molina, R; Valdivia, A; Alvarez A.; Kong M.; Muñoz, N.; Eisner V.; Jaimovich E.; Schneider, P.; Quest, AFG; Leyton, L

Article ISI SCOPUS
Journal of Cell Science  (2011)

Electrophysiological Characterization of Potassium Conductive Pathways in Trypanosoma cruzi

Jimenez, V; Henríquez M; Galanti N.; RIQUELME, G

Article ISI SCOPUS
Journal of Cellular Biochemistry  (2011)

Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells

Villena J.; Henríquez M; Torres V.; Moraga, F; Diaz-Elizondo, J; Arredondo, C; Chiong M.; Olea Azar C.; Stutzin A.; Lavandero S.; Quest, AFG

Article ISI SCOPUS
FREE RADICAL BIOLOGY AND MEDICINE  (2008)

Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane

Bernucci, L; Henríquez M; Díaz P; RIQUELME, G

Article ISI SCOPUS
PLACENTA  (2006)

Puroindoline-a and alpha 1-purothionin form ion channels in giant liposomes but exert different toxic actions on murine cells

Llanos P.; Henríquez M; Minic, J; Elmorjani, K; Marion, D; RIQUELME, G; Molgó J.; Benoit, E

Article ISI SCOPUS
FEBS JOURNAL  (2006)

Proteomic analysis of apical microvillous membranes of syncytiotrophoblast cells reveals a high degree of similarity with lipid rafts.

Paradela A., Bravo S.B., Henríquez M., Riquelme G., Gavilanes F., González-Ros J.M., and Albar J.P.

Article
J Proteome Res  (2005)

Isolation and purification of human placental plasma membranes from normal and pre-eclamptic pregnancies. A comparative study

Jimenez, V; Henríquez M; Llanos P.; RIQUELME, G

Article ISI SCOPUS
PLACENTA  (2004)

Neuronal and muscular alterations caused by two wheat endosperm proteins, puroindoline-a and alpha1-purothionin, are due to ion pore formation

Llanos P.; Henríquez M; Minic, J; Elmorjani, K; Marion, D; RIQUELME, G; Molgó J.; Benoit, E

Article ISI
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS  (2004)

17 beta-estradiol and tamoxifen regulate a maxi-chloride channel from human placenta

Henríquez M; RIQUELME, G

Article ISI SCOPUS
JOURNAL OF MEMBRANE BIOLOGY  (2003)

A low conductance, non-selective cation channel from human placenta

Llanos P.; Henríquez M; RIQUELME, G

Article ISI SCOPUS
PLACENTA  (2002)

Functional transplantation of chloride channels from the human syncytiotrophoblast microvillous membrane to Xenopus oocytes

Ivorra, I; Henríquez M; Lax P.; RIQUELME, G; Morales A.

Article ISI
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY  (2002)

Abstract (10)

Purinergic receptor stimulation induces Ca2+ oscillations and smooth muscle contraction in small pulmonary veins

Henríquez M; Perez-Zoghbi, J

Abstract ISI
FASEB JOURNAL  (2014)

Comparative total currents between apical syncytiotrophoblast membrane in normal and pre-eclamptic human placenta transplanted to Xenopus laevis oocytes.

Díaz P; Munoz, C; Cruz, C; Henríquez M; RIQUELME, G

Abstract ISI
PLACENTA  (2006)

Detergent-resistant membrane microdomains in apical membranes from human syncytiotrophoblast

Godoy, V; Henríquez M; RIQUELME, G

Abstract ISI
PLACENTA  (2006)

Maxi Chloride Channel is a candidate for apical ATP release in human placental syncytiotrophoblast

Henríquez M; RIQUELME, G

Abstract ISI
PLACENTA  (2006)

VDAC-1 as the molecular correlate of the maxi chloride channel from human placental syncytiotrophoblast

Henríquez M

Abstract ISI
PLACENTA  (2006)

Proteomic analysis of apical microvillous membranes of syncitiothrophoblast cells reveals a high degree of similarity with lipid rafts

Paradela A.; Bravo S.; Henríquez M; RIQUELME, G; Gavilanes F.; Gonzalez-Ros, J; Albar, J

Abstract ISI
MOLECULAR CELLULAR PROTEOMICS  (2005)

Regulation of human placental chloride channel by steroids hormones

Henríquez M

Abstract ISI
BIOPHYSICAL JOURNAL  (2001)

Non selective cation channels from human placenta.

RIQUELME, G; Llanos P.; Henríquez M

Abstract ISI
BIOPHYSICAL JOURNAL  (2000)

Non-selective cation channel in placental membranes

Llanos P.; Henríquez M; RIQUELME, G

Abstract ISI
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

Transplantation of chloride channels from human placenta to the membrane of Xenopus oocytes

Henríquez M; Ivorra, I; Lax P.; Morales A.; RIQUELME, G

Abstract ISI
JOURNAL OF PHYSIOLOGY-LONDON  (2000)

BookSection (1)

La puroindoline-a et l'alfa-1-purothionine: deux protéines de l’albumen de blé formatrices de pores ioniques

Llanos P., Henríquez M., Minic J., Elmorjani K., Marion D., Riquelme G., Molgó, J. and Benoit, E.

BookSection
 (2002)

Proyecto (7)

Red para el Estudio de Enfermedades Cardiopulmonares de Alta Letalidad (REECPAL)

Universidad de Chile (U-REDES-G_2018-35)

Proyecto
2018-2020
Inv. Principal

"Nueva terapia farmacológica para el tratamiento de sarcopenia y distrofias musculares. Prueba de concepto"

FONDEF (D16I10101)

Proyecto
2017-2018
Subdirector(a)

Determinants of lung injury induced by spontaneous breathing efforts during the transition from controlled ventilation to partial ventilatory support in ARDS patients

FONDECYT (1161510)

Proyecto
2016-2020
Coinvestigador(a)

CELLULAR SENESCENCE AND SENESCENCE-ASSOCIATED SECRETION PHENOTYPE (SASP) INVOLVEMENT IN THE INVERSE ASSOCIATION BETWEEN ALZHEIMER DISEASE AND CANCER

FONDECYT (1151297)

Proyecto
2015-2019
Coinvestigador(a)

SMALL INTRAPULMONARY VESSELS IN PULMONARY HYPERTENSION=> PURINERGIC CONTROL OF PULMONARY VASCULAR TONE

FONDECYT (1140468)

Proyecto
2014-2017
Inv. Responsable

Nuevas alternativas en el efecto de TRH en la maduración pulmonar fetal

OCIC del Hospital Clínico de la Universidad de Chile

Proyecto
1996-1997
Coinvestigador(a)

Automatización de una técnica de TSH neonatal para el diagnóstico precoz de hipotiroidismo congénitol

Boehringer Mannheim

Proyecto
1994-1995
Coinvestigador(a)

Review (1)

Cell death by necrosis, a regulated way to go

Henríquez M; Armisen, R; Stutzin A.; Quest, AFG

Review ISI
CURRENT MOLECULAR MEDICINE  (2008)

28
Mauricio Henriquez

Profesor asistente

PROGRAMA DE FISIOLOGÍA Y BIOFíSICA

Universidad de Chile / Facultad de Medicina

Santiago, Chile

6
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

4
Felipe Salech

Academic

Medicine

Universidad de Chile / Facultad de Medicina

Santiago, Chile

4
Maria Behrens

Profesor Titular

Neurología y Neurocirugía, y de Neurociencia

Hospital Clínico Universidad de Chile

Santiago, Chile

4
Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

2
JUAN VILLENA

FULL PROFESSOR

ANATOMY

FACULTA DE MEDICINA. UNIVERSIDAD DE VALPARAISO

VIÑA DEL MAR, Chile

2
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
Mónica Silva

Lab Manager

Fisiología y Biofísica

Universidad de Chile

Santiago, Chile

2
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

2
Carlos Chacon

Asistente de Investigación

Impact

Universidad de Los Andes

Santiago, Chile

2
Nicole Rogers

Instructora

Universidad de Chile

Santiago, Chile

1
Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Paula Díaz

Coordinadora de Investigación y Postgrado

Facultad de Salud

Universidad Santo Tomás

Santiago, Chile

1
Rodrigo Herrera

Group Leader (staff member)

Combinatorial NeuroImaging Core Facility

Leibniz Institute for Neurobiology

Magdeburg, Alemania

1
Daniela Ponce

Coordinadora de investigación

Universidad de Chile

Santiago, Chile

1
Carolina Ponce

Lab Manager Lab Infecciones Rspiratorias

Microbiología Y MIcología

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Patricia Diaz

Academic

University of Connecticut Health Center

Farmington, CT, Estados Unidos

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

1
Andrea Méndez

Académico Disciplinar Investigador

Facultad de Salud y Ciencias Sociales

Universidad de Las Américas

Santiago, Chile

1
claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

1
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Diego Rojas

Profesor Ayudante

Instituto de Ciencias Biomédicas (ICB)

Universidad Autónoma de Chile

Santiago, Chile

1
Sergio Vargas

Investigador Académico

Universidad de Chile

Santiago, Chile

1
Jorge Toledo

Investigador

Departamento de Anatomia y Biologia del Desarrollo

Universidad de Chile; Biomedical Neuroscience Institute (BNI)

Santiago, Chile

1
Hachi Manzur

Neurólogo de Adultos

Red de Salud UC Christus

Santiago, Chile

1
Valeria Godoy

Coordinadora de Programas

Centro Nacional de Conservación y Restauración

Santiago, Chile

1
Rolando Rebolledo

Cirujano

Servicio de Cirugía

Hospital Dr. Sótero del Río

Santiago, Chile