Man

Valeria Muriel Matus Ritter

Associate Researcher

P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Líneas de Investigación


Disfuncion Endotelial; Trombosis y hemostasia. Participación de plaquetas y endotelio en fenómenos pro-coagulantes; Comunicación Intercelular; Desarrollo de vacunas bacterianas; Resistencia a antimicrobianos en Enterobacterias; Mecanismos de virulencia de bacterias patógenas; FISIOLOGÍA Y  FISIOPATOLOGIA PLAQUETARIA; BIOLOGIA MOLECULAR DE PLAQUETAS; PLAQUETAS E INMUNIDAD INNATA; Fisiología y Fisiopatología de las plaquetas; Fisiopatología de las enfermedades trombóticas; Daño vascular asociado a uso de cocaína

Educación

  •  Bioquímico, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1994
  •  Biol. Sc. Molecular Biology, P. U. Católica de Chile. Chile, 2002

Experiencia Académica

  •   Associate Researcher Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicine

    Santiago, Chile

    2006 - At present

Experiencia Profesional

  •   Associate Researcher Full Time

    P. U. Católica de Chile

    Santiago, Chile

    2002 - At present

  •   Project Manager Part Time

    P. U. Católica de Chile

    Santiago, Chile

    2006 - 2017

Formación de Capital Humano


“Asociación física y funcional entre GPVI y el factor tisular en plaquetas humanas”. José Guillermo Valenzuela. Tesis de Pregrado, Bioquímica. 2012 P. Universidad Católica de Chile. Tutor.

“Activación de plaquetas humanas por bacterias Gram negativas o LPS: influencia sobre su actividad procoagulante”. Constanza Fabiola González González. Experiencia Profesional Dirigida, conducente al título de Biólogo, mención en Bioprocesos, P. U. Católica de Chile. 2013. Tutor.

“Interacción Plaqueta-Bacteria TLR4/LPS”. Gustavo Soto, Seminario de Investigación, Bioquímica P. U. Católica de Chile, 1er semestre 2013.

“Interacción de Plaquetas Humanas con E. coli, incrementa su actividad procoagulante”. Tesis de Pregrado, Bioquímica. 2014 P. Universidad Católica de Chile. Tutor


Premios y Distinciones

  •   Premio Dr. German Ducach Grinberg 2014

    Sociedad Médica de Chile

    Chile, 2014

    PREMIO DOCTOR GERMAN DUCACH GRINBERG premio al mejor trabajo publicado en HEMATOLOGIA CLÍNICA DE ADULTOS.


 

Article (13)

An adenine insertion in exon 6 of human GP6 generates a truncated protein associated with a bleeding disorder in four Chilean families
Clot lysis time in platelet-rich plasma: Method assessment, comparison with assays in platelet-free and platelet-poor plasmas, and response to tranexamic acid
Diagnosis of mild platelet function disorders. Reliability and usefulness of light transmission platelet aggregation and serotonin secretion assays
Platelet Tissue Factor: Fast and Specific Clotting Activation Pathway Mediated by VWF-GPIba Interaction and Platelet Membrane FVII. Human Platelets Contain All the Components for Assembling the Prothrombinase Complex and Their Procoagulant Function Is Ind
Procarboxypeptidase U (TAFI) and the Thr325Ile proCPU polymorphism in patients with hereditary mucocutaneous hemorrhages
Tissue factor storage, synthesis and function in normal and activated human platelets
Human platelets synthesize and express functional tissue factor
Influence of the Thr325Ile polymorphism on procarboxypeptidase U (thrombin-activable fibrinolysis inhibitor) activity-based assays [7]
Circulating platelet-derived microparticles in systemic lupus erythematosus - Association with increased thrombin generation and procoagulant state
Efficient degradation of 2,4,6-trichlorophenol requires a set of catabolic genes related to tcp genes from Ralstonia eutropha JMP134(pJP4)
Poly-beta-hydroxyalkanoates consumption during degradation of 2,4,6-trichlorophenol by Sphingopyxis chilensis S37
Degradation of 2,4,6-trichlorophenol via chlorohydroxyquinol in Ralstonia eutropha JMP134 and JMP222
Microbial mineralization of 2,4,5-trichlorophenol in soil

Abstract (6)

EVALUATION OF CLOT LYSIS TIME WITH PLATELETS: CORRELATION WITH CARDIOVASCULAR RISK MARKERS
Tissue factor pathway inhibitor (TFPI) and tissue factor (TF) co-localize in lipid rafts of platelet membranes: mechanism to inhibit platelet procoagulant (PCA) activity?
Clot lysis time (CLT) of PRP and PPP in hypercholesterolemia. Effect of atorvastatin and relationships with inflammatory markers
Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins
Platelet Tissue Factor: Expression of Pro-Coagulant Activity depends on Gpib alpha Activation and Signaling through Lyn-Mediated Phosphorylation. A Platelet-Based Model of Hemostasis
Human platelet tissue factor is localized in lipid rafts and is associated with GPIb-IX-V complex in the membrane: Association between adhesive and procoagulant activities of platelets.

Letter (1)

Influence of the Thr325Ile polymorphism on procarboxypeptidase U (thrombin-activable fibrinolysis inhibitor) activity-based assays
31
Valeria Matus

Associate Researcher

Hematology-Oncology

P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

19
Olga Panes

Technical Director/ Associated Research

Hematology-Oncology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

17
Diego Mezzano

Director

Hematology-Oncology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

14
Jaime Pereira

Jefe

Hematología-Oncología

ESCUELA DE MEDICINA, PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

6
Bernardo González

Full Professor

UNIVERSIDAD ADOLFO IBAÑEZ

Santiago, Chile

4
Eduardo Aranda

Biochemist

Hematology

P. UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

3
MONICA ACEVEDO

Titular Professor

Division of Cardiovascular Diseases

P. UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

3
Miguel Martinez

Professor Titular

Microbiologia

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

3
Claudia Saez

Associate Professor

Hematology-Oncology

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Marta Cecilia Bunster

DIRECTORA

Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
Carlos Aranda

Académico

Ciencias Biológicas y Biodiversidad

Universidad de Los Lagos

Osorno, Chile

1
Felix Godoy

Profesor Asociado

Universidad de Los Lagos

Puerto Montt, Chile

1
Alejandro Berkovits

MEDICO

LABORATORIO CLINICO

CLINICA ALEMANA DE SANTIAGO

SANTIAGO, Chile

1
Oslando Padilla

Estadístico

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Pamela Zúñiga

Profesor Asociado

Pediatria

Pontificia Universidad Católica de Chile

Santiago , Chile

1
Maria Massardo

Docente Investigador

Medicina

Universidad San Sebastián

Santiago, Chile