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Valeria Muriel Matus Ritter

Associate Researcher

P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Disfuncion Endotelial; Trombosis y hemostasia. ParticipaciÃ³n de plaquetas y endotelio en fenÃ³menos pro-coagulantes; ComunicaciÃ³n Intercelular; Desarrollo de vacunas bacterianas; Resistencia a antimicrobianos en Enterobacterias; Mecanismos de virulencia de bacterias patÃ³genas; FISIOLOGÃƒÂA Y Â FISIOPATOLOGIA PLAQUETARIA; BIOLOGIA MOLECULAR DE PLAQUETAS; PLAQUETAS E INMUNIDAD INNATA; FisiologÃa y FisiopatologÃa de las plaquetas; FisiopatologÃa de las enfermedades trombÃ³ticas; DaÃ±o vascular asociado a uso de cocaÃna

Bioquímico, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1994
Biol. Sc. Molecular Biology, P. U. Católica de Chile. Chile, 2002

Associate Researcher Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicine

Santiago, Chile

2006 - At present

Associate Researcher Full Time

P. U. Católica de Chile

Santiago, Chile

2002 - At present
Project Manager Part Time

P. U. Católica de Chile

Santiago, Chile

2006 - 2017

“Asociación física y funcional entre GPVI y el factor tisular en plaquetas humanas”. José Guillermo Valenzuela. Tesis de Pregrado, Bioquímica. 2012 P. Universidad Católica de Chile. Tutor.

“Activación de plaquetas humanas por bacterias Gram negativas o LPS: influencia sobre su actividad procoagulante”. Constanza Fabiola González González. Experiencia Profesional Dirigida, conducente al título de Biólogo, mención en Bioprocesos, P. U. Católica de Chile. 2013. Tutor.

“Interacción Plaqueta-Bacteria TLR4/LPS”. Gustavo Soto, Seminario de Investigación, Bioquímica P. U. Católica de Chile, 1er semestre 2013.

“Interacción de Plaquetas Humanas con E. coli, incrementa su actividad procoagulante”. Tesis de Pregrado, Bioquímica. 2014 P. Universidad Católica de Chile. Tutor

Premio Dr. German Ducach Grinberg 2014

Sociedad Médica de Chile

Chile, 2014

PREMIO DOCTOR GERMAN DUCACH GRINBERG premio al mejor trabajo publicado en HEMATOLOGIA CLÍNICA DE ADULTOS.


An adenine insertion in exon 6 of human GP6 generates a truncated protein associated with a bleeding disorder in four Chilean families Matus, V.; Valenzuela, G; Saez CG; Hidalgo, P.; Lagos, M; Aranda, E; Panes O.; Pereira J.; Pillois, X; Nurden, AT; Mezzano D. Article ISI SCOPUS Journal of Thrombosis and Haemostasis (2013)
Clot lysis time in platelet-rich plasma: Method assessment, comparison with assays in platelet-free and platelet-poor plasmas, and response to tranexamic acid Panes O.; Padilla, O; Matus, V.; Sez C.G.; Berkovits, A; Pereira J.; Mezzano D. Article ISI SCOPUS Platelets (2012)
Diagnosis of mild platelet function disorders. Reliability and usefulness of light transmission platelet aggregation and serotonin secretion assays Quiroga T.; Goycoolea M.; Matus, V.; Zúñiga P; Martínez C; Garrido M.; Aranda, E; Leighton F.; Panes O.; Pereira J.; Mezzano D. Article ISI SCOPUS BRITISH JOURNAL OF HAEMATOLOGY (2009)
Platelet Tissue Factor: Fast and Specific Clotting Activation Pathway Mediated by VWF-GPIba Interaction and Platelet Membrane FVII. Human Platelets Contain All the Components for Assembling the Prothrombinase Complex and Their Procoagulant Function Is Ind Panes O.; Matus, V.; Saaez, CG; Pereira J.; Mezzano D. Article BLOOD (2009)
Procarboxypeptidase U (TAFI) and the Thr325Ile proCPU polymorphism in patients with hereditary mucocutaneous hemorrhages Matus, V.; Willemse, J; Quiroga T.; Goycoolea M.; Aranda, E; Panes O.; Pereira J.; Hendriks, D; Mezzano D. Article ISI SCOPUS CLINICA CHIMICA ACTA (2009)
Tissue factor storage, synthesis and function in normal and activated human platelets Mezzano D.; Matus, V.; Saez CG; Pereira J.; Panes O. Article ISI THROMBOSIS RESEARCH (2008)
Human platelets synthesize and express functional tissue factor Panes O.; Matus, V.; Saez CG; Quiroga T.; Pereira J.; Mezzano D. Article ISI SCOPUS BLOOD (2007)
Influence of the Thr325Ile polymorphism on procarboxypeptidase U (thrombin-activable fibrinolysis inhibitor) activity-based assays [7] Willemse J.L.; Heylen, E; Hendriks D.F.; Matus, V.; Mezzano D. Article JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2007)
Circulating platelet-derived microparticles in systemic lupus erythematosus - Association with increased thrombin generation and procoagulant state Pereira J.; Alfaro G.; Goycoolea M.; Quiroga T.; Ocqueteau, M; Massardo, L; Pérez, C.; Sáez C.; Panes O.; Matus, V.; Mezzano D. Article ISI SCOPUS THROMBOSIS AND HAEMOSTASIS (2006)
Efficient degradation of 2,4,6-trichlorophenol requires a set of catabolic genes related to tcp genes from Ralstonia eutropha JMP134(pJP4) Matus, V.; Sánchez MA; Martínez M; Gonzalez, B. Article ISI SCOPUS APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Poly-beta-hydroxyalkanoates consumption during degradation of 2,4,6-trichlorophenol by Sphingopyxis chilensis S37 Godoy FA; Bunster, M; Matus, V.; Aranda C.; Gonzalez, B.; Martinez, MA. Article ISI SCOPUS LETTERS IN APPLIED MICROBIOLOGY (2003)
Degradation of 2,4,6-trichlorophenol via chlorohydroxyquinol in Ralstonia eutropha JMP134 and JMP222 Padilla L.; Matus, V.; Zenteno, P; Gonzalez, B. Article ISI SCOPUS JOURNAL OF BASIC MICROBIOLOGY (2000)
Microbial mineralization of 2,4,5-trichlorophenol in soil Matus, V.; Vásquez M; Vicente, M; Gonzalez, B. Article ENVIRONMENTAL SCIENCE AND TECHNOLOGY (1996)


EVALUATION OF CLOT LYSIS TIME WITH PLATELETS: CORRELATION WITH CARDIOVASCULAR RISK MARKERS Panes O.; Aranda, E; Matus, V.; Acevedo M.; Pereira J.; Mezzano D. Abstract Clinical Chemistry and Laboratory Medicine (2011)
Tissue factor pathway inhibitor (TFPI) and tissue factor (TF) co-localize in lipid rafts of platelet membranes: mechanism to inhibit platelet procoagulant (PCA) activity? Olga, P; González C; Matus, V.; Pereira J.; Mezzano D. Abstract JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2011)
Clot lysis time (CLT) of PRP and PPP in hypercholesterolemia. Effect of atorvastatin and relationships with inflammatory markers Mezzano D.; Acevedo M.; Pereira J.; Matus, V.; Panes O. Abstract JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2010)
Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins Panes O.; Acevedo M.; Matus, V.; Saez CG; Pereira J.; Mezzano D. Abstract BLOOD (2010)
Platelet Tissue Factor: Expression of Pro-Coagulant Activity depends on Gpib alpha Activation and Signaling through Lyn-Mediated Phosphorylation. A Platelet-Based Model of Hemostasis Panes O.; Ibarra P.; Matus, V.; Saez CG; Pereira J.; Mezzano D. Abstract BLOOD (2008)
Human platelet tissue factor is localized in lipid rafts and is associated with GPIb-IX-V complex in the membrane: Association between adhesive and procoagulant activities of platelets. Panes O.; Matus, V.; Saez CG; Garate, A.; Pereira J.; Mezzano D. Abstract BLOOD (2006)


Influence of the Thr325Ile polymorphism on procarboxypeptidase U (thrombin-activable fibrinolysis inhibitor) activity-based assays Willemse, JL; Matus, V.; Heylen, E; Mezzano D.; Hendriks, DF Letter ISI JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2007)