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Catherine Andrea Sanchez Nuñez

Clinical Researcher

CLÍNICA LAS CONDES

Santiago, Chile

Cancer de Próstata; Terapia; Urología; Vesículas extracelulares; exosomas; Diagnóstico

Biomedical Sciences, UNIVERSIDAD DE CHILE. Chile, 2008
Veterinarian, UNIVERSIDAD DE CHILE. Chile, 2000
Veterinary Sciences, UNIVERSIDAD DE CHILE. Chile, 1998

Postdoctoral Researcher Full Time

UNIVERSIDAD DE CHILE

Medicine

Santiago, Chile

2009 - 2011

Postdoctoral researcher Full Time

Universidad de Chile

Santiago, Chile

2009 - 2011
Medico Veterinario Part Time

Clinica Veterinaria Recoleta

Santiago, Chile

2001 - 2008
Profesor Part Time

Universidad Pedro de Valdivia

Santiago, Chile

2007 - 2009
Research core coordinator and Clinical Researcher Full Time

Clinica las Condes

Santiago, Chile

2011 - At present
Research Subdirector Full Time

Clinica Las Condes

Santiago, Chile

2021 - At present

2019-to date: Guidance: PhD degree thesis. Student: Andrés Vega Avalos. Program: PhD in Medical Sciences, Universidad de Chile.
2014-2016: Guidance: Profesional Degree Seminar. Student: Eliana Andahur. Career: Ingenería en Biotecnología. Universidad de Chile.
2014: Guidance: Profesional Practice. Student: Javiera Ríos. Career: Bioquímica. Universidad de Chile.
2011-2014: Tutor for Research Semester. Students: Ikuno Yamauchi, Hideki Yanawa, Yoshiaki Yoshioka, Atsuna Matsumoto. Career: Medicine. Tokio Medical and Dental University (TMDU), Japón.

Patente de invención / 2020 - 000899, aceptada el 09/06/2022
Título: MÉTODO NO INVASIVO PARA EL DIAGNÓSTICO IN VITRO DE CÁNCER DE PRÓSTATA BASADO EN LA DETECCIÓN DE miRNAs PRESENTES EN VESÍCULAS EXTRACELULARES (EXOSOMAS) DE PLASMA O DE ORINA
Inventora.


Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles Erdbrugger, Uta; Blijdorp, Charles J.; Bijnsdorp, Irene V.; Burger, Dylan; Bussolati, Benedetta; Byrd, James Brian; Clayton, Aled; Dear, James W.; Grange, Cristina; Holthofer, Harry; et al. Article ISI JOURNAL OF EXTRACELLULAR VESICLES (2021)
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Théry C.; Witwer K.W.; Aikawa E.; Alcaraz M.J.; Andriantsitohaina R.; Antoniou A.; Arab T.; Archer F.; Atkin-Smith G.K.; Ayre D.C.; et al. Article ISI SCOPUS (2018)
Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and pre-metastatic niche Sanchez C.A.; Valenzuela R.; Castellón E.A. Article SCOPUS Oncotarget (2016)
miRNAs in exosomes from prostate cancer cells modify normal fibroblasts and osteoblasts favoring tumor spread and metastasis Andahur, Eliana; Ramos, Chistian; Fulla, Juan A. Article ISI CANCER RESEARCH (2016)
Y chromosome microdeletion prevalence in infertile Chilean men Article ISI SCOPUS REVISTA INTERNACIONAL DE ANDROLOGIA (2016)
Identification of microRNAs from exosomes of bulk and stem cells from prostate cancer by next generation sequencing Valenzuela, Rodrigo; Castellon, Enrique; Ramos, Christian; Carlos Trivino, Juan Article ISI CANCER RESEARCH (2015)
Proapoptotic effect of endocannabinoids in prostate cancer cells Orellana Serradell O; Poblete, CE; Sanchez C; Gallegos, I.; Huidobro C.; Contreras, HR Article ISI SCOPUS ONCOLOGY REPORTS (2015)
Proapoptotic effect of endocannabinoids in prostate cancer cells. Orellana-Serradell, O; Poblete, C E; Sanchez, C; Castellón, E A; Gallegos, I; Huidobro, C; Llanos, M N; Contreras, H R Article Oncology reports (2015)
Is active surveillance a safe alternative in the management of localized prostate cancer? Pathological features of radical prostatectomy specimens in potential candidates for active surveillance Zambrano, Norman; Petric, Militza; Figueroa, Andres; Fleck, Daniela; Mercado, Alejandro; Sanchez, Catherine; Fullá, Juan Article International braz j urol (2014)
Is active surveillance a safe alternative in the management of localized prostate cancer? Pathological features of radical prostatectomy specimens in potential candidates for active surveillance Norman, Z; Militza, P; Andres, F; Daniela, F; ALEJANDRO M; Catherine, S; Juan F. Article ISI SCOPUS INTERNATIONAL BRAZ J UROL (2014)
Quality of Life Evaluation in Patients with Prostate Cancer Treated with Radical Prostatectomy: Prospective Study and Results of Eighteen Months of Follow-Up Fullá, J.; Rosenfeld, R.; Sanchez, C.; Oyanedel, F.; Valenzuela, R.; Campero, JM.; Valdevenito, R.; Heinz, N.; Ramos, C. Article JOURNAL OF MENS HEALTH (2014)
Quality of Life Evaluation in Patients with Prostate Cancer Treated with Radical Prostatectomy: Prospective Study and Results of Eighteen Months of Follow-Up Fullá, J.; Rosenfeld, R.; Sanchez, C.; Oyanedel, F.; Valenzuela, R.; Campero, JM.; Valdevenito, R.; Heinz, N.; Ramos, C. Article ISI SCOPUS Journal of Mens Health (2014)
Cirugía Urológica en pacientes de 80 años y más. ¿Es la edad un factor de riesgo para el desarrollo de complicaciones postoperatorias? 13. Campos D., Fleck D., Fulla J., Oyanedel F., Sánchez C., Rojas E., Campero J.M., Valdevenito R., Hinrichs A., Zambrano N., Susaeta R., Álvarez E., Palma C., Chiang H., Salgado G., Rosenfeld R., Ramos C. Article Rev Chil Urol (2013)
Conociendo y comprendiendo la célula cancerosa: fisiopatología del cáncer. Sanchez C Article LILACS REVISTA MEDICA CLINICA LAS CONDES (2013)
Conociendo y comprendiendo la célula cancerosa: fisiopatología del cáncer. Sanchez, Catherine Article Rev Med Clin Condes (2013)
Esfingosina-1-fosfato y cánceres urológicos: identificando potenciales blancos terapéuticos en su Metabolismo y Señalización Mercado, A; Marchant, F; Gallegos, I; Fullá, J; Sánchez, C; Contreras, H; Castellón, E. Article Revista Chilena de Urología (2013)
Evaluación de la calidad de vida en pacientes con cáncer de próstata tratados mediante prostatectomía radical. Estudio prospectivo y resultados a seis meses de seguimiento Fulla, J; Rosenfeld, R; Fleck, D; Campos, D; Oyanedel, F; Ramos, C; Campero, J; Valdevenito, R; Sanchez, C; Alvarez, E; Zambrano, N; Hinrichs, A; Susaeta, R; Salgado, G; Nicolas, H. Article Revista Chilena de Urología (2013)
PCA3 sensitivity and specificity for prostate cancer detection in patients with abnormal PSA and/or suspicious digital rectal examination. First Latin American experience Ramos CG; Valdevenito, R; Vergara, I; Anabalon, P; Sanchez C; Fulla J. Article ISI SCOPUS Urologic Oncology: Seminars and Original Investigations (2013)
PCA3 sensitivity and specificity for prostate cancer detection in patients with abnormal PSA and/or suspicious digital rectal examination. First Latin American experience. Ramos CG, Valdevenito R, Vergara I, Anabalon P, Sanchez C, Fulla J Article Urol Oncol (2013)
Riesgo de malignidad en masas renales sólidas menores a cuatro centímetros Oyanedel, F; Campos, D.; Fleck, D; Fulla, J; Ramos, C; Valdevenito, R; Sanchez, C; Alvarez, E; Rosenfeld, R; Zambrano, N; Hinrichs, A; Susaeta, R; Salgado, G; Campero, J. Article Revista Chilena de Urología (2013)
Riesgo de malignidad en masas renales sólidas menores a cuatro centímetros. Oyanedel, F Article LILACS Revista Chilena de Urología (2013)
Pharmacoperone IN3 enhances the apoptotic effect of leuprolide in prostate cancer cells by increasing the gonadotropin-releasing hormone receptor in the cell membrane Sanchez C.A.; Mercado A.J.; Contreras, H. R.; Cabezas J.C.; Huidobro C.C.; Castellón E.A. Article ISI SCOPUS Anti-Cancer Drugs (2012)
Pharmacoperone IN3 enhances the apoptotic effect of leuprolide in prostate cancer cells by increasing the gonadotropin-releasing hormone receptor in the cell membrane. Sánchez, Catherine A; Mercado, Alejandro J; Contreras, Héctor R; Cabezas, Juan C; Huidobro, Christian C; Castellón, Enrique A Article Anti-cancer drugs (2012)
Chemotherapy Sensitivity Recovery of Prostate Cancer Cells by Functional Inhibition and Knock Down of Multidrug Resistance Proteins Sanchez C; Mercado A.; Contreras, HR; Mendoza, P; Cabezas J.; Acevedo C.; Huidobro C. Article ISI SCOPUS Prostate (2011)
Chemotherapy sensitivity recovery of prostate cancer cells by functional inhibition and knock down of multidrug resistance proteins. Sánchez, Catherine; Mercado, Alejandro; Contreras, Héctor R; Mendoza, Patricia; Cabezas, Juan; Acevedo, Cristian; Huidobro, Christian; Castellón, Enrique A Article The Prostate (2011)
EXPRESIÓN Y ACTIVIDAD DE PROTEÍNAS DE MULTIRRESISTENCIA A DROGAS (MDR) EN LÍNEAS CELULARES DE CÁNCER DE PRÓSTATA Mercado A.; Sanchez C; Fulla J. Article LILACS Revista Chilena de Urología (2010)
Expresión y actividad de proteínas de multirresistencia a drogas (MDR) en líneas celulares de cáncer de próstata. 9. Mercado, A.; Sánchez, C.; Fulla, J.; Ledezma, R.; Acevedo, C.; Cabezas, J.; Huidobro, C.; Contreras, HR.; Castellón, EA Article Revista Chilena de Urología (2010)
Evaluation of MENT on primary cell cultures from benign prostatic hyperplasia and prostate carcinoma Mendoza, P; Sanchez C; Contreras, HR; Vergara, J.; Acevedo C.; Cabezas J.; Huidobro C.; Noe G Article ISI SCOPUS International Journal of Andrology (2009)
Evaluation of MENT on primary cell cultures from benign prostatic hyperplasia and prostate carcinoma. Mendoza, Patricia; Sánchez, Catherine; Contreras, Héctor R; Vergara, Jorge; Acevedo, Cristian; Cabezas, Juan; Huidobro, Christian; Noé, Gabriela; Castellón, Enrique A Article International journal of andrology (2009)
Expression of Multidrug Resistance Proteins in Prostate Cancer Is Related With Cell Sensitivity to Chemotherapeutic Drugs Sanchez C; Mendoza, P; Contreras, HR; Vergara, J.; McCubrey, JA; Huidobro C. Article ISI SCOPUS PROSTATE (2009)
Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs. Sánchez, Catherine; Mendoza, Patricia; Contreras, Héctor R; Vergara, Jorge; McCubrey, James A; Huidobro, Christian; Castellón, Enrique A Article The Prostate (2009)
Gonadotropin Releasing Hormone Analogs Induce Apoptosis by Extrinsic Pathway Involving p53 Phosphorylation in Primary Cell Cultures of Human Prostatic Adenocarcinomas Clementi M.; Sanchez C; Benitez, DA; Contreras, HR; Huidobro C.; Cabezas J.; Acevedo C. Article ISI SCOPUS PROSTATE (2009)
Gonadotropin releasing hormone analogs induce apoptosis by extrinsic pathway involving p53 phosphorylation in primary cell cultures of human prostatic adenocarcinomas. Clementi, Marisa; Sánchez, Catherine; Benitez, Dixan A; Contreras, Héctor R; Huidobro, Christian; Cabezas, Juan; Acevedo, Cristian; Castellón, Enrique A Article The Prostate (2009)
Exploring transplacental transmission of Pneumocystis oryctolagi in first-time pregnant and multiparous rabbit does Chabe M; Aliouat, EM; Durand-Joly, I; Gantois, N; Conseil, V; López C.; Duriez, T; Dei-Cas, E; Vargas, SL Article ISI SCOPUS MEDICAL MYCOLOGY (2007)
Exploring transplacental transmission of Pneumocystis oryctolagi in first-time pregnant and multiparous rabbit does. Sanchez, Catherine A; Chabé, Magali; Aliouat, El Moukhtar; Durand-Joly, Isabelle; Gantois, Nausicaa; Conseil, Valérie; López, Claudia; Duriez, Thérèse; Dei-Cas, Eduardo; Vargas, Sergio L Article Medical mycology (2007)
Effect of leuprolide and cetrorelix on cell growth, apoptosis and GnRH receptor expression in primary cell cultures from human prostate carcinoma Castellón, E.; Clementi, M.; Hitschfeld, C.; Sánchez, C.; Benítez, D.; Sáenz, L.; Contreras, C.; Huidobro, C. Article Cancer Investigation (2006)
Effect of leuprolide and cetrorelix on cell growth, apoptosis, and GnRH receptor expression in primary cell cultures from human prostate carcinoma Castellón E.; Clementi M.; Hitschfeld, C; Sanchez C; Benitez D.; SÃ¡enz L.; Contreras H.; Huidobro C. Article ISI SCOPUS CANCER INVESTIGATION (2006)
Effect of GnRH analogs on the expression of TrkA and p75 neurotrophin receptors in primary cell cultures from human prostate adenocarcinoma Sanchez C; Clementi M.; Benitez D.; Contreras H.; Huidobro C.; Castellón E. Article ISI SCOPUS PROSTATE (2005)
Effect of GnRH analogs on the expression of TrkA and p75 neurotrophin receptors in primary cell cultures from human prostate adenocarcinoma. Sánchez, Catherine; Clementi, Marisa; Benitez, Dixan; Contreras, Hector; Huidobro, Christian; Castellon, Enrique Article The Prostate (2005)
Pregnancy and asymptomatic carriage of Pneumocystis jiroveci [3] Ponce, C.A.; Sanchez C.A.; Bustamante, R; Juarez, G Article EMERGING INFECTIOUS DISEASES (2003)
Pregnancy and asymptomatic carriage of Pneumocystis jiroveci. Vargas, Sergio L; Ponce, Carolina Angelica; Sanchez, Catherine Andrea; Ulloa, Ana Victoria; Bustamante, Rebeca; Juarez, Guido Article Emerging infectious diseases (2003)
Purificación de antígenos de Fasciola hepatica mediante electroelución y su aplicación diagnóstica mediante western blot en la infección animal Fredes, F; Sánchez, C; Gorman, T; Alcaíno, H. Article Parasitología al día (2001)
Purificación de antígenos de Fasciola hepatica mediante electroelución y su aplicación inmunodiagnóstica mediante Western Blot en la infección animal Fredes, Fernando; Sanchez, Catherine; GORMAN, TEXIA; ALCAINO, HECTOR Article PARASITOLOGIA AL DIA


Vesículas extracelulares derivadas de orina de pacientes con cáncer de vejiga: papel en el diagnóstico y mediación del efecto de campo. Mercado, Alejandro J.; Sanchez, Catherine Proyecto (2019)
Desarrollo de una metodología diagnóstica no invasiva de cáncer de próstata, mediante la detección de exosomas en biofluidos Sanchez, Catherine Proyecto (2018)
Evaluación proteómica de exosomas de cultivos primarios de cáncer de próstata para la identificación de proteínas asociadas a cáncer Sanchez, Catherine Proyecto (2018)
Exo-detección: Nuevo producto diagnóstico en cáncer de próstata mediante la detección de miRNAs en exosomas de pacientes con sospecha de cáncer de próstata Sanchez, Catherine Proyecto (2018)
STUDY ON THE ROLE OF SECRETORY MICRORNAS FROM TUMOR STEM CELLS IN THE MECHANISM OF THE PRIMARY AND METASTATIC NICHE ESTABLISHMENT IN PROSTATE CANCER FONDECYT (11121525) Proyecto 2012-2015 Inv. Responsable
EFFECT OF PHARMACOPERONE-MEDIATED INCREASE IN GNRH RECEPTOR EXPRESSION IN PLASMA MEMBRANE ON RADIOTHERAPY RESPONSE OF HUMAN PROSTATE CARCINOMA CELLS TREATED WITH GNRH ANALOGUES. FONDECYT (3090016) Proyecto 2008-2010 Inv. Responsable
Estudio sobre la expresión y regulación de proteínas relacionadas con la multirresistencia a drogas en adenocarcinoma prostático humano de diferentes grados de malignidad. Recuperación in vitro de la sensibilidad de las FONDECYT (1070827) Proyecto 2007-2010 Tesista


Cambia el color y el riesgo... Nuevo escenario para el cáncer de próstata en Chile Eliana Andahur; Alejandro Mercado Review ISI SCIELO SCOPUS Revista Medica de Chile (2019)