Man

Renatto Claudio Anfossi Matus

Coordinador de Investigación

Hospital Regional Libertador Bernardo O'Higgins

Rancagua, Chile

Líneas de Investigación


Educación

  •  Químico Farmacéutico, UNIVERSIDAD DE CHILE. Chile, 2016

Experiencia Académica

  •   Investigador Full Time

    UNIVERSIDAD DE CHILE

    Ciencias Químicas y Farmacéuticas

    Santiago, Chile

    2016 - 2017

  •   Investigador Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Chile

    2017 - 2019

  •   Investigador Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    Chile

    2016 - 2016

Experiencia Profesional

  •   Investigador Full Time

    Universidad de Chile

    Chile

    2017 - 2019

  •   Coordinador de Investigación Full Time

    Hospital Regional Libertador Bernardo O'Higgins

    Rancagua, Chile

    2022 - At present


 

Article (13)

Interferon-β decreases LPS-induced neutrophil recruitment to cardiac fibroblasts
Lipoxin A4 prevents high glucose-induced inflammatory response in cardiac fibroblast through FOXO1 inhibition
SGK1 is necessary to FoxO3a negative regulation, oxidative stress and cardiac fibroblast activation induced by TGF-β1
Statins change the cytokine profile in Trypanosoma cruzi-infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition
FoxO1 is required for high glucose-dependent cardiac fibroblasts into myofibroblast phenoconversion
In cardiac fibroblasts, interferon-beta attenuates differentiation, collagen synthesis, and TGF-beta 1-induced collagen gel contraction
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-?1
TGF-beta 1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts
Expression and function of TLR4-induced B1R bradykinin receptor on cardiac fibroblasts
Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression
IFN-beta Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation
Lipopolysaccharide Activates Toll-Like Receptor 4 and Prevents Cardiac Fibroblast-to-Myofibroblast Differentiation
Cardiac fibroblast cytokine profiles induced by proinflammatory or profibrotic stimuli promote monocyte recruitment and modulate macrophage M1/M2 balance in vitro

Proyecto (4)

CHEMICAL-BIOLOGICAL STUDY (IN VITRO AND IN VIVO) OF NEW ANALOGUES OF TRIAZOLOPYRIDINES AS ANTI-TRYPANOSOME CRUZI, THE EFFECT ON STEROL PATHWAYS
HYPERGLYCEMIA REQUIRES FOXO1, CTGF AND TGF-ß1 TO INDUCE A PROFIBROTIC AND PROINFLAMMATORY PHENOTYPE IN CARDIAC FIBROBLASTS: NEW ANTIDIABETIC ROLE OF LIPOXINA4.
MYOFIBROBLAST IN THE LUNG AFTER INSTILLATION OF WHOLE GASTRIC JUICE IN A RAT MODEL: A NORMAL REPARATIVE PROCESS OR A STARTING POINT FOR THE DEVELOPMENT OF CHRONIC FIBROSIS?.
ROLE OF TLR4 AND INFLAMMASOME IN THE DIFFERENTIATION AND ACQUISITION OF A PROINFLAMMATORY PHENOTYPE OF ADULT RAT CARDIAC MYOFIBROBLAST
17
Renatto Anfossi

Coordinador de Investigación

Unidad de Investigación

Hospital Regional Libertador Bernardo O'Higgins

Rancagua, Chile

8
Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

5
Fabiola González

Investigadora Postdoctoral

Universidad de Chile

Santiago, Chile

5
Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

5
Claudia Muñoz

Postdoctorado

Universidad de Chile

Santiago, Chile

4
Francisco Olivares

Pharmacology PhD(c)

Department of Pharmaceutical and Toxicological Chemistry

Universidad de Chile

Santiago, Chile

4
Mabel Catalán

Profesora Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

3
Pablo Aránguiz

Jefe de Carrera

Escuela de Ciencias de la Salud

Universidad Vina del Mar

Viña del Mar, Chile

2
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

2
Viviana Pardo

Profesional docente

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

1
Pedro Ayala

Profesor investigador asistente

Departamento de Enfermedades Respiratorias

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Paula Valenzuela

Senior Researcher

Nuevos Materiales Avanzados

Leitat Chile

Santiago, Chile

1
Christian Castillo

Profesor Asistente

Instituto Ciencias Biomédicas

Universidad de Chile

Santiago, Chile