Man

Juan Carlos Prieto Domínguez

Profesor Titular

Universidad de Chile

Santiago, Chile

Líneas de Investigación


Enfermedades cardiovasculares, Farmaco-epidemiología, Estatinas, Isquemia-reperfusión miocárdica, Infarto agudo de miocardio, Estrés oxidativo, Conducción de ensayos clínicos

Educación

  •  Médico cirujano, UNIVERSIDAD DE CHILE. Chile, 1983
  •  Cardiólogo, CONACEM. Chile, 1994
  •  Farmacólogo Clínico, UNIVERSIDAD DE CHILE. Chile, 1997

Experiencia Académica

  •   Profesor titular Full Time

    UNIVERSIDAD DE CHILE

    Facultad de Medicina

    Santiago, Chile

    1990 - At present

Experiencia Profesional

  •   Profesor titular Full Time

    Universidad de Chile

    Santiago, Chile

    1990 - At present

  •   Cardiólogo Clínico Part Time

    Hospital Clínico Universidad de Chile

    Santiago, Chile

    1990 - At present

Premios y Distinciones

  •   Presidente Sociedad Chilena Cardiología y Cirugía Cardiovascular

    SOCIEDAD CHILENA DE CARDIOLOGIA Y CIRUGIA CARDIOVASCULAR

    Chile, 2018

    Presidente electo SOCHICAR


 

Article (55)

Involvement of NO in Antinociception of NSAIDS in Murine Formalin Hind Paw Assay

Noriega V.; Miranda, H. F.; Prieto, J. C.; Sotomayor-Zárate R.; Sierralta F.

Article ISI SCOPUS
Drug Research  (2020)

Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome: ODYSSEY OUTCOMES Trial

Jukema, J. W.; Szarek M.; Zijlstra L.E.; de Silva H.A.; Bhatt, D. L.; Bittner V.A.; Diaz R.; Edelberg J.M.; Goodman, S. G.; Hanotin C.; Harrington, R. A.; Karpov Y.; Moryusef A.; Pordy R.; Prieto, J. C.; Roe, M. T.; White, H. D.; Zeiher A.M.; Schwartz G.G.; Steg, P. G.; ODYSSEY OUTCOMES Committees and Investigators

Article SCOPUS
Journal of the American College of Cardiology  (2019)

Interleukin-1beta in synergism gabapentin with tramadol in murine model of diabetic neuropathy

Miranda, H. F.; Poblete P.; Sierralta F.; Noriega V.; Prieto, J. C.; Zepeda R.J.

Article ISI SCOPUS
INFLAMMOPHARMACOLOGY  (2019)

Nitric Oxide and Opioids Involvement in Isobolographic Nsaids Antinociception

Miranda, H. F.; Noriega V.; Sierralta F.; Poblete P.; Aranda N.; Prieto, J. C.

Article WOS-ESCI SCOPUS
Drug Research  (2019)

Non-steroidal Anti-inflammatory Drugs in Tonic, Phasic and Inflammatory Mouse Models

Miranda, H. F.; Noriega V.; Sierralta F.; Poblete P.; Aranda N.; Prieto, J. C.

Article WOS-ESCI SCOPUS
Drug Research  (2019)

Pharmacological interaction between NSAIDS with clomipramine and risperidone in mice visceral pain

Vargas C.G.; Miranda, H. F.; Sierralta F.; Noriega V.; Prieto, J. C.

Article ISI SCOPUS
DRUG DEVELOPMENT RESEARCH  (2019)

Stroke in Patients With Peripheral Artery Disease: Insights From the EUCLID Study

Kolls B.J.; Sapp S.; Rockhold F.W.; Jordan J.D.; Dombrowski K.E.; Fowkes F.G.R.; Mahaffey, K. W.; Berger J.S.; Katona B.G.; Blomster J.I.; Norgren L.; Abramson B.L.; Leiva-Pons J.L.; Prieto, J. C.; Sokurenko G.; Hiatt W.R.; Jones W.S.; Patel M.R.

Article ISI SCOPUS
STROKE  (2019)

Antinociception induced by rosuvastatin in murine neuropathic pain

Miranda, HF; Sierralta F.; Aranda N.; Poblete P.; Castillo, RL; Noriega, V; Prieto, JC

Article ISI SCOPUS
PHARMACOLOGICAL REPORTS  (2018)

Synergism between gabapentin–tramadol in experimental diabetic neuropathic pain

Miranda, H. F.; Sierralta F.; Aranda N.; Poblete P.; Noriega V.; Prieto, J. C.

Article ISI SCOPUS
Fundamental and Clinical Pharmacology  (2018)

Antinociceptive interaction of gabapentin with minocycline in murine diabetic neuropathy

Miranda H.F.; Sierralta F.; Jorquera V.; Poblete P.; Prieto J.C.; Noriega V.

Article ISI SCOPUS
INFLAMMOPHARMACOLOGY  (2017)

Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty

Ramos, Cristóbal; Brito, Roberto; González-Montero, Jaime; Valls, Nicolás; Gormaz, Juan G.; Prieto, Juan C.; Aguayo, Rubén; Puentes, Ángel; Noriega, Viviana; Pereira, Gonzalo; Palavecino, Tamara; Rodrigo, Ramón

Article ISI SCOPUS
ARCHIVES OF MEDICAL SCIENCE  (2017)

Amelioration of persistent left ventricular function impairment through increased plasma ascorbate levels following myocardial infarction

Valls, N; Gormaz, JG; Aguayo, R; González, J; Brito, R; Hasson, D; Libuy, M; Ramos, C; Carrasco, R; Prieto, JC; Dussaillant, G; Puentes, A; Noriega, V; Rodrigo, R

Article ISI SCOPUS
REDOX REPORT  (2016)

Antinociceptive Interaction of Tramadol with Gabapentin in Experimental Mononeuropathic Pain

Miranda, HF; Noriega, V; Prieto, JC; Zanetta, P; Castillo, R; Aranda, N; Sierralta, F

Article ISI SCOPUS
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY  (2016)

Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio

Jorge Bartolucci; Carolina Nazzal N.; Fernando J. Verdugo; Juan Carlos Prieto; Pablo Sepúlveda; Ramon Corbalan

Article SCIELO SCOPUS
REVISTA MEDICA DE CHILE  (2016)

Pharmacological profile of dexketoprofen in orofacial pain

Miranda, HF; Sierralta, F; Aranda, N; Noriega, V; Prieto, JC

Article ISI SCOPUS
PHARMACOLOGICAL REPORTS  (2016)

Antinociceptive Synergism of Gabapentin and Nortriptyline in Mice with Partial Sciatic Nerve Ligation

Miranda, HF; Noriega V.; Zepeda, R.; Zanetta P.; Prieto-Rayo, J; Prieto, JC; Sierralta F.

Article ISI SCOPUS
Pharmacology  (2015)

Involvement of nitridergic and opioidergic pathways in the antinociception of gabapentin in the orofacial formalin test in mice

Miranda, H. F.; Sierralta F.; Lux S.; Troncoso R.; Ciudad N.; Zepeda, R.; Zanetta P.; Noriega V.; Prieto, J. C.

Article ISI SCOPUS
PHARMACOLOGICAL REPORTS  (2015)

Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain

Miranda, HF; Noriega V.; Zanetta P.; Prieto, JC; Prieto-Rayo, JC; Aranda N.; Sierralta F.

Article ISI SCOPUS
JOURNAL OF BIOMEDICAL SCIENCE  (2014)

The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trial

Rodrigo R.; Hasson D.; Prieto, JC; DUSSAILLANT, G; Ramos C.; Leon, L.; Garate, J; Valls, N.; Gormaz, JG

Article ISI SCOPUS
TRIALS  (2014)

Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain

Miranda, H. F.; Noriega V.; Zanetta P.; Prieto, J. C.

Article ISI SCOPUS
JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE  (2013)

Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain

Miranda HF, Noriega V; Zanetta P, Prieto JC

Article
Journal Orofacial Pain  (2013)

Systemic synergism between codeine and morphine in three pain models in mice

 Miranda HF, Noriega V; Zepeda R, Sierralta F

Article
Pharmacological Reports  (2013)

Effect of Carvedilol and Nebivolol on Oxidative Stress-related Parameters and Endothelial Function in Patients with Essential Hypertension

Zepeda R.J.; Castillo R.; Rodrigo R.; Prieto, J. C.; Aramburu, I; Brugere, S; Galdames K.; Noriega V.; Miranda, H. F.

Article ISI SCOPUS
Basic & clinical pharmacology & toxicology  (2012)

Previous administration of naltrexone did not change synergism between paracetamol and tramadol in mice

Miranda, H. F.; Noriega V.; Prieto, J. C.

Article ISI SCOPUS
Pharmacology Biochemistry and Behavior  (2012)

Synergism Between Fentanyl and Tramadol in Tonic Inflammatory Pain: the Orofacial Formalin Test

Miranda, H. F.; Noriega V.; Zepeda R.J.; Sierralta F.; Prieto, J. C.

Article ISI SCOPUS
Inflammation  (2012)

Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes

Tricoci, P.; Huang Z.; Held, C; Moliterno D.J.; Armstrong P.W.; Van de Werf, F; White, H. D.; Aylward P.E.; Wallentin L.; Chen E.; Lokhnygina, Y; Pei, J; Leonardi S.; Rorick T.L.; Kilian A.M.; Jennings L.H.K.; Ambrosio G.; Bode, C; Cequier, A; Cornel J.H.; Díaz R; Erkan A.; Huber K.; Hudson M.P.; Jiang L.; Jukema, J. W.; Lewis B.S.; Lincoff A.M.; Montalescot, G; NICOLAU J.C.; Ogawa, H.; Pfisterer, M; Prieto, J. C.; Ruzyllo, W; Sinnaeve P.R.; Storey R.F.; Valgimigli, M; Whellan D.J.; Widimsky P.; Strony, J; Harrington, R. A.; Mahaffey, K. W.

Article ISI SCOPUS
New England Journal of Medicine  (2012)

Antinociception and Anti-Inflammation Induced by Simvastatin in Algesiometric Assays in Mice

Miranda, HF; Noriega V.; Olavarria, L.; Zepeda RJ; Sierralta F.; Prieto, JC

Article ISI SCOPUS
Basic & clinical pharmacology & toxicology  (2011)

Antinociception induced by atorvastatin in different pain models

Garcia, GG; Miranda, HF; Noriega V.; Sierralta F.; Olavarria, L.; Zepeda RJ; Prieto, JC

Article ISI SCOPUS
Pharmacology Biochemistry and Behavior  (2011)

Interaction between dexibuprofen and dexketoprofen in the orofacial formalin test in mice

Miranda, HF; Noriega V.; Sierralta F.; Prieto, JC

Article ISI SCOPUS
Pharmacology Biochemistry and Behavior  (2011)

Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists

Gonzalez, Claudia; Zegpi, Carlos; Noriega, Viviana; Prieto, Juan C.; Miranda, Hugo F.

Article ISI
PHARMACOLOGICAL REPORTS  (2011)

Synergism between COX-3 inhibitors in two animal models of pain

Muñoz J; Navarro, C.; Pinardi, G; Sierralta F.; Prieto, J. C.; Miranda, H. F.; Noriega V.

Article SCOPUS
Inflammopharmacology  (2010)

(TTA)n Polymorphism in 3-Hydroxy-3-Methylglutaryl-Coenzyme A and Response to Atorvastatin in Coronary Artery Disease Patients

Noriega V.; Pennanen C.; Sanchez, MP; Chiong M.; Llancaqueo, M; Lavandero S.; Prieto, JC

Article ISI SCOPUS
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY  (2009)

Effects of tramadol and dexketoprofen on analgesia and gastrointestinal transit in mice

Miranda, HF; Puig, MM; Romero, MA; Prieto, JC

Article ISI SCOPUS
FUNDAMENTAL CLINICAL PHARMACOLOGY  (2009)

Synergism between NSAIDs in the orofacial formalin test in mice

Miranda, HF; Sierralta F.; Prieto, G.

Article ISI SCOPUS
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR  (2009)

The Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRA.CER) trial: study design and rationale

Harrington, RA; Van de Werf, F; Armstrong, PW; Aylward, P; Veltri, E; Mahaffey, KW; Moliterno, DJ; Strony, J; Wallentin L.; White, HD; Díaz R; Huber K.; Nicolau, JC; Prieto, JC; Isaza, D; Widimsky P.; Grande, P; Nieminen, M; Montalescot, G; Bode, C; Wong, L; Ofner, P; Lewis, BS; Ambrosio G.; Valgimigli, M; Ogawa, H.; Yamaguchi, J; Jukema, JW; Cornel, JH; Nordrehaug, JE; Ruzyllo, W; Providencia, L; Tan, HC; Dalby, A; Seung-Jung, P; Betriu, A; Cequier, A; Held, C; Pfisterer, M; Ming-Fong, C; Timurkaynak, T; Storey, RF; Chen E.; Hudson, MP; Lincoff, AM; Morrow, DA; Tricoci, P.; Whellan, D

Article ISI
AMERICAN HEART JOURNAL  (2009)

Isobolographic analysis of multimodal analgesia in an animal model of visceral acute pain

Miranda, HF; Prieto, JC; Puig, MM; Pinardi, G

Article ISI SCOPUS
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR  (2008)

Lack of effect of atorvastatin or pravastatin on the endothelium-dependent relaxation in segments of human vessels

Prieto, J. C.; Zamorano J.; Larrain, E; Castillo R.; Espinoza J.; Pinardi, G; Zepeda R.J.; Miranda, H. F.

Article SCOPUS
International Journal of Pharmacology  (2008)

Mortalidad intrahospitalaria en hombres y mujeres según terapias de reperfusión en infarto agudo del miocardio con supradesnivel del ST

Prieto, Juan Carlos; Sanhueza, Consuelo; Martínez, Nicolás; Nazzal, Carolina; Corbalán Ramón; Cavada, Gabriel; Lanas, Fernando; Bartolucci, Jorge; CAMPOS, PABLA

Article SCIELO
REVISTA MEDICA DE CHILE  (2008)

The impact of Chilean health reform in the management and mortality of ST elevation myocardial infarction (STEMI) in Chilean hospitals

Nazzal N C, Campos T P, Corbalán H R, Lanas Z F, Bartolucci J J, Sanhueza C P, Cavada Ch G, Prieto D JC

Article
REVISTA MEDICA DE CHILE  (2008)

Dexketoprofen-induced antinociception in animal models of acute pain: Synergy with morphine and paracetamol

Miranda, HF; Puig, MM; Dursteler, C; Prieto, JC; Pinardi, G

Article ISI SCOPUS
NEUROPHARMACOLOGY  (2007)

Influencia del sistema nitridérgico en la respuesta contráctil a fenilefrina de anillos de vasos usados en revascularización coronaria

Prieto, Juan C.; Pinardi, Gianni; Zamorano, Jaime; Larrain, Ernesto; Bermúdez, Cristian; Castillo, Rodrigo; Cisternas, Verónica; Miranda, Hugo F.

Article SCIELO
REVISTA MEDICA DE CHILE  (2007)

Modification of phenylephrine induced contraction of human vessel rings by L-arginine and L-arginine methyl ester

Prieto JC, Pinardi G, Zamorano J, Larrain E, Bermudez C, Castillo R, Cisternas V, Miranda HF

Article
 (2007)

Synergism between paracetamol and nonsteroidal anti-inflammatory drugs in experimental acute pain

Miranda, HF; Puig, MM; Prieto, JC; Pinardi, G

Article ISI SCOPUS
PAIN  (2006)

Utilidad de la terapia trombolítica con estreptokinasa a dosis baja en infarto agudo del miocardio

Raffo G, Carlos; Bartolucci J, Jorge; Corbalán H, Ramón; Aninat H, Mauricio; Torres, H. Humberto; Prieto D, Juan Carlos; Lanas Z, Fernando; Chávez S, Eduardo; Cumsille G, Francisco; Nazzal N, Carolina

Article SCIELO
REVISTA MEDICA DE CHILE  (2006)

Analgesic synergism between intrathecal morphine and cyclooxygenase-2 inhibitors in mice

Pinardi, G; Prieto, JC; Miranda, HF

Article ISI SCOPUS
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR  (2005)

Hypotensive effect of dopamine: synergism induced by fenoldopam or levodopa

Prieto, JC; Quevedo, M.; Miranda, HF; Pinardi, G

Article ISI SCOPUS
Acta Cardiologica  (2005)

Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento

Corbalán H, Ramón; Nazzal N, Carolina; Eggers R, Germán; Bartolucci J, Jaime; Prieto D, Juan Carlos; Alcaino I, Milton; Stockins F, Benjamín; Campos P, Pabla; Dapelo A, Alejandro

Article ISI SCIELO
REVISTA MEDICA DE CHILE  (2004)

Reduction of Myocardial Infarction Mortality in Chilean Hospitals

Corbalan R, Nazzal C, Prieto JC, Chavez E et al.

Article
REVISTA MEDICA DE CHILE  (2002)

Cardiovascular risk factors in middle-age women with acute coronary syndromes

Blümel JE, Prieto JC, Leal T, Cruz MN, Gallardo L

Article
 (2001)

Changes in the patterns of drug prescription for acute myocardial infarct. Comparison of 2 periods

Prieto JC, Corbalan R, Nazzal C, Chavez E et al.

Article
REVISTA MEDICA DE CHILE  (2001)

Safety profile of statins

Prieto, JC

Article
REVISTA MEDICA DE CHILE  (2001)

Isobolographic analysis of the interaction between fenoldopam and levodopa on arterial blood pressure of the rat

Quevedo, M.; Prieto, JC; Miranda, HF; Pinardi, G

Article ISI SCOPUS
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY  (2000)

Bedside markers of coronary artery patency and short-term prognosis of patients with acute myocardial infarction and thrombolysis

Corbalan, R; Prieto, JC; Chavez, E; Nazzal, C; Cumsille, F; Krucoff, M

Article ISI
AMERICAN HEART JOURNAL  (1999)

The beta 2 receptor plays a role in the hypotensive effect of L-dopa.

Quevedo M, Prieto JC, Pérez-Olea J

Article
ACTA PHYSIOLOGICA PHARMACOLOGICA ET THERAPEUTICA LATINOAMERICANA  (1995)

Surrogate end points: the case of trials on coronary atherosclerotic plaque regression

Marchioli R, Prieto JC, Tognoni G

Article
CLINICAL TRIALS AND META-ANALYSIS  (1994)

Abstract (1)

Differences in treatment and in-hospital mortality of acute myocardial infarction patients in public and private hospitals in Chile before and after healthcare guarantees

Nazzal C.; Corbalan, R; Frenz, P; Sepúlveda P.; Prieto, J.

Abstract ISI
EUROPEAN HEART JOURNAL  (2013)

Proyecto (1)

PREVENTION OF REPERFUSION DAMAGE ASSOCIATED WITH PERCUTANEOUS CORONARY ANGIOPLASTY FOLLOWING ACUTE MYOCARDIAL INFARCTION

FONDECYT (1120594)

Proyecto
2012-2015
Investigador(a)

Review (1)

Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n-3 fatty acids: molecular mechanisms and potential clinical applications

Rodrigo R.; Prieto, JC; Castillo R.

Review ISI SCOPUS
Clinical Science  (2013)

55
Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

11
Viviana Noriega

Profesional

Hospital Clinico Universidad de Chile

Santiago, Chile

6
Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

3
angelo ramos

medico radiologo

centro imagenolgia

Hospital Clinico Universidad De Chile

santiago, Chile

3
Ramón Rodrigo

PROFESOR TITULAR

INSTITUTO DE CIENCIAS BIOMÉDICAS

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA

Santiago, Chile

2
Rubén Aguayo

Director de Departamento Medicina Interna Occidente

Departamento de Medicina Interna Occidente

Universidad de Chile

Santiago, Chile

2
Rodrigo Castillo

Profesor Asistente

Medicina Interna Oriente

University of Chile

Santiago, Chile

2
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

2
Jaime Gonzalez

Académico

Departamento de Oncología Básico Clínico

Universidad de Chile

Independencia, Chile

2
Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

1
RODRIGO CARRASCO

Miembro titular

Sociedad Chilena de Cardiologia y Cirugia Cardiovascular

Oberageri, Suiza

1
Gonzalo Pereira

Médico radiólogo

Radiología

Hospital Clinico Universidad de Chile

Santiago, Chile

1
Matias Libuy

RESEARCH ASSISTANT

Programa de Políticas, Sistemas y Gestión en Salud

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Nicolás Valls

Medico Anestesiologo

Anestesiología y medicina perioperatoria

Hospital CLinico Universidad de Chile

Santiago, Chile

1
Fernando Verdugo

Cardiologo

Cardiologia

Hospital del Salvador

Santiago, Chile

1
Ramón Sotomayor

Full Professor

Institute of Physiology

UNIVERSIDAD DE VALPARAÍSO, FACULTAD DE CIENCIAS, DEPARTAMENTO DE FISIOLOGÍA

Valparaíso, Chile

1
Fernando Lanas

Profesor titular

Medicina Interna

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Gabriel Cavada

Académico, Jefe de Programa

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

1
Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
María Sánchez

Académica

Biología

Universidad de Santiago de Chile

Santiago, Chile

1
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile