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Octavio Andrés Orellana Serradell

Investigador Postdoctoral

Universidad de Chile

Santiago, Chile

Cáncer Progresión y desarrollo tumoral Migración celular Inflamación Dinámicas inter organelares Calcio Interacciones proteína-proteína

Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2018
Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2010

Ayudante del Curso de Inglés para Doctorados Other

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2019 - At present

Investigador Postdoctoral Full Time

Laboratorio Oncología Celular y Molecular

Santiago, Chile

2017 - 2018
Investigador Postdoctoral Full Time

Laboratorio Inmunidad Innata

Chile

2018 - 2020
Investigador Postdoctoral Full Time

MINICAD

Chile

2020 - At present


The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium Entry Saldias, Maria Paz; Cruz, Pablo; Silva, Ian; Orellana-Serradell, Octavio; Lavanderos, Boris; Maureira, Diego; Pinto, Raquel; Cerda, Oscar Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis Landskron, Glauben; Dubois-Camacho, Karen; Orellana-Serradell, Octavio; De la Fuente, Marjorie; Parada-Venegas, Daniela; Bitrán, Mirit; Diaz-Jimenez, David; Tang, Shuang; Cidlowski, John A.; Li, Xiaoling; Molina, Hector; Gonzalez, Carlos M.; Simian, Daniela; Lubascher, Jaime; Pola, Victor; MONTECINO-LEONARD, MARTIN ALEJANDRO; Blokzijl, Tjasso; Faber, Klaas Nico; González, María Julieta; QUERA-PINO, RODRIGO ENRIQUE; HERMOSO-RAMELLO, MARCELA ALEJANDRA Article ISI SCOPUS Cells (2022)
TRP Channels Interactome as a Novel Therapeutic Target in Breast Cancer Saldias, Maria Paz; Maureira, Diego; Orellana-Serradell, Octavio; Silva, Ian; Lavanderos, Boris; Cruz, Pablo; Torres, Camila; Caceres, Monica; Cerda, Oscar Article ISI FRONTIERS IN ONCOLOGY (2021)
DOES PEER REVIEWING FOR COVID-19-RELATED PAPERS STILL WORK? Orellana-Serradell, Octavio; Diaz, Magda C; Gonzalez, Maria F.; Gutierrez, Myriam; Herrera, Daniela; Jara, Daniela; Maureira, Diego; Ruiz-Fuentes, Jenny; Sanhueza, Sofía; Leyton, Lisette Article Google Scholar, DOAJ, CrossRef, Digital Biography & Library Project (dblp), CLOCKSS Frontiers Research Metrics & Analytics (2020)
SNAIL expression correlates with the translocation of syndecan-1 intracellular domain into the nucleus in prostate cancer cell lines FarfÃ¡n N.; Orellana-Serradell O.; Herrera D.; Chrzanowsky D.; Cubillos P.; MarÃn G.; GarcÃa De Herreros A.; CastellÃ³n E.A.; Contreras H.R. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020)
TRP Channels Regulation of Rho GTPases in Brain Context and Diseases Lavanderos, Boris; Silva, Ian; CRUZ-JOHNSON, PABLO CHRISTIAN; Orellana-Serradell, Octavio; Saldias, Maria Paz; CERDA-ARANCIBIA, OSCAR ALEJANDRO Article ISI SCOPUS Frontiers in Cell and Developmental Biology (2020)
Interleukin 33/ST2 Axis Components Are Associated to Desmoplasia, a Metastasis-Related Factor in Colorectal Cancer Landskron, Glauben; De la Fuente Lopez, Marjorie; Dubois-Camacho, Karen; Diaz-Jimenez, David; Orellana-Serradell, Octavio; Romero, Diego; Sepulveda, Santiago A.; Salazar, Christian; Parada-Venegas, Daniela; Quera, Rodrigo; Simian, Daniela; Gonzalez, Maria-Julieta; Kronberg, Udo; Abedrapo, Mario; Gallegos, Ivan; Contreras, Hector R.; Pena, Cristina; Diaz-Araya, Guillermo; Carlos Roa, Juan; Hermoso, Marcela A. Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
Silencing of the transcriptional factor ZEB1 alters the steroidogenic pathway, and increases the concentration of testosterone and DHT in DU145 cells Herrera, D.; Orellana-Serradell, O.; Villar, P.; Torres, M. J.; Paciucci, R.; Castellon, E. A.; Contreras, H. R. Article ISI SCOPUS ONCOLOGY REPORTS (2019)
The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines Octavio Orellana-Serradell, Daniela Herrera, Enrique A Castellón, Héctor R Contreras Article ISI ASIAN JOURNAL OF ANDROLOGY (2019)
The transcription factor ZEB1 promotes an aggressive phenotype in prostate cancer cell lines Orellana-Serradell, O; Herrera, D; Castellon EA.; Contreras, HR Article ISI SCOPUS ASIAN JOURNAL OF ANDROLOGY (2018)
Proapoptotic effect of endocannabinoids in prostate cancer cells Orellana Serradell O; Poblete, CE; Sánchez C; Castellon EA.; Gallegos, I.; Huidobro C.; Llanos, MN; Contreras, HR Article ISI SCOPUS ONCOLOGY REPORTS (2015)


Suppression of SDC-1 expression by overexpression of ZEB1/ZEB2 in prostate cancer cells Contreras H.; Farfan, N; Orellana Serradell O; Chrzanowsky D.; Castellón E. Abstract ISI EUROPEAN JOURNAL OF CANCER (2015)


Regulation of the activity and localization of TRPC6 channels by VAPA and its role in cancer progression Orellana-Serradell, O Proyecto (2021)
Role of Cortisol Signaling on intestinal steroidogenesis in ulcerative colitis FONDECYT (1170648) Proyecto 2018-2021 Postdoctorado
The transcription factors ZEB1/SNAIL induce in vitro cell malignancy and cancer stem cell phenotype through epithelial-mesenchymal transition in prostate cells, increasing androgen synthesis capacity and resistance FONDECYT (1151214) Proyecto 2015-2019 Tesista
EXPRESSION OF SYNDECANS IS DOWN REGULATED BY TRANSCRIPTION FACTOR SNAIL DURING EPITHELIAL MESENCHYMAL TRANSITION IN PROSTATE CANCER FONDECYT (1110269) Proyecto 2011-2015 Investigador(a)

13

Octavio Orellana

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

7

Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

6

Enrique Castellón

Profesor Titular.

Oncología Básico-Clínica

UNIVERSIDAD DE CHILE

Santiago, Chile

2

Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

2

IVAN GALLEGOS

PATHOLOGIST, LABORATORY DIRECTOR

PATHOLOGY

HOSPITAL CLINICO DE UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1

Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1

María José Torres

Docente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Daniela Parada

Asistente de investigación

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

1

Nancy Farfán

Post-doc.

Farmacología

Universidad de Chile

Santiago, Chile

1

Santiago Sepúlveda

Profesional Tecnólogo Médico

Anatomía Patológica

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Glauben Landskron

Academic Researcher

Escuela de Medicina

Universidad Finis Terrae

Santiago, Chile

1

Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

1

Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

1

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1

Catherine Sanchez

Clinical Researcher

Dirección Académica

CLÍNICA LAS CONDES

Santiago, Chile