Man

Mauricio Enrique Ibacache Figueroa

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

Líneas de Investigación


Anestesiología, Farmacología, Protección Miocárdica, Manejo de dolor perioperatorio.

Educación

  •  Farmacología, UNIVERSIDAD DE CHILE. Chile, 2011

Experiencia Académica

  •   Profesor Asocicado Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2001 - At present


 

Article (38)

Assessment of the antinociceptive effect of a single fentanyl bolus dose in children: A pharmacokinetic and pharmacodynamic analysis based on the nociception level index during sevoflurane general anesthesia

Cruzat, Francisco; Ibacache, Mauricio

Article ISI
PEDIATRIC ANESTHESIA  (2024)

Characterization of the temporal profile of the antinociceptive effects of an intravenous bolus of ketamine using the analgesia nociception index in no-anesthetized adult patients

Navarrete, Victor; Ibacache, Mauricio

Article ISI
JOURNAL OF CLINICAL MONITORING AND COMPUTING  (2024)

Population pharmacokinetics of amikacin in suspected cases of neonatal sepsis

Ibacache, Mauricio; Paulos, Claudio; Toso, Alberto; Maccioni, Andrea

Article ISI
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY  (2023)

An Open-Label, Dose-Escalation Study to Assess the Safety and Efficacy of IL-22 Agonist F-652 in Patients With Alcohol-associated Hepatitis

Arab, Juan P.; Sehrawat, Tejasav S.; Simonetto, Douglas A.; Verma, Vikas K.; Feng, Dechun; Tang, Tom; Dreyer, Kevin; Yan, Xiaoqiang; Daley, William L.; Sanyal, Arun; et al.

Article ISI
HEPATOLOGY  (2020)

Incidence and risk factors of preoperative anxiety in Spanish-speaking children living in a Spanish-speaking country

Arze, Santiago; Lagos, Claudio; Ibacache, Mauricio; Zamora, Maximiliano; Gonzalez, Alejandro

Article ISI
PEDIATRIC ANESTHESIA  (2020)

Dexmedetomidine metabolic clearance is not affected by fat mass in obese patients

Rolle, A; Anderson, BJ; Quezada, N; Solari, S; Allende, F; Contreras, V; Oliveros, AM; Ibacache M

Article ISI SCOPUS
BRITISH JOURNAL OF ANAESTHESIA  (2018)

Propofol pharmacokinetic and pharmacodynamic profile and its electroencephalographic interaction with remifentanil in children.

Fuentes, Ricardo; Cortinez, L. Ignacio; Contreras, Victor; Ibacache, Mauricio; Anderson, Brian J.

Article ISI SCOPUS
Paediatric Anaesthesia  (2018)

Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism

Riquelme, JA; Westermeier, F; Hall, AR; pedrozo, Z; Ibacache M; Fuenzalida, B; Sobrevia L.; Davidson, SM; Yellon, DM; Sánchez G; et al.

Article ISI SCOPUS
PHARMACOLOGICAL RESEARCH  (2016)

Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism.

Riquelme, Jaime A; Westermeier, Francisco; Hall, Andrew R; Vicencio, José Miguel; Pedrozo, Zully; Ibacache, Mauricio; Fuenzalida, Bárbara; Sobrevia, Luis; Davidson, Sean M; Yellon, Derek M; Sánchez, Gina; Lavandero, Sergio

Article
Pharmacological research  (2016)

Rocuronium pharmacokinetics and pharmacodynamics in the adductor pollicis and masseter muscles

Vega E.A.; Solari, S; Cortínez L.I.

Article ISI SCOPUS
ACTA ANAESTHESIOLOGICA SCANDINAVICA  (2016)

Rocuronium pharmacokinetics and pharmacodynamics in the adductor pollicis and masseter muscles

Vega E.A., Ibacache M.E.; Anderson B.J., Holford N.H.G.; Nazar C.E., Solari S.; Allende F.A., Cortínez L.I.

Article
Acta Anaesthesiologica Scandinavica  (2016)

Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy.

Westermeier, Francisco; Navarro-Marquez, Mario; López-Crisosto, Camila; Bravo-Sagua, Roberto; Quiroga, Clara; Bustamante, Mario; Verdejo, Hugo E; Zalaquett, Ricardo; Ibacache, Mauricio; Parra, Valentina; Castro, Pablo F; Rothermel, Beverly A; Hill, Joseph A; Lavandero, Sergio

Article
Biochimica et biophysica acta  (2015)

Dexmedetomidine pharmacokinetics in the obese

Cortinez, L; Anderson, BJ; Holford, NHG; Puga, V; de la Fuente, N; Auad, H; Solari S., Allende; FA, Ibacache

Article
European Journal of Clinical Pharmacology  (2015)

Dexmedetomidine pharmacokinetics in the obese

Cortinez, L; Anderson, BJ; Holford, NHG; Puga, V; De La Fuente N.; Auad, H; Solari, S; Allende, FA; Ibacache M

Article ISI SCOPUS
European Journal of Clinical Pharmacology  (2015)

Dexmedetomidine-ketamine combination and caudal block for superficial lower abdominal and genital surgery in children

Ibacache, ME; Fuentes R.

Article ISI SCOPUS
Paediatric Anaesthesia  (2015)

Propofol concentration to induce general anesthesia in children aged 3-11 years with the Kataria effect-site model

Fuentes R, Cortinez; I, Ibacache; M, Concha M; Munoz, H

Article
Paediatric Anaesthesia  (2015)

Propofol concentration to induce general anesthesia in children aged 3-11 years with the Kataria effect-site model

Fuentes R.; Cortinez I; Ibacache M; Concha M.; Munoz H.

Article ISI SCOPUS
Paediatric Anaesthesia  (2015)

Propofol concentration to induce general anesthesia in children aged 3-11 years with the Kataria effect-site model.

Fuentes, Ricardo; Cortínez, Ignacio; Ibacache, Mauricio; Concha, Mario; Muñoz, Hernán

Article
Paediatric anaesthesia  (2015)

Performance of Propofol Target-Controlled Infusion Models in the Obese: Pharmacokinetic and Pharmacodynamic Analysis

De La Fuente N.; Eleveld, DJ; Oliveros A.; Crovari, F; Sepulveda P.; Ibacache M; Solari, S

Article ISI SCOPUS
ANESTHESIA AND ANALGESIA  (2014)

Performance of Propofol Target-Controlled Infusion Models in the Obese=> Pharmacokinetic and Pharmacodynamic Analysis

cortinez li, de la Fuente; N, Eleveld; DJ, Oliveros A.; Crovari F., Sepúlveda P.; Ibacache, M

Article
Anesthesia and Analgesia  (2014)

Influence of glucose metabolism on vascular smooth muscle cell proliferation.

Chiong, Mario; Morales, Pablo; Torres, Gloria; Gutiérrez, Tomás; García, Lorena; Ibacache, Mauricio; Michea, Luis

Article
VASA. Zeitschrift für Gefässkrankheiten  (2013)

Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart

Ibacache M; Sánchez G; pedrozo, Z; Galvez, F; Humeres, C.; Echevarria, G; Duaso, J.; Hassi, M; García, L.; Diaz-Araya, G; et al.

Article ISI SCOPUS
Biochimica et Biophysica Acta - Molecular Basis of Disease  (2012)

Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart

Ibacache, M; Sánchez G., Pedrozo Z.; Galvez F., Humeres C.; Echevarria, G; Duaso, J; Hassi, M; Garcia L, Diaz-Araya; G, Lavandero S

Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2012)

Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart.

Ibacache, Mauricio; Sanchez, Gina; Pedrozo, Zully; Galvez, Felipe; Humeres, Claudio; Echevarria, Ghislaine; Duaso, Juan; Hassi, Mario; Garcia, Lorena; Díaz-Araya, Guillermo; Lavandero, Sergio

Article
Biochimica et biophysica acta  (2012)

Cardiomyocyte death=> mechanisms and translational implications.

Chiong, M; Wang, Z V; Pedrozo, Z; Cao, D J; Troncoso, R; Ibacache, M; Criollo, A; Nemchenko, A; Hill, J A; Lavandero, S

Article
Cell death & disease  (2011)

Infarto perioperatorio en cirugía no-cardíaca y dexmedetomidina

Ibacache, Mauricio; Pedrozo, Zully; Fernandez, Carolina; Sanchez, Gina; Lavandero, Sergio

Article
Rev Chil Cardiol  (2010)

Remifentanil requirements during propofol administration to block the somatic response to skin incision in children and adults

Ibacache, ME

Article ISI SCOPUS
ANESTHESIA AND ANALGESIA  (2007)

Remifentanil requirements during propofol administration to block the somatic response to skin incision in children and adults

Munoz, HR; Cortinez, LI; Ibacache, ME; Altermatt, FR

Article
ANESTHESIA AND ANALGESIA  (2007)

Controlled trial of dexamethasone compared with droperidol and ondansetron for the treatment of postoperative nausea and vomiting

Ibacache, ME; Mertz, VF

Article ISI
REVISTA MEDICA DE CHILE  (2006)

Effect site concentrations of propofol producing hypnosis in children and adults: comparison using the bispectral index

Ibacache, ME; Leon, PJ

Article ISI SCOPUS
ACTA ANAESTHESIOLOGICA SCANDINAVICA  (2006)

Effect site concentrations of propofol producing hypnosis in children and adults=> comparison using the bispectral index.

Muñoz, H R; Cortínez, L I; Ibacache, M E; León, P J

Article
Acta anaesthesiologica Scandinavica  (2006)

Eficacia de la dexametasona en el tratamiento agudo de náuseas y vómitos posoperatorios: Comparación con droperidol y ondansetrón

Muñoz, Hernán R; Ibacache, Mauricio E; Mertz, Verónica F

Article SCIELO
REVISTA MEDICA DE CHILE  (2006)

Eficacia de la dexametasona en el tratamiento agudo de náuseas y vómitos posoperatorios=> Comparación con droperidol y ondansetrón

Muñoz, Hernán R; Ibacache, Mauricio E; Mertz, Verónica F

Article
Rev. méd. Chile  (2006)

Estimation of the plasma effect site equilibration rate constant (k(e0)) of propofol in children using the time to peak effect - Comparison with adults

Ibacache, ME

Article ISI SCOPUS
ANESTHESIOLOGY  (2004)

Estimation of the plasma effect site equilibration rate constant (ke0) of propofol in children using the time to peak effect=> comparison with adults.

Muñoz, Hernán R; Cortínez, Luis I; Ibacache, Mauricio E; Altermatt, Fernando R

Article
Anesthesiology  (2004)

Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children

Ibacache, ME; Brandes, V; Morales, AL

Article ISI SCOPUS
ANESTHESIA AND ANALGESIA  (2004)

Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children.

Ibacache, Mauricio E; Muñoz, Hernán R; Brandes, Verena; Morales, Anita L

Article
Anesthesia and analgesia  (2004)

Agitation after desflurane and Dixon and Massey up-and-down method.

Muñoz, Hernán R; Ibacache, Mauricio E

Article
Anesthesia and analgesia  (2003)

Letter (1)

Agitation after desflurane and dixon and massey up-and-down method

Ibacache, ME

Letter ISI
ANESTHESIA AND ANALGESIA  (2003)

Proyecto (5)

Comparison of Postoperative Nociception outcomes between NoL-guided and standard intraoperative analgesia based on Fentanyl in patients undergoing elective surgery with general anesthesia

FONDECYT (11180674)

Proyecto
2019-2021
Inv. Responsable

THE EFFECT OF OBESITY IN DEXMEDETOMIDINE METABOLIC CLEARANCE

FONDECYT (1150197)

Proyecto
2015-2018
Coinvestigador(a)

THE EFFECT OF OBESITY IN DEXMEDETOMIDINE METABOLIC CLEARANCE

FONDECYT (1150197)

Proyecto
2015-2018
Coinvestigador(a)

REGULACION REDOX DE PROTEINAS MITOCONDRIALES EN EL POSTCONDICIONAMIENTO CARDIACO

FONDECYT (1080497)

Proyecto
2008-2012
Tesista

REGULACION REDOX DE PROTEINAS MITOCONDRIALES EN EL POSTCONDICIONAMIENTO CARDIACO

FONDECYT (1080497)

Proyecto
2008-2012
Tesista

Review (6)

Modeling and Simulations in Latin-American Generic Markets: Perspectives from Chilean Local Industry, Regulatory Agency, and Academia

García, Mauricio A.; Paulos, Claudio; Vinales, Manuel Ibarra; Michelet, Robin; Cabrera-Perez, Miguel Angel; Aceituno, Alexis; Bone, Michelle; Ibacache, Mauricio; Cortinez, Luis Ignacio; Guzmán, Marcelo

Review ISI
MOLECULAR PHARMACEUTICS  (2024)

Dexmedetomidine Improves Cardiovascular and Ventilatory Outcomes in Critically Ill Patients: Basic and Clinical Approaches

Ibacache M; Cortínez I.; Vargas-Errázuriz P.

Review ISI SCOPUS
FRONTIERS IN PHARMACOLOGY  (2020)

Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy

Westermeier, F; Navarro-Marquez, M; López-Crisosto, C; Bravo Sagua R; Quiroga, C; Bustamante, M; Verdejo, HE; Zalaquett R.; Ibacache M; Parra, V; et al.

Review ISI SCOPUS
Biochimica et Biophysica Acta - Molecular Cell Research  (2015)

Influence of glucose metabolism on vascular smooth muscle cell proliferation

Chiong M.; Morales PE; Torres, G; Gutiérrez T.; García, L.; Ibacache M; Michea, L.

Review ISI SCOPUS
Vasa - Journal of Vascular Diseases  (2013)

Cardiomyocyte death: mechanisms and translational implications

Chiong M.; Wang, ZV; pedrozo, Z; Cao, DJ; Troncoso R.; Ibacache M; Criollo, A; Nemchenko A.; Hill, JA; Lavandero S.

Review ISI SCOPUS
Cell Death and Disease  (2011)

Infarto perioperatorio en cirugía no-cardíaca y dexmedetomidina

Ibacache, Mauricio; Pedrozo, Zully; Fernández, Carolina; Sánchez,Gina; Lavandero, Sergio

Review SCIELO
REVISTA CHILENA DE CARDIOLOGIA  (2010)

6
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

4
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

3
Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

3
Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

1
Clara Quiroga

Profesor Asistente Adjunto

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Luis Cortínez

Profesor Titular

DIVISIÓN DE ANESTESIOLOGÍA

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Sandra Solari

Profesor Clinico Asociado

Laboratorios Clinicos

Facultad de Medicina - PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Mario Bustamante

Docente

Universidad Mayor de Chile

Santiago, Chile

1
Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Jaime Riquelme

Assistant Professor

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

1
Nicolás Quezada

Adjunct Researcher

Digestive Surgery

Pontificia Universidad Catolica de Chile

Santiago, Chile

3
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

1
Rodrigo Castillo

Profesor Asistente

Medicina Interna Oriente

University of Chile

Santiago, Chile

1
Jorge Farias

Full Professor

Chemical Engineering

Universidad de La Frontera

Temuco, Chile

1
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

4
Victor Contreras

Director y Gestor de Proyectos

Anestesiologia

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Fidel Allende

Quimico

Laboratorios Clinicos

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

3
Zully Pedrozo

Associated Professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

1
Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Camila López

27
Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

1
Mauricio García

Assistant Professor

Departamento de Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Alberto Toso

Médico asistencial

Neonatología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
FERNANDO CROVARI

Jefe Departamento

Cirugía Digestiva

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
RODRIGO CARRASCO

Miembro titular

Sociedad Chilena de Cardiologia y Cirugia Cardiovascular

Oberageri, Suiza

1
juan duaso

Academico

Universidad Vina del Mar

Viña del Mar, Chile

1
Paula León

Médico Clínico

Anestesiología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Miguel Cabrera

Académico

Departamento de Ciencias Farmacéuticas

Universidad Católica del Norte

Antofagasta, Chile

1
GLORIA TORRES

Investigadora Postdoctoral

CIIB

Universidad de Los Andes

Santiago, Chile

1
Daniel Ramos

Médico

Medicina Respiratoria

Instituto Nacional del Tórax

Santiago, Chile