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Maria Loreto Massardo Vega

Docente Investigador

Universidad San Sebastián

Santiago, Chile

Estudio de la patogenia de autoanticuerpos en enfermedades autoinmunes

Médico-Cirujano, UNIVERSIDAD DE CHILE. Chile, 1979
Reumatología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1982
Rheumatology, University of Bristol. Reino Unido, 1988

Profesor titular Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicina

Chile

1985 - 2017
Docente Investigador Full Time

Universidad San Sebastián

Medicina y Ciencia

Santiago, Chile

2017 - At present

Participación en la formación de médicos en su etapa formativa en medicina en reumatologia y en la especialidad de reumatologia y apoyo en la formación de tesistas y magisteres de pre y pos titulo en biologia celular

Difusion
En los media:
Sitio web educativo para pacientes con artritis reumatoide de PANLAR: www.artritisreumatoide.cl. Fan page 2017
SItio web educativo y face book: Hablemos de Lupus
Vinculación con el medio
Charlas a los pacientes y familiares de la Agrupación Lupus Chile 10 Agosto 2019: Lupus y Memoria y 2017 Qué es el lupus

PANLAR-Merck Rheumatology Prize for LatinAmerican Rheumatologists 2002

Pan American Associations for Rheumatology PANLAR

Estados Unidos, 2002

PANLAR-Merck Rheumatology Prize for LatinAmerican Rheumatologists 2002
Premio Academia de Medicina 2012

Instituto de Chile. Academia de Medicina

Chile, 2012

Premio Academia de Medicina 2012 en reconocimiento a la calidad de su investigación científica
Premio Conferencia Sociedad Médica de Santiago

SOCIEDAD MEDICA DE SANTIAGO

Chile, 2017

Premio Conferencia Sociedad Médica de Santiago "El compromiso cognitivo en el Lupus Neuro-Psiquiatrico"


Applying the 2019 EULAR/ACR lupus criteria to patients from an established cohort: A Latin American perspective Cardiel M. Article SCOPUS RMD Open (2020)
Clinical features, damage accrual, and survival in patients with familial systemic lupus erythematosus: data from a multi-ethnic, multinational Latin American lupus cohort Quintana, Rosana; Pons-Estel, Guillermo J; Roberts, Karen; Sacnún, Mónica; Serrano, Rosa; Nieto, Romina; Conti, Silvana; Gervasoni, Viviana; Catoggio, Luis J; Soriano, Enrique R; et al. Article LUPUS (2020)
Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale - Depression subscale scores: An individual participant data meta-analysis of 73 primary studies Yan, XW; Henry, M; Ismail, Z; Loiselle, CG; Al-Adawi, S; Braeken A.P.B.M.; BÃ¼el-Drabe N.; Chen, CK; Cheung, G; Conroy, RM; et al. Article ISI SCOPUS JOURNAL OF PSYCHOSOMATIC RESEARCH (2020)
A Consensus Position Paper From REAL-PANLAR Group About the Methodological Approach for the Accreditation Process of Centers of Excellence in Rheumatoid Arthritis in Latin America Cardiel, MH; Soriano, E; Castro, CA; Buitrago, D Article ISI SCOPUS JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2019)
Factors predictive of serious infections over time in systemic lupus erythematosus patients: data from a multi-ethnic, multi-national, Latin American lupus cohort Esposto A.; ChacÃ³n-DÃaz R. Article ISI SCOPUS LUPUS (2019)
Predictors of damage accrual in systemic lupus erythematosus: a longitudinal observational study with focus on neuropsychological factors and anti-neuronal antibodies Mimica, M; OrmeÃ±o R. Article ISI SCOPUS CLINICAL RHEUMATOLOGY (2019)
Antibodies and the brain: antiribosomal P protein antibody and the clinical effects in patients with systemic lupus erythematosus Massardo, Loreto Article ISI SCOPUS CURRENT OPINION IN NEUROLOGY (2018)
Predictive factors of flares in systemic lupus erythematosus patients: data from a multiethnic Latin American cohort Wojdyla, D; Catoggio, LJ; Bonfa, E; Sato, EI; Massardo, L; Reyes-Llerena, G; Alarcon, GS Article ISI SCOPUS LUPUS (2018)
Renal involvement in antineutrophil cytoplasmic antibodies (ANCA) associated vasculitides. Recommendations of the Chilean Societies of Nephrology and Rheumatology Miriam Alvo; Leopoldo Ardiles; Alberto Fierro; Annelise Goecke; Mirentxu Iruretagoyena; Roberto Jalil; Loreto Massardo; Sergio Palma; Emilio Roessler; Francisco Silva Article ISI SCIELO SCOPUS REVISTA MEDICA DE CHILE (2018)
Therapeutic Guidelines for Latin American Lupus Patients Methodology Bonfa, ESDD; Castaneda, MCA; Maldonado, CMG; Gamarra, AJI; Restrepo, JFM Article ISI SCOPUS JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2018)
Features associated with hematologic abnormalities and their impact in patients with systemic lupus erythematosus: Data from a multiethnic Latin American cohort González-Naranjo L.A.; Betancur O.M.; Jaramillo-Arroyave D.; Wojdyla, D; Rondón-Herrera F.; Vásquez-Duque G.M.; Quintana-Lopez, G; Tavares Brenol J.C.; Reyes-Llerena, G; Massardo, L; et al. Article ISI SCOPUS SEMINARS IN ARTHRITIS AND RHEUMATISM (2016)
A consensus of the Chilean Nephrology and Rheumatology Societies on renal involvement in systemic lupus erythematosus Aguirre V.; Alvo, M; Ardiles, L; Foster, C; Goecke, A; Jalil, R; Massardo, L; Palma, S; Roessler, E; Wurgaft, A Article ISI REVISTA MEDICA DE CHILE (2015)
Anti-N-methyl-D-aspartate receptor and anti-ribosomal-P autoantibodies contribute to cognitive dysfunction in systemic lupus erythematosus Massardo, L; Bravo-Zehnder, M; Calderon, J; Flores, P; Padilla, O; Aguirre, JM; Scoriels, L.; González, A Article ISI SCOPUS Lupus (2015)
Anti-Ribosomal P Protein Autoantibodies From Patients With Neuropsychiatric Lupus Impair Memory in Mice Bravo-Zehnder, M; Segovia-Miranda, F; Benito M.J.; Metz, C; Retamal, C; Alvarez, A; Massardo, L; Inestrosa, N. C.; González, A Article ISI SCOPUS ARTHRITIS & RHEUMATOLOGY (2015)
Beginning to Explore the High Rate of Work Limitation in Patients With Rheumatoid Arthritis in Chile Gracia Duran, Josefina; Valdivia, Gonzalo; Jacobelli, Sergio; Llanos, Leonidas; Gutierrez, Miguel; Leppe, Jaime Article ISI JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2015)
Late-onset systemic lupus erythematosus in Latin Americans: a distinct subgroup? Catoggio, LJ; Soriano, ER; Imamura, PM; Wojdyla, D; Jacobelli, S.; Massardo, L; Díaz, RC; Guibert-Toledano, M; Alvarellos A.; Saurit, V; et al. Article ISI SCOPUS Lupus (2015)
Pathogenicity of Lupus Anti-Ribosomal P Antibodies: Role of Cross-Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model Segovia-Miranda, F; Serrano, F; Dyrda A; Ampuero, E; Retamal, C; Bravo-Zehnder, M; Parodi, J; Zamorano, P; Valenzuela, D; Massardo, L; et al. Article ISI SCOPUS Arthritis and Rheumatology (2015)
REAL-PANLAR Project for the Implementation and Accreditation of Centers of Excellence in Rheumatoid Arthritis Throughout Latin America A Consensus Position Paper From REAL-PANLAR Group on Improvement of Rheumatoid Arthritis Care in Latin America Establishing Centers of Excellence Santos-Moreno, P; Galarza-Maldonado, C; Caballero-Uribe, CV; Cardiel, MH; Massardo, L; Soriano, ER; Olano, JA; Coto, JFD; Pozo, GRD; da Silveira, IG; et al. Article ISI SCOPUS Journal of Clinical Rheumatology (2015)
Recomendaciones sobre el manejo del compromiso renal del lupus eritematoso sistémico: Documento de Consenso de las Sociedades Chilenas de Nefrología y Reumatología Verónica Aguirre; Miriam Alvo; Leopoldo Ardiles; J. Daniel Carpio; Carolina Foster; Annelise Goecke; Roberto Jalil; Loreto Massardo; Sergio Palma; Emilio Roessler; et al. Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2015)
The number of flares patients experience impacts on damage accrual in systemic lupus erythematosus: data from a multiethnic Latin American cohort Ugarte-Gil, MF; Acevedo-Vásquez, E; Alarcon, GS; Pastor-Asurza, CA; Cucho-Venegas, JM; Segami, MI; Wojdyla, D; Soriano, ER; Drenkard, C; Brenol, JC; et al. Article ISI SCOPUS Annals of the Rheumatic Diseases (2015)
Primary cardiac disease in systemic lupus erythematosus patients: protective and risk factors-data from a multi-ethnic Latin American cohort Alarcon, GS; Boggio, G; Hachuel, L; Marcos A.I.; Marcos, JC; Gentiletti, S; Caeiro, F; Sato, EI; Borba, EF; Brenol, JCT; et al. Article ISI SCOPUS RHEUMATOLOGY (2014)
Systemic lupus erythematosus impairs memory cognitive tests not affected by depression Calderon, J; Flores, P; Babul, M; Aguirre, J; Slachevsky, A; Padilla, O; Scoriels, L.; Henríquez, C; Cárcamo, C; González, A; et al. Article ISI SCOPUS LUPUS (2014)
Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients Vicuña, Lucas; Pardo, Evelyn; Curkovic, Cristóbal; Doger, Remziye; Oyanadel, Claudia; Metz, Claudia; Massardo, Loreto; Gonzalez, Alfonso; Soza, Andrea Article ISI SCIELO SCOPUS Biological Research (2013)
Mestizos with systemic lupus erythematosus develop renal disease early while antimalarials retard its appearance: Data from a Latin American cohort Pons-Estel, GJ; Alarcon, GS; Hachuel, L; Boggio, G; Wojdyla, D; Nieto, R; Alvarellos A.; Catoggio, LJ; Guibert-Toledano, M; Sarano J.; et al. Article ISI SCOPUS Lupus (2013)
An update on neuropsychiatric lupus with emphasis in cognitive dysfunction Leon, T; Henríquez, C; Calderon, J; Massardo, L Article ISI REVISTA MEDICA DE CHILE (2012)
Early Rheumatoid Arthritis in Latin America: Low Socioeconomic Status Related to High Disease Activity at Baseline Massardo, L; Wojdyla, D; Galarza-Maldonado C.M.; Laurindo I.M.; Padilla, O; Guibert-Toledano Z.M.; Da Mota L.M.; Montufar R.A.; Lino-Perez L.; Esteva Spinetti M.H.; et al. Article ISI SCOPUS Arthritis Care and Research (2012)
The impact of rural residency on the expression and outcome of systemic lupus erythematosus: data from a multiethnic Latin American cohort Saurit, V; Hachuel, L; Boggio, G; Wojdyla, D; Alfaro-Lozano J.L.; Massardo, L; Esteva Spinetti M.H.; Guibert-Toledano, M; Gomez L.A.R.; Costallat L.T.L.; et al. Article ISI SCOPUS Lupus (2012)
Treatment of Early Rheumatoid Arthritis in a Multinational Inception Cohort of Latin American Patients The GLADAR Experience Wojdyla, D; Saurit, V; Pinto M.R.C.; Cordeiro De Azevedo A.B.; Radominski, SC; Ximenes A.C.; Massardo, L; Ballesteros F.; Rojas-Villarraga A.; Onate R.V.; et al. Article ISI SCOPUS Journal of Clinical Rheumatology (2012)
Common mental disorders and psychological distress in systemic lupus erythematosus are not associated with disease activity Jarpa E.; Babul, M; Calderon, J; GonzÃ¡lez M; Martinez, ME; Bravo-Zehnder, M; Henríquez, C; Jacobelli, S.; Gonzaalez, A; Massardo, L Article ISI SCOPUS Lupus (2011)
Antimalarial Treatment May Have a Time-Dependent Effect on Lupus Survival Shinjo, SK; Bonfa, E; Wojdyla, D; Borba, EF; Scherbarth, HR; Brenol, JCT; Chacón-Díaz, R; Neira, OJ; Berbotto, GA; De La Torre, IG; et al. Article ISI SCOPUS Arthritis and Rheumatism (2010)
Extensive cerebral vein thrombosis as first manifestation of Behcet's disease. Report of one case Lizarazo-Barrera, JC; Jacobelli, S.; Mellado, P; Gonzalez, S; Massardo, L Article ISI REVISTA MEDICA DE CHILE (2010)
Extensive cerebral vein thrombosis as first manifestation of Behçet's disease. Report of one case Trombosis de senos venosos encefálicos como posible primera manifestación de enfermedad de Behçet: Caso clínico Jacobelli, S.; Massardo, L; Mellado, P; Gonzalez, S Article SCOPUS Revista Medica de Chile (2010)
Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation Massardo, L; Metz, C; Pardo E.; Mezzano, V; Babul, M; Jarpa E.; Andre, S; Kaltner, H; Gabius, HJ; Jacobelli, S.; et al. Article ISI SCOPUS LUPUS (2009)
Galectin-8 Induces Apoptosis in Jurkat T Cells by Phosphatidic Acid-mediated ERK1/2 Activation Supported by Protein Kinase A Down-regulation Norambuena, A; Metz, C; Vicuña L.; Silva, A; Pardo E.; Oyanadel, C; Massardo, L; González, A; Soza, A Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Management of Patients With Rheumatoid Arthritis in Latin America A Consensus Position Paper From Pan-American League of Associations of Rheumatology and Grupo Latino Americano De Estudio de Artritis Reumatoide Massardo, L; Suarez-Almazor, ME; Cardiel, MH; Nava, A; Levy, RA; Laurindo, I; Soriano, ER; Acevedo-Vazquez, E; Millan, A; Pineda-Villasenor, C; et al. Article ISI SCOPUS JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2009)
Early rheumatoid arthritis Artritis reumatoide temprana Massardo, L Article SCOPUS REVISTA MEDICA DE CHILE (2008)
Use of rituximab for the treatment of rheumatoid arthritis: the Latin American context Soriano, ER; Galarza-Maldonado, C; Cardiel, MH; Pons-Estel, BA; Massardo, L; Caballero-, CV; Achurra-Castillo, AF; Barile-Fabris, LA; Chavez-Corrales, J; Diaz-Coto, JF; et al. Article ISI SCOPUS RHEUMATOLOGY (2008)
Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis Matus, S; Burgos, PV; Bravo-Zehnder, M; Kraft, R.; Farías, P; Barros, LF; Torrealba, F.; Massardo, L; Jacobelli, S.; González, A Article ISI SCOPUS JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Accuracy of anti-ribosomal P protein antibody testing for the diagnosis of neuropsychiatric systemic lupus erythematosus - An international meta-analysis Karassa, FB; Afeltra, A; Ambrozic, A; Chang, DM; De Keyser, F; Doria, A; Galeazzi, M; Hirohata, S; Hoffman, IEA; Inanc, M; et al. Article ISI SCOPUS ARTHRITIS AND RHEUMATISM (2006)
Antibodies against galectin-8 in patients with systemic lupus erythematosus Pardo E.; Cárcamo, C; Massardo, L; Mezzano, V; Jacobelli, S.; González, A; Soza, A Article ISI REVISTA MEDICA DE CHILE (2006)
Autoanticuerpos anti-galectina-8 en pacientes con lupus eritematoso sistémico Pardo, Evelyn; Cárcamo, Claudia; Massardo, Loreto; Mezzano, Veronica; Jacobelli, Sergio; Gonzalez, Alfonso; Soza G, Andrea Article SCIELO REVISTA MEDICA DE CHILE (2006)
Circulating platelet-derived microparticles in systemic lupus erythematosus - Association with increased thrombin generation and procoagulant state Pereira, J; Alfaro G.; Goycoolea, M; Quiroga T.; Ocqueteau, M; Massardo, L; Perez, C; Sáez, C; Panes O.; Matus, V.; et al. Article ISI SCOPUS THROMBOSIS AND HAEMOSTASIS (2006)
Circulating Platelet-Derived Microparticles in Systemic Lupus Erythematosus. Association With Increased Thrombin Generation and Procoagulant State Pereira Jaime, Alfaro Gino, Goycolea Manuela, Quiroga Teresa, Ocqueteau Mauricio, Massardo Loreto, Pérez Carol. Sáez Claudia, Panes Olga, Matus Valeria, Mezzano Diego Article THROMBOSIS AND HAEMOSTASIS (2006)
Effectiveness of infliximab in patients with Behcet syndrome and severe uveoretinitis. Report of five cases Merino, G; Varas, G; Díaz, G; Gutiérrez, M; Massardo, L; Pacheco, D.; Villarroel, F; Cuchacovich M. Article ISI REVISTA MEDICA DE CHILE (2006)
Galectin-8 binds specific beta 1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells Cárcamo, C; Pardo E.; Oyanadel, C; Bravo-Zehnder, M; Bull, P; Cáceres, M; Martínez, J; Massardo, L; Jacobelli, S.; González, A; et al. Article ISI SCOPUS EXPERIMENTAL CELL RESEARCH (2006)
Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort Alarcon-Segovia, D; Alarcón-Riquelme, ME; Cardiel, MH; Caeiro, F; Massardo, L; Villa, AR; Pons-Estel, BA Article ISI SCOPUS ARTHRITIS AND RHEUMATISM (2005)
Effectiveness of infliximab in patients with inflammatory arthritis refractory to conventional treatment Labarca, C; Massardo, L; Garcia, PI; Jacobelli, S. Article ISI REVISTA MEDICA DE CHILE (2003)
Outcome of Chilean Patients with Lupus Nephritis and Response to Intravenous Cyclophosphamide Vel??squez, Ximena; Verdejo, Ulises; Mart??nez, Mar??a Eugenia; Arriagada, Sonia; Rosenberg, Helmar; Valdivieso, Andr??s; Jacobelli, Sergio Article JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2003)
Paget disease of bone. Report of 15 cases Gonzalez, G; Brusco, F; Arteaga, E; Rodriguez, J; Jacobelli, S.; Massardo, L; Ortiz, C; Contreras, O Article ISI REVISTA MEDICA DE CHILE (2003)
A population based assessment of the use of orthopedic surgery in patients with rheumatoid arthritis Massardo, L, Gabriel SE, Crowson Cs, O'Fallon WM, Matteson EL Article WOS CORE COLLECTION ISI JOURNAL OF RHEUMATOLOGY (2002)
Antiribosomal P protein antibodies in Chilean SLE patients: no association with renal disease Massardo, L; Burgos, P; Martinez, ME; Pérez, R.; Calvo, M; Barros, M; González, A; Jacobelli, S. Article ISI SCOPUS LUPUS (2002)
The presence of the HLA-DRB1 shared epitope correlates with erosive disease in Chilean patients with rheumatoid arthritis Massardo, L; Gareca, N; Cartes, MA; Cervilla, V.; González, A; Jacobelli, S. Article ISI SCOPUS RHEUMATOLOGY (2002)
Prevalence and isotype distribution of antiphospholipid antibodies in Chilean patients with systemic lupus erythematosus (SLE) Aguirre V.; Cuchacovich, R; Barria, L; Aris, H; Trejo, C; Massardo, L; Pasten, R; Espinoza, L Article ISI LUPUS (2001)
Increased expression of c-rel, from the NF-?B/Rel family, in T cells from patients with systemic lupus erythematosus Burgos, P; Bull, P; Metz, C; Pincheira, R; Massardo, L; Errazuriz, C; Jacobelli, S.; González, A; Bono, MR Article SCOPUS JOURNAL OF RHEUMATOLOGY (2000)
Increased expression of c-rel, from the NF-kappa B/Rel family, in T cells from patients with systemic lupus erythematosus Burgos, P; Metz, C; Bull, P; Pincheira, R; Massardo, L; Errazuriz, C; Jacobelli, S.; González, A Article ISI JOURNAL OF RHEUMATOLOGY (2000)
Influence of the HLA-DRbeta shared epitope on susceptibility to and clinical expression of rheumatoid arthritis in Chilean patients Nicovani, S.; Cervilla, V.; Lanchbury, J. S; Jacobelli, S. Article ANNALS OF THE RHEUMATIC DISEASES (1997)
Occasional Series: Lupus Around the World The Chilean experience of systemic lupus erythematosus Article LUPUS (1996)
High-Dose Intravenous Methylprednisolone Therapy Associated with Osteonecrosis in Patients with Systemic Lupus Erythematosus Jacobelli, Sergio; Leissner, Mauricio Article LUPUS (1992)
Novel genetic markers of rheumatoid arthritis in chilean patients, by dr serotyping and restriction fragment length polymorphism analysis Bull, Paulina; Jacobelli, Sergio Article Arthritis Rheumatism (1992)
Weak association between HLA-DR4 and rheumatoid arthritis in Chilean patients. Marchetti, R Article ANNALS OF THE RHEUMATIC DISEASES (1990)
Osteoarthritis of the knee joint: an eight year prospective study. Watt, I; Cushnaghan, J; Dieppe, P Article ANNALS OF THE RHEUMATIC DISEASES (1989)
Inspiratory muscle dysfunction and unexplained dyspnea in systemic lupus erythematosus Jacobelli, Sergio; Moreno, Rodrigo; Lisboa, Carmen Article Arthritis Rheumatism (1985)


Factors Predictive of Flares in Systemic Lupus Erythematosus Patients: Data from a Multiethnic Latin American Cohort Ugarte-Gil, MF; Wojdyla, D; Pastor-Asurza, CA; Gamboa-Cardenas, RV; Acevedo-Vasquez, EM; Bonfa, E; Massardo, L; Pascual-Ramos, V; Alarcon, GS; Pons-Estel, BA Abstract ISI CLINICAL AND EXPERIMENTAL RHEUMATOLOGY (2015)
Cognitive impairment in lupus erythematosus: contribution of depression and intrinsic disease factors Calderon, J; Flores, P; Babul, M; Aguirre, JM; Henríquez, C; Padilla, O; Massardo, L Abstract ISI PSYCHOTHERAPY AND PSYCHOSOMATICS (2013)
Hemorrhagic emergency due to intrahepatic aneurism rupture in a patient with Polyateritis Nodosa after long time of episodic fever: A case report Silva, F; Cisternas,M; Maguida, G; Ruiz, MI; Diaz, P; Gonzalez, S; Martínez, J; Meneses L.; Massardo, L Abstract ISI PRESSE MEDICALE (2013)
THE MEANING OF LIVING WITH SYSTEMIC LUPUS ERYTHEMATOSUS: QUALITATIVE STUDY IN CHILEAN WOMEN Henríquez, C; Peláez-Ballestas, I; Massardo, L; Rivera, MS Abstract ISI ANNALS OF THE RHEUMATIC DISEASES (2013)
Use of rituximab in Hispanic patients with severe ANCA associated vasculitis: A 6 years experience in a tertiary centre in Chile Silva, F; Massardo, L; Mimica, M; Pastenes, P; Cisternas,M; Radrigan, F; Gutiérrez, M Abstract ISI PRESSE MEDICALE (2013)
Anti NMDAR and Anti-P/NSPA Antibodies Contribute to Cognitive Dysfunction in Lupus Patients. Massardo, L; Flores, P; Calderon, J; Bravo-Zehnder, M; Jurado, A; Henríquez, C; Padilla, O; Babul, M; Slachevsky, A; Jacobelli, S.; et al. Abstract ISI ARTHRITIS AND RHEUMATISM (2011)
Anti-P Autoantibodies Enhance Cytosolic Calcium and Neurotransmission in Hippocampal Neurons by Cross-Reacting with Cell Surface NSPA Segovia-Miranda, F; Parodi, J; Serrano, F; Escobedo, N; Bravo-Zehnder, M; Larrain, J; Massardo, L; Valenzuela, D; Zamorano, P; Inestrosa, N; et al. Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2011)
Cognitive impairment in Chilean patients with systemic lupus erythematosus (sle) is not related to depression Calderon, J; GonzÃ¡lez M; Flores, P; Henríquez, C; Babul, M; Padilla, O; Slachevsky, A; Massardo, L Abstract ISI JOURNAL OF PSYCHOSOMATIC RESEARCH (2011)
Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline Massardo, L; Pons-Estel, BA; Cardiel, MH; Galarza-Maldonado, C; Sacnun, MP; Soriano, ER; Laurindo, I; Acevedo-Vasquez, EM; Caballero-Uribe, CV; Padilla, O; et al. Abstract ISI ARTHRITIS AND RHEUMATISM (2011)
Latinamerican Survey on the Use of Glucocorticoids in Rheumatoid Arthritis. Patients' and Rheumatologists' Perspective Cardiel M.; Maldonado, CG; Massardo, L; Montúfar, R; Santos-Moreno, P; Pineda, C; Saaibi, D; Toloza, S; Garcia-Carrasco, M; Cairoli, E; et al. Abstract ISI JOURNAL OF RHEUMATOLOGY (2011)
APPLIANCE OF A HEALTH CARE REFORM IN CHILE OFFERING MEDICAL BENEFITS FOR RHEUMATOID ARTHRITIS (RA) Durán, J; Leppe, J; Valdivia, G; Llanos, L; Trivino, M; Massardo, L; Torche, A; Jacobelli, S.; Gutiérrez, M Abstract ISI JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2010)
HEALTH RELATED VARIABLES IN RHEUMATOID ARTHRITIS (RA) PATIENTS TREATED IN DIFFERENT HEALTH CARE SETTINGS (DHCS); SANTIAGO DE CHILE Leppe, J; Valdivia, G; Durán, J; Llanos, L; Trivino, M; Massardo, L; Torche, A; Jacobelli, S.; Gutiérrez, M Abstract ISI JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2010)
INFLUENCE OF CLINICAL AND SOCIOECONOMIC VARIABLES ON QUALITY OF LIFE OF RHEUMATOID ARTHRITIS PATIENTS TREATED IN DIFFERENT HEALTH CARE SETTINGS (DHCS) Leppe, J; Valdivia, G; Durán, J; Llanos, L; Trivino, M; Massardo, L; Torche, A; Jacobelli, S.; Gutiérrez, M Abstract ISI JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2010)
Anti-P antibodies impair memory in mice Bravo-Zehnder, M; Achurra P; Toledo, E; Segovia, F; Inestrosa, N; Massardo, L; González, A Abstract ISI ARTHRITIS AND RHEUMATISM (2008)
Detection of bone erosions in rheumatoid arthritis wrist and meta-carpophalangeal joints: A comparison of ultrasonography, computed tomography and magnetic resonance imaging. Vargas, JI; Ortega, C; Burdiles, A; Contreras, O; Massardo, L Abstract ISI ARTHRITIS AND RHEUMATISM (2006)
Autoantibodies against galectin-8 block adhesion and lamellipodia formation induced by galectin-8 in Jurkat cells Cárcamo, C; Soza, A; Pardo E.; Bull, P; Massardo, L; Jacobelli, S.; González, A Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2004)
Loss of platelet membrane phospholipid asymmetry in systemic lupus erythematosus: Association with disease activity and hypercoagulable state. Pereira, J; Quiroga T.; Massardo, L; Perez, C; Alfaro G.; Ocqueteau, M; Panes O.; Mezzano, D Abstract ISI BLOOD (2004)
Autoantibodies against ribosomal P proteins recognize a novel surface protein in brain neurons Burgos, P; Matus, S; Torrealba, F.; Massardo, L; Jacobelli, S.; González, A Abstract ISI ARTHRITIS AND RHEUMATISM (2003)
Blocking autoantibodies against the dopamine transporter in a SLE patient with psychosis Matus, S; Burgos, P; Torres, GE; Caron, MG; Massardo, L; Gutiérrez, M; Jacobelli, S.; González, A Abstract ISI ARTHRITIS AND RHEUMATISM (2003)
Novel proteins of the synaptic region are autoantigens associated with lupic neuropsychiatric manifestations Burgos, P; Otero, C; De La Fuente E.; Massardo, L; Jacobelli, S.; González, A Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2001)


Lupus eritematoso sistémico y psiquiatría •Calderón J y Massardo L; Calderon, Jorge, González Matías BookSection (2016)
Síndrome metabólico en Lupus eritematoso sistémico. Llanos C, Massardo L; Battagliotti C, Gentiletti A, PonsEstel B, Berbotto G y Pons-Estel G. BookSection (2013)
Rheumatoid Arthritis. • Galarza-Maldonado C, Massardo L, Pons-Estel B, and Cardiel MH; Shoenfeld, Cervera, Gerswhin BookSection (2008)


Trombosis de senos venosos encefálicos como posible primera manifestación de enfermedad de Behçet: Caso clínico LIZARAZO-BARRERA, JUAN CARLOS; Jacobelli, Sergio; Mellado, Patricio; Gonzalez, Sergio; Massardo, Loreto CaseReport SCIELO REVISTA MEDICA DE CHILE (2010)
Eficacia del infliximab en pacientes con síndrome de Behçet portadores de úveo-retinitis grave Merino, Guillermo; Varas, Gonzalo; Diaz, Gonzalo; Gutierrez, Miguel; Massardo, Loreto; Pacheco, Daniel; Villarroel, Francisco; Cuchacovich, Miguel CaseReport SCIELO REVISTA MEDICA DE CHILE (2006)


Clinical predictors of remission and low disease activity in Latin American early rheumatoid arthritis: data from the GLADAR cohort (vol 38, pg 2737, 2019) Radominski, SC; Ballesteros F. Errata ISI SCOPUS CLINICAL RHEUMATOLOGY (2019)


Education for patients with rheumatoid arthritis in Latin America and the Caribbean Khoury V.; Kourilovitch, M; Massardo, L Review ISI SCOPUS Clinical Rheumatology (2015)
Lupus in Latin-American patients: lessons from the GLADEL cohort Pons-Estel, GJ; Catoggio, LJ; Cardiel, MH; Bonfa, E; Caeiro, F; Sato, E; Massardo, L; Molina-Restrepo, JF; Toledano, MG; Barile-Fabris, LA; et al. Review ISI SCOPUS Lupus (2015)
Actualización en lupus neuro-psiquiátrico con énfasis en déficit cognitivo Tomás León; Carla Henríquez; Jorge Calderón; Loreto Massardo Review SCIELO SCOPUS REVISTA MEDICA DE CHILE (2012)
Artritis reumatoide temprana Massardo, Loreto Review SCIELO REVISTA MEDICA DE CHILE (2008)
Early rheumatoid arthritis Massardo, L Review ISI REVISTA MEDICA DE CHILE (2008)

Alejandra Alvarez

Full professor

Cell and Molecular Biology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Jaime Pereira

Jefe

Hematología-Oncología

ESCUELA DE MEDICINA, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Olga Panes

Technical Director/ Associated Research

Hematology-Oncology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Diego Mezzano

Director

Hematology-Oncology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Valeria Matus

Associate Researcher

Hematology-Oncology

P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

Miriam Alvo

jefa de sección

de medicina

HOSPITAL CLÍNICO U. DE CHILE

Santiago, Chile

Juan Agustín Larraín

Profesor Titular

Biologia Celular y Molecular

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Sergio González

FACULTAD DE MEDICINA. PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Patricia Burgos

Associate Professor Programa de Doctorado en Biología Celular y Biomedicina CEBICEM

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

Oslando Padilla

Estadístico

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

Andrea Soza

Profesor Asociado

Medicina y Ciencia

Universidad San Sebastián

Santiago, Chile

CLAUDIA CARCAMO

Profesor Asociado

neurology

PONTIFICIA UNIVERSIDADA CATÓLICA DE CHILE. DEPARTAMENTO DE NEUROLOGÍA

Santiago, Chile

Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

Brigitte van Zundert

Full Professor

UNIVERSIDAD ANDRÉS BELLO, CENTRO DE INVESTIGACIONES BIOMÉDICAS

Santiago, Chile

Evelyn Pardo

Investigadora Independiente

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

SANTIAGO , Chile

Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

MARIO CALVO

Profesor Asociado

Instituto de Medicina

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

Roxana Pincheira

Full Professor

Bioquímica y Biología Celular

Universidad de Concepcion

Concepción, Chile

PEDRO ZAMORANO

Profesor Asociado

Depto Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Monica Caceres

Profesor asociado

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

Jorge Parodi

Director de laboratorio

Tonalli Ltda

Temuco, Chile

Jorge Martinez

Profesor Titular

Laboratorio de Biología Celular

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE ALIMENTOS (INTA), UNIVERSIDAD DE CHILE

Santiago, Chile

Leopoldo Ardiles

Profesor Titular

Medicina

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Gonzalo Valdivia

Division Head, Full Professor

Medical School

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Claudia Oyanadel

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Omar Porras

Associate professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

Andrea Slachevsky

Associate Professor

ICBM

UNIVERSIDAD DE CHILE

Chile, Chile

Claudia Saez

Associate Professor

Hematology-Oncology

Pontificia Universidad Católica de Chile

Santiago, Chile

Jaime Leppe

Coordinador de Investigación Carrera de Kinesiología

Universidad del Desarrollo

Santiago, Chile

Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Noelia Escobedo

Profesor Asistente

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Talca, Chile

Maria Matus

Principal Investigator

Fundacion Ciencia & Vida

Santiago, Chile

Pablo Achurra

Cirujano Digestivo/ Instructor Adjunto

Cirugía Digestiva

Pontificia Universidad Católica de Chile

Santiago, Chile

Oscar Neira

Medico internista y reumatólogo

Medicina oriente

Hospital del Salvador

Santiago, Chile

Fabián Segovia

Associate professor

Department of Cell Biology

Universidad de Concepción

Concepción, Chile

MATIAS GONZALEZ

Miguel Gutierrez

jefe servicio medicina

medicina

hospital naval almirante nef

viña del mar, Chile

TOMAS LEON

Psiquiatra

Clinica de Memoria y Neuropsiquiatría

santiago , Chile

Claudia Metz

Docente Investigador

Universidad San Sebastián

Santiago, Chile

Maria Massardo

Docente Investigador

Medicina

Universidad San Sebastián

Santiago, Chile

Ana Guzman

MÉDICO JEFE LABORATORIO

LABORATORIO CLÍNICO

PONTIFICIA UNIVERSIDAD CATÓLICA

SANTAIGO, Chile

Milena Mimica

Profesor Instructor

Facultad de Medicina

Universidad San Sebastián

Santiago de Chile, Chile

Maria Loreto Massardo Vega

Líneas de Investigación

Educación

Médico-Cirujano, UNIVERSIDAD DE CHILE. Chile, 1979

Reumatología, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1982

Rheumatology, University of Bristol. Reino Unido, 1988

Experiencia Académica

Profesor titular Full Time

Docente Investigador Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

PANLAR-Merck Rheumatology Prize for LatinAmerican Rheumatologists 2002

Premio Academia de Medicina 2012

Premio Conferencia Sociedad Médica de Santiago

Article (62)

Abstract (20)

BookSection (3)

CaseReport (2)

Errata (1)

Review (5)