Man

Monica Andrea Caceres Lluch

Profesor asociado

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Biologia celular de la reparación tisular. Marcadores temprano de Envejecimiento tanto en sangre como en tejidos.. Biologia celular del envejecimiento y de los tejidos periodontales.

Educación

  •  Farmacologia, UNIVERSIDAD DE CHILE. Chile, 2011
  •  Ingeniero en Biotecnologia Molecular, UNIVERSIDAD DE CHILE. Chile, 2002

Experiencia Académica

  •   Profesor asociado Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2021 - At present

  •   Profesor asistente Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Chile

    2013 - 2021

Experiencia Profesional

  •   Profesor asistente Full Time

    Universidad de Chile

    Chile

    2013 - 2021

  •   Profesor asociado Full Time

    Universidad de Chile

    Santiago, Chile

    2021 - At present


 

Article (34)

Aging envisage imbalance of the periodontium: A keystone in oral disease and systemic health

Villalobos, Veronica; Garrido, Mauricio; Reyes, Antonia; Fernandez, Christian; Diaz, Catalina; Torres, Vicente A.; Gonzalez, Pablo A.; Caceres, Monica

Article ISI
FRONTIERS IN IMMUNOLOGY  (2022)

Relationship Between Endothelial and Angiogenesis Biomarkers Envisage Mortality in a Prospective Cohort of COVID-19 Patients Requiring Respiratory Support

Maldonado, Felipe; Morales, Diego; Diaz-Papapietro, Catalina; Valdes, Catalina; Fernandez, Christian; Valls, Nicolas; Lazo, Marioli; Espinoza, Carolina; Gonzalez, Roberto; Gutierrez, Rodrigo; Jara, Alvaro; Romero, Carlos; Cerda, Oscar; Caceres, Monica

Article ISI
FRONTIERS IN MEDICINE  (2022)

Cellular response of human apical papilla cells to calcium hydroxide and tricalcium silicate-based cements

Garrido, Mauricio; Morales, Diego; Saldias, Maria Paz; Fernandez, Christian; Villalobos, Veronica; Cerda, Oscar; Caceres, Monica

Article ISI
BMC ORAL HEALTH  (2021)

Histatin-1 is a novel osteogenic factor that promotes bone cell adhesion, migration, and differentiation

Torres, Pedro; Hernandez, Nadia; Mateluna, Carlos; Silva, Patricio; Reyes, Montserrat; Solano, Luis; Venegas, Sebastian; Criollo, Alfredo; Nazmi, Kamran; Bikker, Floris J.; Bolscher, Jan G. M.; Garrido, Mauricio; Caceres, Monica; Torres, Vicente A.

Article ISI
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE  (2021)

PPI-MASS: An Interactive Web Server to Identify Protein-Protein Interactions From Mass Spectrometry-Based Proteomics Data

Gonzalez-Avendano, Mariela; Zuniga-Almonacid, Simon; Silva, Ian; Lavanderos, Boris; Robinson, Felipe; Rosales-Rojas, Roberto; Duran-Verdugo, Fabio; Gonzalez, Wendy; Caceres, Monica; Cerda, Oscar; Vergara-Jaque, Ariela

Article ISI
FRONTIERS IN MOLECULAR BIOSCIENCES  (2021)

TMPRSS11a is a novel age-altered, tissue specific regulator of migration and wound healing

Fernandez, Christian; Burgos, Andres; Morales, Diego; Rosales-Rojas, Roberto; Canelo, Javiera; Vergara-Jaque, Ariela; Vieira, Gabriel Viliod; Alves da Silva, Rodrigo Alberto; Sales, Katiuchia Uzzun; Conboy, Michael J.; Bae, Eun Ji; Park, Kang-Sik; Torres, Vicente A.; Garrido, Mauricio; Cerda, Oscar; Conboy, Irina M.; Caceres, Monica

Article ISI
FASEB JOURNAL  (2021)

TRP Channels Interactome as a Novel Therapeutic Target in Breast Cancer

Saldias, Maria Paz; Maureira, Diego; Orellana-Serradell, Octavio; Silva, Ian; Lavanderos, Boris; Cruz, Pablo; Torres, Camila; Caceres, Monica; Cerda, Oscar

Article ISI
FRONTIERS IN ONCOLOGY  (2021)

Effect of sevoflurane and propofol on tourniquet-induced endothelial damage: a pilot randomized controlled trial for knee-ligament surgery

Maldonado, Felipe; Morales, Diego; Gutierrez, Rodrigo; Barahona, Maximiliano; Cerda, Oscar; Caceres, Monica

Article ISI
BMC ANESTHESIOLOGY  (2020)

KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis

Rivas, Jose; Diaz, Nicolas; Silva, Ian; Morales, Danna; Lavanderos, Boris; Alvarez, Alhejandra; Paz Saldias, Maria; Pulgar, Eduardo; Cruz, Pablo; Maureira, Diego; Flores, Guillermo; Colombo, Alicia; Blanco, Constanza; Contreras, Hector R.; Jana, Fabian; Gallegos, Ivan; Concha, Miguel L.; Vergara-Jaque, Ariela; Poblete, Horacio; Gonzalez, Wendy; Varela, Diego; Trimmer, James S.; Caceres, Monica; Cerda, Oscar

Article ISI
FASEB JOURNAL  (2020)

A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer

Canales J.; Morales D.; Blanco C.; Rivas J.; Diaz N.; Angelopoulos I.; Cerda O.

Article ISI SCOPUS
FRONTIERS IN PHYSIOLOGY  (2019)

EB1-and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion

Blanco, Constanza; Morales, Danna; Mogollones, Ignacio; Vergara-Jaque, Ariela; Vargas, Carla; Alvarez, Alhejandra; Riquelme, Denise; Leiva-Salcedo, Elias; Gonzalez, Wendy; Morales, Diego; Maureira, Diego; Aldunate, Ismael; Caceres, Monica; Varela, Diego; Cerda, Oscar

Article ISI SCOPUS
FASEB JOURNAL  (2019)

Aged blood factors decrease cellular responses associated with delayed gingival wound repair

Saldías M.P.; Fernández C.; Morgan A.; Díaz C.; Morales D.; Jaña F.; Gómez A.; Silva A.; Briceño F.; Oyarzún A.; Maldonado F.; Cerda O.; Smith P.C.; Cáceres M.

Article ISI SCOPUS
PLOS ONE  (2017)

Methylglyoxal and methylglyoxal-modified collagen as inducers of cellular injury in gingival connective tissue cells.

Retamal, I N; Hernández, R; González-Rivas, C; Cáceres, M; Arancibia, R; Romero, A; Martínez, C; Tobar, N; Martínez, J; Smith, P C

Article
Journal of periodontal research  (2016)

Casein kinase-mediated phosphorylation of serine 839 is necessary for basolateral localization of the Ca2+-activated non-selective cation channel TRPM4

Cerda O.; Cáceres M.; Park, KS; Leiva-Salcedo, E; Romero A.; Varela D.; Trimmer, JS; Stutzin A.

Article ISI SCOPUS
Pflugers Archiv European Journal of Physiology  (2015)

Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E-2 production in human gingival fibroblasts

Romero A.; Cáceres M.; Arancibia, R.; Silva D.; Couve, E.; Martínez C; Martinez, J.; Smith, PC

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2015)

Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel

Sarmiento D.; Montorfano I.; Cerda O.; Cáceres M.; Becerra, A; Cabello-Verrugio, C; Elorza, AA; Riedel C.; Tapia, P; Velasquez LA; Varela D.; Simon F.

Article ISI SCOPUS
Microvascular Research  (2015)

TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility

Cáceres M.; Ortiz, L; Recabarren, T; Romero A.; Colombo, A; Leiva-Salcedo, E; Varela D.; Rivas J.; Silva I.; Morales, D; Campusano, C; Almarza O.; Simon F.; Toledo, H; Park, KS; Trimmer, JS; Cerda O.

Article ISI SCOPUS
PLOS ONE  (2015)

Defective Wound-healing in Aging Gingival Tissue

Cáceres M.; Oyarzun A.; Smith, PC

Article ISI SCOPUS
JOURNAL OF DENTAL RESEARCH  (2014)

Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-kappa B pathway, NAD(P)H oxidase activation, and transient receptor potential melastatin 7 calcium channel activity

Sarmiento, Daniela; Montorfano, Ignacio; Cáceres, Mónica; Echeverría, Cesar; Fernandez, Ricardo; Cabello-Verrugio, Claudio; Cerda, Oscar; Tapia, Pablo; Simon, Felipe

Article ISI SCOPUS
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY  (2014)

Synthesis of nanostructured porous silica coatings on titanium and their cell adhesive and osteogenic differentiation properties

Inzunza D.; Covarrubias, C; Von Marttens, A; Leighton Y.; Carvajal, JC; Valenzuela F.; Diaz-Dosque, M; Mendez, N.; Martínez C; Pino, AM.; Rodriguez, JP; Cáceres M.; Smith P.

Article ISI SCOPUS
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A  (2014)

Chitosan and platelet-derived growth factor synergistically stimulate cell proliferation in gingival fibroblasts

Silva D.; Arancibia, R.; Tapia C.; Acuna-Rougier, C; Diaz-Dosque, M; Cáceres M.; Martinez, J.; Smith, PC

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2013)

Effects of cigarette smoke and nicotine on cell viability, migration and myofibroblastic differentiation

Silva D.; Cáceres M.; Arancibia, R.; Martínez C; Martinez, J.; Smith, P. C.

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2012)

Effects of platelet-rich and -poor plasma on the reparative response of gingival fibroblasts

Cáceres M.; Martínez C; Martinez, J.; Smith, P. C.

Article ISI SCOPUS
Clinical Oral Implants Research  (2012)

Simvastatin alters fibroblastic cell responses involved in tissue repair

Cáceres M.; Romero A.; Copaja M; Diaz-Araya, G; Martinez, J.; Smith, PC

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2011)

Involvement of MT1-MMP and TIMP-2 in human periodontal disease

Oyarzun A.; Arancibia, R.; hidalgo, r.; Penafiel, C; Cáceres M.; Gonzalez, MJ; Martinez, J.; Smith, PC

Article ISI SCOPUS
Oral Diseases  (2010)

Cigarette smoke condensate stimulates urokinase production through the generation of reactive oxygen species and activation of the mitogen activated protein kinase pathways in human gingival fibroblasts

González R.; Arancibia, R.; Cáceres M.; Martinez, J.; Smith, PC

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2009)

Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts

Arancibia, R.; Cáceres M.; Martinez, J.; Smith, PC

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2009)

Tumor necrosis factor-alpha-stimulated membrane type 1-matrix metalloproteinase production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts

Smith, PC; Guerrero, J; Tobar, N.; Cáceres M.; Gonzalez, MJ; Martinez, J.

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2009)

c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway

Cáceres M.; Tobar, N.; Guerrero, J; Smith, PC; Martinez, J.

Article ISI SCOPUS
JOURNAL OF CELLULAR BIOCHEMISTRY  (2008)

Effect of platelet-rich plasma on cell adhesion, cell migration, and myofibroblastic differentiation in human gingival fibroblasts

Cáceres M.; hidalgo, r.; Sanz A.; Martinez, J.; Riera P.; Smith, PC

Article ISI SCOPUS
JOURNAL OF PERIODONTOLOGY  (2008)

RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NF kappa B-dependent mechanism

Tobar, N.; Cáceres M.; Santibanez, JF; Smith, PC; Martinez, J.

Article ISI SCOPUS
CANCER LETTERS  (2008)

Galectin-8 binds specific beta 1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells

Carcamo, C; Pardo E.; Oyanadel, C; Bravo-Zehnder, M; Bull, P; Cáceres M.; Martinez, J.; Massardo, L; Jacobelli, S.; González A; Soza A.

Article ISI SCOPUS
EXPERIMENTAL CELL RESEARCH  (2006)

Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-beta 1: role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways

Smith, PC; Cáceres M.; Martinez, J.

Article ISI SCOPUS
JOURNAL OF PERIODONTAL RESEARCH  (2006)

Overexpression of RhoA-GTP induces activation of the Epidermal Growth Factor Receptor, dephosphorylation of focal adhesion kinase and increased motility in breast cancer cells

Cáceres M.; Guerrero, J; Martinez, J.

Article ISI SCOPUS
EXPERIMENTAL CELL RESEARCH  (2005)

Letter (1)

Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-beta 1 and TNF-alpha

Guerrero, J; Tobar, N.; Cáceres M.; Espinoza L.; Escobar P.; Dotor, J; Smith, PC; Martinez, J.

Letter ISI SCOPUS
Breast Cancer Research and Treatment  (2010)

Proyecto (8)

TMPRSS11a as novel ageing-related marker involved in senescence during wound healing

Monica Cáceres

Proyecto
 (2018)

Crosstalk between gingival fibroblast and macrophages in wound healing during aging

Monica Cáceres

Proyecto
 (2015)

CROSSTALK BETWEEN GINGIVAL FIBROBLAST AND MACROPHAGES IN WOUND HEALING DURING AGING.

FONDECYT (11140064)

Proyecto
2014-2017
Inv. Responsable

Defectos en las respuestas celulares asociadas a la reparación durante el envejecimiento de tejidos periodontales

Facultad de Medicina (UINICIA 2013-44051)

Proyecto
2013-2014
Inv. Responsable

EL ENVEJECIMIENTO COMO MODULADOR DE LA REGENERACION E INFLAMACION PERIODONTAL.

FONDECYT (3120041)

Proyecto
2011-2014
Inv. Responsable

DOCTORADO EN FARMACOLOGIA

PFCHA (24100027)

Proyecto
2010-2011
Inv. Responsable

Mecanismos de la regeneracion

Becas Chile (10071)

Proyecto
2009-2009
Tesista

Subcontrato tecnologico Corfo

Monica Cáceres

Proyecto
 (0)

Review (3)

Gingival Wound Healing: An Essential Response Disturbed by Aging?

Smith, PC; Cáceres M.; Martínez C; Oyarzun A.; Martinez, J.

Review ISI SCOPUS
JOURNAL OF DENTAL RESEARCH  (2015)

Research on growth factors in periodontology

Smith, PC; Martínez C; Cáceres M.; Martinez, J.

Review ISI
PERIODONTOLOGY 2000  (2015)

Diabetes y su impacto en el territorio periodontal

Smith P.; Retamal, I; Cáceres M.; Romero A.; Silva D.; Arancibia, R.; Martínez C

Review SCIELO
REVISTA CLINICA DE PERIODONCIA, IMPLANTOLOGIA Y REHABILITACION ORAL  (2012)

40
Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

27
Jorge Martinez

Profesor Titular

Laboratorio de Biología Celular

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE ALIMENTOS (INTA), UNIVERSIDAD DE CHILE

Santiago, Chile

13
Oscar Cerda

Associate Professor

Molecular and Cellular Biology

Universidad de Chile

Santiago, Chile

7
Constanza Martinez

Profesor asociado

Facultad de Odontología

Universidad de Los Andes

Santiago de Chile, Chile

6
Patricio Smith

Associate Professor

Medicine / Dentistry

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Patricio Smith

Profesor Asociado

Odontología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

5
Diego Varela

Profesor Asociado

Fisiología y Biofísica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

5
Nicolas Tobar

Assistan Professor

Cellular and molecular Biology Laboratory

Institute of nutrition and food technology

Santiago, Chile

3
Darwin Leiva

Assistant professor

Biology

Universidad de Santiago de Chile

Santiago, Chile

3
Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

3
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

2
Pablo Tapia

Jefe Técnico Unidad de Paciente Crítico (UPC)

Unidad Paciente Critico (UPC)

Hospital Clinico Metropolitano La Florida

Santiago, Chile

2
Felipe Maldonado

Médico Anestesiólogo - Profesor Asistente

Anestesiología y Medicina Perioperatoria

Universidad de Chile

Santiago, Chile

2
Alicia Colombo

Profesora Asociada/Director Científico Biobanco de Tejidos y Fluidos de la Universidad de Chile

Departamento de Anatomía Patológica

Universidad de Chile

Santiago, Chile

2
Ariela Vergara

Associate Professor

Bioinformatics

UNIVERSIDAD DE TALCA

Talca, Chile

2
Fabián Jaña

Profesor Asistente

Departamento de Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

2
Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

1
César Echeverría

DIRECTOR DE INVESTIGACIÓN

Medicina

Universidad de Atacama

COPIAPO, Chile

1
Camilo Campusano

Doctorante

Genética Molecular y Microbiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Alvaro Becerra

Profesor Asociado

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

1
Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

1
Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

1
Ricardo Fernandez

Profesor Asociado A

Salud

Universidad de Los Lagos

Osorno, Chile

1
Ignacio Retamal

Assistant Professor

Centro de Oncología de Precisión

Universidad Mayor de Chile

Santiago, Chile

1
Luis Velasquez

Director and Full Professor

Medicine

Universidad SEK

Santiago, Chile

1
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
Miguel Concha

Full Professor

Anatomy and Developmental Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Eduardo Couve

1
Wendy Gonzalez

Director of the Center for Bioinformatics, Simulations and Modeling (CBSM)

Bioinformática

CENTRO DE BIOINFORMÁTICA Y SIMULACIÓN MOLECULAR (CBSM)/ UNIVERSIDAD DE TALCA

Talca, Chile

1
IVAN GALLEGOS

PATHOLOGIST, LABORATORY DIRECTOR

PATHOLOGY

HOSPITAL CLINICO DE UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Maria Massardo

Docente Investigador

Medicina

Universidad San Sebastián

Santiago, Chile

1
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

1
Alvaro Elorza

FULL PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

1
Luis Solano

Asistente de investigación

Universidad de Chile

Santiago, Chile

1
Ricardo Fernández

Associate Professor

Salud

Universidad de Los Lagos

Osorno, Chile

1
Mario Diaz

Profesor asistente

Instituto Ciencias odontológicas

UNIVERSIDAD DE CHILE FACULTAD DE ODONTOLOGIA

Santiago, Chile

1
cristian tapia

profesor asociado

ciencia de los alimentos y tecnologia quimica

University of Chile

santiago, Chile

1
Pedro Torres

Ayudante laboratorio

Universidad de Chile

Santiago, Chile

1
Alfredo von Marttens

DIRECTOR DE ESPECIALIDAD IMPLANTOLOGÍA BUCO MAXILO FACIAL

PRÓTESIS

ESCUELA GRADUADOS, FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
CRISTIAN COVARRUBIAS

PROFESOR ASOCIADO

INSTITUTO DE INVESTIGACIÓN EN CIENCIAS ODONTOLÓGICAS

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Patricio Silva

Investigados Postdoctoral

Departamento de Biología Celular y Molecular

Universidad de Chile

Santiago, Chile

1
Octavio Orellana

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

1
Andrea Soza

Profesor Asociado

Medicina y Ciencia

Universidad San Sebastián

Santiago, Chile

1
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

1
Claudia Oyanadel

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Evelyn Pardo

Investigadora Independiente

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

SANTIAGO , Chile

1
CLAUDIA CARCAMO

Profesor Asociado

neurology

PONTIFICIA UNIVERSIDADA CATÓLICA DE CHILE. DEPARTAMENTO DE NEUROLOGÍA

Santiago, Chile

1
Tatiana Recabarren

Research assistant FONDECYT regular 1211931

Universidad San Sebastián

Concepción, Chile

1
Montserrat Reyes

Profesor Asistente

Universidad de Chile

Santiago, Chile