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SERGIO ALEJANDRO LAVANDERO GONZALEZ

Director

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1. Transducción de señales en sistema cardiovascular. 2. Cardiomiopatías y diabetes. 3. Metabolismo mitocondrial. 4. Comunicación inter-organelar. 5. Angiotensina-(1-9). 6. Enfermedades cardiovasculares

Bioquimica, UNIVERSIDAD DE CHILE. Chile, 1993

Adjunct Professor Other

UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS

Dallas, Estados Unidos

2014 - At present
Profesor Titular Full Time

UNIVERSIDAD DE CHILE

Ciencias Quimicas y Farmaceuticas

Santiago, Chile

1985 - At present
Profesor Titular Part Time

UNIVERSIDAD DE CHILE

Medicina

Santiago, Chile

2000 - At present
Visiting Professor Other

UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER

Dallas, Estados Unidos

2010 - 2014

Ayudante Full Time

UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

Santiago, Chile

1989 - 1990
Instructor Full Time

UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

Santaigo, Chile

1985 - 1999
Profesor Asistente Full Time

UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

Santiago, Chile

1991 - 1995
Profesor Asociado Full Time

UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

Santiago, Chile

1995 - 2000


Effects of Trimetazidine on Right Ventricular Function and Ventricular Remodeling in Patients with Pulmonary Artery Hypertension: A Randomised Controlled Trial Verdejo Hugo E.; Rojas, Adolfo; López, Camila; Baraona, Fernando; Gabrielli, Luigi; Maracaja-Coutinho, Vinicius; Chiong M.; Castro, Pablo F.; Lavandero S. Article Journal of Clinical Medicine (2023)
Endothelial activation impairs the function of small extracellular vesicles Herrera, Nicolas; Zuniga-Cuevas, Ursula; Ramirez, Andres; Norambuena, Ignacio; Venegas-Zamora, Leslye; Troncoso, Mayarling Francisca; Hernandez, Alejandra; Sanchez, Gina; Pedrozo, Zully; Riquelme, Jaime; Lavandero S. Article FRONTIERS IN PHARMACOLOGY (2023)
Methods for studying primary cilia in heart tissue after ischemia-reperfusion injury Kretschmar, Catalina; Hernández-Cáceres, María Paz; Reyes, Montserrat; Pena, Daniel; Garcia, Camila; Troncoso R.; Diaz, Francisco; Budini, Mauricio; Morselli, Eugenia; Riquelme, Jaime; Hill, Joseph A; Criollo, Alfredo; Lavandero S. Article CILIA, PT B (2023)
Myristate induces mitochondrial fragmentation and cardiomyocyte hypertrophy through mitochondrial E3 ubiquitin ligase MUL1 Vasquez-Trincado, Cesar; Navarro, Mario; Morales, Pablo.; Westermeier, Franciaco; Chiong M.; Parra, Valentina; Espinosa, Alejandra; Lavandero S. Article FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2023)
Organelle Communication: Joined in Sickness and in Health Bravo-Sagua, Roberto; López, Camila; Criollo, Alfredo; Inagi, Reiko; Lavandero S. Article PHYSIOLOGY (2023)
Targeting VCAM-1: a therapeutic opportunity for vascular damage Troncoso, Mayarling Francisca; Diaz, Magda C.; Sanhueza-Olivares, Fernanda; Riquelme, Jaime; Muller, Marioly; Garrido, Luis; Gabrielli, Luigi; Chiong M.; Corbalan, Ramon Luis; Castro Pablo F.,; Lavandero S. Article EXPERT OPINION ON THERAPEUTIC TARGETS (2023)
The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage Rivera, Pablo; Narbona, Alvaro; Hasberg, Lidwina; Kroczek, Lara; Bahat, Amir; Lawo, Steffen; Folz, Kat; Schumacher, Anna; Ahola, Sofia; Mayer, Fiona; Giavalisco, Patrick; Nolte, Hendrik; Lamger, Thomas; Lavandero S. Article CELL REPORTS (2023)
Activation of Phosphodiesterase 3A: New Hope for Cardioprotection Chiong M.; Houslay, Miles; Lavandero S. Article CIRCULATION (2022)
Angiotensin-(1-9) in hypertension Norambuena, Ignacio; López, Camila; Martínez, Javiera; Hernández, Carolina; Parra, Valentina; Chiong, Mario; Lavandero S. Article BIOCHEMICAL PHARMACOLOGY (2022)
Autophagy in aging-related oral diseases Peña, Daniel; San Martin C.; Hernandez, M.; Morselli, Eugenia; Budini, Mauricio; Burgos Patricia; Criollo, Alfredo; Lavandero S. Article FRONTIERS IN ENDOCRINOLOGY (2022)
IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes Sánchez, Pablo; López, Camila; Norambuena, Ignacio; Pennanen, Christian; Zhu, Jumo; Bomer N; Hoes, Matijn; Meer Van Der, Peter; Westenbrink, B. Daan; Lavandero S. Article FRONTIERS IN PHYSIOLOGY (2022)
Impaired AMP-Activated Protein Kinase Signaling in Heart Failure With Preserved Ejection Fraction-Associated Atrial Fibrillation Tong, Dan; Schiattarella, Gabriele G.; Jiang, Nan; Daou, Daniel; Luo, Yuxuan; Link S Mark; Gillette, Thomas G.; Hill, Joseph A.; Lavandero S. Article CIRCULATION (2022)
Insulin signaling in the heart is impaired by growth hormone: a direct and early event Munoz, Marina; Piazza, Veronica; Burghi V.; Giani, Jorge; Martínez, Carolina.; Cicconi, Nadia; Muia, Nadia; Fang, Yimin; Sotelo, Ana; Bartke, Andrzej; Pennisi, Patricia; Dominici, Fernando; Miquet, Johanna; Lavandero S. Article JOURNAL OF MOLECULAR ENDOCRINOLOGY (2022)
Mitochondrial E3 ubiquitin ligase 1 (MUL1) as a novel therapeutic target for diseases associated with mitochondrial dysfunction Calle, Ximena; Garrido, Valeria; López, Erick; Norambuena, Ignacio; Martinez, Daniela; Penaloza-Otarola, Allan; Troncossi, Angelo; Guerrero-Moncayo, Alejandra; Ortega, Angelica; Maracaja-Coutinho, Vinicius; Parra, Valentina; Chiong, Mario; Lavandero S. Article IUBMB LIFE (2022)
Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment Ajoolabady A; Chiong M.; Klionsky, Daniel J; Ren, Jun; Lavandero S. Article TRENDS IN MOLECULAR MEDICINE (2022)
Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells Mondaca, David; Quiroga, Clara; Norambuena, Ignacio; Riquelme, Jaime; SAN MARTÍN, ALEJANDRA; Bustamante, Mario; Chiong M.; Lavandero S. Article JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2022)
The integrated stress response in ischemic diseases Zhang Guangyu; Wang Xiaoding; Rothermel, Beverly; Wang, Zhao V.; Lavandero S. Article CELL DEATH AND DIFFERENTIATION (2022)
The role of autophagy in cardiovascular pathology Gatica, Damián; Chiong, Mario Martin; Klionsky, Daniel J.; Lavandero S. Article CARDIOVASCULAR RESEARCH (2022)
Circulating Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Associated With Left Atrial Remodeling in Long-Distance Runners Contreras, Felipe; Herrera, Sebastian; Vega, Julián; Salinas, Manuel; Ocaranza, Maria Paz; Jalil, Jorge E.; Mandiola, Jorge; Garcia, Lorena; Chiong, Mario; Castro, Pablo F.; Gabrielli, Luigi; Lavandero S. Article FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy Luo, Yuxuan; Jiang, N; May, Herman I.; Luo, Xiang; Ferdous, Anwarul; Schiattarella, Gabriele G.; Chen, Guihao; Qinfeng Li; Chao Li; Rothermel, Berverly A; Jiang, Dingsheng; Gillette, Thomas G.; Hill, Joseph A; Lavandero S. Article CIRCULATION (2021)
Corrigendum to "Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol" [Experimental and Molecular Pathology Volume 92, Issue 1, February 2012, Pages 97-104] Ayala, Pedro; Montenegro, Jose; Vivar, Raúl; Letelier, Alan; Aránguiz, Pablo; Copaja Miguel; PIVET, DEISY; Humeres, Claudio; Troncoso, Rodrigo; Vicencio, José Miguel; DIAZ, Guillermo; Lavandero S. Article EXPERIMENTAL AND MOLECULAR PATHOLOGY (2021)
Endoplasmic reticulum-mitochondria coupling increases during doxycycline-induced mitochondrial stress in HeLa cells López, Camila; Díaz, Alexis; Castro Pablo F.,; Rothermel, Beverly; Bravo Sagua, Roberto; Lavandero S. Article CELL DEATH AND DISEASE (2021)
Left Cardiac Remodelling Assessed by Echocardiography Is Associated with Rho-Kinase Activation in Long-Distance Runners Contreras, Felipe; Vega, Julian; Mandiola, Jorge; Ocaranza, Maria Paz; Herrera, Sebastián; Salinas, Manuel; Fernandez, Rodrigo; Jalil, Jorge; Chiong, Mario; Godoy, Paz; Castro Pablo F.,; Sitges, Marta; Gabrielli, Luigi; Lavandero S. Article Journal of cardiovascular development and disease. (2021)
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction Tong, Dan; Schiattarella, Gabriele G.; Jiang, Nan; Altamirano, Francisco; Szweda, Pamela A.; Einwasany, Abdallah; Lee, I Dong; Yoo, Heesoo; Kass, David A; Szweda, Luke, I; Verdin, Eric; Gillette, Thomas G.; Hill, Joseph A; Lavandero S. Article CIRCULATION RESEARCH (2021)
Novel Insights Into the Pathogenesis of Diabetic Cardiomyopathy and Pharmacological Strategies Muñoz-Córdova, Felipe; Hernández, Carolina; López, Camila; Troncoso, Mayarling Francisca; Calle, Ximena; Guerrero-Moncayo, Alejandra; Gabrielli, Luigi; Chiong, Mario; Castro Pablo F.,; Lavandero S. Article FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
Novel molecular insights and public omics data in pulmonary hypertension López, Camila; Arias-Carrasco Raúl; Sepulveda, Pablo; Garrido, Luis; Maracaja-Coutinho, Vinicius; Verdejo, Hugo; Castro, Pablo; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)
Perspectives on Organelle Interaction, Protein Dysregulation, and Cancer Disease Díaz, Paula; Sandoval, Alejandra; Bravo Sagua, Roberto; Quest, Andrew F G; Lavandero, S Article FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1 Pena, Daniel; Rodríguez, Marcelo; Burgos, Francesca; Vergara, Angelo; Kretschmar C.; Sotomayor F, Cristián; Ramirez, Cesar; de Smedt, Humbert; Reyes, Montserrat; Perez, William; Torres, Vicente; Morselli E.; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Criollo, Alfredo; Lavandero S. Article AUTOPHAGY (2021)
Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy Fernandez, Carolina; Torrealba, Natalia; Altamirano, Francisco; Garrido, Valeria; Vasquez-Trincado, Cesar; Flores, Raúl; López, Camila; Ocaranza, Maria Paz; Chiong, Mario; Pedrozo, Zully; Lavandero S. Article PLOS ONE (2021)
Polycystin-1 regulates cardiomyocyte mitophagy Ramirez, Andrea; Quiroga, Clara; Garrido, Valeria; López, Camila; Leiva, Sebastian; Norambuena, Ignacio; Ortiz-Quintero, Jafet; Diaz, Magda C; Perez, William; Hendrickson, Troy; Parra, Valentina; Pedrozo, Zully; Altamirano, Francisco; Chiong M.; Lavandero S. Article FASEB JOURNAL (2021)
Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension Olivares, Francisco; De Gregorio, Nicole; Espitia-Corredor, Jenaro A.; Espinoza, Claudio; Vivar, Raúl; Silva, David; Osorio, Jose Miguel; Peiró, Concepción; Sanchez, Carlos; Diaz, Guillermo A.; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)
Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation Morales, Pablo E.; Matías Monsalves-Alvarez; Tadinada, Satya Murthy; Harris, Matthew P.; Ramirez, Andrea; Ortiz-Quintero, Jafet; Troncoso, Mayarling Francisca; De Gregorio, Nicole; Calle, Ximena; Pereira, Renata C.; Lira, Vitor A.; Espinosa, Alejandra; Abel, E. Dale; Lavandero S. Article FASEB JOURNAL (2021)
Targeting the Endothelium to Achieve Cardioprotection Herrera, Nicolas; Zuniga-Cuevas, Ursula; Ramirez, Andres; Riquelme, Jaime; Lavandero S. Article FRONTIERS IN PHARMACOLOGY (2021)
Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy Francisca Troncoso, Mayarling; Pavez, Mario; Perez-Wilson, Carlos; Lagos, Daniel; Duran, Javier; Ramos, Sebastian; Barrientos, Genaro; Silva, Patricio; Llanos, Paola; Basualto, Carla; B. Daan Westenbrink; Estrada, Manuel I.; Lavandero S. Article BIOLOGICAL RESEARCH (2021)
Vaccines against components of the renin-angiotensin system GARAY, NOÉ; Hernández, Carolina; Garcia-Rivas, Gerardo; Guerrero, Carlos; Lavandero S. Article HEART FAILURE REVIEWS (2021)
Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction Schiattarella, Gabriele G.; Altamirano, Francisco; Kim, Soo Young; Tong, Dan; Ferdous, Anwarul; Piristine, Hande; Dasgupta, S.; Wang, X; French, Kristin M.; Villalobos, Elisa; Spurgin, Staphen B; Waldman, Maayan; Jiang, Nan; May, Herman; Hill, Theodore; Luo, Yuxuan; Yoo, Heesoo; Zaha, Vlad; Gillette, Thomas G.; Hill, Joseph A; Lavandero S. Article NATURE COMMUNICATIONS (2021)
Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway Sotomayor F, Cristián; Rivera, Pablo; Vasquez-Trincado, Cesar; López, Camila; Morales, Pablo.; Pennanen C.; Polakovicova, Iva; Aliaga-Tobar, Victor; Garcia, Lorena; Roa, Juan Carlos; Rothermel, Beverly; Maracaja-Coutinho, Vinicius; Ho-Xuan H.; Meister G.; Chiong M.; Ocaranza, Maria Paz; Corvalan, Alejandro; Parra, Valentina; Lavandero S. Article CELL DEATH AND DIFFERENTIATION (2020)
Angiotensin-(1-9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism Norambuena, Ignacio; Ocaranza, Maria Paz; Cancino-Arenas, Nicole; Sanhueza-Olivares, Fernanda; Villar, Paulina; Leiva, Sebastian; Mancilla, Cristian; Moya, Jacqueline; Novoa, Ulises; Jalil, Jorge E.; Castro Pablo F.,; Chiong M.; Lavandero S. Article BIOCHEMICAL PHARMACOLOGY (2020)
Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway Sotomayor-Flores C.; Rivera-MejÃas P.; VÃ¡squez-Trincado C.; LÃ³pez-Crisosto C.; Morales P.E.; Pennanen C.; Polakovicova I.; Aliaga-Tobar V.; GarcÃa L.; Roa, J.C; Rothermel, B. A.; Maracaja-Coutinho V.; Ho-Xuan H.; Meister G.; Chiong M.; Ocaranza M.P.; CorvalÃ¡n A.H.; Parra V.; Lavandero S. Article ISI SCOPUS Cell Death and Differentiation (2020)
Autophagy Activation in Zebrafish Heart Regeneration Chávez, Myra N.; Morales, Rodrigo A.; López-Crisosto, Camila; Roa, Juan Carlos; Allende, Miguel L.; Lavandero, Sergio Article SCOPUS SCIENTIFIC REPORTS (2020)
beta-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle Monsalves-Alvarez, Matias; Morales, Pablo Esteban; Castro-Sepulveda, Mauricio; Sepulveda, Carlos; Rodriguez, Juan Manuel; Chiong, Mario; Eisner, Veronica; Lavandero, Sergio; Troncoso, Rodrigo Article ISI NUTRIENTS (2020)
Calcium-Sensing Receptor in Adipose Tissue: Possible Association with Obesity-Related Elevated Autophagy Mattar, Pamela; Sanhueza, Sofia; Yuri, Gabriela; Briones, Lautaro; Perez, Claudio; Rudich, Assaf; Cifuentes, Mariana; Lavandero S. Article INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Cohort Profile: The Maule Cohort (MAUCO) Ferreccio, Catterina; Huidobro, Andrea; Cortés, Sandra; Bambs, Claudia; Toro, Pablo; Van De Wyngard, Vanessa; Acevedo, Johanna; Paredes, Fabio; Venegas, Pía; Verdejo, Hugo; Oyarzún-González, Ximena; Cook, Paz; Castro, Pablo F; Foerster, Claudia; Vargas, Claudio; Koshiol, Jill; Araya, Juan Carlos; Cruz, Francisco; Corvalán, Alejandro H; Quest, Andrew F; Kogan, Marcelo J; Lavandero, Sergio Article International Journal of Epidemiology (2020)
Early left atrial dysfunction is associated with suboptimal cardiovascular health Ocaranza M.P.; Bambs C.; Salinas M.; Matamala, C; Garcia L.; Troncoso R.; Pedrozo Z.; Huidobro A.; Venegas P.; Paredes F.; Giacaman A.; Zalaquett R.; Chiong M.; Verdejo H.E.; Ferreccio C.; Lavandero S.; Castro P.F.; Gabrielli L. Article ISI SCOPUS ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2020)
Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function Kim, Soo Young; Zhang X.; Schiattarella, Gabriele; Altamirano, Francisco; Ramos, Thais A. R.; French, Kristin M.; Jiang, Nan; Szweda, Pamela A.; Evers, Bret M.; May, Herman I.; Luo, Xiang; Li, Hongliang; Szweda, Luke, I; Maracaja-Coutinho, Vinicius; Gillette, Thomas G.; Hill, Joseph A; Lavandero S. Article CIRCULATION (2020)
FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth Ferdous, Anwarul; Wang, Zhao, V; Luo, Yuxuan; Li, Dan L.; Luo, Xiang; Schiattarella, Gabriele G.; Altamirano, Francisco; May, Herman, I; Battiprolu, Pavan K.; Nguyen, Annie; Rothermel, Beverly A.; Lavandero, Sergio; Gillette, Thomas G.; Hill, Joseph A Article ISI NATURE COMMUNICATIONS (2020)
Increased production of functional small extracellular vesicles in senescent endothelial cells Riquelme, J. A.; Takov K.; Santiago-FernÃ¡ndez C.; Rossello X.; Lavandero S.; Yellon D.M.; Davidson S.M. Article ISI SCOPUS JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia Sanchez, Gina; Chalmers, Stefanie; Ahumada, Xavier; Montecinos, Luis; Olmedo, Ivonne; Eisner, Veronica; Riveros, Ana; Kogan, Marcelo J.; Lavandero, Sergio; Pedrozo, Zully; Donoso, Paulina Article ISI PLOS ONE (2020)
Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury Olmedo I.; Pino G.; Riquelme, J. A.; Aranguiz P.; DÃaz M.C.; LÃ³pez-Crisosto C.; Lavandero S.; Donoso P.; Pedrozo Z.; SÃ¡nchez G. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2020)
Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases? Diaz-Vegas, Alexis; Sanchez-Aguilera, Pablo; Krycer, James R.; Morales, Pablo E.; Monsalves-Alvarez, Matias; Cifuentes, Mariana; Rothermel, Beverly A.; Lavandero, Sergio Article ISI ENDOCRINE REVIEWS (2020)
Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with gold nanoclusters Bejarano, Julian; Rojas, Aldo; Ramirez, Andrea; Riveros, Ana L.; Morales-Zavala, Francisco; Flores, Yvo; riquelme, jaime alejandro; Guzman, Fanny; Araya, Eyleen; Chiong, Mario; Ocaranza, Maria Paz; Morales, Javier; Villamizar-Sarmiento, María Gabriela; Sanchez, Gina; KOGAN, MARCELO; Lavandero S. Article JOURNAL OF CONTROLLED RELEASE (2020)
Manipulation of ACE2 expression in COVID-19 Chaudhry, Farhan; Xiang, X; Sabharwal, Basera; Zheng, Ying-Ying; Correa, Ashish; Narula J.; Levy, Phillip; Lavandero S. Article OPEN HEART (2020)
New emerging roles of Polycystin-2 in the regulation of autophagy Pena, Daniel; Batista, Ana; Kretschmar C.; Burgos, Paulina; Lavandero S.; Morselli E.; Criollo, Alfredo Article INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY (2020)
Preoperative soluble VCAM-1 contributes to predict late mortality after coronary artery surgery Corbalan, Ramon; Garcia, Mauricio; Garrido-Olivares, L.; Garcia, Lorena; Perez, Gonzalo; MELLADO, ROSEMERIE; Zalaquett, Ricardo; Chiong M.; Quitral, Jorge; Lavandero S. Article CLINICAL CARDIOLOGY (2020)
Rho-kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with reduced ejection fraction Ocaranza M.P.; Moya J.; Jalil J.E.; Lavandero S.; Kalergis A.M.; Molina C.; Gabrielli L.; Godoy I.; CÃ³rdova S.; Castro P.; Mac Nab P.; Rossel V.; GarcÃa L.; GonzÃ¡lez J.; Mancilla C.; Fierro C.; FarÃas L. Article ISI SCOPUS JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Role of Autophagy in the Microenvironment of Oral Squamous Cell Carcinoma Peña, Daniel; Reyes, Montserrat; Hernandez-Caceres, Maria Paz; Kretschmar, Catalina; Morselli, Eugenia; Ramirez, Cesar A.; Torres, Vicente; Criollo, Alfredo; Lavandero S. Article FRONTIERS IN ONCOLOGY (2020)
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-?1 Vivar R.; Humeres, C.; Anfossi R.; Bolivar S.; CatalÃ¡n M.; Hill J.; Lavandero S.; Diaz-Araya G. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Cell Research (2020)
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1 Vivar, Raúl; Humeres, Claudio; Anfossi, Renatto; Bolívar Samir; Catalán, Mabel; Hill, Joseph A.; DIAZ, Guillermo; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)
β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle Monsalves, Matías; Morales, Pablo.; Castro, MAuricio; Sepulveda, Carlos; Rodriguez, Juan Manuel; Chiong M.; Eisner, Veronica; Troncoso, Rodrigo; Lavandero S. Article NUTRIENTS (2020)
Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy Mondaca-Ruff, D; Riquelme, JA; Quiroga, C; Norambuena-Soto, I; Sanhueza-Olivares, F; Villar-Fincheira, P; Hernandez-Diaz, T; Cancino-Arenas, N; Martin, AS; Garcia, L; Lavandero, S; Chiong, M Article ISI SCOPUS FRONTIERS IN PHARMACOLOGY (2019)
AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells MartÃnez-Meza S.; DÃaz J.; Sandoval-BÃ³rquez A.; Valenzuela-Valderrama M.; DÃaz-Valdivia N.; Rojas-Celis V.; Contreras P.; Huilcaman R.; Ocaranza M.P.; Chiong M.; Leyton L.; Lavandero S.; Quest A.F.G. Article ISI SCOPUS CANCERS (2019)
Author Correction: Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress Bravo Sagua, Roberto; Parra, Valentina; Ortiz, Carolina; Navarro, Mario; Rodriguez, Andrea; Diaz, Natalia; Sanhueza, Carlos; Lopez, Camila; Tahbaz, Nasser; Rothermel, Beverly; Hill, Joseph A.; Cifuentes, Mariana; Simmen, Thomas; Quest, Andrew F; Lavandero S. Article CELL DEATH AND DIFFERENTIATION (2019)
Bafilomycin-A1 and ML9 Exert Different Lysosomal Actions to Induce Cell Death Shaikh, Soni; Nandy, SK; Canti, Carles; Lavandero S. Article CURRENT MOLECULAR PHARMACOLOGY (2019)
Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress Bravo-Sagua, R; Parra, V; Ortiz-Sandoval, C; Navarro-Marquez, M; Rodriguez, AE; Diaz-Valdivia, N; Sanhueza, C; Lopez-Crisosto, C; Tahbaz, N; Rothermel BA; Hill, JA; Cifuentes, M; Simmen, T; Quest, AFG; Lavandero, S Article ISI CELL DEATH AND DIFFERENTIATION (2019)
Counter-regulatory renin-angiotensin system in cardiovascular disease Ocaranza, Maria Paz; Riquelme, Jaime; Garcia, Lorena; Jalil, Jorge; Chiong M.; Santos, Robson A.; Lavandero S. Article NATURE REVIEWS CARDIOLOGY (2019)
Editorial commentary: Cardiometabolic diseases and gut microbiota-removing the veil Riquelme, Jaime; Ferreccio R, Catterina; Lavandero S. Article TRENDS IN CARDIOVASCULAR MEDICINE (2019)
Fibroblast Primary Cilia Are Required for Cardiac Fibrosis Villalobos, Elisa; Criollo, Alfredo; Schiattarella, Gabriele G.; Altamirano, Francisco; French, Kristin M.; May, Herman, I; Jiang, Nan; Ngoc Uyen Nhi Nguyen; Romero, Diego; Carlos Roa, Juan; Garcia, Lorena; Diaz-Araya, Guillermo; Morselli, Eugenia; Ferdous, Anwarul; Conway, Simon J.; Sadek, Hesham A.; Gillette, Thomas G.; Lavandero, Sergio; Hill, Joseph A Article ISI SCOPUS CIRCULATION (2019)
GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication Garrido-Moreno, Valeria; Díaz-Vegas, Alexis; López-Crisosto, Camila; Troncoso, Mayarling Francisca; Navarro-Marquez, Mario; García, Lorena; Estrada, Manuel; Cifuentes, Mariana; Lavandero, Sergio Article ISI SCOPUS PHARMACOLOGICAL RESEARCH (2019)
Looking back and thinking forwards - 15 years of cardiology and cardiovascular research Kalman, J.; Mahfoud, Felix; Nahrendorf M.; Yacoub, Magdi H.; Zhao D.; Lavandero S. Article NATURE REVIEWS CARDIOLOGY (2019)
Nitrosative stress drives heart failure with preserved ejection fraction Schiattarella, Gabriele G.; Altamirano, Francisco; Tong, Dan; French, Kristine; Villalobos, E; Kim, Soo Young; Luo, Xiang; Jiang, Nan; May, Herman I.; Wang, Zhao V.; Hill, Theodore; Mammen P.P.A.; huang jian; Lee, Dong; Hahn V.S.; Sharma K.; Kass, David A; Gillette, Thomas G.; Hill, Joseph A; Lavandero S. Article NATURE (2019)
Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility Altamirano F.; Schiattarella G.G.; French K.M.; Kim S.Y.; Engelberger F.; Kyrychenko S.; Villalobos E.; Tong D.; Schneider J.W.; Ramirez-Sarmiento C.A.; Lavandero S.; Gillette, T. G.; Hill J.A. Article ISI SCOPUS CIRCULATION (2019)
TGF-beta 1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts Catalán, Mabel; Aránguiz, Pablo; Boza, Pía; Olmedo, Ivonne; Humeres, Claudio; Vivar, Raúl; Anfossi, Renatto; Ayala, Pedro; Espinoza, Claudio; Lavandero, Sergio; Díaz-Araya, Guillermo Article ISI SCOPUS MOLECULAR BIOLOGY REPORTS (2019)
TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts Catalán, Mabel; Aránguiz, Pablo; Boza, Pía; Olmedo, Ivonne; Humeres, Claudio; Vivar, Raúl; Anfossi, Renatto; Ayala, Pedro; Espinoza, Claudio; Diaz, Guillermo A.; Lavandero S. Article MOLECULAR BIOLOGY REPORTS (2019)
The Association of Ascorbic Acid, Deferoxamine and N-Acetylcysteine Improves Cardiac Fibroblast Viability and Cellular Function Associated with Tissue Repair Damaged by Simulated Ischemia/Reperfusion Parra-Flores P.; Riquelme, J. A.; Valenzuela-Bustamante P.; Leiva-Navarrete S.; Vivar R.; Cayupi-Vivanco J.; Castro E.; Espinoza-PÃ©rez C.; Ruz-CortÃ©s F.; Pedrozo Z.; Lavandero S.; Rodrigo R.; Diaz-Araya G. Article ISI SCOPUS ANTIOXIDANTS (2019)
TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals Jimenez, Jose M.; Salazar, Michelle L. ; Arancibia, Sergio; Villar, Javiera; Salazar, Fabian; Brown, Gordon D.; Lavelle, Ed C.; Martinez-Pomares, Luisa; Ortiz-Quintero, Jafet; Lavandero, Sergio; Manubens, Augusto; Ines Becker, Maria Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
[Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units] Hameau, René; Gabrielli, Luigi; Garrido, Marcelo; Guzmán, Ana María; Retamal, Ignacio; Vacarezza, María José; Greig, Douglas; Ocqueteau, Mauricio; Sanchez, Cesar; Pizarro, Marcela; Corvalan, Alejandro; Castro Pablo F.,; Martínez, Gonzalo; Lavandero S. Article REVISTA MEDICA DE CHILE (2018)
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension González, Leticia; Novoa, Ulises; Moya, Jackeline; Gabrielli, Luigi; Jalil, Jorge; Garcia, Lorena; Chiong M.; Ocaranza, Maria Paz; Lavandero S. Article BIOCHEMICAL PHARMACOLOGY (2018)
Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state? Peña, Daniel; Bravo, Roberto; Díaz-Vegas Alexis; Aleman, Larissa; Chiong M.; Garcia, Lorena; Bambs, Claudia; Troncoso R.; Cifuentes, Mariana; Morselli, Eugenia; Ferreccio R, Catterina; Quest, Andrew; Criollo, Alfredo; Lavandero S. Article FREE RADICAL BIOLOGY AND MEDICINE (2018)
Autophagy mediates calcium-sensing receptor-induced TNFα production in human preadipocytes Mattar, Pamela; Bravo, Roberto; Tobar, Nicolás; Fuentes, Cecilia; Troncoso, Rodrigo; Breitwieser, Gerda; Cifuentes, Mariana; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro Davidson, SM; Riquelme, JA; Takov, K; Vicencio, JM; Boi-Doku, C; Khoo, V; Doreth, C; Radenkovic, D; Lavandero, S; Yellon, DM Article ISI JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Down Syndrome Critical Region 1 Gene, , Helps Maintain a More Fused Mitochondrial Network. Parra, Valentina; Altamirano, Francisco; Hernández-Fuentes, Carolina P; Tong, Dan; Kyrychenko, Victoriia; Rotter, David; Pedrozo, Zully; Hill, Joseph A; Eisner, Verónica; Lavandero, Sergio; Schneider, Jay W; Rothermel, Beverly A Article Circulation research (2018)
Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning Davidson, Sean M.; Riquelme, Jaime; Ying, Zheng; Vicencio, Jose; Yellon D.M.; Lavandero S. Article SCIENTIFIC REPORTS (2018)
Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis Navarro-Marquez, M; Torrealba, Natalia; Troncoso, Rodrigo; Vasquez-Trincado, Cesar; Rodríguez, Marcelo; Morales, Pablo.; Villalobos, Elisa; Eura, Y; Garcia, Lorena; Chiong M.; Klip, A; Jaimovich E.; Kokame, K; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Increased active phase atrial contraction is related to marathon runner performance Gabrielli, Luigi; Herrera, Sebastian; Contreras, Felipe; Vega, Julian; Ocaranza, Maria Paz; Yáñez, Fernando; Saavedra, Rodrigo; Stiges, Marta; Garcia, Lorena; Chiong, Mario; Castro Pablo F.,; Lavandero S. Article EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2018)
IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice Valladares, Denisse; Utreras, Yildy; Campos, Cristian; Morales, Camilo; Díaz-Vegas Alexis; Contreras, Ariel; Westermeier, Francisco; Jaimovich, Enrique; Marchi S.; Pinton, Paolo; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism Cordova-Casanova, A; Olmedo I.; Riquelme, J. A.; Barrientos, G; Sánchez G; Gillette, T. G.; Lavandero S.; Chiong M.; Donoso P.; Pedrozo Z.; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2018)
Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches Bejarano, Julian; Navarro, Mario; Morales, Francisco; Morales, Javier; Garcia, Ivonne; Araya, Eyleen; Flores, Yvo; Verdejo Hugo E.; Castro Pablo F.,; Lavandero S.; Kogan Marcelo J. Article THERANOSTICS (2018)
Polycystin-2-dependent control of cardiomyocyte autophagy Criollo, Alfredo; Altamirano, F; Pedrozo, Zully; Schiattarella, Gabriele G.; Li, Dan; Rivera, Pablo; Sotomayor F, Cristián; Parra, Valentina; Villalobos, Elisa; Battiprolu, Pavan; Jiang, Nan; May, Herman, I; Morselli, Eugenia; Somlo, Stefan; de Smedt, Humbert; Gillette, Thomas G.; Hill, Joseph A.; Lavandero S. Article JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2018)
Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance Gabrielli, Luigi; Stiges, Marta; Chiong M.; Jalil, Jorge; Ocaranza, Maria Paz; Llevaneras M., Silvana; Herrera, Sebastián; Fernandez, Rodrigo; Saavedra, Rodrigo; Yáñez, Fernando; Vergara, Luis; Díaz, Alexis; Lavandero, Sergio; Castro Pablo F., Article EUROPEAN JOURNAL OF SPORT SCIENCE (2018)
Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT2R and Akt-dependent mechanism Mendoza-Torres, Evelyn; Riquelme, Jaime; Vielma, Alejandra Z.; Ramirez, Andrea; Gabrielli, Luigi; Bravo, Roberto; Jalil, Jorge; Rothermel, Beverly; Sanchez, Gina; Ocaranza, Maria Paz; Lavandero S. Article PHARMACOLOGICAL RESEARCH (2018)
The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content Shaikh, S.; Troncoso R.; Mondaca-Ruff, David; Parra, Valentina; Garcia, L.; Chiong M.; Lavandero S. Article Toxicology in vitro : an international journal published in association with BIBRA. (2018)
Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension. Gabrielli, Luigi; Ocaranza, María Paz; Sitges, Marta; Kanacri, Andrés; Saavedra, Rodrigo; Sepulveda, Pablo; Sepulveda, Luis; Rossel, Victor; Zagolin, Monica; Verdejo, Hugo E; Baraona, Fernando; Zalaquett, Ricardo; Chiong, Mario; Lavandero, Sergio; Castro, Pablo F Article Echocardiography (Mount Kisco, N.Y.) (2017)
Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension. Gabrielli, Luigi; Ocaranza, María Paz; Sitges, Marta; Kanacri, Andrés; Saavedra, Rodrigo; Sepulveda, Pablo; Sepulveda, Luis; Rossel, Victor; Zagolin, Monica; Verdejo, Hugo E; Baraona, Fernando; Zalaquett, Ricardo; Chiong, Mario; Lavandero, Sergio; Castro, Pablo F Article Echocardiography (Mount Kisco, N.Y.) (2017)
Calcium Transport and Signaling in Mitochondria. Bravo-Sagua, Roberto; Parra, Valentina; López-Crisosto, Camila; Díaz, Paula; Quest, Andrew F G; Lavandero, Sergio Article Comprehensive Physiology (2017)
Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation Torrealba, N; Navarro-Marquez, M; Garrido, V; Pedrozo, Z; Romero, D; Eura, Y; Villalobos, E; Roa, JC; Chiong, M; Kokame, K; Lavandero, S Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation. Del Campo, Andrea; Roldán, Juan; Verdejo, Hugo E; Zalaquett, Ricardo; Becerra, Elia; Navarro-Marquez, Mario; Mellado, Rosemarie; Lavandero, Sergio; Corbalán, Ramón; García, Lorena; Chiong, Mario Article Journal of cardiology (2017)
Mitochondria in Structural and Functional Cardiac Remodeling. Torrealba, Natalia; Aranguiz, Pablo; Alonso, Camila; Rothermel, Beverly A; Lavandero, Sergio Article Advances in experimental medicine and biology (2017)
Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology Lopez-Crisosto, Camila; Pennanen, Christian; Vasquez-Trincado, Cesar; Morales, Pablo E; Bravo-Sagua, Roberto; Quest, Andrew F G; Chiong, Mario; Lavandero, Sergio Article Nature Reviews Cardiology (2017)
Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology Lopez-Crisosto, Camila; Pennanen, Christian; Vasquez-Trincado, Cesar; Morales, Pablo E; Bravo-Sagua, Roberto; Quest, Andrew FG; Chiong, Mario; Lavandero, Sergio Article Nature Reviews Cardiology (2017)
Subcellular Remodeling of the T-Tubule Membrane System=> The Limits of Myocardial Recovery Revealed? Rame, J Eduardo; Lavandero, Sergio Article Circulation (2017)
Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial Fibrillation in Elderly Patients Verdejo, HE; Becerra E.; Zalaquet, R; del Campo, A; Garcia, L.; Troncoso R.; Chiong M.; MarÍn A.; Castro, PF; Lavandero S.; Gabrielli, L; Corbalan, R Article ISI SCOPUS ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES (2016)
BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism Rodríguez A.E.; Lopez-Crisosto C.; Peña-Oyarzún D.; Salas, D.; Parra, V; Quiroga, C; Morawe T.; Chiong M.; Behl C.; Lavandero S. Article ISI SCOPUS AUTOPHAGY (2016)
Calcium Sensing Receptor as a Novel Mediator of Adipose Tissue Dysfunction: Mechanisms and potential Clinical Implications Bravo-Sagua, R; Mattar, P; Diaz, X; Lavandero, S; Cifuentes, M Article ISI FRONTIERS IN PHYSIOLOGY (2016)
Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism Riquelme, JA; Westermeier, F; Hall, AR; Vicencio, JM; pedrozo, Z; Ibacache M.; Fuenzalida, B; Sobrevia L.; Davidson, SM; Yellon, DM; Sánchez G; Lavandero S. Article ISI SCOPUS PHARMACOLOGICAL RESEARCH (2016)
FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation Vivar, R; Humeres, C.; Munoz, C; Boza P.; Bolivar S.; Tapia, F; Lavandero S.; Chiong M.; Diaz-Araya, G Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor Paredes, F; Parra, V; Torrealba, N; Navarro-Marquez, M; Gatica, D; Bravo Sagua R; Troncoso R.; Pennanen C.; Quiroga, C; Chiong M.; Caesar, C.; Taylor, WR; Molgó J.; Martin, AS; Jaimovich E.; Lavandero S. Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2016)
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells. Rosas, Carlos; Oróstica, Lorena; Poblete, Cristian; Carvajal, Rodrigo; Gabler, Fernando; Romero, Carmen; Lavandero, Sergio; Vega, Margarita Article Reproductive sciences (Thousand Oaks, Calif.) (2016)
Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression Morales C.R.; Li D.L.; pedrozo, Z; May H.I.; Jiang, N; Kyrychenko V.; Cho G.W.; Kim, S. Y.; Wang Z.V.; Rotter D.; Rothermel, B. A.; Schneider J.W.; Lavandero S.; Gillette, T. G.; Hill J.A. Article ISI SCOPUS SCIENCE SIGNALING (2016)
Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival Campos, T.; Ziehe J.; Fuentes-Villalobos, F.; Riquelme O.; Peña D.; Troncoso R.; Lavandero S.; Morin, V; Pincheira, R; Castro A F. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Regulation of cardiomyocyte autophagy by calcium. Shaikh, Soni; Troncoso, Rodrigo; Criollo, Alfredo; Bravo-Sagua, Roberto; García, Lorena; Morselli, Eugenia; Cifuentes, Mariana; Quest, Andrew F G; Hill, Joseph A; Lavandero, Sergio Article American journal of physiology. Endocrinology and metabolism (2016)
Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024 Ferreccio C.; Roa, JC; Bambs C.; Vives, A; Corvalan, AH; Cortés S.; Foerster, C; Acevedo, J; Huidobro A.; Passi, A; Toro, P; Covacevich, Y; de la Cruz R.; Koshiol, J; Olivares M.; Miquel, JF; Cruz F.; Silva R.; Quest, AF; Kogan, MJ; Castro, PF; Lavandero S. Article ISI SCOPUS BMC PUBLIC HEALTH (2016)
Therapeutic targeting of autophagy in myocardial infarction and heart failure. Riquelme, Jaime A; Chavez, Myra N; Mondaca-Ruff, David; Bustamante, Mario; Vicencio, Jose Miguel; Quest, Andrew F G; Lavandero, Sergio Article Expert review of cardiovascular therapy (2016)
TonEBP suppresses IL-10-mediated immunomodulation Choi S.Y.; Lee H.H.; Lee, J. H.; Ye B.J.; Yoo E.J.; Kang H.J.; Jung G.W.; An S.M.; Lee-Kwon W.; Chiong M.; Lavandero S.; Kwon H.M. Article ISI SCOPUS SCIENTIFIC REPORTS (2016)
FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes Oyarzún, AP; Westermeier, F; Pennanen C.; López-Crisosto, C; Parra, V; Sotomayor-Flores, C; Sánchez G; pedrozo, Z; Troncoso R.; Lavandero S. Article ISI SCOPUS Biochemical Pharmacology (2015)
Glutathione Depletion Induces Spermatogonial Cell Autophagy Mancilla, H.; Maldonado R.; Cereceda, K.; Villarroel-Espindola, F; Montes de Oca M.; Angulo, C; Castro MA; Slebe, JC; Vera, JC; Lavandero S.; Concha, II Article ISI SCOPUS Journal of Cellular Biochemistry (2015)
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells Rosas, C; Oróstica L.; Poblete C.; Carvajal R.; Gabler F.; Romero C.; Lavandero S.; Vega M. Article SCOPUS Reproductive Sciences (2015)
Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases Morales, JO; Sepulveda-Rivas, S; Oyarzun Ampuero, F; Lavandero S.; Kogan, MJ Article ISI CURRENT PHARMACEUTICAL DESIGN (2015)
Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability pedrozo, Z; Criollo, A; Battiprolu, PK; Morales, CR; Contreras-Ferrat, A; Fernandez, C.; Jiang, N; Luo X.; Caplan, MJ; Somlo, S; Rothermel BA; Gillette, TG; Lavandero S.; Hill, JA Article ISI SCOPUS Circulation (2015)
Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition Salas, D.; Puebla, C; Lampe, PD; Lavandero S.; Sáez JC Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2015)
Unsaturated fatty acids induce non-canonical autophagy Niso-Santano, M; Malik, SA; Pietrocola, F; Bravo-San Pedro, JM; Marino, G; Cianfanelli, V; Ben-Younes, A; Troncoso R.; Markaki, M; Sica, V; Izzo V.; Chaba, K; Bauvy, C; Dupont N.; Kepp, O; Rockenfeller, P; Wolinski, H; Madeo, F; Lavandero S.; Codogno, P; Harper, F; Pierron, G; Tavernarakis, N; Cecconi, F; Maiuri, MC; Galluzzi L.; Kroemer G. Article ISI SCOPUS EMBO Journal (2015)
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system. Ocaranza MP, Michea L, Chiong M, Lavandero S, Jalil JE. Article Clin Sci (2014)
4-Phenylbutyric acid prevent cytotoxicity induced by thapsigargin in rat cardiac fibroblast Humeres, C.; Montenegro, J.; Varela, M.; Ayala, P; Vivar, R; Letelier, A; Olmedo, I; Catalán M.; Rivas, C; Baeza, P; Munoz, C; Garcia, L.; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS Toxicology in vitro : an international journal published in association with BIBRA. (2014)
A novel dihydropyridine with 3-aryl meta-hydroxyl substitution blocks L-type calcium channels in rat cardiomyocytes Galvis-Pareja, D; Zapata-Torres, G; Hidalgo J.; Ayala, P; pedrozo, Z; Ibarra, C; Diaz-Araya, G; Hall, AR; Vicencio, JM; Nunez-Vergara, L; Lavandero S. Article ISI SCOPUS TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes Gutiérrez T.; Parra, V; Troncoso R.; Pennanen C.; Contreras-Ferrat, A; Vasquez-Trincado, C; Morales PE; López-Crisosto, C; Sotomayor-Flores, C; Chiong M.; Rothermel BA; Lavandero S. Article ISI SCOPUS CELL COMMUNICATION AND SIGNALING (2014)
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis Ocaranza, Maria Paz; Moya, Jackeline; Barrientos, Victor; Alzamora, Rodrigo; Hevia, Daniel; Morales, Cristobal; Pinto, Melissa; Escudero, Nicolas; Garcia, Lorena; Novoa, Ulises; Ayala, Pedro; Diaz-Araya, Guillermo; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge E.; Michea, Luis Article ISI SCOPUS JOURNAL OF HYPERTENSION (2014)
Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells Li, Q.; Zhu, X; Ishikura, S; Zhang, D; Gao, J; Sun, Y; Contreras-Ferrat, A; Foley, KP; Lavandero S.; Yao, Z; Bilan, PJ; Klip, A; Niu, W Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance Troncoso R.; Paredes, F; Parra, V; Gatica, D; Vasquez-Trincado, C; Quiroga, C; Bravo Sagua R; López-Crisosto, C; Rodríguez, AE; Oyarzún, AP; Kroemer G.; Lavandero S. Article ISI SCOPUS CELL CYCLE (2014)
Effects of Trimetazidine in Nonischemic Heart Failure: A Randomized Study Winter, JL; Castro, PF; Quintana, JC; Altandrano, R; Enriquez A.; Verdejo, HE; JALIL, JE; Mellado R.; Concepcion, R; Sepúlveda P.; Rossel V.; Sepulveda, L; Chiong M.; Garcia, L.; Lavandero S. Article ISI SCOPUS JOURNAL OF CARDIAC FAILURE (2014)
Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy Xie M.; Kong, YL; Tan W.; May, H; Battiprolu, PK; pedrozo, Z; Wang, ZV; Morales C. ; Luo X.; Cho G.; Jiang, N; Jessen, ME; Warner, JJ; Lavandero S.; Gillette, TG; Turer, AT; Hill, JA Article ISI SCOPUS CIRCULATION (2014)
Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation Contreras-Ferrat, A; Llanos P.; Vásquez C.; Espinosa, A.; Osorio-Fuentealba, C; Arias-Calderon, M; Lavandero S.; Klip, A; Hidalgo C.; Jaimovich E. Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2014)
Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF kappa B-Opa-1 Signaling Pathway Parra, V; Verdejo, HE; Iglewski, M; del Campo, A; Troncoso R.; Jones D.; Zhu, Y; Kuzmicic J.; Pennanen C.; López-Crisosto, C; Jaña F; Ferreira J.; Noguera, E; Chiong M.; Bernlohr, DA; Klip, A; Hill, JA; Rothermel BA; Abel, ED; Zorzano, A; Lavandero S. Article ISI SCOPUS DIABETES (2014)
Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway Pennanen, Christian; Parra, Valentina; López-Crisosto, Camila; Morales, Pablo E; del Campo, Andrea; Gutierrez, Tomás; Rivera-Mejías, Pablo; Kuzmicic, Jovan; Chiong, Mario; Zorzano, Antonio; Rothermel, Beverly A; Lavandero, Sergio Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2014)
Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake del Campo, A; Parra, V; Vasquez-Trincado, C; Gutiérrez T.; Morales PE; López-Crisosto, C; Bravo Sagua R; Navarro-Marquez, MF; Verdejo, HE; Contreras-Ferrat, A; Troncoso R.; Chiong M.; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Organelle communication: Signaling crossroads between homeostasis and disease Bravo-Sagua, R; Torrealba, N; Paredes, F; Morales, PE; Pennanen, C; López-Crisosto, C; Troncoso, R; Criollo, A; Chiong, M; Hill, JA; Simmen, T; Quest, AF; Lavandero, S Article ISI SCOPUS INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics Hahn, WS; Kuzmicic J.; Burrill, JS; Donoghue, MA; Foncea, R; Jensen, MD; Lavandero S.; Arriaga, EA; Bernlohr, DA Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Role of Heterotrimeric G Protein and Calcium in Cardiomyocyte Hypertrophy Induced by IGF-1 CARRASCO L.; Cea, P; Rocco, P; Pena-Oyarzun, D; Rivera-Mejias, P; Sotomayor-Flores, C; Quiroga, C; Criollo, A; Ibarra, C; Chiong M.; Lavandero S. Article ISI SCOPUS JOURNAL OF CELLULAR BIOCHEMISTRY (2014)
Serotonin (5-HT) Regulates Neurite Outgrowth Through 5-HT1A and 5-HT7 Receptors in Cultured Hippocampal Neurons Rojas, PS; Neira D.; Munoz M.; Lavandero S.; Fiedler, JL Article ISI SCOPUS JOURNAL OF NEUROSCIENCE RESEARCH (2014)
Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway Wang, ZV; Deng Y., Gao N; Pedrozo Z., Li; DL, Morales; CR, Criollo A; Luo, X; Tan, W; Jiang N., Lehrman; MA, Rothermel; BA, Lee; AH, Lavandero S.; Mammen PP, Ferdous A.; Gillette, TG; Scherer, PE; Hill, JA Article CELL (2014)
Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway. [8] Wang ZV, Deng Y, Gao N, Pedrozo Z, Li DL, Morales CR, Criollo A, Luo X, Tan W, Jiang M, Lehrman MA, Rothermel BA, Lee AH, Lavandero S, Mammen P, Ferdous A, Gillette TG, Scherer PE, Hill JA. Article Cell (2014)
Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes Kuzmicic, Jovan; Parra, Valentina; Verdejo Hugo E.; López-Crisosto, Camila; Chiong, Mario; Garcia, Lorena; Jensen, Michael D.; Bernlohr, David A.; Castro Pablo F.,; Lavandero, Sergio Article ISI SCOPUS BIOCHEMICAL PHARMACOLOGY (2014)
Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death Parra, V; Moraga, F; Kuzmicic J.; López-Crisosto, C; Troncoso R.; Torrealba, N; Criollo, A; Diaz-Elizondo, J; Rothermel BA; Quest, AFG; Lavandero S. Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy pedrozo, Z; Torrealba, N; Fernandez, C.; Gatica, D; Toro, B; Quiroga, C; Rodríguez, AE; Sánchez G; Gillette, TG; Hill, JA; Donoso P.; Lavandero S. Article ISI SCOPUS Cardiovascular Research (2013)
Cell Death and Survival Through the Endoplasmic Reticulum-Mitochondrial Axis Bravo Sagua R; Rodríguez, AE; Kuzmicic J.; Gutiérrez T.; López-Crisosto, C; Quiroga, C; Diaz-Elizondo, J; Chiong M.; Gillette, TG; Rothermel BA; Lavandero S. Article ISI CURRENT MOLECULAR MEDICINE (2013)
Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3K gamma-Akt-AS160 in Skeletal Muscle Cells Osorio-Fuentealba, C; Contreras-Ferrat, AE; Altamirano F.; Espinosa, A.; Li, Q.; Niu, WY; Lavandero S.; Klip, A; Jaimovich E. Article ISI SCOPUS Diabetes (2013)
Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells Antileo, E; Garri, C; Tapia, V; Munoz, JP; Chiong M.; Nualart, F.; Lavandero S.; Fernandez, J; Nunez, MT Article ISI SCOPUS American Journal of Physiology - Gastrointestinal and Liver Physiology (2013)
Herp depletion protects from protein aggregation by up-regulating autophagy Quiroga, C; Gatica, D; Paredes, F; Bravo, R.; Troncoso R.; pedrozo, Z; Rodríguez, AE; Toro, B; Chiong M.; Vicencio, JM; hetz C.; Lavandero S. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Cell Research (2013)
Local Control of Nuclear Calcium Signaling in Cardiac Myocytes by Perinuclear Microdomains of Sarcolemmal Insulin-Like Growth Factor 1 Receptors Ibarra, C; Vicencio, JM; Estrada, M; Lin, YB; Rocco, P; Rebellato, P; Munoz, JP; Garcia-Prieto, J; Quest, AFG; Chiong M.; Davidson, SM; Bulatovic, I; Grinnemo, KH; Larsson, O; Szabadkai G.; Uhlen, P; Jaimovich E.; Lavandero S. Article ISI SCOPUS Circulation Research (2013)
Testosterone Increases GLUT4-Dependent Glucose Uptake in Cardiomyocytes Wilson, C; Contreras-Ferrat, A; Venegas, N.; Osorio-Fuentealba, C; Pavez, M.; Montoya, K; Duran, J; Maass, R.; Lavandero S.; Estrada, M Article ISI SCOPUS Journal of Cellular Physiology (2013)
TGF-beta 1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways Vivar, R; Humeres, C.; Ayala, P; Olmedo, I; Catalán M.; Garcia, L.; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2013)
A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway Zamorano S.; Rojas-Rivera, D; Lisbona, F; Parra, V; Court, F. A.; Villegas, R; Cheng E.H.; Korsmeyer S.J.; Lavandero S.; hetz C. Article ISI SCOPUS PLOS ONE (2012)
Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes Bustamante-Marin, X; Quiroga, C; Lavandero S.; Reyes, J.G.; Moreno, R.D. Article ISI SCOPUS Apoptosis (2012)
Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol Ayala, P; Montenegro, J.; Vivar, R; Letelier, A; Urroz P.A.; Copaja M; Pivet, D; Humeres, C.; Troncoso R.; Vicencio J.M.; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS Experimental and Molecular Pathology (2012)
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart Ibacache M.; Sánchez G; pedrozo, Z; Galvez, F; Humeres, C.; Echevarria, G; Duaso, J.; Hassi, M; Garcia, L.; Diaz-Araya, G; Lavandero S. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2012)
Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast Catalán M.; Smolic, C; Contreras, A; Ayala, P; Olmedo, I; Copaja M; Boza P.; Vivar, R; Avalos, Y; Lavandero S.; Velarde, V; Diaz-Araya, G Article ISI SCOPUS Toxicology and Applied Pharmacology (2012)
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics Bravo, R.; Gutiérrez T.; Paredes, F; Gatica, D; Rodríguez A.E.; pedrozo, Z; Chiong M.; Parra, V; Quest, A.F.G.; Rothermel, B. A.; Lavandero S. Article ISI SCOPUS International Journal of Biochemistry and Cell Biology (2012)
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy Troncoso R.; Vicencio J.M.; Parra, V; Nemchenko A.; Kawashima Y.; del Campo, A; Toro, B; Battiprolu P.K.; Aranguiz, P; Chiong M.; Yakar S.; Gillette, T. G.; Hill J.A.; Abel E.D.; LeRoith, D; Lavandero S. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2012)
ICDS 2011 meeting 'Signaling in cell death survival, proliferation and degeneration' Lockshin, RA; Smaili, SS; Lavandero S.; Zakeri, Z Article CELL DEATH AND DIFFERENTIATION (2012)
Impaired cardiac autophagy in patients developing postoperative atrial fibrillation Garcia, L.; Verdejo H.E.; Kuzmicic J.; Zalaquett R.; Gonzalez S.; Lavandero S.; Corbalan, R Article ISI SCOPUS JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2012)
Mayores niveles de ECA y Angiotensina II determinados genéticamente, se asocian a menor actividad del eje ECA2/angiotensina-(1-9) y mayor remodelamiento de la pared aórtica de ratas hipertensas Moya, Jackeline; Novoa, Ulises; Escudero, Nicolas; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiología (2012)
Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice Battiprolu P.K.; Hojayev B.; Jiang, N; Wang Z.V.; Luo X.; Iglewski, M; Shelton J.M.; Gerard R.D.; Rothermel, B. A.; Gillette, T. G.; Lavandero S.; Hill J.A. Article ISI SCOPUS Journal of Clinical Investigation (2012)
Mitochondria, Myocardial Remodeling, and Cardiovascular Disease Verdejo H.E.; del Campo, A; Troncoso R.; Gutiérrez T.; Toro, B; Quiroga, C; pedrozo, Z; Garcia, L.; Lavandero S.; Castro P.F.; Munoz, J. P. Article CURRENT HYPERTENSION REPORTS (2012)
NFAT5 Is Activated by Hypoxia: Role in Ischemia and Reperfusion in the Rat Kidney Villanueva, S.; Suazo, C; Santapau, D; Pérez F.; Quiroz M.; Carreno, J.E.; Illanes, S; Lavandero S.; Michea, L.; Irarrázabal C.E. Article ISI SCOPUS PLOS ONE (2012)
Protein Carbonylation and Adipocyte Mitochondrial Function Curtis J.M.; Hahn W.S.; Stone M.D.; Inda J.J.; Droullard D.J.; Kuzmicic J.P.; Donoghue M.A.; Long E.K.; Armien A.G.; Lavandero S.; Arriaga E.; Griffin T.J.; Bernlohr D.A. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Relationship between mechanical and metabolic dyssynchrony with left bundle branch block: Evaluation by 18-fluorodeoxyglucose positron emission tomography in patients with non-ischemic heart failure Castro P. ; Winter J.L.; Verdejo H.; Orellana P.; Quintana J.C.; greig d.; Enriquez A.; Sepulveda, L; Concepcion, R; Sepúlveda P.; Rossel V.; Chiong M.; Garcia, L.; Lavandero S. Article ISI SCOPUS Journal of Heart and Lung Transplantation (2012)
Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability Copaja M; Venegas, D; Aranguiz, P; Canales, J; Vivar, R; Avalos, Y; Garcia, L.; Chiong M.; Olmedo, I; Catalán M.; Leyton, L; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS Toxicology (2012)
Anabolic androgenic steroids and intracellular calcium signaling: A mini review on mechanisms and physiological implications. Vicencio JM; Estrada M; Galvis D; Bravo R; Contreras AE; Rotter D; Szadabkai G; Hill JA; Rothermel BA; Jaimovich E; Lavandero S Article Mini Rev Med Chem (2011)
Beta(2)-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation Aranguiz-Urroz, P; Canales, J; Copaja M; Troncoso R.; Vicencio, JM; Carrillo, C.; Lara, H; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2011)
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress Bravo, R.; Vicencio, JM; Parra, V; Troncoso R.; Munoz, JP; Bui, M; Quiroga, C; Rodríguez, AE; Verdejo, HE; Ferreira J.; Iglewski, M; Chiong M.; Simmen T.; Zorzano, A; Hill, JA; Rothermel BA; Szabadkai G.; Lavandero S. Article ISI SCOPUS Journal of Cell Science (2011)
Inhibition of autophagy by TAB2 and TAB3 Criollo, A; Niso-Santano, M; Malik, SA; Michaud, M; Morselli E.; Marino, G; Lachkar S; Arkhipenko, AV; Harper, F; Pierron, G; Rain JC; Ninomiya-Tsuji J.; Fuentes, JM; Lavandero S.; Galluzzi L.; Maiuri, MC; Kroemer G. Article ISI SCOPUS EMBO Journal (2011)
Left Atrial Dysfunction Is a Predictor of Postcoronary Artery Bypass Atrial Fibrillation: Association of Left Atrial Strain and Strain Rate Assessed by Speckle Tracking Gabrielli, L; Corbalan, R; Cordova S; Enriquez A.; Mc-Nab, P; Verdejo, HE; Godoy, I.; Zalaquett R.; Lavandero S. Article ISI SCOPUS Echocardiography (2011)
Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure Ocaranza, MP; Gabrielli, L; Mora I; Garcia, L.; Mcnab P.; Godoy, I.; Braun, S; Cordova S; Castro P. ; Novoa U.; Chiong M.; Lavandero S.; JALIL, JE Article ISI SCOPUS American Heart Journal (2011)
Mayor actividad de rho kinasa en leucocitos circulantes se asocia a estrés oxidativo y rigidez arterial en hipertensos diabéticos Gabrielli, Luigi; Berkovitz, Alejandro; Mora, Italo; Novoa, Ulises; Godoy, Ivan; MacNab, Paul; Córdova, Samuel; Padilla, Ivonne; Rigotti, Paola; Garcia, Lorena; Lavandero, Sergio; Ocaranza, Maria Paz; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2011)
Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension Ocaranza, MP; rivera, p; Novoa U.; Pinto, M; Gonzalez L.; Chiong M.; Lavandero S.; JALIL, JE Article ISI SCOPUS Journal of Hypertension (2011)
Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts Copaja M; Venegas, D; Aranguiz, P; Canales, J; Vivar, R; Catalán M.; Olmedo, I; Rodríguez, AE; Chiong M.; Leyton, L; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS Toxicology and Applied Pharmacology (2011)
Systemic Oxidative Stress and Endothelial Dysfunction is Associated With an Attenuated Acute Vascular Response to Inhaled Prostanoid in Pulmonary Artery Hypertension Patients Gabrielli, LA; Castro, PF; Godoy, I.; Mellado R.; Bourge, RC; Alcaino H; Chiong M.; greig d.; Verdejo, HE; Navarro M.; Lopez R.; Toro, B; Quiroga, C; Diaz-Araya, G; Lavandero S.; Garcia, L. Article ISI SCOPUS Journal of Cardiac Failure (2011)
Systemic vascular cell adhesion molecule-1 predicts the occurrence of post-operative atrial fibrillation Verdejo H.; Roldan, J; Garcia, L.; del Campo, A; Becerra E.; Chiong M.; Mellado R.; Garcia, A.; Zalaquett R.; Braun, S; Garayar B.; Gonzalez S.; Lavandero S.; Corbalan, R Article ISI SCOPUS INTERNATIONAL JOURNAL OF CARDIOLOGY (2011)
The complex interplay between mitochondrial dynamics and cardiac metabolism Parra, V; Verdejo H.; del Campo, A; Pennanen C.; Kuzmicic J.; Lavandero S.; Iglewski, M; Hill J.A.; Rothermel, B. A. Article ISI SCOPUS Journal of Bioenergetics and Biomembranes (2011)
The role of uric acid in heart failure Alcaino H; greig d.; Castro P. ; Verdejo H.; Mellado R.; Garcia, L.; Diaz-Araya, G; Quiroga, C; Chiong M.; Lavandero S. Article ISI REVISTA MEDICA DE CHILE (2011)
The role of uric acid in heart failure Ácido úrico: Una molécula con acciones paradójicas en la insuficiencia cardiaca Alcaino H; greig d.; Castro P. ; Verdejo H.; Mellado R.; Garcia, L.; Diaz-Araya, G; Quiroga, C; Chiong M.; Lavandero S. Article REVISTA MEDICA DE CHILE (2011)
Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters greig d.; Alcaino H; Castro, PF; Garcia, L.; Verdejo, HE; Navarro M.; Lopez R.; Mellado R.; Tapia, F; Gabrielli, LA; Nogerol C.; Chiong M.; Godoy, I.; Lavandero S. Article ISI SCOPUS Journal of Heart and Lung Transplantation (2011)
An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose Transporter 4 Translocation and Glucose Uptake in Cardiomyocytes Contreras-Ferrat, AE; Toro, B; Bravo, R.; Parra, V; Vásquez C.; Ibarra, C; Mears, D; Chiong M.; Jaimovich E.; Klip, A; Lavandero S. Article ISI SCOPUS Endocrinology (2010)
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro Ocaranza, MP; Lavandero S.; JALIL, JE; Moya, J; Pinto, M; Novoa U.; Apablaza F.; Gonzalez L.; Hernandez C.; Varas, M; Lopez R.; Godoy, I.; Verdejo H.; Chiong M. Article ISI SCOPUS Journal of Hypertension (2010)
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion pedrozo, Z; Sánchez G; Torrealba, N; Valenzuela R.; Fernandez, C.; Hidalgo C.; Lavandero S.; Donoso P. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2010)
Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells Niu, WY; Bilan, PJ; Ishikura, S; Schertzer, JD; Contreras-Ferrat, A; Fu, ZX; Liu, J; Boguslavsky, S; Foley, KP; Liu, Z; Li, JR; Chu, GL; Panakkezhum, T; Lopaschuk, GD; Lavandero S.; Yao, Z; Klip, A Article ISI SCOPUS American Journal of Physiology - Endocrinology and Metabolism (2010)
Determinaciones de niveles de creatina y lípidos mediante espectroscopia por resonancia magnética en miocardio de pacientes con insuficiencia cardiaca no isquémica Winter, José Luis; Castro, Pablo; Meneses, Luis; CHALHUB, MÓNICA; Verdejo, Hugo; Greig, Douglas; Gabrielli, Luigi; Chiong, Mario; Concepción, Roberto; MELLADO, ROSEMERIE; HERNÁNDEZ, CLAUDIA; Uribe, Sergio; Lavandero, Sergio Article SCIELO REVISTA MEDICA DE CHILE (2010)
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes Marambio P.; Toro, B; Sanhueza C.; Troncoso R.; Parra, V; Verdejo H.; Garcia, L.; Quiroga, C; Munafo, D; Diaz-Elizondo, J; Bravo, R.; Gonzalez, MJ; Diaz-Araya, G; pedrozo, Z; Chiong M.; Colombo, MI; Lavandero S. Article ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2010)
Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro P. ; Gabrielli, L; Verdejo H.; greig d.; Llevaneras, S; Hernandez C.; Godoy, I.; Jalil J.E.; Quintana J.C.; Orellana P.; Mellado R.; Concepcion, R; Sepulveda, L; Vukasovic J.L.; Garcia, L.; Pizarro M.; Pivet, D; Carrillo, C.; Tapia, F; Navarro M.; Troncoso R.; Chiong M.; Lavandero S.; Baraona F. Article SCOPUS Revista Medica de Chile (2010)
Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients Stehr C.B.; Carvajal, C. A.; Mosso L.; Becerra E.; Fardella C.E.; Mellado R.; Ocaranza M.P.; Jalil J.; Solis, M; Garcia, L.; Lavandero S. Article ISI SCOPUS Journal of Hypertension (2010)
Insulin-Mediated GLUT4 Translocation Requires Intracellular and Extracellular Calcium and is Impaired by Short-Term High Fat Feeding Contreras-Ferrat, A; Wende, AR; Klip, A; Lavandero S.; Abel, ED Article CIRCULATION (2010)
Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide Munoz, JP; Chiong M.; Garcia, L.; Troncoso R.; Toro, B; pedrozo, Z; Diaz-Elizondo, J; Salas, D.; Parra, V; Nunez, MT; Hidalgo C.; Lavandero S. Article ISI SCOPUS Free Radical Biology and Medicine (2010)
La sobreexpresión del gen de enzima convertidora de angiotensina homóloga (ECA2) revierte la hipertensión arterial y el remodelado cardíaco experimental Ramos, Elizabeth; Herrera, Alejandro; Moya, Jackeline; Apablaza, Felipe; Godoy, Ivan; Jalil, Jorge; Lavandero, Sergio; Chiong, Mario; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiología (2010)
Menores niveles tisulares de la enzima convertidora de angiotensina I homologa (ECA-2) y angiotensina-(1-9) están asociados a mayor remodelamiento de la pared aórtica de ratas hipertensas Ocaranza, Maria Paz; Moya, Jackeline; Pinto, Melissa; Escudero, Nicolas; Valenzuela, Francisco; Varas, Manuel; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2010)
Mitochondria fine-tune the slow Ca2+ transients induced by electrical stimulation of skeletal myotubes Eisner V.; Parra, V; Lavandero S.; Hidalgo C.; Jaimovich E. Article ISI SCOPUS Cell Calcium (2010)
Mitochondrial Fission and Autophagy in the Normal and Diseased Heart Iglewski, M; Hill, JA; Lavandero S.; Rothermel BA Article ISI SCOPUS Current Hypertension Reports (2010)
Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure Determinaciones de niveles de creatina y lípidos mediante espectroscopia por resonancia magnética en miocardio de pacientes con insuficiencia cardiaca no isquémica Winter J.L.; Castro P. ; Chalhub M.; Verdejo H.; greig d.; Gabrielli, L; Hernandez C.; Uribe, S.; Meneses L.; Chiong M.; Lavandero S.; Concepcion, R; Mellado R. Article REVISTA MEDICA DE CHILE (2010)
Niveles aumentados de estrés oxidativo se asocian a disfunción endotelial periférica y respuesta vascular pulmonar disminuida frente a vasodilatadores en pacientes con hipertensión pulmonar Gabrielli, Luigi; Castro, Pablo; Chiong, Mario; Alcaino, Hernan; Verdejo, Hugo; Navarro, Mario; Greig, Douglas; Godoy, Ivan; Toro, Barbra; Quiroga, Clara; Diaz-Araya, Guillermo; Lavandero, Sergio; Garcia, Lorena Article SCIELO Revista chilena de cardiología (2010)
Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress Chiong M.; Parra, V; Eisner V.; Ibarra, C; Maldonado, C; Criollo, A; Bravo, R.; Quiroga, C; Contreras, A; Vicencio, JM; Cea, P; Bucarey, JL; Molgó J.; Jaimovich E.; Hidalgo C.; Kroemer G.; Lavandero S. Article ISI SCOPUS Apoptosis (2010)
The IKK complex contributes to the induction of autophagy Criollo, A; Senovilla, L; Authier, H; Maiuri, MC; Morselli E.; Vitale, I; Kepp, O; Tasdemir, E; Galluzzi L.; Shen, SS; Tailler, M; Delahaye, N; Tesniere, A; De Stefano, D; Ben-Younes, A; Harper, F; Pierron, G; Lavandero S.; Zitvogel, L.; Israel, A.; Baud, V; Kroemer G. Article ISI SCOPUS EMBO Journal (2010)
(TTA)n Polymorphism in 3-Hydroxy-3-Methylglutaryl-Coenzyme A and Response to Atorvastatin in Coronary Artery Disease Patients Noriega V.; Pennanen C.; Sanchez, MP; Chiong M.; Llancaqueo, M; Lavandero S.; Prieto, JC Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death Triggered by Angiotensin II Aranguiz-Urroz, P; Soto, D; Contreras, A; Troncoso R.; Chiong M.; Montenegro, J.; Venegas, D; Smolic, C; Ayala, P; Thomas, WG; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS AMERICAN JOURNAL OF HYPERTENSION (2009)
El tratamiento con atorvastatina reduce la actividad de xantina-oxidasa unida al endotelio en pacientes con insuficiencia cardíaca crónica: ¿Un posible nuevo efecto pleiotrópico? Alcaino, Hernan; Castro, Pablo; Greig, Douglas; Verdejo, Hugo; Chiong, Mario; Garcia, Lorena; Gabrielli, Luigi; Diaz-Araya, Guillermo; Vukasovic, José Luis; Godoy, Ivan; Lavandero, Sergio Article SCIELO Revista chilena de cardiología (2009)
Ex vivo method to visualize and quantify vascular networks in native and tissue engineered skin Egana, JT; Condurache, A; Lohmeyer, J; Kremer, M; Stockelhuber, B; Lavandero S.; Machens, HG Article ISI SCOPUS LANGENBECKS ARCHIVES OF SURGERY (2009)
Gln(27)-> Glu beta(2)-Adrenergic Receptor Polymorphism in Heart Failure Patients: Differential Clinical and Oxidative Response to Carvedilol Troncoso R.; Moraga, F; Chiong M.; Roldan, J; Bravo, R.; Valenzuela R.; Diaz-Araya, G; del Campo, A; Sanhueza C.; Rodríguez A.; Vukasovic, JL; Mellado R.; greig d.; Castro, PF; Lavandero S. Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alpha v beta 3 integrin that activates PKC alpha and RhoA Avalos, AM; Valdivia, AD; Muñoz, N.; Herrera-Molina, R; Tapia, JC; Lavandero S.; Chiong M.; Burridge, K; Schneider, P.; Quest, AFG; Leyton, L Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2009)
Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species Rojas-Rivera, D; Diaz-Elizondo, J; Parra, V; Salas, D.; Contreras, A; Toro, B; Chiong M.; Olea Azar C.; Lavandero S. Article ISI SCOPUS FEBS LETTERS (2009)
Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway Altamirano F.; Oyarce, C; Silva P.; Toyos, M; Wilson, C; Lavandero S.; Uhlen, P; Estrada, M Article ISI SCOPUS JOURNAL OF ENDOCRINOLOGY (2009)
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 Vicencio, JM; Ortiz, C.; Criollo, A; Jones, AWE; Kepp, O; Galluzzi L.; Joza, N; Vitale, I; Morselli E.; Tailler, M; Castedo, M; Maiuri, MC; Molgó J.; Szabadkai G.; Lavandero S.; Kroemer G. Article ISI SCOPUS CELL DEATH AND DIFFERENTIATION (2009)
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling Munoz, JP; Collao, A; Chiong M.; Maldonado, C; Adasme, T.; CARRASCO L.; Ocaranza, P; Bravo, R.; Gonzalez L.; Diaz-Araya, G; Hidalgo C.; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
The use of glandular-derived stem cells to improve vascularization in scaffold-mediated dermal regeneration Egana, JT; Danner, S; Kremer, M; Rapoport, DH; Lohmeyer, JA; Dye, JF; Hopfner, U; Lavandero S.; Kruse, C; Machens, HG Article ISI SCOPUS BIOMATERIALS (2009)
Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity Ribeiro, CH; Lopez, NC; Ramirez, GA; Valck, CE; Molina, MC; Aguilar, L; Rodríguez, M.; Maldonado I.; Martínez R.; González C; Troncoso R.; Lavandero S.; Gingras, AR; Schwaeble, W; Ferreira A. Article ISI SCOPUS MOLECULAR IMMUNOLOGY (2009)
Use of Human Mesenchymal Cells to Improve Vascularization in a Mouse Model for Scaffold-Based Dermal Regeneration Egana, JT; Fierro, FA; Kruger, S; Bornhauser, M; Huss, R; Lavandero S.; Machens, HG Article ISI SCOPUS TISSUE ENGINEERING PART A (2009)
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells Villena J.; Henríquez M; Torres V.; Moraga, F; Diaz-Elizondo, J; Arredondo, C; Chiong M.; Olea Azar C.; Stutzin A.; Lavandero S.; Quest, AFG Article ISI SCOPUS FREE RADICAL BIOLOGY AND MEDICINE (2008)
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis Parra, V; Eisner V.; Chiong M.; Criollo, A; Moraga, F; Garcia, A.; Haertel, S.; Jaimovich E.; Zorzano, A; Hidalgo C.; Lavandero S. Article ISI SCOPUS CARDIOVASCULAR RESEARCH (2008)
Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism Soto, MC; Valenzuela R.; Saldaña A.; Ocaranza, MP; JALIL, JE; Vio, C; Lijnen, P; Ordenes, GE; Sanchez, RV; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2008)
Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes Navarro P.; Chiong M.; Volkwein, K; Moraga, F; Ocaranza, MP; JALIL, JE; Lim, SW; Kim, JA; Kwon, HM; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor Vivar, R; Soto C.; Copaja M; Mateluna, F; Aranguiz, P; Munoz, JP; Chiong M.; Garcia, L.; Letelier, A; Thomas, WG; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2008)
Pleiotropic effects of atorvastatin in heart failure: Role in oxidative stress, inflammation, endothelial function, and exercise capacity Castro, PF; Miranda, R.; Verdejo, HE; greig d.; Gabrielli, LA; Alcaino H; Chiong M.; Bustos C.; Garcia, L.; Mellado R.; Vukasovic, JL; Godoy, I.; Lavandero S. Article ISI SCOPUS JOURNAL OF HEART AND LUNG TRANSPLANTATION (2008)
Senescence, apoptosis or autophagy? Vicencio, JM; Galluzzi L.; Tajeddine, N; Ortiz, C.; Criollo, A; Tasdemir, E; Morselli E.; Ben-Younes, A; Maiuri, MC; Lavandero S.; Kroemer G. Article ISI SCOPUS GERONTOLOGY (2008)
Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure Alcaino H; greig d.; Chiong M.; Verdejo H.; Miranda, R.; Concepcion, R; Vukasovic, JL; Diaz-Araya, G; Mellado R.; Garcia, L.; Salas, D.; Gonzalez L.; Godoy, I.; Castro P. ; Lavandero S. Article ISI SCOPUS EUROPEAN JOURNAL OF HEART FAILURE (2008)
Subclinical endothelial inflammation markers in a family with type I familial hyperaldosteronism caused by a de novo mutation Stehr, CB; Carvajal, CA; Lacourt, P; Alcaino H; Mellado R.; Cattani, A; Mosso, LM; Lavandero S.; Fardella, CE Article ISI REVISTA MEDICA DE CHILE (2008)
Mitochondrial control of cell death induced by hyperosmotic stress Criollo, A; Galluzzi L.; Maiuri, MC; Tasdemir, E; Lavandero S.; Kroemer G. Article ISI SCOPUS APOPTOSIS (2007)
Regulation of autophagy by the inositol trisphosphate receptor Criollo, A; Maiuri, MC; Tasdemir, E; Vitale, I; Fiebig, AA; Andrews, D; Molgó J.; Díaz, J; Lavandero S.; Harper, F; Pierron, G; di Stefano, D; Rizzuto, R; Szabadkai G.; Kroemer G. Article ISI SCOPUS CELL DEATH AND DIFFERENTIATION (2007)
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I-converting enzyme levels rivera, p; Ocaranza, MP; Lavandero S.; JALIL, JE Article ISI HYPERTENSION (2007)
The inositol trisphosphate receptor in the control of autophagy Criollo, A; Vicencio, JM; Tasdemir, E; Maiuri, MC; Lavandero S.; Kroemer G. Article ISI SCOPUS AUTOPHAGY (2007)
Tumor necrosis factor-? activates nuclear factor-?B but does not regulate progesterone production in cultured human granulosa luteal cells Gonzalez-Navarrete, F; Morales P.; Castro O.; Pommer R.; Devoto L.; Eisner V.; Quiroga, C; Lavandero S. Article GYNECOLOGICAL ENDOCRINOLOGY (2007)
Tumor necrosis factor-alpha activates nuclear factor-kappa B but does not regulate progesterone production in cultured human granulosa luteal cells Gonzalez-Navarrete, F; Eisner V.; Morales P.; Castro O.; Pommer R.; Quiroga, C; Lavandero S.; Devoto L. Article ISI SCOPUS GYNECOLOGICAL ENDOCRINOLOGY (2007)
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism Ocaranza, MP; Palomera, C; Román M.; Bargetto, J; Lavandero S.; JALIL, JE Article ISI SCOPUS LIFE SCIENCES (2006)
Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat Ocaranza, MP; Godoy, I.; JALIL, JE; Varas, M; Collantes, P; Pinto, M; Román M.; Ramírez C.; Copaja M; Diaz-Araya, G; Castro P. ; Lavandero S. Article ISI SCOPUS HYPERTENSION (2006)
Hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death Eisner V.; Quiroga, C; Criollo, A; Eltit, JM; Chiong M.; Parra, V; Hidalgo K.; Toro, B; Diaz-Araya, G; Lavandero S. Article ISI SCOPUS FEBS LETTERS (2006)
Hyperosmotic stress-dependent NF kappa B activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes Eisner V.; Criollo, A; Quiroga, C; Olea Azar C.; Santibanez, JF; Troncoso R.; Chiong M.; Diaz-Araya, G; Foncea, R; Lavandero S. Article ISI SCOPUS FEBS LETTERS (2006)
Membrane electrical activity elicits inositol 1,4,5-trisphosphate-dependent slow Ca2+ signals through a G beta gamma/phosphatidylinositol 3-kinase gamma pathway in skeletal myotubes Eltit, JM; Garcia, AA; Hidalgo J.; LIBERONA, JL; Chiong M.; Lavandero S.; Maldonado E.; Jaimovich E. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Reactive oxygen species inhibit hyposmotic stress-dependent volume regulation in cultured rat cardiomyocytes Diaz-Elizondo, J; Chiong M.; Rojas-Rivera, D; Olea Azar C.; Kwon, HM; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes Vicencio, JM; Ibarra, C; Estrada, M; Chiong M.; Soto, D; Parra, V; Diaz-Araya, G; Jaimovich E.; Lavandero S. Article ISI SCOPUS ENDOCRINOLOGY (2006)
Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic heart failure Castro P. ; Vukasovic, JL; Chiong M.; Diaz-Araya, G; Alcaino H; Copaja M; Valenzuela R.; greig d.; Perez, O; Corbalan, R; Lavandero S. Article ISI SCOPUS EUROPEAN JOURNAL OF HEART FAILURE (2005)
Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure Castro, PF; Mc-Nab, P; Quintana, JC; Bittner, A; greig d.; Vergara, I; Vukasovic, JL; Corbalan, R; Copaja M; Diaz-Araya, G; Chiong M.; Troncoso R.; Alcaino H; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2005)
Eplerenone blocks nongenomic effects of aldosterone on the Na+/H+ exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels Michea, L.; Delpiano, AM; Hitschfeld, C; Lobos, L; Lavandero S.; Marusic, ET Article SCOPUS ENDOCRINOLOGY (2005)
IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB Maldonado, C; Cea, P; Adasme, T.; Collao, A; Diaz-Araya, G; Chiong M.; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels JALIL, JE; Pérez, A.; Ocaranza, MP; Bargetto, J; Galaz, A.; Lavandero S. Article ISI SCOPUS HYPERTENSION (2005)
Oxidative stress in pericardial fluid and plasma and its association with ventricular function Vukasovic, JL; Moraga, F; Diaz-Araya, G; Turner E.; Chiong M.; Uriarte, P; Florenzano, F; Lavandero S. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CARDIOLOGY (2005)
Perindopril regulates ?-agonist-induced cardiac apoptosis Galvez A.S.; Fiedler J.L.; Ocaranza M.P.; Lavandero S.; Jalil J.E.; Diaz-Araya, G Article SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2005)
Perindopril regulates beta-agonist-induced cardiac apoptosis Galvez, AS; Fiedler, JL; Ocaranza, MP; JALIL, JE; Lavandero S.; Diaz-Araya, G Article ISI JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2005)
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Castro P. ; Perez, O; greig d.; Diaz-Araya, G; Moraga, F; Chiong M.; Troncoso R.; Padilla I.; Vukasovic, JL; Corbalan, R; Lavandero S. Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2004)
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés oxidativo en pacientes con insuficiencia cardíaca crónica Castro P. ; Perez, O; greig d.; Padilla I.; Corbalan, R; Diaz-Araya, G; Moraga, F; Chiong M.; Troncoso R.; Lavandero S.; Vukasovic J.L. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2004)
Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells Rodriguez, DA; Moncada, C; Nunez, MT; Lavandero S.; Ponnappa, BC; Israel, Y Article ISI ALCOHOL (2004)
Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes Ibarra, C; Estrada, M; CARRASCO L.; Chiong M.; LIBERONA, JL; Cárdenas C; Diaz-Araya, G; Jaimovich E.; Lavandero S. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans JALIL, JE; Ocaranza, MP; Oliveri, C; Cordova S; Godoy, I.; Chamorro, G; Braun, S; Fardella, C.; Michel, JB; Lavandero S. Article ISI SCOPUS JOURNAL OF HUMAN HYPERTENSION (2004)
Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats Ocaranza, MP; Diaz-Araya, G; Carreño JE; Muñoz D; Riveros, JP; JALIL, JE; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis - Differential effects of sorbitol and mannitol Galvez, AS; Ulloa, JA; Chiong M.; Criollo, A; Eisner V.; Barros, LF; Lavandero S. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
IGF-1 modulation of rat cardiac fibroblast behavior and gene expression is age-dependent Diaz-Araya, G; Borg, TK; Lavandero S.; Loftis, MJ; Carver, W Article ISI SCOPUS CELL COMMUNICATION AND ADHESION (2003)
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-1-converting enzyme deletion/deletion genotype JALIL, JE; Palomera, C; Ocaranza, MP; GODOY, L.; Román M.; Chiong M.; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2003)
Relation between oxidative stress, catecholamines, and impaired chronotropic response to exercise in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy Castro, PF; greig d.; Perez, O; Moraga, F; Chiong M.; Diaz-Araya, G; Padilla I.; Nazzal C.; JALIL, JE; Vukasovic, JL; Moreno, M.; Corbalan, R; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2003)
Angiotensin I-converting enzyme gene polymorphism influences chronic hypertensive response in the rat Goldblatt model Ocaranza, MP; Piddo, AM; Faundez, P; Lavandero S.; JALIL, JE Article ISI SCOPUS JOURNAL OF HYPERTENSION (2002)
Angiotensin I-converting enzyme insertion/deletion polymorphism and adrenergic response to exercise in hypertensive patients Jalil J.E.; Cordova S; Ocaranza M.P.; Schumacher, E; Braun, S; Chamorro, G; Fardella, C.; Lavandero S. Article Medical Science Monitor (2002)
Effects of early decrease in oxidative stress after medical therapy in patients with class IV congestive heart failure Castro, PF; Diaz-Araya, G; Nettle, D; Corbalan, R; Perez, O; Nazzal C.; Larrain, G; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2002)
Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis Ocaranza, MP; Diaz-Araya, G; Chiong M.; Muñoz D; Riveros, JP; Ebensperger, R; Sabat, S; Irarrázaval P.; JALIL, JE; Lavandero S. Article ISI SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2002)
Oxidative stress after reperfusion with primary coronary angioplasty: Lack of effect of glucose-insulin-potassium infusion Diaz-Araya, G; Nettle, D; Castro P. ; Miranda F.; greig d.; Campos X; Chiong M.; Nazzal C.; Corbalan, R; Lavandero S. Article ISI SCOPUS CRITICAL CARE MEDICINE (2002)
Persistence of oxidative stress after heart tranplantation: A comparative study of patients with heart transplant versus chronic stable heart failure Perez, O; Castro P. ; Diaz-Araya, G; Nettle, D; Moraga, F; Chiong M.; Jalil J.; Zalaquett R.; Moran S.; Becker P.; Corbalan, R; Lavandero S. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2002)
Persistence of oxidative stress after heart transplantation: A comparative study of patients with heart transplant versus chronic stable heart failure Perez, O; Castro P. ; Diaz-Araya, G; Nettle, D; Moraga, F; Chiong M.; Jalil J.; Zalaquett R.; Moran S.; Becker P.; Corbalan, R; Lavandero S. Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2002)
A rapid and strong apoptotic process is triggered by hyperosmotic stress in cultured rat cardiac myocytes Galvez A.; MORALES, MP.; Eltit, JM; Ocaranza, P; CARRASCO L.; Campos X; Sapag-Hagar, M; Diaz-Araya, G; Lavandero S. Article ISI SCOPUS CELL AND TISSUE RESEARCH (2001)
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat Oliveri, C; Ocaranza, MP; Campos X; Lavandero S.; JALIL, JE Article ISI HYPERTENSION (2001)
Early prevention of experimental left ventricular hypertrophy in experimental hypertension and angiotensin II levels Galvez A.; Ocaranza, MP; Lavandero S.; JALIL, JE Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2001)
Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes Foncea, R; Galvez A.; Pérez V; MORALES, MP.; Calixto, A; Meléndez J.; Gonzalez-Jara, F; Diaz-Araya, G; Sapag-Hagar, M; Sugden, PH; LeRoith, D; Lavandero S. Article ISI BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress MORALES, MP.; Galvez A.; Eltit, JM; Ocaranza, P; Diaz-Araya, G; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat Jalil J.E.; Ebensperger, R; Meléndez J.; Acevedo, E; Sapag-Hagar, M; Gonzalez-Jara, F; Galvez A.; Perez-Montes V.; Lavandero S. Article LIFE SCIENCES (1999)
Prevalence of the angiotensin I converting enzyme insertion/deletion polymorphism, plasma angiotensin converting enzyme activity, and left ventricular mass in a normotensive Chilean population Jalil J.E.; Piddo A.M.; Cordova S; Chamorro, G; Braun, S; Jalil, R; Vega, J; Jadue'P L.; Lavandero S.; Lastra P. Article AMERICAN JOURNAL OF HYPERTENSION (1999)
Effect of inhibitors of signal transduction on IGF-1-induced protein synthesis associated with hypertrophy in cultured neonatal rat ventricular myocytes Lavandero S.; Foncea, R; Pérez V; Sapag-Hagar, M Article FEBS LETTERS (1998)
In vivo and in vitro evidence of basic fibroblast growth factor action in mouse mammary gland development Lavandero S.; Chappuzeau A.; Sapag-Hagar, M; Oka, T. Article FEBS LETTERS (1998)
Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy Ebensperger, R; Acevedo, E; Meléndez J.; Sapag-Hagar, M; Lavandero S.; Corbalan, R; Acevedo M.; Jalil J.E. Article BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (1998)
IGF-1 activates polyphosphoinositide hydrolysis, protein kinase C isoforms and ERK pathway in cultured neonatal rat cardiac myocytes Lavandero S.; Ferez V.; Foncea, R; Sapag-Hagar, M; Leroilh D. Article FASEB JOURNAL (1997)
Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes Foncea, R; Sapag-Hagar, M; Lavandero S.; Andersson M.; Ketterman A.; Sugden P.H.; Blakesley V.; LeRoith, D Article JOURNAL OF BIOLOGICAL CHEMISTRY (1997)
Omeprazole, a specific gastric secretion inhibitor on oxynticopeptic cells, reduces gizzard erosion in broiler chicks fed with toxic fish meals Hinrichsen J.P.; Neira M.; López C.; Chiong M.; Ocaranza M.P.; Gallardo R.; Rutman, M; Blamey, J.; Lavandero S. Article Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology (1997)
Cyclic AMP dependent protein kinase and mechanical heart function in ventricular hypertrophy induced by pressure overload or secondary to myocardial infarction Piddo A.M.; Sanchez M.I.; Sapag-Hagar, M; Corbalan, R; Foncea, R; Ebensperger, R; Godoy, I.; Meléndez J.; Jalil J.E.; Lavandero S. Article JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (1996)
Synthesis and pharmacological effects of 3-methyl tyrphostin (2-cyano- 3-[4-hydroxyphenyl]-2-butenethioamide): A new protein tyrosine kinase inhibitor Centella, C; De La Pena A.M.; Medina, J; Sapag-Hagar, M; Meléndez J.; Lavandero S.; Ocaranza M.P.; Escobedo, J Article Am J Therapeuthics (1996)
A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF Fernanda Sanhueza-Olivares; Troncoso, Mayarling Francisca; Pino-De la Fuente, Francisco; Martinez, Javiera; Riquelme, Jaime; Norambuena, Ignacio; Villa, Monica; Castro, Pablo F.; Chiong M.; Lavandero S. Article FRONTIERS IN ENDOCRINOLOGY
Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes Kretschmar C.; Peña, Daniel; Hernando, Cecilia; Hernandez, Nadia; Molina, Alfredo; Hernández-Cáceres, María Paz; Budini, Mauricio; Morselli, Eugenia; Parra, Valentina; Troncoso, Rodrigo; Criollo, Alfredo; Lavandero S. Article FRONTIERS IN ENDOCRINOLOGY
VCAM-1 as a predictor biomarker in cardiovascular disease Troncoso, Mayarling Francisca; Ortiz-Quintero, Jafet; Garrido-Moreno, Valeria; Sanhueza-Olivares, Fernanda; Guerrero, Alejandra.; Chiong, Mario; Castro Pablo F.,; Garcia, Lorena; Gabrielli, Luigi; Corbalan, Ramon; Garrido, Luis; Lavandero S. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE


Glutathione depletion in spermatogonia-type germ cells: Autophagy and Ago2 function Mancilla, H.; Cereceda, K.; Vander Stelt, K; Villarroel-Espindola, F; Schraivogel, D; Meister G.; Lavandero S.; Slebe, JC; Concha, II Abstract ISI FEBS JOURNAL (2015)
FoxO1 switches energy metabolism and stimulates mitochondrial fission in myocardial insulin resistance. Quiroga, C; Acuña F.; Vasquez-Trincado, C; Pavez, M.; Gomez, T; Estrada, M; Verdejo H.; Castro P. ; Hill J.; Lavandero S. Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2014)
Angiotensin-(1-9) Decreases Hypertension and Vascular Damage by Inhibiting Rhoa/rock Activity in Doca Hypertensive Rats Ocaranza, MP; Villegas, B; Moya, J; Barrientos, V; Novoa U.; Perez, O; Walkowiak, S; Chiong M.; Lavandero S.; Michea, L.; Jalil J. Abstract ISI HYPERTENSION (2013)
FoxO1 Ablation Rescues Metabolic Stress-induced Cardiac Remodeling Battiprolu, PK; Morales, CR; Baker L.; pedrozo, Z; Li, DL; Nguven, A; Jiang, N; Shelton, JM; Gillette, TG; Lavandero S.; Hill, JA Abstract ISI CIRCULATION (2013)
Germ cell autophagy: adaptive response to glutathione deficiency Mancilla, H.; Cereceda, K.; Maldonado R.; Villarroel-Espindola, F; de Oca, MM; Angulo, C; Castro MA; Slebe, JC; Vera, JC; Lavandero S.; Concha, II Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2013)
HDAC-Dependent Regulation of Pathological Hypertrophy Morales, CR; pedrozo, Z; Li, DL; May, HI; Jiang, N; Lavandero S.; Gillette, TG; Hill, JA Abstract ISI CIRCULATION (2013)
Herp protects Hela cells from oxidative stress-induced cell death Diaz, FIP; Gatica, D; Quiroga, C; Parra, V; Bravo, R.; Troncoso R.; Torrealba, N; Navarro M.; Jaimovish, E; Lavandero S. Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2013)
Insulin Induces both H2O2 Production and IP3-Dependent Mitochondria Ca2+ Uptake. H2O2 Oxidizes RyR to Elicit Ca2+ Release and GLUT4 Translocation in Skeletal Muscle Cells Contreras-Ferrat, AE; Llanos P.; Osorio C.; Espinosa, A.; Vásquez C.; Lavandero S.; Klip, A; Jaimovich E. Abstract BIOPHYSICAL JOURNAL (2013)
Polycystin 2 is Required for Stress-induced Activation of Autophagy in Heart Criollo, A; pedrozo, Z; Jiang, N; Luo X.; Gillette, TG; Lavandero S.; Hill, JA Abstract ISI CIRCULATION (2013)
Polycystin-1 Regulates Cardiac Hypertrophy via the L-type Calcium Channel pedrozo, Z; Criollo, A; Gillette, TG; Lavandero S.; Hill, JA Abstract ISI CIRCULATION (2013)
Effect of proinflammatory cytokines on mitochondrial function in 3T3-L1 adipocytes Kuzmicic, JP; Hahn, W.; Burrill, J; Lavandero S.; Bernlohr, D Abstract ISI FASEB JOURNAL (2012)
NAD(P)H oxidase-dpendent H2O2 production and RyR-IP3R activation are required for insulin induced GLUT4 translocation and glucose uptake in skeletal muscle cells Contreras-Ferrat, A; Vásquez C.; Espinosa, A.; Lavandero S.; Klip, A; Jaimovich E. Abstract ISI FASEB JOURNAL (2012)
New insights into insulin action in the heart Lavandero S. Abstract ISI FEBS JOURNAL (2012)
Angiotensin-(1-9) Prevents Cardiomyocyte Hypertrophy Through Calcium Influx Dependent Pathway Ocaranza, MP; Hechenleitner, J; Gonzalez L.; Chiong M.; Jalil J.; Lavandero S. Abstract HYPERTENSION (2011)
Angiotensin-(1-9) Prevents the Cardiovascular Pathological Remodeling Induced by Angiotensin II In Vivo Ocaranza, MP; Lagos T.; Moya, J; Morales C. ; Gonzalez L.; Novoa U.; Chiong M.; Lavandero S.; Jalil J. Abstract HYPERTENSION (2011)
Evidence of impaired cardiac autophagic flux in patients developing post-operative atrial fibrillation Kuzmicic J.; Verdejo H.; Garcia, L.; Gonzalez S.; pedrozo, Z; Toro, B; Zalaquett R.; Chiong M.; Lavandero S.; Corbalan, R Abstract EUROPEAN HEART JOURNAL (2010)
Persistent Activation of FoxO Contributes to Insulin Resistance and Diabetic Cardiomyopathy Battiprolu, PK; Spellman, JW; Chen, TC; Luo X.; Jiang, N; Ferdous, A.; Rothermel BA; Gillette, TG; Lavandero S.; Hill, JA Abstract ISI CIRCULATION (2010)
Increased Oxidative Stress Correlates With Pulmonary Vascular Response to Vasodilators in Pulmonary Artery Hypertension Patients Castro P. ; Gabrielli, L; Fasce, F; Verdejo H.; greig d.; Llevaneras, S; Ferrada M.; Hernandez C.; Godoy, I.; Garcia, L.; Mellado R.; Sepúlveda P.; Lavandero S. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
MITOCHONDRIA MODULATE INTRACELLULAR CALCIUM SIGNALS THAT CONTROL ATP TRANSIENTS INDUCED BY ELECTRICAL STIMULATION OF SKELETAL MYOTUBES Eisner, VR; Parra, V; Lavandero S.; Hidalgo C.; Jaimovich E. Abstract ISI JOURNAL OF PHYSIOLOGICAL SCIENCES (2009)
Use of pancreas-derived stem cells to improve vascularization in skin tissue engineering Egana, JT; Danner, S; Kremer, M; Rapoport, DH; Lavandero S.; Kruse, C; Machens, HG Abstract ISI TISSUE ENGINEERING PART A (2008)
Angiotensin II triggers apoptosis in cardiac fibroblast but not in myofibroblast overexpressing the type 1 receptor Diaz-Araya, GA; Sanchez, RV; Soto C.; Copaja M; Mateluna, F; Aranguiz, P; Munoz, JP; Chiong M.; Thomas, WG; Lavandero S. Abstract FEBS JOURNAL (2007)
Effects of atorvastatin therapy in heart failure: Oxidative stress, inflammation, endothelial dysfunction and exercise capacity Miranda, R.; Castro P. ; Verdejo H.; greig d.; Alcaino H; Bustos C.; Vukasovic, JL; Godoy, I.; Diaz-Araya, G; Lavandero S. Abstract ISI JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)
Inflammation and endothelial dysfunction in patients with chronic heart failure greig d.; Castro P. ; Miranda, R.; Concepcion, R; Chiong M.; Alcaino H; Diaz-Araya, G; Bustos C.; Verdejo H.; Lavandero S. Abstract ISI EUROPEAN HEART JOURNAL (2007)
Mitochondrial Ca2+ transients upon electrical stimulation of skeletal myotubes Eisner V.; Pavarotti, M; Hidalgo C.; Lavandero S.; Jaimovich E. Abstract ISI BIOPHYSICAL JOURNAL (2007)
Up-regulation of ACE2 by enalapril is associated to lower cardiac remodeling in myocardial infarcted rat Ocaranza, MP; Varas, M; Godoy, I.; Pinto, M; Román M.; Nilo, F.; Mackenzie, D; Alarcon M.; Jalil J.; Lavandero S. Abstract ISI FASEB JOURNAL (2007)
Activity of metalloproteinase-9 is related to oxidative stress in the acute coronary syndrome Bittner, A; Castro P. ; Perez, O; Alcaino H; Troncoso R.; Chiong M.; Diaz-Araya, G; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2006)
Carvedilol corrects interventricular and interventricular dyssynchrony in chronic heart failure. Castro, PF; Mc-Nab, P; Bittner, A; greig d.; Quintana, JC; Chiong M.; Diaz-Araya, G; Valenzuela R.; Vergara, I; Corbalan, R; Lavandero S. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)
Apoptosis induced by hyperosmotic stress Eisner V.; Quiroga, C; Criollo, A; Olea, C; Diaz-Araya, G; Chiong M.; Lavandero S. Abstract FREE RADICAL BIOLOGY AND MEDICINE (2004)
Decrease in oxidative stress is not related to left ventricular function improvement in patients with chronic heart failure treated with carvedilol greig d.; Castro P. ; Chiong M.; Moraga, F; Diaz-Araya, G; Vukasovic, JL; Perez, O; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2004)
Early expression of vascular transforming growth factor beta 1 (TGF beta 1) in DOCA-salt rats Reyes L.; Ocaranza, MP; Copaja M; Diaz G.; Lavandero S.; Jalil J. Abstract ISI JOURNAL OF HYPERTENSION (2004)
Gene expression of profibrotic factors in isoproterenol-treated Brown-Norway and Lewis rats Soto, MC; Bassi, RV; Saldaña A.; Ocaranza M.; Jalil J.; Chiong M.; Lavandero S.; Diaz-Araya, G Abstract MOLECULAR BIOLOGY OF THE CELL (2004)
IGF-1 prevents NF kappa B activation but not reactive oxygen species generation by hyperosmotic stress in apoptotic cultured cardiac myocytes Eisner V.; Quiroga, C; Criollo, A; Chiong M.; Diaz-Araya, G; Lavandero S. Abstract ISI FASEB JOURNAL (2004)
Influence of angiotensin-I converting enzyme polymorphism in the isoproterenol-induced extracellular matrix proteins deposition by cardiac fibroblasts. Bassi, RV; Soto, MC; Ocaranza M.; Jall, J; Chiong M.; Lavandero S.; Diaz-Araya, G Abstract ISI MOLECULAR BIOLOGY OF THE CELL (2004)
The Arg389Arg adrenergic receptor variant interacts with the Arg16Arg and Gly27Gly beta 2 adrenergic receptor variants decreasing the risk for chronic heart failure Castro P. ; greig d.; Moraga, F; Chiong M.; Diaz-Araya, G; Vukasovic, JL; Jalil J.; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2004)
Angiotensin converting enzyme polymorphism determines differential acumulation of cardiac extracelular matrix protein induced by isoproterenol in the rat Ocaranza, MP; Carreño JE; Jalil J.; Lavandero S.; Diaz-Araya, G Abstract ISI EUROPEAN HEART JOURNAL (2003)
beta 1 and beta 2-adrenergic receptor gene polymorphisms are not associated with heart failure Lavandero S.; Moraga, F; Mellado R.; Chiong M.; Diaz-Araya, G; Castro P. ; greig d.; Perez, O; Moreno, M. Abstract ISI FASEB JOURNAL (2003)
Hyperosmotic stress induces oxidative stress and NF kappa B activation in cultured cardiac myocytes Eisner, VS; Criollo, A; Quiroga, C; Chiong M.; Diaz-Araya, G; Lavandero S. Abstract ISI FASEB JOURNAL (2003)
beta(2)-adrenergic receptor polymorphisms are not associated with heart failure Lavandero S.; Moraga, F; Mario, C; Diaz-Araya, G; Vukasovic, JL; Pablo C.; Perez, O; Moreno, M.; Ocaranza, MP; Jalil J.; Ivonne, P; Nazal, C; Corbalan, R Abstract FASEB JOURNAL (2002)
Ethnic differences in beta 2 adrenergic receptor polymorphisms distribution Castro P. ; Chiong M.; Moreno, M.; Perez, O; Diaz-Araya, G; Padilla I.; Nazzal C.; Lavandero S. Abstract ISI EUROPEAN HEART JOURNAL (2002)
IGF-1 modulates cardiac fibroblast migration and adhesion through the expression and synthesis of alpha 1, beta 1-integrin and collagen Diaz-Araya, G; Carver, W; Borg, TK; Lavandero S. Abstract ISI EUROPEAN HEART JOURNAL (2002)
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in normotensive and hypertensive subjects Jalil J.; Oliveri, C; Ocaranza, MP; Godoy, I.; Cordova S; Chamorro, G; Michel, JB; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2002)
Angiotensin I-converting enzyme gene polymorphism modulates chronic hypertensive response in the rat Goldblatt model Ocaranza, MP; Piddo, AM; Faundez, P; Lavandero S.; JALIL, JE Abstract ISI HYPERTENSION (2001)
IGF-1 regulates integrin and collagen expression and cell-ECM interactions on cultured rat cardiac fibroblasts Diaz-Araya, G; CARRASCO L.; Carver, W; Lavandero S.; Borg, TK Abstract ISI HYPERTENSION (2001)
Myocardial angiotensin II generation and the angiotensin I - converting enzyme gene polymorphism in the rat Jalil J.; Ocaranza, MP; Piddo, AM; Faundez, P; Lavandero S. Abstract HYPERTENSION (2001)
PI3-K/PKB pathway on the antiapoptotic response of IGF-1 in cardiac myocytes Eltit, JM; MORALES, MP.; Sapag-Hagar, M; Lavandero S. Abstract ISI FASEB JOURNAL (2001)
Tissue neutral endopeptidase activity is inversely related to angiotensin I-converting enzyme expression in the rat Oliveri, C; Bargetto, J; Ocaranza, MP; Campos X; Faundez, P; Lavandero S.; JALIL, JE Abstract ISI HYPERTENSION (2001)
Early decrease in oxidative stress in patients with class IV heart failure after successfull medical therapy Castro P. ; Diaz G.; Lavandero S.; Nazzal C.; Perez, O; Arriagada, G; Corbalan, R; Yañez F.; Larrain, G; Jalil J. Abstract EUROPEAN HEART JOURNAL (2000)
Gene transcription associated to cardiomyocyte hypertrophy is differentially regulated by IGF-1 Gonzalez-Jara, F; Lavandero S. Abstract ISI FASEB JOURNAL (2000)


Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease Bravo-Sagua R.; Parra V.; MuÃ±oz-Cordova F.; Sanchez-Aguilera P.; Garrido V.; Contreras-Ferrat A.; Chiong M.; Lavandero S. BookWhole ISI SCOPUS International Review of Cell and Molecular Biology (2020)
Autophagy in cardiac physiology and disease Hill J.A.; Lavandero S.; Rothermel, B. A. BookWhole SCOPUS From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience: Third Edition (2012)
Regulation of autophagy by insulin/IGF-1 signaling pathways Troncoso R.; Vásquez-Trincado C.; Campo A.D.; Gatica, D; Morales P.E.; Paredes, F; Torrealba, N; Lopez-Crisosto C.; pedrozo, Z; Garda L.; Díaz-Araya G.; Battiprolu P.K.; Nemchenko A.; Ferdous, A.; Gillette, T. G.; Hill J.A.; Lavandero S. BookWhole SCOPUS International Conference on Noise and Vibration Engineering 2012, ISMA 2012, including USD 2012: International Conference on Uncerta (2012)


Polimorfismo Pro 72Arg del gen TP53 y enfermedad coronaria Pizarro, Marcela; Torrealba, Natalia; Bravo, Roberto; Gonzalez, Leticia; Lavandero, Sergio Comentario SCIELO Revista chilena de cardiología (2009)


Ácido úrico: una molécula con acciones paradójicas en la insuficiencia cardiaca Alcaino, Hernan; Greig, Douglas; Castro, Pablo; Verdejo, Hugo; Mellado, Rosemarie; Garcia, Lorena; Diaz-Araya, Guillermo; Quiroga, Clara; Chiong, Mario; Lavandero, Sergio ComunicacionBreve SCIELO SCOPUS REVISTA MEDICA DE CHILE (2011)


Heart Disease and Cancer: Are the Two Killers Colluding? Kitsis, RN; Riquelme, JA; Lavandero, S EditorialMaterial ISI SCOPUS CIRCULATION (2018)
Parkin Gone Wild Unbridled Ubiquitination Cao, DJ; Lavandero S.; Hill, JA EditorialMaterial ISI SCOPUS Circulation Research (2015)
Regulation of Cardiovascular Metabolism by Hormones and Growth Factors Ibarra, C; Lavandero S.; Estrada, M EditorialMaterial ISI SCOPUS International Journal of Endocrinology (2015)
Signaling in Cell Death, Survival, Proliferation and Degeneration Smaili, SS; Quest, AFG; hetz C.; Lavandero S. EditorialMaterial ISI CURRENT MOLECULAR MEDICINE (2013)
IKK connects autophagy to major stress pathways Criollo, A; Senovilla, L; Authier, H; Maiuri, MC; Morselli E.; Vitale, I; Kepp, O; Tasdemir, E; Galluzzi L.; Shen, SS; Tailler, M; Delahaye, N; Tesniere, A; De Stefano, D; Ben-Younes, A; Harper, F; Pierron, G; Lavandero S.; Zitvogel, L.; Israel, A.; Baud, V; Kroemer G. EditorialMaterial ISI SCOPUS Autophagy (2010)
Mechanisms of cell death: molecular insights and therapeutic perspectives Diaz, LF; Chiong M.; Quest, AFG; Lavandero S.; Stutzin A. EditorialMaterial ISI SCOPUS CELL DEATH AND DIFFERENTIATION (2005)


Mitochondrial control of cell death induced by hyperosmotic stress (vol 12, pg 3, 2007) Criollo, A; Galluzzi L.; Maiuri, MC; Tasdemir, E; Lavandero S.; Kroemer G. Errata ISI SCOPUS Apoptosis (2013)


Science and Health Policies to Tackle Chronic Diseases in Chile Bambs C.; Bravo-Sagua R.; Margozzini P.; Lavandero S. Generic ISI SCOPUS TRENDS IN ENDOCRINOLOGY AND METABOLISM (2020)


Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction Tong D.; Schiattarella G.G.; Jiang N.; May H.I.; Lavandero S.; Gillette, T. G.; Hill J.A. Letter ISI SCOPUS CIRCULATION (2019)
Dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure Reply Ocaranza, MP; Michea, L.; Chiong M.; Lavandero S.; JALIL, JE Letter ISI SCOPUS JOURNAL OF HYPERTENSION (2014)
Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome Bittner, A; Alcaino H; Castro, PF; Perez, O; Corbalan, R; Troncoso R.; Chiong M.; Mellado R.; Moraga, F; Zanolli D.; Winter, JL; Zamorano, JJ; Diaz-Araya, G; Lavandero S. Letter ISI SCOPUS International Journal of Cardiology (2010)
Uric acid, xanthine oxidase and heart failure: Unresolved issues Verdejo H.; greig d.; Castro P. ; Alcaino H; Garcia, L.; Chiong M.; Lavandero S.; Pizarro M. Letter ISI EUROPEAN JOURNAL OF HEART FAILURE (2008)


Advanced Center for Chronic Diseases (ACCDiS) FONDAP (15130011) Proyecto 2014-2019 Director(a)
EVALUATION OF RIGHT VENTRICULAR FUNCTION, VENTRICULAR REMODELING AND MICRO RNA PROFILING IN PATIENTS WITH PULMONARY ARTERY HYPERTENSION=> EFFECTS OF A FATTY ACID OXIDATION INHIBITOR FONDECYT (1141198) Proyecto 2014-2018 Coinvestigador(a)
NOGO-B ESTIMULA EL ACOPLAMIENTO ESTRUCTURAL Y FUNCIONAL RETÃ�CULO ENDOPLASMÃ�TICO-MITOCONDRIA DURANTE UNA SITUACIÃ“N DE ESTRÃ‰S DEL RETÃ�CULO EN CÃ‰LULAS HELA FONDECYT (3150510) Proyecto 2014-2017 Inv. Patrocinante
THE PROGNOSTIC ROLE OF LEFT ATRIAL AND VENTRICULAR FUNCTION AND ITS CORRELATION WITH MULTIPLE BIOMARKERS IN PATIENTS WITH NEW ATRIAL FIBRILLATION FONDECYT (1141137) Proyecto 2014-2018 Coinvestigador(a)
THE ROLE OF STIM1-ORAI1 ON THE REGULATION OF CARDIOMYOCYTE AUTOPHAGY FONDECYT (3150545) Proyecto 2014-2017 Inv. Patrocinante
"EFFECT OF PROTEASOME INHIBITION ON THE CONTENT OF MITOFUSINS 1 AND 2 AND THE PRESERVATION OF MITOCHONDRIAL FUNCTION FOLLOWING CARDIAC ISCHEMIA-REPERFUSION" FONDECYT (1130407) Proyecto 2013-2017 Coinvestigador(a)
Effect of proteasome inhibition on the content of mitofusins 1 and 2 and the preservation of mitochondrial function following cardiac ischemia-reperfusion" FONDECYT (1130407) Proyecto 2013-2016 Coinvestigador(a)
ESTUDIO DE ADENOSINA Y SU SISTEMA TRANSDUCCIONAL EN LA CARDIOMIOPATIA DIABETICA. FONDECYT (3140532) Proyecto 2013-2016 Inv. Patrocinante
MODULACION DE LA AUTOFAGIA POR EL RECEPTOR DE INOSITOL TRIFOSFATO (IP3R) EN DISTROFIA MUSCULAR DE DUCHENNE. FONDECYT (3140491) Proyecto 2013-2016 Inv. Patrocinante
Apoyo a la formación de redes internacionales entre centros de investigación PCI (Red 120003) Proyecto 2012-2013 Inv. Principal
REGULATION OF MITOCHONDRIAL DYNAMICS AND BIOENERGETICS BY INSULIN IN CARDIOMYOCYTES FONDECYT (1120212) Proyecto 2012-2016 Inv. Responsable
PAPEL DEL FACTOR TRANSCRIPCIONAL FOXO1 EN LA REGULACION DEL METABOLISMO Y LA DINAMICA MITOCONDRIAL INDUCIDA POR INSULINA. FONDECYT (3120220) Proyecto 2011-2014 Inv. Patrocinante
ROLE OF MYOCARDIAL CELLULAR ADHESION MOLECULES (VCAM-1/ICAM-1) IN CARDIOPROTECTIVE ACTIONS OF INSULIN FONDECYT (1110346) Proyecto 2011-2014 Coinvestigador(a)
GLUCOCORTICOIDES EN LA INDUCCION DE AUTOFAGIA EN CELULAS MUSCULARES . PAPEL DE LA VIA NO GENOMICA EN LA ATROFIA MUSCULAR FONDECYT (3110114) Proyecto 2010-2013 Inv. Patrocinante
Metabolismo cardiaco en la insuficiencia cardiaca crónica no isquémica y sus implicancias en el estrés oxidativo, inflamación y remodelado cardiovascular. FONDECYT (1090727) Proyecto 2009-2013 Coinvestigador(a)
Proyecto ECOS-CONICYT=> Mecanismos de transducción de señales en la autofagia. Dr Guido Kroemer (Francia). PCI (C08S01) Proyecto 2009-2011 Inv. Principal
Efecto de la dinámica mitocondrial sobre la biología muscular. Ministerio de Educación y Ciencia (PCI2007 A7 0515) Proyecto 2008-2010 Inv. Principal
En la hipertensión arterial con alto riesgo cardiovascular la activación de Rho kinasa media el remodelado patológico=> un estudio clínico y molecular experimental FONDECYT (1085208) Proyecto 2008-2011 Coinvestigador(a)
RESISTENCIA A INSULINA EN LA DIABETES TIPO II=> ESTUDIO DE NUEVOS MECANISMOS FISIOPATOLOGICOS ASOCIADOS AL DETERIORO DE LA FUNCION CARDIACA FONDECYT (1080436) Proyecto 2008-2012 Inv. Responsable
Resistencia a insulina en la diabetes tipo II=> estudio de nuevos mecanismos fisiopatológicos asociados al deterioro de la función cardiaca FONDECYT (1080436) Proyecto 2008-2011 Inv. Responsable
Rol del estrés oxidativo y de la inflamación local y sistémica en el desarrollo de fibrilación auricular en el post operatorio de cirugía cardiaca FONDECYT (1070641) Proyecto 2007-2009 Coinvestigador(a)
Center for Molecular Studies of the Cell FONDAP (1501006) Proyecto 2002-2012 Investigador(a)


Counter-regulatory renin–angiotensin system in cardiovascular disease Paz Ocaranza M.; Riquelme, J. A.; GarcÃa L.; Jalil J.E.; Chiong M.; Santos R.A.S.; Lavandero S. Review ISI SCOPUS (2020)
Emerging role of mitophagy in cardiovascular physiology and pathology Morales P.E.; Arias-Durán C.; Ávalos-Guajardo Y.; Aedo G.; Verdejo H.E.; Parra V.; Lavandero S. Review ISI SCOPUS (2020)
Looking back and thinking forwards-15 years of cardiology and cardiovascular research Kalman J.M.; Lavandero S.; Mahfoud F.; Nahrendorf M.; Yacoub M.H.; Zhao D. Review ISI SCOPUS NATURE REVIEWS CARDIOLOGY (2019)
Mitochondrial dynamics, mitophagy and cardiovascular disease Vasquez-Trincado, C; Garcia-Carvajal, I; Pennanen C.; Parra, V; Hill, JA; Rothermel BA; Lavandero S. Review ISI SCOPUS JOURNAL OF PHYSIOLOGY-LONDON (2016)
New Molecular Insights of Insulin in Diabetic Cardiomyopathy Westermeier, F; Riquelme, J. A.; Pavez, M.; Garrido, V; Diaz A.; Verdejo H.E.; Castro P.F.; Garcia, L.; Lavandero S. Review ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2016)
ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension Mendoza-Torres, E; Oyarzun A.; Mondaca-Ruff, D.; Azocar, A.; Castro P.F.; Jalil J.E.; Chiong M.; Lavandero S.; Ocaranza M.P. Review SCOPUS Therapeutic Advances In Cardiovascular Disease (2015)
Autophagy in cardiovascular biology Lavandero S.; Chiang M.; Rothermel BA; Hill, JA Review ISI SCOPUS Journal of Clinical Investigation (2015)
Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy Westermeier, F; Navarro-Marquez, M; López-Crisosto, C; Bravo Sagua R; Quiroga, C; Bustamante, M; Verdejo, HE; Zalaquett R.; Ibacache M.; Parra, V; Castro, PF; Rothermel BA; Hill, JA; Lavandero S. Review ISI SCOPUS Biochimica et Biophysica Acta - Molecular Cell Research (2015)
ER-to-mitochondria miscommunication and metabolic diseases López-Crisosto, C; Bravo Sagua R; Rodriguez-Pena, M; Mera C.; Castro, PF; Quest, AFG; Rothermel BA; Cifuentes M.; Lavandero S. Review ISI SCOPUS Biochimica et Biophysica Acta - Molecular Basis of Disease (2015)
Molecular Mechanisms of Autophagy in the Cardiovascular System Gatica, D; Chiong M.; Lavandero S.; Klionsky, DJ Review ISI SCOPUS Circulation Research (2015)
Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9) Westermeier, F; Bustamante, M; Pavez, M.; Garcia, L.; Chiong M.; Ocaranza, MP; Lavandero S. Review ISI SCOPUS Pharmacological Research (2015)
Calcium signaling in insulin action on striated muscle Contreras-Ferrat, A; Lavandero S.; Jaimovich E.; Klip, A Review ISI SCOPUS CELL CALCIUM (2014)
New insights into IGF-1 signaling in the heart Troncoso R.; Ibarra, C; Vicencio, JM; Jaimovich E.; Lavandero S. Review ISI TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Oxidative Stress and Autophagy in Cardiovascular Homeostasis Morales C.R.; pedrozo, Z; Lavandero S.; Hill J.A. Review ISI ANTIOXIDANTS & REDOX SIGNALING (2014)
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system Ocaranza, Maria Paz; Michea, Luis; Chiong, Mario; Lagos, Carlos F; Lavandero, Sergio; Jalil, Jorge E. Review ISI SCOPUS CLINICAL SCIENCE (2014)
Tumor Suppression and Promotion by Autophagy Avalos, Y; Canales, J; Bravo Sagua R; Criollo, A; Lavandero S.; Quest, AFG Review ISI SCOPUS BIOMED RESEARCH INTERNATIONAL (2014)
Cardiovascular autophagy Concepts, controversies, and perspectives Lavandero S.; Troncoso R.; Rothermel BA; Martinet, W; Sadoshima, J; Hill, JA Review ISI SCOPUS Autophagy (2013)
Diabetic cardiomyopathy and metabolic remodeling of the heart Battiprolu, PK; López-Crisosto, C; Wang, ZV; Nemchenko A.; Lavandero S.; Hill, JA Review ISI SCOPUS Life Sciences (2013)
Endoplasmic Reticulum and the Unfolded Protein Response: Dynamics and Metabolic Integration Bravo, R.; Parra, V; Gatica, D; Rodríguez, AE; Torrealba, N; Paredes, F; Wang, ZV; Zorzano, A; Hill, JA; Jaimovich E.; Quest, AFG; Lavandero S. Review ISI SCOPUS International Review of Cell and Molecular Biology (2013)
Regulation of cardiac autophagy by insulin-like growth factor 1 Troncoso R.; Diaz-Elizondo, J; Espinoza, SP; Navarro-Marquez, MF; Oyarzún, AP; Riquelme, JA; Garcia-Carvajal, I; Diaz-Araya, G; Garcia, L.; Hill, JA; Lavandero S. Review ISI SCOPUS IUBMB Life (2013)
Guidelines for the use and interpretation of assays for monitoring autophagy Klionsky, DJ; Abdalla, FC; Abeliovich, H; Abraham, RT; Acevedo-Arozena, A; ADELI, K.; Agholme, L; Agnello, M; Agostinis P.; Aguirre-Ghiso, JA; Ahn, HJ; Ait-Mohamed, O; Ait-Si-Ali, S; Akematsu, T; Akira, S; Al-Younes, HM; Al-Zeer, MA; Albert, ML; Albin, RL; Alegre-Abarrategui, J; Aleo, MF; Alirezaei, M; Almasan, A; Almonte-Becerril, M; Amano, A; Amaravadi, R; Amarnath, S; Amer, AO; Andrieu-Abadie, N; Anantharam, V; Ann, DK; Anoopkumar-Dukie, S; Aoki, H; Apostolova, N; Arancia, G; Aris, JP; Asanuma, K; Asare, NYO; Ashida, H; Askanas, V; Askew, DS; Auberger, P; Baba, M; Backues, SK; Baehrecke, EH; Bahr, BA; Bai, XY; Bailly, Y; Baiocchi, R; Baldini, G; Balduini, W; Ballabio, A; Bamber, BA; Bampton, ETW; Banhegyi, G; Bartholomew, CR; Bassham, DC; Bast, RC; Batoko, H; Bay, BH; Beau, I; Bechet, DM; Begley, TJ; Behl C.; Behrends, C; Bekri, S; Bellaire, B; Bendall, LJ; Benetti, L; Berliocchi, L; Bernardi, H; Bernassola, F; Besteiro, S; Bhatia-Kissova, I; Bi, XN; Biard-Piechaczyk, M; Blum, JS; Boise, LH; Bonaldo, P; Boone, DL; Bornhauser, BC; Bortoluci, KR; Bossis, I; Bost, F; Bourquin, JP; Boya, P; Boyer-Guittaut, M; Bozhkov, PV; Brady, NR; Brancolini, C; Brech, A; Brenman, JE; Brennand, A; Bresnick, EH; Brest, P; Bridges, D; Bristol, ML; Brookes, PS; Brown, EJ; Brumell, JH; Brunetti-Pierri, N; Brunk, UT; Bulman DE; Bultman, SJ; Bultynck G.; Burbulla, LF; Bursch, W; Butchar, JP; Buzgariu, W; Bydlowski, SP; Cadwell, K; Cahova, M; Cai, DS; Cai, JY; Cai Q.; Calabretta, B; Calvo-Garrido, J; Camougrand, N; Campanella, M; Campos-Salinas, J; Candi, E; Cao, LZ; Caplan, AB; Carding, SR; Cardoso, SM; Carew, JS; Carlin, CR; Carmignac, V; Carneiro, LAM; Carra, S.; Caruso, RA; Casari, G; Casas, C.; Castino, R; Cebollero, E; Cecconi, F; Celli, J; Chaachouay, H; Chae, HJ; Chai, CY; Chan, DC; Chan, EY; Chang, RCC; Che, CM; Chen, CC; Chen, GC; Chen, GQ; Chen M.; Chen, Q; Chen, SSL; Chen, WL; Chen X.; Chen, XM; Chen, XQ; Chen, YG; Chen, YY; Chen, YQ; Chen, YJ; CHEN, ZX; Cheng, A; Cheng, CHK; Cheng, Y; Cheong, H; Cheong, JH; Cherry, S; Chess-Williams, R; Cheung, ZH; Chevet, E; Chiang, HL; Chiarelli, R; Chiba, T; Chin, LS; Chiou, SH; Chisari, FV; Cho, CH; Cho, DH; Choi, AMK; Choi D.; Choi, KS; Choi, ME; Chouaib, S; Choubey, D; Choubey, V; Chu, CT; Chuang, TH; Chueh, SH; Chun, T; Chwae, YJ; Chye, ML; Ciarcia, R; Ciriolo, MR; Clague, MJ; Clark, RSB; Clarke, PGH; Clarke, R; Codogno, P; Coller, HA; Colombo, MI; Comincini, S; Condello, M; Condorelli, F; Cookson, MR; Coppens, GHCI; Corbalan, R; Cossart, P; Costelli, P; Costes, S; Coto-Montes, A; Couve, E.; Coxon, FP; Cregg, JM; Crespo, JL; Cronje, MJ; Cuervo, AM; Cullen, JJ; Czaja, MJ; D'Amelio, M; Darfeuille-Michaud, A; Davids, LM; Davies, FE; De Felici, M; de Groot, JF; de Haan, CAM; De Martino, L; De Milito, A; De Tata, V; Debnath, J; Degterev, A; Dehay, B; Delbridge, LMD; Demarchi, F; Deng, YZ; Dengjel, J; Dent, P; Denton, D; Deretic, V; Desai, SD; Devenish, RJ; Di Gioacchino, M; Di Paolo, G; Di Pietro, C; Diaz-Araya, G; Diaz-Laviada, I; Diaz-Meco, MT; Diaz-Nido, J; Dikic, I; Dinesh-Kumar, SP; Ding, WX; Distelhorst, CW; Diwan, A; Djavaheri-Mergny, M; Dokudovskaya, S; Dong Z.; Dorsey, FC; Dosenko, V; Dowling, JJ; Doxsey, S; Dreux, M; Drew, ME; Duan, QH; Duchosal, MA; DUFF, K; Dugail, I; Durbeej, M; Duszenko, M; Edelstein, CL; Edinger, AL; Egea, G.; Eichinger, L; Eissa, NT; Ekmekcioglu, S; El-Deiry, WS; Elazar, Z; Elgendy, M; Ellerby, LM; Eng, KE; Engelbrecht, AM; Engelender, S; Erenpreisa, J; Escalante R.; Esclatine, A; Eskelinen, EL; Espert, L; Espina, V; Fan, HZ; Fan J.; Fan, QW; Fan Z.; Fang, SY; Fang, YQ; Fanto, M; Fanzani, A; Farkas, T; Farre, JC; Faure M.; Fechheimer, M; Feng, CG; Feng J.; Feng, QL; Feng, YJ; Fesus, L; Feuer, R; Figueiredo-Pereira, ME; Fimia, GM; Fingar, DC; Finkbeiner, S; Finkel, T; Finley, KD; Fiorito, F; Fisher, EA; Fisher, PB; Flajolet, M; Florez-McClure, ML; Florio, S; Fon, EA; Fornai, F; Fortunato, F; Fotedar, R; Fowler, DH; Fox, HS; Franco, R; Frankel, LB; Fransen, M; Fuentes, JM; Fueyo, J; Fujii, J; Fujisaki, K; Fujita, E; Fukuda, M; Furukawa, RH; Gaestel, M; Gailly, P; Gajewska, M; Galliot, B; Galy, V; Ganesh, S.; Ganetzky, B; Ganley, IG; Gao FB; Gao, GF; Gao, JM; Garcia, L.; Garcia-Manero, G; Garcia-Marcos, M; Garmyn, M; Gartel, AL; Gatti, E.; Gautel, M; Gawriluk, TR; Gegg, ME; Geng, JF; Germain, M.; Gestwicki, JE; Gewirtz, DA; Ghavami, S; Ghosh P.; Giammarioli, AM; Giatromanolaki, AN; Gibson, SB; Gilkerson, RW; Ginger, ML; Ginsberg, HN; Golab, J; Goligorsky, MS; Golstein, P; Gomez-Manzano, C; Goncu, E; Gongora, C; Gonzalez, CD; González R.; Gonzalez-Estevez, C; Gonzalez-Polo, RA; Gonzalez-Rey, E; Gorbunov, NV; Gorski, S; Goruppi, S; Gottlieb, RA; Gozuacik, D; Granato, GE; Grant, GD; Green, KN; Gregorc, A; Gros, F; Grose, C; Grunt, TW; Gual, P; Guan, JL; Guan, KL; Guichard, SM; Gukovskaya, AS; Gukovsky, I; Gunst, J; Gustafsson, AB; Halayko, AJ; Hale, AN; Halonen, SK; Hamasaki, M; Han, F; Han T.; Hancock, MK; 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Wang, XJ; Wang, YJ; Wang, YP; Wang Z.; Wang, ZC; Wang, ZN; Wansink, DG; Ward, DM; Watada, H; Waters, SL; Webster, P; Wei, LX; Weihl, CC; Weiss, WA; Welford, SM; Wen, LP; Whitehouse, CA; Whitton, JL; Whitworth, AJ; Wileman, T; Wiley, JW; Wilkinson S.; Willbold, D; Williams, RL; Williamson, PR; Wouters, BG; Wu, CH; Wu, DC; Wu, WKK; Wyttenbach, A.; Xavier, RJ; Xi, ZJ; Xia, P; Xiao, GF; Xie, ZP; Xie, ZL; Xu, DZ; Xu, JZ; Xu, L; Xu, XL; Yamamoto, A; Yamashina, S; Yamashita, M; Yan, XH; Yanagida, M; Yang, DS; Yang E.; Yang, JM; Yang, SY; Yang, WN; Yang, WY; Yang, ZF; Yao, MC; Yao, TP; Yeganeh, B; Yen, WL; Yin, JJ; Yin, XM; Yoo, OJ; Yoon, G; Yoon, SY; Yorimitsu, T; Yoshikawa, Y; Yoshimori, T; Yoshimoto, K; You, HJ; Youle, RJ; Younes, A; YU L.; Yu, SW; Yu, WH; Yuan, ZM; Yue, ZY; Yun, CH; Yuzaki, M; Zabirnyk, O; Silva-Zacarin, E; Zacks, D; Zacksenhaus, E; Zaffaroni, N; Zakeri, Z; Zeh, HJ; Zeitlin, SO; Zhang, H; Zhang, HL; Zhang, JH; Zhang, JP; Zhang, L; Zhang, MY; Zhang, XD; Zhao, MT; Zhao, YF; Zhao, Y.; Zhao, ZZJ; Zheng, XX; Zhivotovsky, B; Zhong, Q; Zhou, CZ; Zhu, CL; Zhu, WG; Zhu, XF; Zhu, XW; Zhu, YG; Zoladek, T; Zong, WX; Zorzano, A; Zschocke, J; Zuckerbraun, B Review ISI AUTOPHAGY (2012)
Anabolic Androgenic Steroids and Intracellular Calcium Signaling: A Mini Review on Mechanisms and Physiological Implications Vicencio, JM; Estrada, M; Galvis D.; Bravo, R.; Contreras, AE; Rotter D.; Szabadkai G.; Hill, JA; Rothermel BA; Jaimovich E.; Lavandero S. Review MINI-REVIEWS IN MEDICINAL CHEMISTRY (2011)
Autophagy as a therapeutic target in cardiovascular disease Nemchenko A.; Chiong M.; Turer A.; Lavandero S.; Hill, JA Review ISI SCOPUS Journal of Molecular and Cellular Cardiology (2011)
Cardiomyocyte death: mechanisms and translational implications Chiong M.; Wang, ZV; pedrozo, Z; Cao, DJ; Troncoso R.; Ibacache M.; Criollo, A; Nemchenko A.; Hill, JA; Lavandero S. Review ISI SCOPUS Cell Death and Disease (2011)
Mitochondrial Dynamics: a Potential New Therapeutic Target for Heart Failure Kuzmicic J.; del Campo, A; López-Crisosto, C; Morales PE; Pennanen C.; Bravo Sagua R; Hechenleitner, J; Zepeda, R.; Castro, PF; Verdejo, HE; Parra, V; Chiong M.; Lavandero S. Review ISI SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2011)
Tuning flux: autophagy as a target of heart disease therapy Xie M.; Morales, CR; Lavandero S.; Hill, JA Review ISI SCOPUS Current Opinion in Cardiology (2011)
Ca2+, autophagy and protein degradation: Thrown off balance in neurodegenerative disease Vicencio, JM; Lavandero S.; Szabadkai G. Review ISI SCOPUS Cell Calcium (2010)
Diabetic cardiomyopathy: Mechanisms and therapeutic targets Battiprolu P.K.; Gillette, T. G.; Wang Z.V.; Lavandero S.; Hill J.A. Review SCOPUS Drug Discovery Today: Disease Mechanisms (2010)
Heart energy metabolism and its role in the treatment of heart failure Castro P. ; Gabrielli, L; Verdejo H.; greig d.; Mellado R.; Concepcion, R; Sepulveda, L; Vukasovic, JL; Garcia, L.; Pizarro M.; Pivet, D; Carrillo, C.; Tapia, F; Navarro M.; Troncoso R.; Baraona F.; Llevaneras, S; Hernandez C.; Godoy, I.; JALIL, JE; Quintana, JC; Orellana P.; Chiong M.; Lavandero S. Review REVISTA MEDICA DE CHILE (2010)
Infarto perioperatorio en cirugía no-cardíaca y dexmedetomidina Ibacache, Mauricio; Pedrozo, Zully; Fernandez, Carolina; Sánchez,Gina; Lavandero, Sergio Review SCIELO Revista chilena de cardiología (2010)
Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro, Pablo; Gabrielli, Luigi; Verdejo, Hugo; Greig, Douglas; Mellado, Rosemarie; Concepción, Roberto; Sepúlveda, Luis; Vukasovic, José Luis; Garcia, Lorena; Pizarro, Marcela; PIVET, DEISY; Carrillo, Constanza; TAPIA, FABIOLA; Navarro, Mario; Troncoso, Rodrigo; Baraona, Fernando; LLEVANERAS, SILVANA; HERNÁNDEZ, CLAUDIA; Godoy, Ivan; Jalil, Jorge E.; Quintana, Juan Carlos; Orellana, Pilar; Chiong, Mario; Lavandero, Sergio Review SCIELO REVISTA MEDICA DE CHILE (2010)
Oxidative stress and inflammation in heart failure: Mechanisms of damage and therapeutic alternatives Miranda, R.; Castro P. ; Verdejo H.; Chiong M.; Diaz-Araya, G; Mellado R.; Rojas D.; Concepcion, R; Lavandero S. Review REVISTA MEDICA DE CHILE (2007)
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling Jalil J.; Lavandero S.; Chiong M.; Ocaranza, MP Review ISI SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2005)

364

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

107

Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

JORGE JALIL

FULL PROFESSOR

ENFS CARDIOVASCULARES

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

Maria Ocaranza

Asociate Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

Clara Quiroga

Profesor Asistente Adjunto

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Douglas Greig

Médico Jefe

Cardiología

P. Universidad Católica de Chile

Santiago, Chile

Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

Zully Pedrozo

Associated Professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

Camila López

Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

Rosemarie Mellado

Jefe de carrera / Académica

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

Samuel Cordova

ESCUELA DE MEDICINA, PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Jaime Riquelme

Assistant Professor

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

Andrea del Campo

Profesor Asistente, Investigador Principal

Departamento de Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

Manuel Estrada

/Associate Professor / PI

Physiology and Biophysics

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS (ICBM), PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

Pablo Aránguiz

Jefe de Carrera

Escuela de Ciencias de la Salud

Universidad Vina del Mar

Viña del Mar, Chile

M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

Luigi Gabrielli

Profesor Asistente

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

Jovan Kuzmicic

Profesor Asistente

Departamento Salud

Universidad de Los Lagos

Osorno, Chile

Daniela Salas

Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

Ivonne Olmedo

Assistant Profesor

Programa de Fisiopatología

Universidad de Chile

Santiago, Chile

Roberto Ebensperger

Associate Professor

Pharmacy

Pontificia Universidad Católica de Chile

Santiago, Chile

Anita Gálvez

Profesor Asistente

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Juan Carlos Quintana

Médico nuclear

Radiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Eugenia Morselli

Profesor Asociado de Planta Ordinaria

Fisiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago de Chile, Chile

claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

Jose Egana

Profesor asociado

Instituto de Ingeniería Biológica y Médica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

Leticia Gonzalez

Profesional Apoyo a la Investigacion

Pontificia Universidad Católica de Chile

Santiago, Chile

César Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

Valeria Garrido

Investigador Postdoctoral

Advanced Center for Chronic Disease

Universidad de Chile

Santiago, Chile

Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Yenniffer Ávalos

Profesor Asistente

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

Karina Cereceda

Investigador post doctoral

Diagnóstico

Fundación Arturo López Pérez

Providencia, Chile

Natalia Diaz

Postdoctoral Fellow

Biofísica y Bioingeniería

Universidad de Barcelona

Barcelona , España

Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

Tatiana Adasme

Coordinadora de Estudios

Oficina de Apoyo a la Investigación Clínica

Universidad Chile

Santiago, Chile

Carlos Vio

Profesor

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Renatto Anfossi

Coordinador de Investigación

Unidad de Investigación

Hospital Regional Libertador Bernardo O'Higgins

Rancagua, Chile

Pablo Irarrazaval

Professor

Electrical Engineering

Pontificia Universidad Católica de Chile

Santiago, Chile

Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Claudia Muñoz

Postdoctorado

Universidad de Chile

Santiago, Chile

Valentina Parra

Profesora Asistente / Assistant Professor

Departamento de Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

Mario Bustamante

Docente

Universidad Mayor de Chile

Santiago, Chile

Daniel Peña

Investigador postdoctoral

Departamento de Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Pedro Ayala

Profesor investigador asistente

Departamento de Enfermedades Respiratorias

Pontificia Universidad Católica de Chile

Santiago, Chile

Paulina Donoso

Full Professor

Physiology and Biophysics

UNIVERSIDAD DE CHILE

Santiago, Chile

Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

ALEJANDRA SAN MARTIN

Professor

Medicine

Universidad Andrés Bello

Santiago, Chile

Dagoberto Soto

Investigador

Universidad Católica de Chile

santiago, Chile

JUAN VILLENA

FULL PROFESSOR

ANATOMY

FACULTA DE MEDICINA. UNIVERSIDAD DE VALPARAISO

VIÑA DEL MAR, Chile

LORENA AGUILAR

Assistant Professor

Animal Pathology

Faculty of Veterinary Medicine and Livestock Sciences, University of Chile

Santiago, Chile

Matias Monsalves

Profesor Asistente

Instituto de Ciencias de la Rehabilitación

Universidad Andrés Bello

Santiago, Chile

Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

Laura Huidobro

Encargada Investigación

Ciencias Preclínicas

Universidad Católica del Maule

Talca, Chile

Paula Valenzuela

Senior Researcher

Nuevos Materiales Avanzados

Leitat Chile

Santiago, Chile

Lorena Lobos

Principal Investigator-Associate Proffesor

Facultad of Medicine - Clinic Alemana

Universidad Del Desarrollo

santiago, Chile

Maria Lisbona

Postdoctorado

Biología

Universidad de Chile

Santiago, Chile

Lorena Mosso

profesor titular

endocrinologia

Pontificia Universidad Catolica de Chile

santiago, Chile

Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

Ismael Maldonado

Asistente de Investigación

Inmunología

Universidad de Chile

Santiago, Chile

Javier Morales

Profesor Asociado

Departamento de Ciencias y Tecnología Farmacéuticas

Universidad de Chile

Santiago, Chile

Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

Ariel Castro

Full Professor

Department of Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCION

concepciòn, Chile

Roxana Pincheira

Full Professor

Bioquímica y Biología Celular

Universidad de Concepcion

Concepción, Chile

LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Juan Miquel

Full Professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Rolando de la Cruz

Associate Professor

Faculty of Engineering and Sciences

Universidad Adolfo Ibáñez

Peñalolén, Santiago, Chile

Pablo Toro

Profesor Asociado

Psiquiatría

Pontificia Universidad Católica de Chile

Santiago, Chile

Claudia Foerster

Associate Professor

Institute of Agri-food, Animal and Environmental Sciences

Universidad de O'Higgins

San Fernando, Chile

SANDRA CORTES

ASSOCIATED PROFESSOR

PUBLIC HEALTH

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Alejandra Vives

DEPTO. SALUD PÚBLICA, UNIVESIDAD CATÓLICA DE CHILE

Santiago, Chile

daniel hevia

Investigador PhD

Inmunologia

Universidad de Chile

santiago, Chile

Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

Maite Castro

Professor

Faculty of Sciences

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

Rodrigo Herrera

Group Leader (staff member)

Combinatorial NeuroImaging Core Facility

Leibniz Institute for Neurobiology

Magdeburg, Alemania

Patricio Baeza

adjunt profesor

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaiso, Chile

Augusto Manubens

Director

Tecnical Support

BIOSONDA S.A.

Santiago, Chile

Gerald Zapata

Profesor Asociado

Química Inorgánica y Analítica

Universidad de Chile

Santiago, Chile

Eduardo Couve

Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

Rodrigo Alzamora

ASSISTANT PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD DE CHILE

Santiago, Chile

José Jiménez

Postdoc

Investigación

Fundacion Ciencia y Vida

Santiago, Chile

Cesar Oyarce Diaz

Posdtoc

MMB

UMCG

Groningen, Holanda

JULIO TAPIA

Full Professor

Program of Cellular and Molecular Biology

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Franz Villarroel

Jefe Laboratorio - PI

Departamento de Investigación del Cáncer

Fundación Arturo López Pérez

Santiago, Chile

Miguel Allende

Director

Biología

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

CESAR RAMIREZ

Assistant Professor

Institute for Biological and Medical Engineering

Pontificia Universidad Catolica de Chile

Santiago, Chile

Julio Cardenas

Associated Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

Álvaro Passi

PhD student

Research Department of Epidemiology & Public Health

University College London

London, Reino Unido

ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Manuel Valenzuela

Académico Investigador

VRA

Universidad Central de Chile

santiago, Chile

Rodrigo Maldonado

Docente Investigador

Facultad de Medicina y Ciencia

Universidad San Sebastián

Valdivia, Chile

FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Fabián Jaña

Profesor Asistente

Departamento de Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

Michelle Salazar

Asistente de Investigación

Fundación Ciencia y Tecnología para el Desarrollo (FUCITED)

Santiago, Chile

Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

Ana Rojas

Asistente de Investigación

Universidad Autónoma de Chile

Santiago, Chile

Carlos Irarrazabal

Full Professor

Fisiología

Universidad de Los Andes

Santiago, Chile

Sergio González

FACULTAD DE MEDICINA. PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

RICARDO MORENO

Profesor Titular

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

Juan Reyes

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaiso, Chile

Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

Fabian Salazar

Postdoctoral Research Fellow

Biosciences

MRC Centre for Medical Mycology, University of Exeter

Exeter, Reino Unido

Vinicius Ramos Henriques

Associate Professor

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

Carolina Ribeiro

Assistant Professor

Immunology Program

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

JENNY FIEDLER

LAB. NEUROPLASTICIDAD Y NEUROGENETICA. DEPTO BIOQUIMICA Y BIOLOGÍA MOLECULAR. FAC. CIENCIAS QUÍMICAS Y FARMACÉUTICAS. UNIVERSIDAD DE CHILE

Santiago, Chile

Jenny Blamey

Director Científico

Research and Development

FUNDACIÓN CIENTÍFICA Y CULTURAL BIOCIENCIA

Santiago, Chile

MONICA ACEVEDO

Titular Professor

Division of Cardiovascular Diseases

P. UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Hernan Lara

Profesor Titular

Bioquimica y Biologia Molecular

U DE CHILE, FAC CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Carlos Sepulveda

Investigador Postdoctoral

Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile.

Santiago, Chile

Ignacio Norambuena

Postdoctorado

Universidad de Chile

Santiago, Chile

Victor Aliaga

Postdoctorante

Universidad de O'Higgins

Santiago, Chile

Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

ALEJANDRO CORVALAN

Principal Investigator

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Mauricio Henriquez

Profesor asistente

PROGRAMA DE FISIOLOGÍA Y BIOFíSICA

Universidad de Chile / Facultad de Medicina

Santiago, Chile

Arnaldo Marín

Profesor Adjunto

Basico Clinico de Oncologia

Universidad de Chile

Santiago, Chile

Sabrina Sepúlveda

Profesor Asistente

Medicina

Universidad Mayor de Chile

Santiago, Chile

Ricardo Huilcamán

Investigador

Universidad de Chile

Santiago, Chile

María Sánchez

Académica

Biología

Universidad de Santiago de Chile

Santiago, Chile

Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

Luigi Devoto

PROFESOR TITULAR

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL,FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Edio Maldonado

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

Sergio Arancibia

Medical Science Liaison

Medical Affairs

Johnson & Johnson (Janssen Pharmaceutical)

Santiago, Chile

Sebastián Leiva

Lab Manager

Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

juan duaso

Academico

Universidad Vina del Mar

Viña del Mar, Chile

Johanna Acevedo

Profesor asociado investigador

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

Magda Díaz

Yedy Israel

Profesor Titular

Farmacologia Molecular y Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE CS QUIMICAS Y FARMACÉUTICAS, LAB. FARMACOTERAPIA GÉNICA

Santiago, Chile

paula margozzini

Associate Professor

Public Health

Pontificia Universidad Católica de Chile

Santiago, Chile

Rodrigo Morales

Postdoctoral researcher

Dept. of Medicine Solna (MedS)

Karolinska Institutet

Stockholm, Suecia

Sandra Espinoza

Coordinadora de campo clínico

Tecnología y Ciencias Farmacéuticas

Universidad de Chile

Santiago, Chile

Jaime Melendez

Prof. Asistente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

Francisco Fuentes

Profesor Asistente

Departamento de Microbiología

Universidad de Concepción

Concepción, Chile

Fernanda Sanhueza

Bioquímica

Hospital Base San José de Osorno

Osorno, Chile

SERGIO ALEJANDRO LAVANDERO GONZALEZ

Líneas de Investigación

Educación

Bioquimica, UNIVERSIDAD DE CHILE. Chile, 1993

Experiencia Académica

Adjunct Professor Other

Profesor Titular Full Time

Profesor Titular Part Time

Visiting Professor Other

Experiencia Profesional

Ayudante Full Time

Instructor Full Time

Profesor Asistente Full Time

Profesor Asociado Full Time

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