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Sergio Luis Vargas Munita

Investigador Académico

Universidad de Chile

Santiago, Chile

Natural history, molecular epidemiology, pathology and imunopathogenesis of Pneumocystis infection in human and animal models. Clinical Trials in Pulmonary Infections

Especialista en Pediatría, UNIVERSIDAD DE CHILE. Chile, 1986
Medico Cirujano, UNIVERSIDAD DE CHILE. Chile, 1979
Post Doctoral Fellowship Infectious Diseases (5 years), St Jude Children´s Research Hospital. Estados Unidos, 1994

Academico Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

1995 - At present
Profesor Titular Full Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2011 - At present

Pediatra, Jefe de Infectología y Neonatología Full Time

Hospital San Pablo, Coquimbo, IV Region.

Coquimbo, Chile

1982 - 1985
Instructor de Pediatría Part Time

Centro de Diagnóstico Universidad Catolica de Chile

Santiago, Chile

1986 - 1989
Post Doctoral Fellow Full Time

Department of Infectious Diseases, St Jude Children´s Research Hospital

Memphis, TN, Estados Unidos

1989 - 1994
Académico Full Time

Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile

Santiago, Chile

1995 - At present
Director Programa de Microbiología y Micología Instituto de Ciencias Biomédicas Full Time

Universidad de Chile

Santiago, Chile

2012 - 2014
Miembro Part Time

Comité de Etica, Servicio de Salud Metropolitano Norte

Santiago, Chile

2005 - 2010

Tesis de Doctorado o Especialidad Médica
Dr Patricio Madrid Soto, Tesis de Especialidad Patología 2004
Facultad de Medicina
Pontificia Universidad Católica de Chile

Tesis de Doctorado en Ciencias
Magali Chabé, PhD 2005
University of Lille, Lille, France

Tesis de Doctorado en Farmacología
Pablo Andrés Iturra Montecinos, PhD 2018
Facultad de Ciencias Químicas y Farmacéuticas
Universidad de Chile

Tesis de Doctorado en Farmacología
Andrea Méndez Gálvez, PhD 2019
Facultad de Ciencias Químicas y Farmacéuticas
Universidad de Chile

Tesis de Doctorado en Farmacología
Francisco Pérez Blanco, PhD 2019
Facultad de Ciencias Químicas y Farmacéuticas
Universidad de Chile

Tesis de Magister en Patología Veterinaria
Catherine Sánchez Núñez MSc 2002
Facultad de Ciencias Veterinarias y Pecuarias,
Universidad de Chile

Tesis de Magister en Microbiología
Carolina Ponce Olmos MSc 2005
ICBM, Facultad de Medicina
Universidad de Chile

Tesis de Magister en Microbiología
Paula Bonilla Zamudio MSc 2013
ICBM, Facultad de Medicina
Universidad de Chile

Tesis de Magister en Microbiología
Jaime Astorga Saavedra MSc 2013
ICBM, Facultad de Medicina
Universidad de Chile

Tesis de Magister en Farmacología
Andrea Méndez Gálvez MSc 2015
ICBM, Facultad de Medicina
Universidad de Chile

Tesis de Licenciatura: 10 alumnos.

Conferencias o Seminarios invitados

2020 Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile. “De la pneumonia intraepidémica del SIDA a infección pandémica subclínica”.
https://www.icbm.cl/seminarios-icbm/

2018 Universidad Peruana Cayetano Heredia, Lima, Perú. Formas emergentes de la infección por Pneumocystis mas allá del SIDA y del paciente inmunocomprometido.

2018 International Forum on Medical Parasitology. October 26, Wroclaw, Poland. Lecture: Pneumocystis: Changing views of an atypical fungus in the general population

2018 Invited Professorship: October 24-29. Medical University of Wroclaw, Wroclaw, Poland.

2018 ISHAM (International Society for Human and Animal Mycology) June - July, Amsterdam, The Neatherlands. Round Table presentation: Is Pneumocystis a pathogen for the immunocompetent infant?

2017 Fisabio, University of Valencia, Valencia, Spain: Pneumocystis in infants: a potential public health issue. https://www.youtube.com/watch?v=EXZeWO6wR94

2017 CYTED Lisbon, Portugal: Principal Investigator Progress report for the ERANetLAC European Union Project

2016 University of Laussane, Laussane Switzerland: Pneumocystis in infants.

2016 Instituto de Biomedicina de Sevilla. Congreso Prevention of Infectious Diseases and well-being.

2015 ISHAM (International Society for Human and Animal Mycology) Melbourne Australia: Pneumocystis epidemiology: Colonization versus Infection.

2014 IWOP (International Workshop on Opportunistic Protists) Seville, Spain: Pneumocystis in infants

Best Poster Award

St Jude Children´s Research Hospital

Estados Unidos, 2019

Premio a Poster Científico Destacado
Fellow IDSA

Infectious Diseases Society of America

Estados Unidos, 2005

Fellow IDSA
Beca Presidente de la República

MINISTERIO DE PLANIFICACION Y COOPERACION

Chile, 1989

Financiamiento para los 3 primeros años de Post-doctoral Fellow en el Departamento de Infectología, St Jude Children´s Research Hospital, Memphis, TN, EEUU.
Visiting Professor

UNIVERSITY OF WROCLAW

Polonia, 2018

Visiting Professor Medical University of Wroclaw, Wroclaw, Poland. Diploma and award.
Research and Innovation Disctinction

University of Chile

Chile, 2021

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Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants Kampmann B, Madhi SA, Munjal I, Simões EAF, Pahud BA, Llapur C, Baker J, Pérez Marc G, Radley D, Shittu E, Glanternik J, Snaggs H, Baber J, Zachariah P, Barnabas SL, Fausett M, Adam T, Perreras N, Van Houten MA, Kantele A, Huang LM, Bont LJ, Otsuki T, Var Article NEW ENGLAND JOURNAL OF MEDICINE (2023)
Pneumocystis Exacerbates Inflammation and Mucus Hypersecretion in a Murine, Elastase-Induced-COPD Model by Diego A. Rojas Diego A. Rojas, Carolina A. Ponce, Adriel Bustos,Vicente Cortés, Daniela Olivares and Sergio L. Vargas Article Journal of Fungi (2023)
A Real Time PCR assay for detection of low Pneumocystis jirovecii levels. Ruiz-Ruiz, Susana; Ponce, Carolina A; Pesantes, Nicole; Bustamante, Rebeca; Gatti, Gianna; San Martin, Viviana; Gutierrez, Mireya; Borquez, Pamela; Vargas, Sergio L; Magne, Fabien; Calderon, Enrique; Perez-Brocal, Vicente; Moya, Andres Article FRONTIERS IN MICROBIOLOGY (2022)
Sero-epidemiology of Pneumocystis infection among infants, children, and adults in Chile Miller, Robert; Daly, Kieran; Walzer, Peter; Ulloa, Ana V; Ponce, Carolina A; Vargas, Sergio Luis Article Journal of Fungi (2022)
Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine Falsey, A. R.; Sobieszczyk, M. E.; Hirsch, I; Sproule, S.; Robb, M. L.; Corey, L.; Neuzil, K. M.; Hahn, W.; Hunt, J.; Mulligan, M. J.; McEvoy, C.; DeJesus, E.; Hassman, M.; Little, S. J.; Pahud, B. A.; Durbin, A.; Pickrell, P.; Daar, E. S.; Bush, L.; Solis, J.; Carr, Q. O.; Oyedele, T.; Buchbinder, S.; Cowden, J.; Vargas, S. L.; Benavides, A. G.; Call, R.; Keefer, M. C.; Kirkpatrick, B. D.; Pullman, J.; Tong, T.; Isaacs, M. B.; Benkeser, D.; Janes, H. E.; Nason, M. C.; Green, J. A.; Kelly, E. J.; Maaske, J.; Mueller, N.; Shoemaker, K.; Takas, T.; Marshall, R. P.; Pangalos, M. N.; Villafana, T.; Gonzalez-Lopez, A.; AstraZeneca AZD1222 Clinical Study Article ISI NEW ENGLAND JOURNAL OF MEDICINE (2021)
Pneumocystis jirovecii colonization in preterm newborns with respiratory distress syndrome. Szyd?owicz M, Królak-Olejnik B, Vargas SL, Zaj?czkowska ?, Paluszy?ska D, Szczygie? A, Matos O, Hendrich AB, Kicia M. Article ISI, Scopus, Pubmed JOURNAL OF INFECTIOUS DISEASES (2021)
Pneumocystis primary infection in non-immunosuppressed infants in Lima, Peru Ochoa, Theresa J.; Beatriz Bustamante; Coralith García; Edgar Neyra; Mendoza, Karina; Calderon, Enrique J; Le Gal, Solène; Miller, Robert F.; Carolina A Ponce; Nevez, Gilles.; Vargas, Sergio L Article JOURNAL OF MEDICAL MYCOLOGY (2021)
Consensus Multilocus Sequence Typing Scheme for Pneumocystis jirovecii Pasic, Lana; Goterris, Lidia; Guerrero-Murillo, Mercedes; Irinyi, Laszlo; Kan, Alex; Ponce, Carolina A.; Vargas, Sergio L.; Teresa Martin-Gomez, M.; Meyer, Wieland Article ISI JOURNAL OF FUNGI (2020)
Optimized DNA extraction and purification method for characterization of bacterial and fungal communities in lung tissue samples Perez-Brocal, Vicente; Magne, Fabien; Ruiz-Ruiz, Susana; Ponce, Carolina A.; Bustamante, Rebeca; San Martin, Viviana; Gutierrez, Mireya; Gatti, Gianna; Vargas, Sergio L.; Moya, Andres Article ISI SCIENTIFIC REPORTS (2020)
Pneumocystis jirovecii colonisation in pregnant women and newborns in Lima, Peru [Colonización por Pneumocystis jirovecii en mujeres gestantes y recién nacidos en Lima, Perú] Garcia C.; Ochoa T.; Neyra E.; Bustamante B.; Ponce C.; Calderon E.J.; Vargas, S.L. Article SCOPUS Revista Iberoamericana de Micologia (2020)
Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants Griffin, M. Pamela; Yuan, Yuan; Takas, Therese; Domachowske, Joseph B.; Madhi, Shabir A.; Manzoni, Paolo; Simoes, Eric A. F.; Esser, Mark T.; Khan, Anis A.; Dubovsky, Filip; Villafana, Tonya; DeVincenzo, John P.; Nirsevimab Study Grp Article ISI NEW ENGLAND JOURNAL OF MEDICINE (2020)
Increase in secreted airway mucins and partial Muc5b STAT6/FoxA2 regulation during Pneumocystis primary infection Rojas, DA; Iturra, PA; Mendez, A.; Ponce, CA; Bustamante, R; Gallon, M; Borquez, P; Vargas, SL Article ISI SCOPUS SCIENTIFIC REPORTS (2019)
New DNA Extraction Method for the Detection of Pneumocystis in Lung Tissue Samples of Colonized Individuals Ruiz-Ruiz, Susana; A Ponce, Carolina; Pesantes, Nicole; Bustamante, Rebeca; Gatti, Gianna; San Martin, Viviana; Gutierrez, Mireya; Izquierdo, Mariana; L Vargas, Sergio; Magne, Fabien; Pérez-Brocal, Vicente Article OBM Genetics (2019)
Niflumic Acid Reverses Airway Mucus Excess and Improves Survival in the Rat Model of Steroid-Induced Pneumocystis Pneumonia PÃ©rez F.J.; Iturra P.A.; Ponce, C.A.; Magne F.; Garcia-Angulo V.; Vargas, S.L. Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2019)
Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways Mendez, Andrea; Rojas, Diego A.; Ponce, Carolina A; Bustamante, Rebeca; Beltran, Carol J.; Toledo, Jorge; Garcia-Angulo, Victor A.; Henriquez, Mauricio; Vargas, Sergio L. Article ISI SCOPUS PLOS ONE (2019)
Progression of Type 2 Helper T Cell-Type Inflammation and Airway Remodeling in a Rodent Model of Naturally Acquired Subclinical Primary Pneumocystis Infection Iturra, PA; Rojas, DA; Perez, FJ; Mendez, A; Ponce, CA; Bonilla, P; Bustamante, R; Rodriguez, H; Beltran, CJ; Vargas, SL Article ISI SCOPUS AMERICAN JOURNAL OF PATHOLOGY (2018)
Early Acquisition of Pneumocystis jirovecii Colonization and Potential Association With Respiratory Distress Syndrome in Preterm Newborn Infants Rojas, P; Friaza, V; Garcia, E; de la Horra, C; Vargas, SL; Calderon, EJ; Pavon, A Article ISI SCOPUS Clinical Infectious Diseases (2017)
High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy Ponce C.A.; Chabé M.; George C.; Cárdenas A.; Durán L.; Guerrero J.; Bustamante R.; Matos O.; Huang L.; Miller R.F.; Vargas S.L. Article ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Mepolizumab for Eosinophilic COPD Pavord, Ian D; Chanez, P.; Criner, G.J.; Bradford, ES.; and participant investigators listed in supplemental information (Vargas SL and 167 others) Article ISI, SCOPUS NEW ENGLAND JOURNAL OF MEDICINE (2017)
Diagnosis of the primary infection by pneumocystis in autopsy specimens from two infants using lung impression smears (touch preps) Ponce, C.A.; Bustamante R.I.; Gallo, M; Vargas, S.L. Article SCOPUS Medical Mycology Case Reports (2014)
Fungal colonization with Pneumocystis correlates to increasing chloride channel accessory 1 (hCLCA1) suggesting a pathway for up-regulation of airway mucus responses, in infant lungs Pérez F.J.; Ponce, C.A.; Rojas, D.A; Iturra P.A.; Bustamante R.I.; Gallo, M; Hananias, K; Vargas, S.L. Article SCOPUS Results in Immunology (2014)
Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma Ortega, Hector G.; Liu, Mark C.; Pavord, Ian D.; Brusselle, Guy G.; FitzGerald, J. Mark; Chetta, Alfredo; Humbert, Marc; Katz, Lynn E.; Keene, Oliver N.; Yancey, Steven W.; Chanez, Pascal; MENSA Investigators Article ISI NEW ENGLAND JOURNAL OF MEDICINE (2014)
Ventilator associated pneumonia after elective cardiac surgery caused by Pneumocystis jirovecii Tobar, Eduardo; Silva, Francisco; Zamorano, A.; Cifuentes, M.; Miller, Robert F.; Vargas, S.L. Article Grand Rounds (2014)
Near-Universal Prevalence of Pneumocystis and Associated Increase in Mucus in the Lungs of Infants With Sudden Unexpected Death Vargas, SL; Ponce, CA; Gallo, M; Pérez F.; Astorga, JF; Bustamante, R; Chabe M; Durand-Joly, I; Iturra, P; Miller RF; Aliouat, E; Dei-Cas, E Article ISI SCOPUS Clinical Infectious Diseases (2013)
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre double-blind, placebo controlled trial. Pavor, Ian D.; Korn, Stephanie; Howarth, Peter; and the DREAM multicentric study investigators (SL Vargas and others lised in supplemental information) Article ISI SCOPUS The Lancet Regional Health - Western Pacific (2012)
Pneumocystis Colonization in Older Adults and Diagnostic Yield of Single versus Paired Noninvasive Respiratory Sampling Vargas, SL; Pizarro, P.; Lopez-Vieyra, M; Neira-Aviles, P; Bustamante, R; Ponce, CA Article ISI SCOPUS Clinical Infectious Diseases (2010)
Pneumocystis Colonization Is Highly Prevalent in the Autopsied Lungs of the General Population Ponce, CA; Gallo, M; Bustamante, R; Vargas, SL Article ISI SCOPUS Clinical Infectious Diseases (2010)
Seroepidemiological study of Pneumocystis jirovecii infection in healthy infants in Chile using recombinant fragments of the P. jirovecii major surface glycoprotein Djawe, K; Daly, KR; Vargas, SL; Santolaya, ME; Ponce, CA; Bustamante, R; Koch J.; Levin L.; Walzer, PD Article ISI SCOPUS International Journal of Infectious Diseases (2010)
Exploring transplacental transmission of Pneumocystis oryctolagi in first-time pregnant and multiparous rabbit does Sanchez, CA; Chabe M; Aliouat, EM; Durand-Joly, I; Gantois, N; Conseil, V; López C.; Duriez, T; Dei-Cas, E; Vargas, SL Article ISI SCOPUS MEDICAL MYCOLOGY (2007)
Pneumocystis is not a direct cause of sudden infant death syndrome Vargas, SL; Ponce, CA; Galvez, P; Ibarra, C; Haas, EA; Chadwick, AE; Krous, HF Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2007)
Sudden Infant Death Syndrome and activating GNAS1 gene mutations Roman, Rossana; Lopez, P; Johnson, Maria Cecilia; Boric M.A.; Gallo, Myriam Del Carmen; Ponce, Carolina A; Vargas, Sergio Luis; Codner, Ethel; Cassorla, Fernando Article FETAL AND PEDIATRIC PATHOLOGY (2007)
A Randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated otitis media. Arguedas, A.; Emparanza, P; Schwartz, R.; and collaborative investigators (Vargas SL and others) Article ISI PEDIATRIC INFECTIOUS DISEASE JOURNAL (2005)
Detection of Pneumocystis carinii f. sp hominis and viruses in presumably immunocompetent infants who died in the hospital or in the community Vargas, SL; Ponce, CA; Luchsinger, V.; Silva C.; Gallo, M; Lopez R.; Belletti, J; Velozo, L; Ávila R.; Palomino, MA; Benveniste S.; AVENDANO, LF Article ISI SCOPUS JOURNAL OF INFECTIOUS DISEASES (2005)
Molecular typing of Pneumocystis jirovecii found in formain-fixed paraffin-embedded lung tissue sections from sudden infant death victims Chabe M; Aliouat E.M.; Follet-Dumoulin, A; Recourt, C; Camus, D; Dei-Cas, E; Durand-Joly, I; Vargas, S.L.; Eyzaguirre, I; Creusy, C; Fleurisse, L Article SCOPUS MICROBIOLOGY-SGM (2004)
Molecular typing of Pneumocystis jirovecii found in formalin-fixed paraffin-embedded lung tissue sections from sudden infant death victims Chabe M; Vargas, SL; Eyzaguirre, I; Aliouat, EM; Follet-Dumoulin, A; Creusy, C; Fleurisse, L; Recourt, C; Camus, D; Dei-Cas, E; Durand-Joly, I Article ISI MICROBIOLOGY-SGM (2004)
Study design questions in treatment of children with acute otitis media. Arrieta, Antonio; Arguedas, A.; Block, Stanley.; Vargas, S.L.; Erhart, W.A.; De Caprariis P.J. Article ISI ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Efficacy of single-dose azithromycin in treatment of acute otitis media in children after a baseline tympanocentesis Dunne, MW; Khurana, C; Mohs, AA; Rodríguez A.; Arrieta, A.; McLinn, S; Krogstad, JA; Blatter, M; Schwartz, R; Vargas, SL; Emparanza, P; Fernández P.; Gooch, WM; Aspin, M; Podgore, J; Roine, I; Blumer, JL; Ehrlich, GD; Chow, J Article ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media Arrieta, A.; Arguedas, A.; Fernández P.; Block, SL; Emperanza, P; Vargas, SL; Erhardt, WA; de Caprariis, PJ; Rothermel, CD Article ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Itraconazole or allopurinol in the treatment of chronic American trypanosomiasis: the regression and prevention of electrocardiographic abnormalities during 9 years of follow-up Apt, W; Arribada, A; Zulantay I.; Sánchez G; Vargas, SL; Rodriguez J. Article ISI SCOPUS Annals of Tropical Medicine and Parasitology (2003)
Pregnancy and asymptomatic carriage of Pneumocystis jiroveci Vargas, SL; Ponce, CA; Sanchez, CA; Ulloa, AV; Bustamante, R; Juarez, G Article ISI EMERGING INFECTIOUS DISEASES (2003)
Quinolone treatment for pediatric bacterial meningitis: a comparative study of trovafloxacin and ceftriaxone with or without vancomycin Saez-Llorens, X; McCoig, C; Feris, JM; Vargas, SL; Klugman, KP; Hussey, GD; Frenck, RW; Falleiros-Carvalho, LH; Arguedas, AG; Bradley, J; Arrieta, AC; Wald, ER; Pancorbo, S; McCracken, GH; Trovan Meningitis Study Grp Article ISI PEDIATRIC INFECTIOUS DISEASE JOURNAL (2002)
Distribution of Pneumocystis carinii f. sp. hominis types in the lung of a child dying of Pneumocystis pneumonia Ambrose, HE; Ponce, CA; WAKEFIELD, AE; Miller RF; Vargas, SL Article ISI CLINICAL INFECTIOUS DISEASES (2001)
Identification of Pneumocystis carinii in the lungs of infants dying of sudden infant death syndrome Morgan, DJ; Vargas, SL; Reyes-Mugica, M; Walterspiel, JN; Carver, W; Gigliotti, F Article ISI SCOPUS PEDIATRIC INFECTIOUS DISEASE JOURNAL (2001)
Search for primary infection by Pneumocystis carinii in a cohort of normal, healthy infants Vargas, SL; HUGHES, WT; Santolaya, ME; Ulloa, AV; Ponce, CA; Cabrera, CE; Cumsille F.; Gigliotti, F Article ISI SCOPUS CLINICAL INFECTIOUS DISEASES (2001)
A randomized, double-blind trial comparing azithromycin and clarithromycin in the treatment of disseminated Mycobacterium avium infection in patients with human immunodeficiency virus Dunne, M.; Fessel, J.; Kumar, P.; Dickenson, G.; Keiser, P.; Boulos, M.; Mogyros, M.; White Jr. A.C.; Cahn, P.; O'Connor, M.; Lewi, D.; Green, S.; Tilles, J.; Hicks, C.; Bissett, J.; Schneider, M. M.; Benner, R.; Collaborative investigators (Vargas S and others) Article CLINICAL INFECTIOUS DISEASES (2000)
Candidal meningitis in children with cancer McCullers, JA; Vargas, SL; Flynn, PM; Razzouk, BI; Shenep, JL Article ISI CLINICAL INFECTIOUS DISEASES (2000)
Severe apnea: an early sign of Pneumocystis carinii pneumonia in an HIV-negative infant Garcia, Claudia A.; Delpiano, Luis; Prado, Francisco; Ponce, Carolina A; Amaya, Marcela.; Vargas, Sergio L. Article REVISTA MEDICA DE CHILE (2000)
Transmission of Pneumocystis carinii disease from immunocompetent contacts of infected hosts to susceptible hosts Dumoulin, A; Mazars, E; Seguy, N; Gargallo-Viola D.; Vargas S.; Cailliez, JC; Aliouat, EM; WAKEFIELD, AE; Dei-Cas, E Article ISI SCOPUS EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY INFECTIOUS DISEASES (2000)
Transmission of Pneumocystis carinii DNA from a patient with P-carinii pneumonia to immunocompetent contact health care workers Vargas, SL; Ponce, CA; Gigliotti, F; Ulloa, AV; Prieto, S; Munoz, MP; HUGHES, WT Article ISI JOURNAL OF CLINICAL MICROBIOLOGY (2000)
Association of primary Pneumocystis carinii infection and sudden infant death syndrome Vargas, SL; Ponce, CA; HUGHES, WT; WAKEFIELD, AE; Weitz, JC; Donoso, S; Ulloa, AV; Madrid, P; Gould, S; LATORRE, JJ; Avila, R; Benveniste, S; Gallo, M; Belletti, J; Lopez, R Article ISI CLINICAL INFECTIOUS DISEASES (1999)
Current status and future challenges for the development of medical mycology in Chile: A local perspective. Thompson, L.; Vargas, S Article INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (1997)
Meningitis por Streptococcus pneumoniae resistente a penicilina y cefalosporina Avilés, Carmen L; Delpiano, Luis; Vargas, Sergio; Orellana, Ricardo Article REVISTA CHILENA DE INFECTOLOGIA (1997)
Oral steroids in the induction of experimental Pneumocystis carinii pneumonia Rudolph, Jorge.; Vargas, Sergio Article PARASITOLOGIA AL DIA (1996)
Search for Extrapulmonary Pneumocystis Carinii in an Animal Model Oz, H.; Hughes, W.T.; Vargas, S.L. Article ISI JOURNAL OF PARASITOLOGY (1996)
Sensibilidad de Estafilococcus aureus al ingreso y después de tres dias de hospitalización. Madrid, Patr; HERING A, ENRIQUE; Kagi, M; Diaz, J.M.; Molina, P.; Delgado C.; Droguett, E.; Vargas, Sergio Article Revista del Hospital Luis Calvo Mackenna (1996)
LIMITED PERSISTENCE IN AND SUBSEQUENT ELIMINATION OF PNEUMOCYSTIS-CARINII FROM THE LUNGS AFTER PNEUMOCYSTIS-CARINII PNEUMONIA VARGAS, SL; HUGHES, WT; WAKEFIELD, AE; OZ, HS Article ISI JOURNAL OF INFECTIOUS DISEASES (1995)
Uso de Anfotericina B en pacientes pediátricos Vargas, Sergio Article Acta pediátrica costarricence (1995)
CAVITARY LUNG LESIONS IN AN IMMUNOSUPPRESSED CHILD WINERMURAM, HT; VARGAS, S; SLOBOD, K Article ISI CHEST (1994)
Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer Vargas, Sergio L.; Shenep, Jerry L.; Flynn, Patricia M.; Pui, Ching-Hon.; Santana, Victor.; Hughes, Walter T. Article JOURNAL OF PEDIATRICS (1993)
Modulating effect of dietary carbohydrate supplementation on Candida albicans colonization and invasion in a neutropenic mouse model Vargas, Sergio L.; Patrick, Christian C.; Ayers, Gregory D.; Hughes, Walter T. Article ISI, SCOPUS INFECTION AND IMMUNITY (1993)
Prophylaxis of Pneumocystis pneumonia (Review) Vargas, Sergio L. Article Clinical Advances in Fungal Infections (1993)
ASPERGILLUS IN PEPPER VARGAS, S; HUGHES, WT; GIANNINI, MA Article ISI LANCET (1990)
Differences in the antibiotic sensitivity pattern of Coagulase Negative Staphylococci strains from ambulatory patients vs those isolated from inpatients Vargas, Sergio; FRANCISCO MONTIEL A. Article Revista Chilena de Infectología (1989)
Amebic disentery in a newborn. Vargas, Sergio; Grez, Lionel Article PARASITOLOGIA AL DIA (1986)
Kawasaki Disease (First Chilean cases) Herrera, Patricio; Oroz, Julia; Vargas, S. Article Pediatría (Hospital Roberto del Rio) (1983)
Rotavirus and acute diarrhea in infancy: comparison of hospitalized and outpatient cases. Avendaño, LF; Calderon, A.; Vargas, Sergio Article REVISTA MEDICA DE CHILE (1981)
Detection of rotavirus in hospitalized and ambulatory infants with acute diarrhea in Santiago de Chile Calderon Marin, A.; Avendaño, L.F.; Varas, X.; Vargas Munita, S. Article BOLETIN MEDICO DEL HOSPITAL INFANTIL DE MEXICO
Multicenter study of birth weight in Chile Vargas, N.; Thomas, E.; Mendez, C.; Diaz, C.; Vargas, S.; Dazzarola, P.; Melo, W.; Pulido, N.; Flores, G.; Montt, J. Article REVISTA MEDICA DE CHILE


Neumocystosis Vargas, Sergio L BookSection (2013)
Pneumocystis pneumonia Vargas, Sergio L; Kunzelmann, Karl BookSection Book chapter (2008)
Infectious Erythema and Human Parvovirus Vargas, S.; Fanta, E.; Meneguello, J., Fanta, E., Paris, E., Rosselot, J. BookSection (1990)


Pneumocystis primary infection in infancy: Additional French data and review of the literature Nevez G.; Guillaud-Saumur T.; Cros P.; Papon N.; Vallet S.; Quinio D.; Minoui-Tran A.; PilorgÃ© L.; De Parscau L.; Sizun J.; Ochoa T.J.; Bustamante B.; Ponce C.; Vargas, S.L.; Le Gal S. ConferencePaper ISI SCOPUS MEDICAL MYCOLOGY (2020)
Recent advances and future directions in Pneumocystis pneumonia Huang, Laurence; Morris, Alison; Limper, Andrew H.; Workshop participants (Vargas, S. and others); Huang, L. ConferencePaper (2006)


Pneumocystis Is Still Involved in Nonimmunosuppressed Preterm Infants in Europe Reply Rojas, P; Friaza, V; Garcia, E; de la Horra, C; Vargas, SL; Calderon, EJ; Pavon, A Letter ISI CLINICAL INFECTIOUS DISEASES (2018)


Use of polyols in combating yeast infection and polyol preparations for said use Sergio Vargas Munita Patent (2002)
New method for recognition of Pneumocystis epitopes Moya Simarro, Andres; Vargas Munita, Sergio; Ruiz Ruiz, Susana Patent ABG REf P18784ES00


Role of the commensal microbiota in lung mucus production Magne, Fabien; Vargas, Sergio Proyecto (2019)
Primary Infection by Pneumocystis in infants: A silent threat to public health Vargas, Sergio L; Calderon, Enrique Proyecto (2015)
Elucidation of Pneumocystis-induced pathology and sequels in murine models, and evaluation of selected markers of lung damage in autopsied infant lungs Vargas, Sergio L; Ponce, Carolina A Proyecto (2014)
Rol de FoxA2 en la remodelación y respuesta secretora del epitelio respiratorio inducido por la infección de Pneumocystis carinii Rojas Soto, Diego; Sponsor Proyecto (2013)
Red Iberoamericana sobre Pneumocystosis Calderon, Enrique J; Vargas, Sergio Proyecto (2012)
Characterization of the mucus-secreting response to Pneumocystis by the respiratory epithelium; a potential co-factor for increased severity of respiratory disease in the immunocompetent host Vargas, Sergio L; Ponce, Carolina A Proyecto (2010)
Emerging forms of Pneumocystis carinii infection and their epidemiological impact in the general population Vargas Munita, Sergio Luis; Ponce Olmos, Carolina A Proyecto (2006)
Primary infection by Pneumocystis in Children Vargas Munita, Sergio Luis; Dei-Cas, E Proyecto Proyecto ECOS-CONICYT (2005)
Development of the natural infection rabbit animal model for evaluation of different aspects of the primary infection by Pneumocystis carinii Vargas Munita, Sergio Luis; Dei-Cas, E Proyecto (2002)
Infants: An unrecognized reservoir of Pneumocystis carinii Vargas, Sergio L.; Ponce, C.A. Proyecto www.pedaids.org Grant #51153-26 PG (2001)
Pathogenic mechanisms in the human primary infection by Pneumocystis carinii and their relevance for sudden infant death syndrome Vargas Munita, Sergio Luis; Ponce, Carolina A Proyecto (2001)
Pathogenic mechanisms in the human primary infection by Pneumocystis carinii and their relevance for sudden infant death syndrome. Vargas Munita, Sergio Luis; Dei-Cas, Eduardo Proyecto Proyecto de colaboración internacional 7011059 (2001)
Academic Link between the University of Oxford and the University of Chile Vargas, Sergio L.; Wakefield, Ann E Proyecto (2000)
Infants: An unrecognized source of contagion of Pneumocystis carinii for immunocompromised susceptible patients Vargas Munita, Sergio Luis; Ponce, Carolina A Proyecto (1996)


Importance of tissue sampling, laboratory methods, and patient characteristics for detection of Pneumocystis in autopsied lungs of non-immunosuppressed individuals Vargas S.L.; Ponce C.; Bustamante R.; Calderón E.; Nevez G.; De Armas Y.; Matos O.; Miller R.F.; Gallo M.J. Review ISI SCOPUS EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY INFECTIOUS DISEASES (2017)
Dinámica y patología del barrido mucociliar como mecanismo defensivo del pulmón y alternativas farmacológicas de tratamiento Francisco Pérez B; Andrea Méndez G; Andrea Lagos R; Sergio L Vargas M Review SCIELO SCOPUS REVISTA MEDICA DE CHILE (2014)